Numan Karaarslan, Hidayet Safak Cine, Ece Uysal, Bilgehan Potoglu, Mehmet Ali Kahraman, Emre Herdan, Mohammed Aladdam, Okkes Celil Gokcek, Abdullah Talha Simsek, Ercan Bosnak, Mahmut Demirkol
{"title":"Impact of Rod Material and Spinopelvic Parameters on Distal Junctional Failure Following Lumbar Fusion: A Comparative Study of Semirigid PEEK and Rigid Titanium Alloy Rods.","authors":"Numan Karaarslan, Hidayet Safak Cine, Ece Uysal, Bilgehan Potoglu, Mehmet Ali Kahraman, Emre Herdan, Mohammed Aladdam, Okkes Celil Gokcek, Abdullah Talha Simsek, Ercan Bosnak, Mahmut Demirkol","doi":"10.5137/1019-5149.JTN.47917-24.4","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.47917-24.4","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the incidence of distal junctional failure (DJF) in patients undergoing posterior lumbar fusion with either semirigid polyether ether ketone (PEEK) or rigid titanium alloy rods, focusing on the impact of preoperative and postoperative spinopelvic parameters on DJF development.</p><p><strong>Material and methods: </strong>A retrospective analysis was conducted on patients who underwent short-segment posterior transpedicular stabilization with semirigid PEEK or rigid titanium ally rods between 2015 and 2021. Preoperative and postoperative pelvic parameters, including pelvic incidence (PI), pelvic tilt (PT), sacral slope (SS), lumbar lordosis (LL), PI-LL mismatch, and lower instrumented vertebra (LIV) were evaluated.</p><p><strong>Results: </strong>The total cohort consisted of 61 patients with a mean age of 55.85 ± 11.97 years. DJF occurred in 18.03% of patients in the PEEK group (6.67%) compared to the rigid rod group (29.03%) (p < 0.05). Postoperative PI-LL mismatch was a critical factor in DJF development (p < 0.05). Among patients with a preoperative PI-LL mismatch greater than 10°, non-DJF patients achieved a correction of -55.50°. Postoperative reductions in LL were also associated with an increased risk of DJF (p < 0.05). In the PEEK group, DJF patients experienced -19.35° reduction in LL, whereas -11.02° in the rigid rod group.</p><p><strong>Conclusion: </strong>PEEK rods were associated with a lower incidence of DJF compared to rigid titanium rods. Postoperative PI-LL mismatch and changes in lumbar lordosis and PI-LL mismatch are key predictors to prevent DJF.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"222-232"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Al-Ahmari, Max Keizer, Bander Al-Dhafery, Daniëlle Eekers, Koos Hovinga, Henricus Kunst, Yasin Temel
{"title":"Tumour Shrinkage and Good Facial Nerve Function After Planned Partial Resection and Gamma Knife Radiosurgery in Koos 4 Vestibular Schwannoma.","authors":"Mohammed Al-Ahmari, Max Keizer, Bander Al-Dhafery, Daniëlle Eekers, Koos Hovinga, Henricus Kunst, Yasin Temel","doi":"10.5137/1019-5149.JTN.46381-24.1","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.46381-24.1","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate clinical and radiological outcome in surgically treated Koos 4 vestibular schwannomas.</p><p><strong>Material and methods: </strong>Volumetric analysis of the tumour volumes before surgery, after surgery (before radiation), and at follow-up time-points after radiation was performed. Clinical data on facial nerve function and complications were collected. Approximately 6 months after surgery, all patients were treated with a single fraction of stereotactic radiosurgery using the gamma knife radiosurgery with a mean marginal dose of 12.9 Gy to the residual tumour volume.</p><p><strong>Results: </strong>Mean tumour volume was 11.64 cm3 which was reduced to a mean volume of 4.17 cm3 after partial resection. After a mean follow-up of 100 months, residual tumour showed a decrease in volume in 20 patients, stable disease in one patient and two patients showed progressive tumour volume requiring a second operation in one patient. Facial nerve function was preserved in all patients. One patient suffered from a trigeminal neuralgia after radiation.</p><p><strong>Conclusion: </strong>Planned partial resection followed by radiation for patients with Koos 4 vestibular schwannoma is an effective strategy to preserve facial nerve function and achieve tumour control. Residual tumours after planned partial resection showed a mean decrease in volume of 50% at the last follow-up time point.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"265-273"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Berfu Ozdemir, Ahmet Dursun, Yadigar Kastamoni, Mehtap Ayazoglu, Onur Can Sanli, Soner Albay
