Turkish neurosurgery最新文献_第5页

Retrospective Evaluation of Radiological and Clinical Postoperative Findings of Patients Who Had Endoscopic Lumbar Discectomy. 内镜下腰椎间盘切除术患者放射学和临床术后表现的回顾性评价。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.45972-23.2

Osman Boyali, Gulseli Berivan Sezen, Furkan Diren, Ercan Cetin, Mourat Chasan, Eyup Can Savrunlu, Serdar Kabatas, Erdinc Civelek, Serra Sencer, Altay Sencer

{"title":"Retrospective Evaluation of Radiological and Clinical Postoperative Findings of Patients Who Had Endoscopic Lumbar Discectomy.","authors":"Osman Boyali, Gulseli Berivan Sezen, Furkan Diren, Ercan Cetin, Mourat Chasan, Eyup Can Savrunlu, Serdar Kabatas, Erdinc Civelek, Serra Sencer, Altay Sencer","doi":"10.5137/1019-5149.JTN.45972-23.2","DOIUrl":"10.5137/1019-5149.JTN.45972-23.2","url":null,"abstract":"Aim: To evaluate the postoperative magnetic resonance imaging (MRI) findings and clinical outcomes of patients who underwent monoportal endoscopic lumbar discectomy.Material and methods: Preoperative and postoperative 3rd and 6th month MRI features, visual analog scale (VAS), and Oswestry Disability Index (ODI) scores, as well as other clinical features of patients who underwent monoportal endoscopic lumbar discectomy between August 2009 and January 2012 were retrospectively analyzed.Results: A total of 65 patients (37 female, 28 male) were included in the study. VAS and ODI scores showed significant improvement postoperatively (p < 0.001). Intervertebral disc height loss was observed only in two patients. In 31 (48%) of the 64 levels treated, no significant anterior soft tissue mass developed. However, 33 patients (52%) showed anterior epidural edema and tissue formation postoperatively. Contrast enhancement of the nerve root was found in 20 levels (29.4%), nerve root edema in 3 levels (4.41%), and nerve root displacement in 3 levels (4.41%). None of the patients had all 3 aforementioned findings concomitantly. Of the 57 levels evaluated, 36 levels (63%) showed no or minimal changes in the posterior elements, and at the 3rd month, 9 levels (15.8%) demonstrated grade 1+ changes, 9 levels showed grade 2+ changes, and grade 3+ changes were seen in only 3 levels; however, at 6-month follow-up, all vertebral levels showed improvements.Conclusion: Endoscopic discectomy is a safe and effective minimally-invasive method. However, owing to the lack of definitive radiological criteria indicating success or failure, the radiological findings should always be interpreted in conjunction with clinical outcomes.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"101-111"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Obesity on Subarachnoid Hemorrhage-Induced Cerebral Vasospasm: An Experimental Rat Model. 肥胖对蛛网膜下腔出血性脑血管痉挛的影响：一种实验性大鼠模型。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.47241-24.3

Baran Can Alpergin, Elif Gokalp, Mustafa Cemil Kilinc, Nermin Aras, Cevriye Cansiz Ersoz, Ihsan Dogan

{"title":"Impact of Obesity on Subarachnoid Hemorrhage-Induced Cerebral Vasospasm: An Experimental Rat Model.","authors":"Baran Can Alpergin, Elif Gokalp, Mustafa Cemil Kilinc, Nermin Aras, Cevriye Cansiz Ersoz, Ihsan Dogan","doi":"10.5137/1019-5149.JTN.47241-24.3","DOIUrl":"10.5137/1019-5149.JTN.47241-24.3","url":null,"abstract":"Aim: To investigate the effect of obesity on the severity of cerebral vasospasm after subarachnoid hemorrhage.Material and methods: In this study, six experimental groups, each consisting of 10 rats, were defined (60 rats in total). Groups 1 and 2 comprised rats with normal body weight, Groups 3 and 4 comprised obese rats, and Groups 5 and 6 comprised rats that returned to normal body weight after being obese. Rats in Groups 2, 4, and 6, represented the study groups, and experimental SAH was induced in them. Group 1, 3 and 5 was determined as the control group. Basilar artery lumen areas and wall thicknesses were measured and compared in all groups.Results: The luminal area of the basilar artery was significantly reduced in Groups 2, 4, and 6, than in Groups 1, 3, and 5, respectively. This indicated the development of vasospasm. No significant differences were found in the basilar artery luminal areas and wall thicknesses between Groups 1, 3, and 5. However, there were significant differences between Groups 2, 4, and 6. The basilar artery luminal area was significantly smaller in Group 4 than in Groups 2 and 6. There was no significant difference in basilar artery luminal areas between Groups 2 and 6.Conclusion: This experimental study elucidated that the severity of vasospasm subsequent to subarachnoid hemorrhage escalated in the presence of obesity, and conversely, a return to normal body weight mitigated the severity of cerebral vasospasm. Prospective clinical investigations ought to scrutinize the correlation between obesity and vasospasm, emphasizing the necessity for vigilant monitoring of vasospasm post-SAH in obese patients.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"68-75"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Protective and Therapeutic Effects of Ginger (Zingiber officinale) Extracts on Neuroinflammatory, Motor and Cognitive Impairments Caused by Mild Traumatic Brain Injury Model. 姜（Zingiber officinale）提取物对轻度创伤性脑损伤模型神经炎症、运动和认知障碍的保护和治疗作用研究。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.46057-23.7

