Turkish neurosurgery最新文献

{"title":"The Anterior Endoscopic Transcervical Approach: A Cadaveric Study on Anatomical Challenges and Surgical Limitations in Odontoidectomy.","authors":"Odhan Yuksel, Seckin Aydin, Aysegul Esen Aydin, Galip Zihni Sanus","doi":"10.5137/1019-5149.JTN.48438-25.2","DOIUrl":"10.5137/1019-5149.JTN.48438-25.2","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the anatomical characteristics, procedural constraints, and technical details of anterior endoscopic transcervical approach (AETCA) through cadaveric dissection.</p><p><strong>Material and methods: </strong>Nine human cadaver heads, transected at the C6-C7 level and preserved in 10% formalin for no less than 4 weeks, were utilized. A 0° endoscope and surgical drills were used for odontoid removal. The resection extent was determined through volumetric analysis using CT scans performed before and after the procedure. Fluoroscopy was employed for orientation, and volumetric measurements were used to assess the resection outcomes.</p><p><strong>Results: </strong>Across the specimens, the average resection rate of the dens was 54%. Complete removal was achieved in two cases, subtotal in another two, and partial in five. The use of angled drills yielded significantly greater resection compared to flat-ended variants. No significant vascular or neurological injuries were noted. In seven cases, the resection extended to the odontoid's posterior wall. Challenges included the narrow and elongated operative corridor and difficulty maintaining midline orientation; however, these were addressed with the assistance of a custom-designed tubular trocar.</p><p><strong>Conclusion: </strong>AETCA offers notable benefits, such as reduced risk of postoperative infections, shorter hospitalization, and decreased morbidity and healthcare expenditure. The study underscores the importance of technical expertise and enhanced instrumentation in achieving successful outcomes, particularly for complete odontoid removal while preserving adjacent anatomy. AETCA emerges as a viable and safer alternative for odontoidectomy, enhancing procedural efficiency. These findings contribute to the understanding of anatomical and technical factors relevant to the approach, supporting its clinical adoption and potentially shortening the learning curve.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"145-150"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146000346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In Memory of Dr. Zeki Oral.","authors":"Ilhan Elmaci","doi":"10.5137/1019-5149.JTN.49720-25.2","DOIUrl":"10.5137/1019-5149.JTN.49720-25.2","url":null,"abstract":"<p><p>Dr. Zeki Oral was born in Anamur in 1940. He completed his primary and secondary education in Anamur and his high school education in Bursa. In 1966, he graduated from Istanbul Faculty of Medicine and, in the same year, began his neurosurgery residency at Hacettepe Faculty of Medicine. Following his residency, he completed his military service at Kasımpaşa Naval Hospital, where he subsequently continued to work as a specialist physician. He then began his first post-residency instructor position at Taksim Training Hospital. With the enactment of the full-time practice law, he resigned from public service. After working for a period as a private practitioner, he accepted an invitation to serve as Chief of Neurosurgery Department at Bakırköy Mental and Neurological Diseases Hospital. After twenty years in this role, he decided to retire in 2012. He passed away on March 4, 2025.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 3","pages":"489"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148145804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Presentation to Publication: Publication Rates of Abstracts Presented at the Meetings of Two Neurosurgical Societies in Türkiye.","authors":"Emmanuel Mouladje Tchuela, Ismail Ertan Sevin, Selin Bozdag, Hasan Kamil Sucu","doi":"10.5137/1019-5149.JTN.48850-25.2","DOIUrl":"10.5137/1019-5149.JTN.48850-25.2","url":null,"abstract":"<p><strong>Aim: </strong>To assess the overall trends in scientific dissemination at neurosurgery meetings organized by the Turkish Neurosurgical Society (TNS) and the Society of Surgery of the Nervous System (SSNS), two major neurosurgical societies in Turkey.</p><p><strong>Material and methods: </strong>We reviewed 2,696 abstracts presented at TNS and SSNS annual meetings (2018?2022) and identified subsequent full-text publications through PubMed and Google Scholar. Data collected included presentation type, neurosurgical subspecialty, journal indexing, impact factor, and time to publication.</p><p><strong>Results: </strong>Of 2,696 abstracts, 323 (11.98%) were published as full-text articles, with a median time to publication of 11 months. Oral presentations had a significantly higher publication rate than poster presentations (20.8% vs 5.9%, p < 0.001). Award-winning abstracts showed a higher publication rate (73.08%, p < 0.001). Most publications appeared in SCIE-indexed journals (59.9%). No significant differences were found between TNS and SSNS in terms of publication rate (p=0.419) or time to publication (p=0.806). Rates varied by subspecialty, highest in surgical neuroanatomy (30.3%), and pediatric neurosurgery (15.5%), and lowest in spinal (8.7%) and neuro-oncology (8.5%) (p < 0.001).</p><p><strong>Conclusion: </strong>Although overall publication rates remain modest, oral presentations, award-winning abstracts, and certain subspecialties showed higher conversion to full-text publication. Initiatives such as structured mentorship, multi-center collaboration, and editorial support may enhance dissemination and publication success.