{"title":"Morphometry of Latissimus Dorsi in Fetal Cadavers for Prenatal Spina Bifida Surgery.","authors":"Berfu Ozdemir, Ahmet Dursun, Yadigar Kastamoni, Mehtap Ayazoglu, Onur Can Sanli, Soner Albay","doi":"10.5137/1019-5149.JTN.44547-23.4","DOIUrl":"10.5137/1019-5149.JTN.44547-23.4","url":null,"abstract":"<p><strong>Aim: </strong>To investigate latissimus dorsi morphometry, innervation, vascularization, and variational situations in fetuses.</p><p><strong>Material and methods: </strong>Forty-nine fetuses, aged between 15 and 40 weeks of gestation, were examined for the morphological development of the latissimus dorsi. The horizontal lengths of the thoracolumbar fascia, the dimensions of the latissimus dorsi and its tendon were measured. Additionally, the attachments of the latissimus dorsi and the branching pattern of the thoracodorsal nerve were evaluated. The development of all measured parameters during gestational age (trimester) and their interrelationships were assessed. Data were compared across sides (right and left) and genders.</p><p><strong>Results: </strong>The study found that the increase in all parameters was proportional to gestational age. No significant differences were observed between sides or genders. The latissimus dorsi was directly attached (via muscle fiber) to the iliac crest in 60.2% of cases. An 88.5% attachment rate to the inferior angle of the scapula was noted, with 4.1% of these attachments being muscular. Additionally, 9.8% of latissimus dorsi tendons were found to adhere to the teres major tendon. The thoracodorsal nerve was observed to divide into 2 to 8 branches before entering the latissimus dorsi.</p><p><strong>Conclusion: </strong>We believe this study will provide valuable insights into the development of intrauterine invasive fetal procedures for tendon, muscle, and nerve transfer repair and assist in determining the most appropriate timing for intervention.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"76-89"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Umit Kocaman, Fatih Collu, Berrin Tugrul, Mesut Mete, Emre Cavusoglu, Beyhan Gurcu, Ibrahim Tuglu
{"title":"In Vitro Antitumoral Effect of Tarantula Venom Combined with Temozolomide in Human Glioblastoma Cells.","authors":"Umit Kocaman, Fatih Collu, Berrin Tugrul, Mesut Mete, Emre Cavusoglu, Beyhan Gurcu, Ibrahim Tuglu","doi":"10.5137/1019-5149.JTN.46498-24.3","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.46498-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effect of 48-hour (h) administration of Tarantula Logoplex® (TL), a homeopathic medical product containing Tarantula cubensis venom, alone and in combination with temozolomide (TMZ) on T98G glioblastoma cell line with regard to cytotoxicity, cell migration, nitric oxide synthase (NOS) level, and the type of programmed cell death pathway that mediates this cytotoxic effect.</p><p><strong>Material and methods: </strong>Cytotoxic effect was analyzed using the 3-(4,5-dimethylthiazolyl-2)-2.5-diphenyltetrazolium bromide (MTT) method, apoptosis was analyzed by Annexin V-FITC/PI flow cytometry, autophagic cell imaging was performed using the monodansylcadaverine staining method, mitochondrial membrane potential was evaluated using the tetraethylbenzimidazolylcarbocyanine iodide (JC-1) staining method, and cell migration was analyzed using the scratch test. The levels of eNOS, iNOS, and LC3 proteins were evaluated using immunofluorescence (IF) and western blot analyses. Results were compared and statistically evaluated.</p><p><strong>Results: </strong>Annexin V-FITC/PI flow cytometry revealed that the cytotoxicity of the combined administration was high and primarily (37.57%) occurred through apoptosis. According to JC-1 analysis, the apoptotic effect could have originated from mitochondria. Cell migration was lowest at the IC 50 dose of TL. The order of fluorescence intensity from the strongest to the weakest was control > TL > combination > TMZ for eNOS and control TL combination > TMZ for iNOS. Western blotting revealed the highest eNOS and iNOS protein density with TL IC 25 administration and the highest LC3 protein density with TMZ IC 50 administration.