Case Reports in Surgery最新文献

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Recurrence Leiomyosarcoma of the Popliteal Vein: A Rare Soft Tissue Sarcoma. 腘静脉雷米肉瘤复发:一种罕见的软组织肉瘤
IF 0.6
Case Reports in Surgery Pub Date : 2023-02-16 eCollection Date: 2023-01-01 DOI: 10.1155/2023/2788584
Thanate Poosiripinyo, Sermsak Sukpanichyingyong, Krits Salang, Chat Sumananont, Thanapon Chobpenthai
{"title":"Recurrence Leiomyosarcoma of the Popliteal Vein: A Rare Soft Tissue Sarcoma.","authors":"Thanate Poosiripinyo, Sermsak Sukpanichyingyong, Krits Salang, Chat Sumananont, Thanapon Chobpenthai","doi":"10.1155/2023/2788584","DOIUrl":"10.1155/2023/2788584","url":null,"abstract":"<p><strong>Background: </strong>Leiomyosarcoma (LMS) is a soft tissue sarcoma that originates from smooth muscle cells and constitutes approximately 5-10% of all soft tissue sarcomas. Vascular LMS is the least common subtype of LMS. About one-third of vascular LMS is located in the extremities, most commonly in the saphenous vein (25%). Vascular LMS originating from the popliteal vein is very rare, and to the best of our knowledge, only nine cases have been reported to date. <i>Case presentation</i>. We herein report a case of a 49-year-old woman who presented with recurrence of a mass that was located at the posterior aspect of the right proximal leg and extended to the popliteal fossa. She had mild pain and intermittent claudication without a history of an edematous leg. The tissue diagnosis was LMS. Wide en bloc resection of the tumor, including the segment of the involved popliteal vein, was performed without venous reconstruction. The patient received no other adjuvant treatments. At the 16-month follow-up, she had good oncologic and functional outcomes.</p><p><strong>Conclusion: </strong>Vascular LMS at the popliteal vein is uncommon but should be considered as a differential diagnosis in a patient who presents with a mass at the popliteal fossa. The magnetic resonance imaging (MRI) and core needle biopsy were needed for a definite diagnosis. The mainstay of treatment is wide en bloc resection of the tumor, including the involved segment of the vein. Venous reconstruction after resection is unnecessary in chronic cases without a history of an edematous leg. Radiotherapy is an important adjuvant for local control when the surgical margins are close or positive. The role of chemotherapy in systemic management remains unclear.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"2788584"},"PeriodicalIF":0.6,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949943/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10782333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Massive Haematochezia due to Splenic Artery Bleeding into the Colon: Unusual Manifestation of Advanced Pancreatic Cancer. 脾动脉大出血致大量赤血病:晚期胰腺癌的不寻常表现。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/7443508
R Sguinzi, F Pugin, C Bader, A Meyer, L Buhler, L Widmer, D Staudenmann, B Egger
{"title":"Massive Haematochezia due to Splenic Artery Bleeding into the Colon: Unusual Manifestation of Advanced Pancreatic Cancer.","authors":"R Sguinzi,&nbsp;F Pugin,&nbsp;C Bader,&nbsp;A Meyer,&nbsp;L Buhler,&nbsp;L Widmer,&nbsp;D Staudenmann,&nbsp;B Egger","doi":"10.1155/2023/7443508","DOIUrl":"https://doi.org/10.1155/2023/7443508","url":null,"abstract":"<p><p>We describe a case of an uncommon early pancreatic cancer presentation in a patient in his 60s who had haemorrhagic shock from extensive haematochezia and required blood transfusions as well as surveillance in an intensive care unit. A splenic artery pseudoaneurysm that had been effectively embolized by angiography was seen to be actively bleeding into the colon lumen on a computerized tomography (CT) scan along with a necrotic mass of the pancreatic tail. A pancreatic mucinous adenocarcinoma was diagnosed by a transgastric biopsy. A pancreatico-colic fistula was discovered by CT scan after a colic contrast enema. A transabdominal drainage of the necrotic collection and targeted antibiotic treatment had been performed with a satisfying patient outcome. In order to assess a potential secondary surgical resection, systemic chemotherapy was planned. In conclusion, haematochezia with hemodynamic instability originated from a splenic artery pseudoaneurysm fistulising into the colon (arterio-colic fistula) and sepsis originating from a tumoral pancreatic abscess fistulising into the colon (tumoral pancreatico-colic fistula).</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"7443508"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9851798/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10582876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review. 胆囊透明细胞癌1例报告及文献复习。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/8104679
Panayiotis Papatheodorou, Kyriakos Frantzeskou, Kyriaki Konstantinou, Elena Theophanous
