Ryan H Kirkpatrick, Kristina Nazzicone, Aleksandar Biorac, Anneke R Froentjes, Sarah M Simpson, Sonja Molin
{"title":"Prevalence of ocular manifestations in cutaneous rosacea: Systematic review and meta-analysis.","authors":"Ryan H Kirkpatrick, Kristina Nazzicone, Aleksandar Biorac, Anneke R Froentjes, Sarah M Simpson, Sonja Molin","doi":"10.1016/j.jcjo.2025.04.005","DOIUrl":"10.1016/j.jcjo.2025.04.005","url":null,"abstract":"<p><strong>Objective: </strong>Ocular rosacea (OR) is a rosacea subtype, typically presenting as dry eye, foreign body sensation, and photophobia. Prevalence estimates of OR in cutaneous rosacea (CR) range from 0.03% to 65%. This systematic review and meta-analysis consolidate the prevalence of diagnosed OR within CR and ocular involvement of CR.</p><p><strong>Methods: </strong>Primary research studies reporting the prevalence of OR in adults with CR were eligible for inclusion. Embase, MEDLINE, Web of Science, ProQuest, and Cochrane Central Register of Controlled Trials (CENTRAL) were searched. The Joanna Briggs Institute Critical Appraisal tool for Prevalence Studies and a Peters' regression test assessed risk of bias. Results were analyzed through random intercept logistic regression models using R. Studies reporting diagnosed OR were analyzed separately from those reporting ocular involvement.</p><p><strong>Results: </strong>28 studies were identified, 11 reported on diagnosed OR, and 17 reported on ocular involvement in CR. Prevalence of diagnosed OR (N = 124 093) was 10.3%, whereas the prevalence of ocular involvement in CR (N = 1 747) was 44.3%. In diagnosed OR, publication year significantly contributed to variations in reported OR prevalence, with more recent studies reporting a lower prevalence of diagnosed OR compared to older studies.</p><p><strong>Discussion: </strong>This study highlights the variability in reported prevalences of OR and ocular involvement in CR. This might be explained by a lack of clear guidelines on how to diagnose and refer patients with CR and co-occurring ocular signs and symptoms. Greater clinician awareness and clear referral guidelines are warranted.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144076232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lindsay Wise, Hanan Safa Fakhruddin, Asim F Choudhri, Nir Shimony, Stephanie Einhaus, Lauren C Ditta
{"title":"Profound vision loss secondary to malignant intracranial hypertension following a multifocal intracranial hemorrhage in an adult with Alagille Syndrome.","authors":"Lindsay Wise, Hanan Safa Fakhruddin, Asim F Choudhri, Nir Shimony, Stephanie Einhaus, Lauren C Ditta","doi":"10.1016/j.jcjo.2025.03.017","DOIUrl":"10.1016/j.jcjo.2025.03.017","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brendan K Tao, Sidrat Rahman, Dana Toameh, Edsel Ing, Christian El-Hadad
{"title":"ETDRS-style distance visual acuity charts for Indigenous Canadians: development and validation using Canadian Aboriginal syllabics.","authors":"Brendan K Tao, Sidrat Rahman, Dana Toameh, Edsel Ing, Christian El-Hadad","doi":"10.1016/j.jcjo.2025.04.004","DOIUrl":"10.1016/j.jcjo.2025.04.004","url":null,"abstract":"<p><strong>Objective: </strong>To develop and validate a logMAR Early Treatment Diabetic Retinopathy Study (ETDRS)-style visual acuity chart imprinted with Canadian Aboriginal Syllabics (CAS) optotypes.</p><p><strong>Design: </strong>Prospective, nonrandomized, within-subject analysis.</p><p><strong>Participants: </strong>22 Indigenous patients from the Ullivik residence (Montreal, QC) for Inuit patients who were able to interpret Latin and CAS characteristics.</p><p><strong>Methods: </strong>Python and LaTeX scripts were created to generate PDFs of standard ETDRS charts, which could be readily modified for alphabet (CAS or Latin), font, and optotype sizing. We used CAS characters that were preserved across Cree, Ojibwe, and Inuktitut languages. A 60\" television screen (4K resolution) was used to display the eye charts to scale. For each subject, the best-corrected visual acuity (BCVA) of each eye was assessed on each chart (4 measurements per patient).