</p><p><strong>Conclusion: </strong>Combined administration of TL and TMZ may exert a significant cytotoxic effect on T98G glioblastoma cells, which may occur through apoptosis. TL may play a role in augmenting the effect of conventional therapeutic drugs on glioblastoma.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"293-308"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Unilateral Vertebroplasty in the Treatment of Osteoporotic Vertebral Compression Fractures: Effects of Cement Amount on Pain, Coronal Balance, and New Compression Fracture Formation.","authors":"Mehmet Meral, Merdan Orunoglu","doi":"10.5137/1019-5149.JTN.48236-24.3","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.48236-24.3","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the impact of the volume of cement injected during unilateral percutaneous vertebroplasty (PVP) on the occurrence of new fractures, as well as its effect on coronal balance and pain management in patients with osteoporotic vertebral compression fractures (OVCFs).</p><p><strong>Material and methods: </strong>A total of 64 OVCF patients who underwent unilateral PVP were included in this study, and categorized into two groups based on the amount of cement injected during the procedure. The first group comprised 34 patients with an injected cement volume of ?3 ml (37 levels), while the second group comprised the rest with an injected cement volume of > 3 ml (39 levels). Coronal balance changes were evaluated immediately after the procedure and at 6 months post-operatively. The incidence and timing of new fractures following the initial vertebroplasty were also analyzed.</p><p><strong>Results: </strong>No statistically significant difference was found between the two groups regarding improvement in pre- and postoperative Visual Analog Scale scores. Similarly, no significant difference was observed in the Cobb angle measurements between the groups. New fractures developed in 1 patient from the small amount cement augmented group, and in 7 patients from the large amount cement augmented group, revealing a statistically significant difference in the incidence of new fracture formation.</p><p><strong>Conclusion: </strong>A higher volume of cement injection during PVP appears to be a risk factor for the increased incidence of new fractures at other vertebral levels in patients with OVCF and these fractures typically occur within six months following the initial procedure. However, the volume of cement did not significantly affect clinical outcomes such as pain relief, mobility, or the restoration of coronal alignment.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"214-221"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Effect of Initial Treatment Modality on Oncological Outcomes in Children with Ependymoma.","authors":"Caglayan Esen, Pantea Bayatfard, Gozde Yazici, Guzide Burca Aydin, Figen Soylemezoglu, Berrin Babaoglu, Tezer Kutluk, Faruk Zorlu","doi":"10.5137/1019-5149.JTN.46386-24.2","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.46386-24.2","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the oncological outcomes and the prognostic factors for children with ependymoma who receive radiotherapy (RT) ± chemotherapy after surgery.</p><p><strong>Material and methods: </strong>The medical records of 71 children with ependymoma who received RT between 2001 and 2022 were retrospectively evaluated. Survival outcomes and prognostic factors were analyzed using log-rank and cox-regression tests. SPSS v24.0 was utilized for statistical analyses.</p><p><strong>Results: </strong>Gross total resection (GTR) was achieved in 37 (52%) patients. Craniospinal fluid (CSF) seeding was observed in 8 (11%) patients at the time of diagnosis. The median RT dose was 54 Gy (42-60 Gy). The median time from surgery to the first RT was 2.4 months (1-109 months). The median follow-up time was 65.9 months (2.5-242.8 months), and 5-y overall survival, progression-free survival (PFS), and local recurrence-free survival (LRFS) were 74%, 39%, and 46%, respectively. Recurrence was observed in 41 (58%) patients. Among patients who initiated treatment with chemotherapy, 5-y PFS and LRFS were higher in patients who received RT at the time of diagnosis than those who received RT at the progression (23% vs. 0%, p < 0.001 and 39% vs 0%, p < 0.001). In multivariate analysis, increased time from surgery to radiotherapy was found to be a poor prognostic factor for PFS.