Guven Akcay, Fikri Ozdemir, Sevil Ozkinali, Filiz Demirdogen, Ali Yilmaz

{"title":"Investigation of the Protective and Therapeutic Effects of Ginger (Zingiber officinale) Extracts on Neuroinflammatory, Motor and Cognitive Impairments Caused by Mild Traumatic Brain Injury Model.","authors":"Guven Akcay, Fikri Ozdemir, Sevil Ozkinali, Filiz Demirdogen, Ali Yilmaz","doi":"10.5137/1019-5149.JTN.46057-23.7","DOIUrl":"10.5137/1019-5149.JTN.46057-23.7","url":null,"abstract":"Aim: To examine the effects of phenolic compound-rich ginger extract on motor and cognitive functions as well as cytokine levels in the mild traumatic brain injury (mTBI) model.Material and methods: The mTBI model was modeled employing the Marmarou method. The Ginger group rats were i.p. administered 50 mg/kg of ginger extract. The Ginger+traumatic brain injury (TBI) group rats were i.p. administered 50 mg/kg of ginger extract two days before the TBI was induced. The control and TBI+Ginger group rats were provided ginger extract (50 mg/ kg i.p.) immediately after the TBI. Motor and cognitive behavioral experiments were performed. The cytokine levels were analyzed using the ELISA method.Results: While TBI caused a decline in motor and cognitive functions, significant enhancements of these functions were observed in the Ginger+TBI and TBI+Ginger groups because of the ginger treatment. While TBI induced an increased hippocampal cytokine level, significant decreases were detected in the Ginger+TBI and TBI+Ginger groups following ginger treatment.Conclusion: The study findings revealed that phenolic compound-rich ginger extract may exert therapeutic effects on cytokine levels in the mTBI model.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 2","pages":"257-264"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preoperative Stereotactic Radiosurgery for Brain Metastases: A Single-Institution Experience. 术前立体定向放射治疗脑转移瘤：单一机构的经验。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.45236-23.2

Gokhan Yaprak, Melike Pekyurek Varan, Nilsu Cini, Ugur Yilmaz, Naciye Isik, Tufan Hicdonmez

{"title":"Preoperative Stereotactic Radiosurgery for Brain Metastases: A Single-Institution Experience.","authors":"Gokhan Yaprak, Melike Pekyurek Varan, Nilsu Cini, Ugur Yilmaz, Naciye Isik, Tufan Hicdonmez","doi":"10.5137/1019-5149.JTN.45236-23.2","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.45236-23.2","url":null,"abstract":"Aim: To report a single center experience in preoperative stereotactic radiosurgery (SRS) in patients with metastatic brain tumors.Material and methods: We identified 18 patients who underwent preoperative stereotactic radiosurgery (SRS) in our clinic between 2015 and 2021. Two patients were lost to follow-up and therefore were excluded from clinical outcome analyses. SRS was administered using the CyberKnife system.Results: The median volume of index lesion was 14,19 mL (range 3,13-40,84). SRS was performed in median 1 fraction (range 1-2) to a median prescription dose of 15 Gy (range 12-17). Gross total resection was achieved in 14 (77.8%) patients. The median follow-up was 15 months (range 1-87). Median cancer specific survival (CSS) was 31 months. 6-, 12- and 24- months local control (LC) rates were 91%, 79% and 68%, respectively. Better gross tumor volume coverage was associated with better LC (p=0.01). 6-, 12- and 24- months distant brain control (DBC) rates were 82%, 58% and 47%, respectively. The infratentorial location of index lesion was associated with worse DBC (p=0.026). None of the failures were in the pattern of leptomeningeal dissemination (LMD). Grade IV symptomatic radionecrosis (RN) was reported in a single case. Three patients experienced fatal (grade V) post-operative complications.Conclusion: Preoperative SRS approach, which provides the advantage of low rates of RN and LMD, is a meritorious alternative strategy in the treatment of brain metastasis. Care must be given to better assessment of surgical mortality and the selection of appropriate patients for this treatment approach.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"35 3","pages":"474-483"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is Unilateral Extended Pterional Craniotomy Adequate Instead of Bicoronal (Bifrontal) Craniotomy in Large or Giant Olfactory Groove Meningiomas? 对于大或巨大的嗅沟脑膜瘤，单侧扩展翼面开颅比双冠状（双额）开颅更好吗？