</p><p><strong>Results: </strong>The median difference between visual acuities (logMAR) acquired by the Latin and CAS charts was 0 (Q1: -0.08; Q3: 0). Band-Altman analysis revealed a bias of -0.01 (SD: 0.03), which was near zero (indicating favourable agreement), and one outlier (of 22 patients), whose deviation was attributed to random error. The visual acuity differences between eye charts were not statistically significant (p = 0.1).</p><p><strong>Conclusions: </strong>We developed and validated the first CAS-imprinted ETDRS chart for measuring visual acuity. Given its use of preserved characters across Cree, Ojibwe, and Inuktitut languages, this chart has additional applicability to several Indigenous populations in Canada. Future work should develop near reading cards and other methods of optimizing culturally competent eye care for Indigenous patients.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesca Lee, Zaynab Somani, Eric S Tam, Hannah H Chiu, Lili Tong, Steve Arshinoff, Sohel Somani
{"title":"Cost analysis of immediate versus delayed bilateral cataract surgery in seniors in community-based ambulatory surgical centers in a post-COVID-19 era.","authors":"Francesca Lee, Zaynab Somani, Eric S Tam, Hannah H Chiu, Lili Tong, Steve Arshinoff, Sohel Somani","doi":"10.1016/j.jcjo.2025.04.010","DOIUrl":"10.1016/j.jcjo.2025.04.010","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the cost-savings of immediately sequential bilateral cataract surgery versus delayed sequential bilateral cataract surgery among seniors at a Canadian community-based ambulatory surgical center in the post-COVID-19 era.</p><p><strong>Design: </strong>Prospective chart review.</p><p><strong>Participants: </strong>Seniors aged 60 and older undergoing cataract extraction surgery at a community-based ambulatory surgical center in Ontario.</p><p><strong>Methods: </strong>Direct and indirect cost metrics were collected from 202 patients who underwent either delayed sequential bilateral cataract surgery (DSBCS) or immediately sequential bilateral cataract surgery (ISBCS) at 1 of 2 community-based ambulatory surgical center (ASCs) between January 2022 and January 2023. Direct cost measures included preoperative, intraoperative, and postoperative surgical expenses. Preoperative measures included diagnostic and consultation fees. Intraoperative metrics consisted of medical and nonmedical labor, anesthesia fees, and consumables (including amortized cost of equipment and sterilization). Postoperative surgical costs included the first postoperative follow-up visit and a postoperative visit at week 1 (POW1). Indirect costs were measured by the cost of travel and additional postoperative visits (any visits other than required for the first postoperative visit and POW1). Additional economic factors included total time spent travelling and total duration of travel.</p><p><strong>Results: </strong>The average costs were reduced by $375.22 CAD when performing ISBCS (p < 0.001), totaling to $1260.33 versus DSCBS's total cost of $1635.55. Specifically, direct surgical costs were $1487.95 for DSBCS and $1176.93 for ISBCS (p < 0.001), whereas indirect costs were $147.60 for DSBCS versus $83.40 for ISBCS (p < 0.001).</p><p><strong>Conclusions: </strong>The average costs of cataract extraction among senior patients in ambulatory surgical centers were significantly lower for ISBCS compared to DSBCS.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meira Fogel Levin, Giuseppe Querques, Riccardo Sacconi, Jason M L Miller, Mark W Johnson, Alexandra Miere, Eric Souied, Anne Kunkler, Nicolas A Yannuzzi, Adrian T Fung, K Bailey Freund, Tommaso Bacci, Prithvi Ramtohul, Lawrence Yannuzzi, SriniVas R Sadda, Caroline R Baumal, Panos Christakis, R Rishi Gupta, Michael Ip, Ahmad Santina, Adrian Au, David Sarraf