{"title":"Gallbladder Clear Cell Carcinoma: Report of a Rare Case and Literature Review.","authors":"Panayiotis Papatheodorou,&nbsp;Kyriakos Frantzeskou,&nbsp;Kyriaki Konstantinou,&nbsp;Elena Theophanous","doi":"10.1155/2023/8104679","DOIUrl":"https://doi.org/10.1155/2023/8104679","url":null,"abstract":"<p><p>Carcinoma of the gallbladder is the most common biliary tract cancer. The majority of gallbladder cancers are adenocarcinomas, whereas clear-cell carcinoma of the gallbladder (CCG) is a rarely recorded variant. Usually, diagnosis is established incidentally after cholecystectomy, performed for another reason. Clinically, the different histological types of carcinomas are impossible to be recognized preoperatively, since they present with a wide and common range of symptoms. We present a male patient who underwent an emergency cholecystectomy due to suspected perforation. After an uneventful postoperative period, the histopathological report led to the diagnosis of CCG, but the surgical margins were infiltrated by the tumor. The patient decided not to proceed with any additional treatment and passed away 8 months after the operation. In conclusion, it is of great necessity to record such unusual cases and enriches global knowledge with information clinically and educationally noteworthy.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"8104679"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10314819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10104562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hepatocellular Neoplasm of Uncertain Potential of Malignancy or Well-Differentiated Hepatocellular Carcinoma Arising within Hepatocellular Adenoma. 肝细胞腺瘤中出现的恶性潜能不确定的肝细胞肿瘤或分化良好的肝细胞癌。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/2831510
Elisabete Campos, Roberto Silva, Sara Rodrigues, Marinho de Almeida, Joanne Lopes, Marisa Aral, Humberto Cristino, Luís Graça, Elisabete Barbosa
{"title":"Hepatocellular Neoplasm of Uncertain Potential of Malignancy or Well-Differentiated Hepatocellular Carcinoma Arising within Hepatocellular Adenoma.","authors":"Elisabete Campos,&nbsp;Roberto Silva,&nbsp;Sara Rodrigues,&nbsp;Marinho de Almeida,&nbsp;Joanne Lopes,&nbsp;Marisa Aral,&nbsp;Humberto Cristino,&nbsp;Luís Graça,&nbsp;Elisabete Barbosa","doi":"10.1155/2023/2831510","DOIUrl":"https://doi.org/10.1155/2023/2831510","url":null,"abstract":"<p><strong>Background: </strong>Hepatocellular adenoma (HCA) is an uncommon solid, solitary, benign liver lesion that develops in an otherwise normal-appearing liver. Hemorrhage and malignant transformation are the most important complications. Risk factors for malignant transformation include advanced age, male gender, use of anabolic steroids, metabolic syndrome, larger lesions, and beta-catenin activation subtype. The identification of higher risk adenomas enables the selection of patients most suitable for aggressive treatment and those who benefit with surveillance, minimizing the risks for these predominantly young patients. <i>Case Presentation</i>. We present the case of a 29-year-old woman with a history of oral contraceptive intake for 13 years, which was sent to evaluation in our Hepato-Bilio-Pancreatic and Splenic Unit because of a large nodular lesion in segment 5 of the liver, compatible with HCA, and was proposed to surgical resection. Histological and immunohistochemical investigation revealed an area with atypical characteristics, suggesting malignant transformation.</p><p><strong>Conclusions: </strong>HCAs share similar imaging characteristics and histopathological features with hepatocellular carcinomas; therefore, immunohistochemical and genetic studies assumes great importance to discriminate adenomas with malignant transformation. Beta-catenin, glutamine synthetase, glypican-3, and heat-shock protein 70 are promising markers to identify higher risk adenomas.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"2831510"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10328728/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9801578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare Presentation of Small Bowel Obstruction Secondary to Intestinal Leiomyoma in a Patient with Crohn's Disease. 克罗恩病患者肠平滑肌瘤继发小肠梗阻的罕见表现。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/8008712
Benjamin J Behers, Brett M Behers, Ryan C Perez, Kabir Grewal, Joe Cyriac, Joanne Makar, Russell W Novak
{"title":"Rare Presentation of Small Bowel Obstruction Secondary to Intestinal Leiomyoma in a Patient with Crohn's Disease.","authors":"Benjamin J Behers,&nbsp;Brett M Behers,&nbsp;Ryan C Perez,&nbsp;Kabir Grewal,&nbsp;Joe Cyriac,&nbsp;Joanne Makar,&nbsp;Russell W Novak","doi":"10.1155/2023/8008712","DOIUrl":"https://doi.org/10.1155/2023/8008712","url":null,"abstract":"<p><p>Small bowel obstructions (SBOs) are surgical emergencies that can occur with mechanical blockage of the intestinal lumen. These blockages are most commonly caused by adhesions or hernias, but can also result from intestinal neoplasms. This case report documents the rare occurrence of SBO due to a submucosal leiomyoma. This case was complicated by the patient's longstanding history of Crohn's disease, which has a considerable overlap in symptomatology with SBOs. This may have resulted in a delay in the patient's diagnosis. Leiomyomas should always be considered as a potential, albeit rare, cause of SBO.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"8008712"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10023226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9199555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complete Resection of a Torcular Herophili Hemangiopericytoma without Sinus Reconstruction: A Case Report and Review of the Literature. 圆形嗜Herophili型血管外皮细胞瘤全切除不重建鼻窦一例报告及文献复习。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/2349363