</p><p><strong>Conclusion: </strong>Young age, less than GTR, large residual tumor volume, initiation of treatment with chemotherapy after surgery, and increased time from surgery to radiotherapy may deteriorate survival. RT should not be delayed until progression, even in young patients receiving chemotherapy.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"285-292"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Supratentorial Intracranial Anomalies in Myelomeningocele Patients.","authors":"Larisa Andrada Ay, Ibrahim Alatas, Bahattin Ozkul, Revna Cetiner, Orkhan Alizada, Doga Ugurlar","doi":"10.5137/1019-5149.JTN.44183-23.7","DOIUrl":"10.5137/1019-5149.JTN.44183-23.7","url":null,"abstract":"<p><strong>Aim: </strong>To assess associated cerebral supratentorial anomalies in patients who underwent myelomeningocele repair in hopes of developing a better morphological apprehension of the forebrain?s anomalies in this category of patients.</p><p><strong>Material and methods: </strong>This retrospective observational study assessed 426 pediatric patients who underwent myelomeningocele repair between January 2013 and December 2020. Cranial MRIs with T1- and T2-weighted sequences were obtained as part of the postoperative assessment to determine the presence of associated supratentorial anomalies in pediatric patients following myelomeningocele repair.</p><p><strong>Results: </strong>The most common supratentorial anomalies identified in patients who underwent myelomeningocele repair are associated with the configuration of the corpus callosum (CC). Moreover, the complete agenesis of the CC was noticed in 9 (2.1%) subjects, whereas partial agenesis was identified in 148 (34.7%) subjects. Hypoplasia of the CC was observed in three (0.7%) patients. Gray matter heterotopia were the second most commonly observed supratentorial anomalies in 110 (25.8%) patients. Furthermore, the absence of the septum pellucidum was observed in two (0.47%) of the total patients. The widening of the interhemispheric fissure and abnormal maturation of the white matter were observed in 10 (2.34%) patients and 11 (2.58%) patients, respectively. Polymicrogyria, a consequence of abnormal cortical organization, was identified in 22.53% of the patients (96 patients) included in our series.</p><p><strong>Conclusion: </strong>This study confirms that, except for hydrocephalus and Chiari malformation, other associated cerebral supratentorial anomalies may be observed in patients with myelomeningocele. However, only limited research has confirmed the interconnection between the cerebral supratentorial anomalies and cognitive function. Therefore, this study emphasizes the necessity for further supplementary studies, in conjunction with accurate postnatal followups, in order to assess the real significance and repercussions of these anomalies on neurological development and also to establish how these structural changes in brain anatomy translate clinically.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serdar Kokar, Savas Sencan, Burak Yildiz, Berat Asim Polat, Rekib Sacaklidir, Osman Hakan Gunduz
{"title":"The Effect of Obesity on the Treatment Outcomes of Lumbar Transforaminal Epidural Steroid Injections.","authors":"Serdar Kokar, Savas Sencan, Burak Yildiz, Berat Asim Polat, Rekib Sacaklidir, Osman Hakan Gunduz","doi":"10.5137/1019-5149.JTN.45956-23.3","DOIUrl":"10.5137/1019-5149.JTN.45956-23.3","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the effects of obesity on the treatment outcomes of lumbar transforaminal epidural steroid injections (TFESIs).</p><p><strong>Material and methods: </strong>This retrospective study included patients who underwent single-level TFESI in a pain management center between January 2021 and April 2023. Body mass index (BMI) of the patients was evaluated based on the World Health Organization guidelines. Non-obese individuals had a BMI below 25 kg/m2, those with a BMI between 25 and 30 kg/m2 were classified as overweight, and those with a BMI greater than or equal to 30 kg/m2 were deemed obese. The Numeric Rating Scale (NRS) scores for all patients before the procedure, at the first hour, and at the one-month follow-up were documented. Treatment success was defined as a 50% or more reduction in NRS score at one month of follow-up.