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.46246-24.3

Hakan Yilmaz, Emrah Akcay, Alper Tabanli, Onur Bologur, Cafer Ak, Huseyin Berk Benek, Alaettin Yurt

{"title":"Is Unilateral Extended Pterional Craniotomy Adequate Instead of Bicoronal (Bifrontal) Craniotomy in Large or Giant Olfactory Groove Meningiomas?","authors":"Hakan Yilmaz, Emrah Akcay, Alper Tabanli, Onur Bologur, Cafer Ak, Huseyin Berk Benek, Alaettin Yurt","doi":"10.5137/1019-5149.JTN.46246-24.3","DOIUrl":"10.5137/1019-5149.JTN.46246-24.3","url":null,"abstract":"Aim: To evaluate the radiological characteristics, clinical features,and surgical outcomes of bicoronal incision and bifrontal craniotomy for olfactory groove meningiomas (OGMs).Material and methods: This was a retrospective review of 16 patients (nine male and seven female) with large and giant OGMs operated through unilateral extended pterional craniotomy between 2010 and 2022. The radiological characteristics, clinical features,and surgical outcomes were examined.Results: All patients underwent surgical resection via a unilateral extended pterional approach.The mean age of patients was 62.1 years. The most common presenting symptoms were altered consciousness, seizures, headache,and anosmia. Ten (62.5%) and 6 (37.5%) patients had large (4-6 cm) and giant ( > 6 cm) OGMs, respectively. The mean tumor diameter was 6.3 cm (range:4-9). Simpson Grade2 resection was achieved in all 16 patients.Conclusion: Unilateral extended pterional craniotomy offers a safe and effective alternative to the bilateral coronal approach for large and giant OGMs, minimizing risks of frontal lobe retraction, brain edema, and venous infarction. This approach allows for total resection with very low morbidity and mortality rates, making it a viable surgical approach for these complex tumors.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"56-61"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Subdural Hematoma and Tranexamic Acid: A Systematic Review. 慢性硬膜下血肿与氨甲环酸：系统综述。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.46950-24.4

Beatriz Rodrigues Messias, João Borges, Andre Felix Gentil

{"title":"Chronic Subdural Hematoma and Tranexamic Acid: A Systematic Review.","authors":"Beatriz Rodrigues Messias, João Borges, Andre Felix Gentil","doi":"10.5137/1019-5149.JTN.46950-24.4","DOIUrl":"10.5137/1019-5149.JTN.46950-24.4","url":null,"abstract":"Aim: To systematically evaluate the existing literature regarding adjuvant or primary treatment of chronic subdural hematoma (cSDH) with tranexamic acid (TXA).Material and methods: This systematic review followed the parameters set by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). A search in the available literature was conducted up to February 2024 in five databases using the keywords ?chronic subdural hematoma? and ?tranexamic acid.? Randomized clinical trials, prospective or retrospective cohorts, systematic reviews, and case series ( > five patients) relevant to the analysis were included.Results: In total, 10 studies were included, encompassing a total of 912 patients diagnosed with cSDH who underwent treatment with TXA. Seven studies evaluated the use of TXA as an adjunctive to surgical treatment, and three articles investigated the effect of TXA as primary therapy.Conclusion: TXA can be considered a safe and effective option in adjunct to surgical management. Further studies are needed to establish its role as primary treatment.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"527-536"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identification of Decompressive Craniectomy Patients with Refractory ICP using Burst Suppression Ratio and Novel Subgaleal qEEG: A Technical Note. 应用Burst Suppression Ratio和新型galal下qEEG识别顽固性ICP减压颅脑切除术患者：技术说明。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.47457-24.1