Salah-Edine Safi, Julie Godfrain, Herbert Rooijakkers, Frederic Collignon
{"title":"Complete Resection of a Torcular Herophili Hemangiopericytoma without Sinus Reconstruction: A Case Report and Review of the Literature.","authors":"Salah-Edine Safi,&nbsp;Julie Godfrain,&nbsp;Herbert Rooijakkers,&nbsp;Frederic Collignon","doi":"10.1155/2023/2349363","DOIUrl":"https://doi.org/10.1155/2023/2349363","url":null,"abstract":"<p><p>A 78-year-old woman presented to the emergency department with mild headaches and a sudden onset of blurred vision. Computerized tomography scan and magnetic resonance imaging showed what was described at first as a meningioma invading and occluding the torcular Herophili, the posterior third of the superior sagittal sinus and the proximal part of the right transverse sinus. Gross total resection of the tumor was performed without reconstructing dural sinuses. The patient was discharged home without new neurological deficit. Histopathology was in favor of a hemangiopericytoma Grade II World Health Organization (WHO). Total body positron emission tomography [<sup>18</sup>F]fluorodeoxyglucose found no secondary location. Radiotherapy was planned post-operatively.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"2349363"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10499534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10270932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Robot-Assisted Diagnostic Laparoscopy: A Safe and Feasible Adjunct to the Management of Massive Spontaneous Pneumoperitoneum. 机器人辅助诊断腹腔镜:一种安全可行的管理大量自发性气腹的辅助手段。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/4722333
Qingwen Kawaji, Sami Shoucair, Ali Darehzereshki, Alain Abdo
{"title":"Robot-Assisted Diagnostic Laparoscopy: A Safe and Feasible Adjunct to the Management of Massive Spontaneous Pneumoperitoneum.","authors":"Qingwen Kawaji,&nbsp;Sami Shoucair,&nbsp;Ali Darehzereshki,&nbsp;Alain Abdo","doi":"10.1155/2023/4722333","DOIUrl":"https://doi.org/10.1155/2023/4722333","url":null,"abstract":"<p><p>Pneumoperitoneum is the abnormal presence of free air in the peritoneal cavity. Oftentimes, it is a surgical emergency requiring exploratory laparotomy as most cases of pneumoperitoneum are due to perforated hollow viscus. However, not all pneumoperitoneum cases are surgical; nonsurgical pneumoperitoneum can arise from thoracic, abdominal, gynecologic, and other causes. We present a case of a 35-year-old male who developed a non-surgical pneumoperitoneum in the setting of drug overdose. The patient underwent robot-assisted diagnostic laparoscopy without findings of perforation or other pathology. Resolution of pneumoperitoneum was evidenced on follow-up computed tomography scan. This case emphasizes the importance of diagnostic laparoscopy in the setting of a confusing clinical picture and the feasibility of utilizing the robotic approach in hemodynamically stable patients.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"4722333"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10019970/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9199560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative Management of Mesenteric Panniculitis in a Remote Island. 偏远海岛肠系膜膜炎的保守治疗。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/3335738
Paschalis Gavriilidis, Nicola De' Angelis
{"title":"Conservative Management of Mesenteric Panniculitis in a Remote Island.","authors":"Paschalis Gavriilidis,&nbsp;Nicola De' Angelis","doi":"10.1155/2023/3335738","DOIUrl":"https://doi.org/10.1155/2023/3335738","url":null,"abstract":"<p><strong>Introduction: </strong>Mesenteric panniculitis (MP) includes a spectrum of nonspecific fibroinflammatory disorders of unknown aetiology that affects mainly the root of the mesentery. <i>Case Report</i>. A 68-year-old man is incidentally diagnosed with MP during follow-up investigation for a fusiform coeliac artery aneurysm. Four years since the diagnosis, he is completely asymptomatic. After discussing with him and presenting the current evidence, he decided not to proceed with biopsy because the finding was incidental and he is asymptomatic. Moreover, tumour markers were within the normal range. He has been scheduled for annual follow-ups with computerized tomography (CT) scans and tumour markers.</p><p><strong>Conclusions: </strong>MP is a rare chronic fibroinflammatory disease with contradictory evidence regarding its definition and management. Watchful follow-ups with CT scan and tumour markers are recommended for asymptomatic patients.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"3335738"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10147526/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9393907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Inguinal Hernia of a Ureter Belonging to a Duplex Kidney. 双肾输尿管腹股沟疝1例。