</p><p><strong>Results: </strong>This study enrolled a total of 162 participants, with a mean age of 49.5 ± 13.7 years and an average BMI of 27.7 ± 4.36 kg/m2. The mean pre-procedural pain score was 8.3 (range, 4 to 10). Significant reductions were observed in the mean pain scores at the first hour (0.90) and first month (3.3), compared to the pre-procedural NRS scores (p < .001). Upon categorizing patients based on BMI, no significant differences were observed among the groups regarding age, gender, symptom duration, procedure level, magnetic resonance imaging (MRI) grade, pain scores, and treatment success.</p><p><strong>Conclusion: </strong>Since the potential effects of obesity on the short-term results of lumbar TFESI have not been elucidated yet, practitioners should continue to apply lumbar TFESI in patients with high BMI values.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"120-128"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dawud al-Antaki's Account on Macrocephaly and Microcephaly in al-Nuzhat al-Mubhija.","authors":"Ahmet Aciduman, Abdullah Yildiz","doi":"10.5137/1019-5149.JTN.47137-24.1","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.47137-24.1","url":null,"abstract":"<p><strong>Aim: </strong>To present information regarding macrocephaly and microcephaly provided in D?w?d al-An??k??s Arabic book, al-Nuzhat al- Mubhija, which was translated into English and discussed in the context of the period?s literature.</p><p><strong>Material and methods: </strong>The copy of al-Nuzhat al-Mubhija, which was published in Egypt in 1324 AH/[1906/7 AD] (2nd edition) and another copy published in Beirut, Lebanon, in 1420 AH/1999 AD, were analyzed. The section on ?the change in the shape of the head? from the copy printed in Egypt was used as the reference and the copy printed in Lebanon was compared to it.</p><p><strong>Results: </strong>Al-An??k? presents that the change in head shape can be categorized into macrocephaly and microcephaly. Al-An??k? states that the head enlarges due to the separation of the cranial sutures, which occurs because of penetration of a humor between the sutures, accumulation of thick wind under the sutures, or trapping of fluids between the membranes. Al-An??k? recommends the use of solvents for the wind and fluids collected in the head, and surgical treatment (incision and evacuation) for cases in which fluids cannot be dissolved. However, he does not provide a detailed explanation about the surgical intervention. In this chapter, al- An??k? endeavors to provide an explanation of why microcephaly occurs, and organizes the treatment recommendations according to its proposed etiology.</p><p><strong>Conclusion: </strong>Al-An??k? briefly provides information regarding the etiology of macrocephaly and microcephaly and offers treatment suggestions for them. His treatment suggestions are in the context of and in line with the principles of humoral theory, which was the medical paradigm of the period. However, a recommendation for surgical intervention may be worth considering even in the absence of detailed information.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"202-207"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reviewers side.","authors":"Bipin Chaurasia","doi":"10.5137/1019-5149.JTN.46896-24.3","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.46896-24.3","url":null,"abstract":"<p><p>The world is unique. It revolves only around affluent peoples. They have made rules only for their own benefits. It also applies for journals. The scientific article publication in journal revolves only around journals, with authors and reviewers doing everything from back stage making them profit and supporting their business. Authors who have done hard work for their research work have to pay for publication either in the form of article processing charge (APC) or later to buy own pdf article after publication. Reviewers are also being cheated by getting nothing for their review process who also imposes substantial amount of time behind improving the authors manuscript. In return they don't even get free pdf and have to buy it later after publication.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}