Alexander J Kim, Daniel R Felbaum, Jeffrey C Mai, Jason J Chang

{"title":"Identification of Decompressive Craniectomy Patients with Refractory ICP using Burst Suppression Ratio and Novel Subgaleal qEEG: A Technical Note.","authors":"Alexander J Kim, Daniel R Felbaum, Jeffrey C Mai, Jason J Chang","doi":"10.5137/1019-5149.JTN.47457-24.1","DOIUrl":"10.5137/1019-5149.JTN.47457-24.1","url":null,"abstract":"Decompressive hemicraniectomy (DHC) can improve outcome in patients with elevated intracranial pressure (ICP) refractory to medical therapy. However, this transition point for treating refractory ICPs with DHC is unclear as ICPs can often be controlled with escalating doses of medical management. A more individualized and precise way to monitor and define medically ?refractory ICP? may be achieved with the utilization of a quantitative electroencephalography (EEG) parameter called burst suppression ratio (BSR). This technical note describes a novel device to continuously gather EEG data from subgaleal electrodes. We present two cases where BSR (i.e. an EEG-derived marker) was associated with maximal cortical suppression, indicating refractory ICP and indication for decompression. Two patients [severe traumatic brain injury (sTBI) and ruptured arteriovenous malformation (AVM)] had BSRs measured through placement of novel subgaleal EEG electrodes. Although both patients had ICPs controlled by a combination of sedation, hyperosmolar therapy, and hypothermia, the BSR over a 20-24 hour period quickly reached almost-complete EEG suppression (BSR > 90%). Each case had different reasons for delaying DHC, however both reached maximal medical therapy. Given the limit of ICP control was reached, DHC was conducted in both cases. Patient 1 failed to recover and was compassionately extubated. Patient 2 clinically recovered and was discharged to acute rehabilitation. These cases illustrate that utilization of a novel subgaleal EEG system to continuously monitor BSR in patients who are being medically managed for ICP control may be used to select appropriate candidates for surgical decompression. In our two cases, a threshold BSR value > 90% (induced by medical therapy) was associated with the indication for DHC. This can be used in the future as another tool to define the limit of cortical suppression by medical therapy, thereby, indicating decompression.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"772-777"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cytotoxic Effects of Hypericum Perforatum on Glioblastoma Cells by Inducing Oxidative Stress, Autophagy and Apoptosis. 贯叶连翘通过诱导氧化应激、自噬和凋亡对胶质母细胞瘤细胞的细胞毒作用。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.45958-23.3

Mesut Mete, Ulkun Unlu Unsal, Fatih Collu, Isil Aydemir, Erdogan Kocamaz, Mustafa Barutcuoglu, Beyhan Gurcu, Muge Karakayali, Mehmet Ibrahim Tuglu

{"title":"Cytotoxic Effects of Hypericum Perforatum on Glioblastoma Cells by Inducing Oxidative Stress, Autophagy and Apoptosis.","authors":"Mesut Mete, Ulkun Unlu Unsal, Fatih Collu, Isil Aydemir, Erdogan Kocamaz, Mustafa Barutcuoglu, Beyhan Gurcu, Muge Karakayali, Mehmet Ibrahim Tuglu","doi":"10.5137/1019-5149.JTN.45958-23.3","DOIUrl":"10.5137/1019-5149.JTN.45958-23.3","url":null,"abstract":"Aim: To identify the autophagy mechanism T98 glioma cells.Material and methods: Three groups were created with T98 human glioblastoma cells; Group 1: T98 glioma cells without treatment (Control group). Group 2: T98 glioma cells treated with 3 µl/ml JWO. Group 3: T98 glioma cells treated with 6 µl/ml JWO. The cell proliferation, oxidative stress, types of cell death were studied at IC50 dose of JWO.Results: The proliferation of glioma cells was inhibited in 5.296 µl/ml dose. JWO induced apoptosis in T98 glioma cells in comparison with the control and there was statistically significant difference (p < 0.001). Apoptosis was analyzed via TUNEL method and results were checked by flow cytometry. We also investigated the effects of JWO on autophagy in T98 glioma cells by immunostaining LC3-II and MDC fluorescent stainings. The differences between JWO treated and control group were notably significant (p < 0.001). The immunofluorescence staining resultsof LC3-II was confirmed by Western blotting analysis.Conclusion: JWO seems to be an effective treatment agent for glioblastoma. Not only does it induce apoptosis via oxidative stress but also affects the autophagy. The use of JWO in combination with other treatment options may increase the efficacy of treatment.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"46-55"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of the Sella Morphology in Chiari Malformation Type I. I型Chiari畸形蝶鞍形态的评价。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.45939-23.3