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/1285212
Mohadese Dashtkoohi, Azade Haghiri, Mohammad Sadeq Najafi
{"title":"A Rare Case of Inguinal Hernia of a Ureter Belonging to a Duplex Kidney.","authors":"Mohadese Dashtkoohi,&nbsp;Azade Haghiri,&nbsp;Mohammad Sadeq Najafi","doi":"10.1155/2023/1285212","DOIUrl":"https://doi.org/10.1155/2023/1285212","url":null,"abstract":"<p><strong>Introduction: </strong>Inguinal herniation of the ureter is a rare entity that occurs either as a complication of renal transplantation or spontaneously. Patients may suffer from obstructive uropathy or groin pain due to the unusual ectopic course of the ureter. This case report highlights the importance of recognizing a ureteroinguinal hernia.</p><p><strong>Methods: </strong>In this case report, we present a 75-year-old man with a surgical history of a right inguinal hernia repair who was referred to our center with burning left inguinal pain that persisted for two weeks. The patient's history and physical examination were consistent with an inguinal hernia. The suspected indirect inguinal hernia was found on preoperative imaging to be a tubular structure distinct from the intestine or adjacent organs. An open exploration of the inguinal canal was performed to prevent further hernia development.</p><p><strong>Results: </strong>The unusual structure in the inguinal canal turned out to be an ectopic ureter originating from the left upper pole moiety of the left duplex kidney (i.e., with duplicated ureters) and containing concentrated urine, as confirmed on a postoperative computerized tomography urogram.</p><p><strong>Conclusion: </strong>It is crucial to perform a thorough clinical examination and utilize adequate imaging modalities before surgical procedures when encountering unidentified structures.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"1285212"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10319468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9803940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluating the Presence of a Stage IV Low-Grade Well-Differentiated Neuroendocrine Tumor of the Ileocecum: A Case Report with Evaluation of Staging Protocol of Neuroendocrine Tumors and Treatment Options Based on Current Available Evidence. 评估回肠回盲IV期低级别高分化神经内分泌肿瘤的存在:基于现有证据评估神经内分泌肿瘤分期方案和治疗方案的一例报告
IF 0.6
Case Reports in Surgery Pub Date : 2023-01-01 DOI: 10.1155/2023/2919223
Vineet Madishetty, Alicia J Starr, Quyen D Chu, P A-C Brianna Starr
{"title":"Evaluating the Presence of a Stage IV Low-Grade Well-Differentiated Neuroendocrine Tumor of the Ileocecum: A Case Report with Evaluation of Staging Protocol of Neuroendocrine Tumors and Treatment Options Based on Current Available Evidence.","authors":"Vineet Madishetty,&nbsp;Alicia J Starr,&nbsp;Quyen D Chu,&nbsp;P A-C Brianna Starr","doi":"10.1155/2023/2919223","DOIUrl":"https://doi.org/10.1155/2023/2919223","url":null,"abstract":"<p><p>Neuroendocrine tumors (NET) are rare neoplasms that can originate throughout the human body. An initial treatment option includes upfront surgical resection of the primary tumor (pT) if the tumor can be localized. Current systemic therapy options following resection of the pT or with evidence of metastatic disease include somatostatin analogs, evorlimus, peptide receptor radionuclide therapy, cytotoxic chemotherapy, and interferon alpha among other less common therapy options. We present a case of a patient with a NET that originated in the ileocecal region. The patient underwent upfront surgical resection with a right hemicolectomy due to the location of the tumor. The pT was notable for extensive invasion into the visceral peritoneum and metastasis to nearby lymph nodes. However, despite being diagnosed as a stage IV NET, the Ki67 index was less than 1%, categorizing it as a low-grade well-differentiated tumor. Following resection of the tumor, there was no evidence of metastasis to the liver on the follow-up magnetic resonance imaging and recurrent somatostatin receptor overexpressing neoplasm on the Gallium-68 DOTATE PET/CT scan. Due to the juxtaposition of the low grade of the tumor and the high staging, several different treatment options were discussed with the main distinction being whether to base these options off of the stage or the grade of the tumor in the case. Low-grade well-differentiated NET have a good prognosis. On the other hand, stage IV NET and tumors that have metastasized to nearby lymph nodes and organs have an increased likelihood to reoccur and worse outcomes. Recommendations for NET based on current evidence have a lack of clarity in terms of when to undergo observation versus systemic therapy.</p>","PeriodicalId":9600,"journal":{"name":"Case Reports in Surgery","volume":"2023 ","pages":"2919223"},"PeriodicalIF":0.6,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10449591/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10110047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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