{"title":"Central bouquet hemorrhage with Henle fiber layer extension in myopic eyes.","authors":"Meira Fogel Levin, Giuseppe Querques, Riccardo Sacconi, Jason M L Miller, Mark W Johnson, Alexandra Miere, Eric Souied, Anne Kunkler, Nicolas A Yannuzzi, Adrian T Fung, K Bailey Freund, Tommaso Bacci, Prithvi Ramtohul, Lawrence Yannuzzi, SriniVas R Sadda, Caroline R Baumal, Panos Christakis, R Rishi Gupta, Michael Ip, Ahmad Santina, Adrian Au, David Sarraf","doi":"10.1016/j.jcjo.2025.03.019","DOIUrl":"10.1016/j.jcjo.2025.03.019","url":null,"abstract":"<p><strong>Objective: </strong>To characterize the clinical and multimodal imaging features of central bouquet hemorrhage (CBH) with Henle fiber layer (HFL) involvement in highly myopic eyes, and to investigate the relationships between hemorrhage characteristics, reabsorption time, and visual outcomes.</p><p><strong>Methods: </strong>Multicenter, retrospective analysis of highly myopic eyes with CBH involving the HFL, confirmed by optical coherence tomography (OCT).</p><p><strong>Results: </strong>Eighteen eyes from 18 subjects were included for analysis. The mean age of the cohort was 39 ± 13.7 years (range: 17-69) and 61% of subjects were female. Mean refractive error was -14.8 ± 3.14 diopters (range: -9 D to -22 D). All eyes demonstrated a combined CBH with HFL component, while a subretinal component was present in 83.3% of cases. Myopic choroidal neovascularization (CNV) was excluded in all eyes using optical coherence tomography angiography (OCTA) or dye-based angiography (fluorescein or indocyanine green). No correlation was observed between hemorrhage size and visual outcomes or reabsorption time. Hemorrhage cleared after a mean of 2.63 months, and the radial HFL hemorrhage component resolved first. All eyes showed improvement in visual acuity from baseline. Persistent OCT alternations after resolution of hemorrhage included ellipsoid zone disruption (88.9%) and hyperreflective changes in HFL (77.8%). Anti-VEGF injections were administered to 6 eyes (33.3%) and did not correlate with a significant visual or anatomical benefit.</p><p><strong>Conclusion: </strong>CBH with HFL involvement in high myopia was associated with significantly improved visual outcomes from baseline but structural alterations can persist after clinical resolution. The size of the hemorrhage did not correlate with resorption time, and anti-VEGF treatment did not affect outcome. These findings provide new insights into the natural history and management of nonneovascular CBH in highly myopic eyes.</p>","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143976102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ryan S Huang, Andrew Mihalache, Michael Balas, Marko M Popovic, Clara C Chan
{"title":"Comparative corneal safety of mitomycin C, 5-fluorouracil, and interferon α-2b: a population-based pharmacovigilance analysis.","authors":"Ryan S Huang, Andrew Mihalache, Michael Balas, Marko M Popovic, Clara C Chan","doi":"10.1016/j.jcjo.2025.05.010","DOIUrl":"10.1016/j.jcjo.2025.05.010","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pratima R Vishwakarma, Rushil H Ambani, Anna M Stagner, Roberto Pineda
{"title":"Intraocular lens opacification due to calcium deposition after glaucoma filtration device placement.","authors":"Pratima R Vishwakarma, Rushil H Ambani, Anna M Stagner, Roberto Pineda","doi":"10.1016/j.jcjo.2025.05.012","DOIUrl":"10.1016/j.jcjo.2025.05.012","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gilles C Martin, Isabelle Hardy, Simon Trottier, Frédéric Mouriaux, Issam Tanoubi
{"title":"From a task-trainer to an immersive operating-room experience: upgrading a cataract surgery simulator to enhance soft-skills training.","authors":"Gilles C Martin, Isabelle Hardy, Simon Trottier, Frédéric Mouriaux, Issam Tanoubi","doi":"10.1016/j.jcjo.2025.04.001","DOIUrl":"10.1016/j.jcjo.2025.04.001","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143977930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nadine Cheffi, Emaan Chaudry, Jobanpreet Dhillon, Adil Bhatti
{"title":"Racial and ethnic diversity at the Canadian Ophthalmological Society annual meetings.","authors":"Nadine Cheffi, Emaan Chaudry, Jobanpreet Dhillon, Adil Bhatti","doi":"10.1016/j.jcjo.2025.04.015","DOIUrl":"10.1016/j.jcjo.2025.04.015","url":null,"abstract":"","PeriodicalId":9606,"journal":{"name":"Canadian journal of ophthalmology. Journal canadien d'ophtalmologie","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143984742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}