Hakan Ozalp, Onur Ozgural, Baran Can Alpergin, Aysenur Inceoglu, Sibel Ozalp, Ercan Armagan, Hadice Ucar, Orhan Beger

{"title":"Evaluation of the Sella Morphology in Chiari Malformation Type I.","authors":"Hakan Ozalp, Onur Ozgural, Baran Can Alpergin, Aysenur Inceoglu, Sibel Ozalp, Ercan Armagan, Hadice Ucar, Orhan Beger","doi":"10.5137/1019-5149.JTN.45939-23.3","DOIUrl":"10.5137/1019-5149.JTN.45939-23.3","url":null,"abstract":"Aim: To investigate the morphology of sella turcica (ST) in Chiari malformation type I (CM-I) using computed tomography.Material and methods: The size and shape of ST were examined using the radiological images of 32 CM-I patients (21 female/11 male, mean age: 26.09 ± 15.39 years), and 32 normal participants (19 female/13 male, mean age: 28.56 ± 19.37 years).Results: The height, diameter, width, and length of ST were similar in CM-I and control groups (p > 0.05). According to the Axelsson classification, the ST shape in CM-I was identified as normal in 16 patients (50%), oblique anterior wall in 2 patients (6.25%), irregularity in 6 patients (18.75%), and pyramidal shape of the dorsum sellae in 8 patients (25%). In controls, the ST shape was identified as normal in 18 patients (56.25%), oblique anterior wall in 4 patients (12.50%), irregularity in 2 patients (6.25%), and pyramidal shape of the dorsum sellae in 8 patients (25%). According to the Camp classification, the ST shape in CM-I was identified as oval in 6 patients (18.80%), round in 21 patients (65.60%), and flattened in 5 patients (15.60%). In controls, the ST shape was identified as oval in 19 subjects (59.40%), round in 10 patients (31.30%), and flattened in 3 patients (9.40%).Conclusion: The size of ST in patients with CM-I was similar to that in healthy partcipants. The only difference in ST morphology was that patients with CM-I had more round-shaped sella, whereas normal subjects had more oval-shaped sella.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"171-181"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of Intracranial Compliance Through Noninvasive Intracranial Pressure Waveforms in Hydrocephalus Patients. A Pilot Study. 利用无创颅内压波形分析脑积水患者颅内顺应性。一项初步研究。

Turkish neurosurgery Pub Date : 2025-01-01 DOI: 10.5137/1019-5149.JTN.45668-23.2

Raphael Bertani, Stefan Koester, Caio Perret, Paulo Santa Maria, Sérgio Brasil, Gustavo Frigieri, Sávio Batista, Nicolas Nunes Rabello, Ruy Monteiro

{"title":"Analysis of Intracranial Compliance Through Noninvasive Intracranial Pressure Waveforms in Hydrocephalus Patients. A Pilot Study.","authors":"Raphael Bertani, Stefan Koester, Caio Perret, Paulo Santa Maria, Sérgio Brasil, Gustavo Frigieri, Sávio Batista, Nicolas Nunes Rabello, Ruy Monteiro","doi":"10.5137/1019-5149.JTN.45668-23.2","DOIUrl":"10.5137/1019-5149.JTN.45668-23.2","url":null,"abstract":"Aim: To assess the changes of intracranial pressure waveforms (ICPW) acquired noninvasively in a set of acute hydrocephalus patients prior to and posterior to interventions.Material and methods: Patients with clinical and radiological diagnosis of hydrocephalus were evaluated for alterations in ICPW by means of a system that detects cranial micro expansions just before and immediately after interventions. The system quantified the difference between ICPW peaks (P1 and P2), providing the P2/P1 ratio.Results: Fourteen patients aged from 26 to 73 years old met the inclusion criteria. Hydrocephalus etiologies were normal pressure hydrocephalus, post-traumatic and all patients had an abnormal intracranial compliance waveform, with P2 > P1 before the procedure (5 external ventricular drains (EVD) and 9 ventriculoperitoneal shunts (VPS). Immediately after, 75% of the patients changed to a standard pattern with P1 > P2.Conclusion: In this exploratory study using a novel noninvasive technique, rapid cerebrospinal fluid drainage by means of EVD and VPS was effectively assessed and had a positive impact on intracranial compliance.","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"157-163"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0