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"211-217"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transnasal Transsphenoidal versus Transcranial Surgery for Resection of Sellar Lesions; A National Database Analysis.","authors":"Daniel N Munger, Brannan E O Neill, Ali I Rae, Mathew N Geltzeiler, Olabisi R Sanusi","doi":"10.5137/1019-5149.JTN.48023-24.1","DOIUrl":"10.5137/1019-5149.JTN.48023-24.1","url":null,"abstract":"<p><strong>Aim: </strong>To present a national database analysis comparing transnasal transsphenoidal (TNTS) and transcranial (TC) approaches in sellar lesion management.</p><p><strong>Material and methods: </strong>We analyzed the National Surgical Quality Improvement Program (NSQIP) database by TNTS and TC CPT codes from 2014-2018. Outcome measures included periprocedural complications, surgical complications, reoperation within 30 days, readmission, and death. Statistical comparisons were made using Wilcoxon rank-sum test in STATA.</p><p><strong>Results: </strong>A total of 488 procedures were identified (232 TC; 256 TNTS). Baseline demographics were comparable between groups. Patients undergoing craniotomy were more likely to have DVT or PE (8 vs 2 patients, p=0.042) and stroke (11 vs 0 patients, p < 0.001). TC approach was associated with longer hospital length-of-stay (6.1 vs 4.2 days, p < 0.001), 30-day readmission (15.8% vs 7.1%), and death (2.6% vs 0.4%, p=0.042). Craniotomy was more likely to be performed in nonelective cases (26.3% vs 12.6%, p < 0.001), however the difference in complication rates was driven by elective cases.</p><p><strong>Conclusion: </strong>We found that the TC approach to the sella was associated with higher rates of complications and greater mortality than the TNTS approach. The TC approach was also more likely to be performed in nonelective cases, but the difference in morbidity and mortality was driven by elective cases. Further study is warranted to identify lesion characteristics that may influence choice of approach and outcomes.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"316-320"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complications of Biportal Endoscopic Surgery for Lumbar Pathologies: Retrospective Analysis of 374 Cases.","authors":"Mehmet Ilker Ozer, Oguz Kagan Demirtas, Goktug Ulku, Mehmet Can Ezgu, Ilker Solmaz","doi":"10.5137/1019-5149.JTN.48431-25.3","DOIUrl":"10.5137/1019-5149.JTN.48431-25.3","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the complications associated with Unilateral Biportal Endoscopy (UBE) in spinal surgery, highlighting the risks and outcomes of this minimally invasive approach.</p><p><strong>Material and methods: </strong>A retrospective analysis was conducted on 374 patients who underwent UBE at three centers from 2022 to 2023. The study included cases of lumbar disc herniation, recurrent disc herniation, and lumbar stenosis. All procedures were performed by experienced surgeons, with a minimum postoperative follow-up of one year for each patient.</p><p><strong>Results: </strong>A total of 374 patients were included: 224 underwent UBE discectomy, 115 underwent UBE decompression for lumbar stenosis, and 35 underwent surgery for recurrent herniation. Overall, 178 patients (47.5%) were female and 196 (52.4%) were male. Complication rates differed across cohorts: 19 complications occurred in primary discectomy cases (8.4%), 12 in stenosis cases (10.4%), and 5 in recurrent cases (14.2%). The most common complications were dural tear (n=8), recurrence (n=7), and root injury (n=6). Less frequent events included retinal hemorrhage (n=2) and hydroperitoneum (n=1).</p><p><strong>Conclusion: </strong>The findings suggest that while UBE is generally safe, it is associated with a notable complication rate, including dural tears and root injuries. Continuous efforts to refine surgical techniques and enhance training may further mitigate these risks, ensuring better patient outcomes.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":" ","pages":"237-245"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147358401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diffusion Tensor Imaging Metrics Reveal Pronounced Hemispheric Asymmetry in Major White Matter Tracts.","authors":"Taghi Khaniyev, Efecan Cekic, Muhammed Yakup Altug, Egemen Gok, Sema Nur Kibrit, Bayazit Kayaoglu, Merve Pinar, Sahin Hanalioglu","doi":"10.5137/1019-5149.JTN.50630-26.5","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.50630-26.5","url":null,"abstract":"<p><strong>Abstract: </strong>AIM: To determine hemispheric asymmetries in major white matter tracts using diffusion tensor imaging (DTI) metrics and morphometric measurements, as comprehensive multitract analyses remain limited. MATERIAL and METHODS: Diffusion MRI data from 102 healthy adults enrolled in the Human Connectome Project (HCP) were analyzed using DSI Studio to reconstruct 17 major white- matter tracts bilaterally. For each tract, diffusion metrics (fractional anisotropy [FA], mean diffusivity [MD], radial diffusivity [RD], axial diffusivity [AD], quantitative anisotropy [QA], isotropic value [ISO], restricted diffusion imaging [RDI], and normalized RDI [nrdı]) and morphometric parameters (fiber count, mean length, trunk volume, branch volume, total volume, and termination region areas) were quantified. Paired t-tests compared left-right hemispheric differences. Multiple comparison corrections were performed with the Benjamini-Krieger-Yekutieli procedure, and effect sizes were reported as Cohen's d. RESULTS: Significant hemispheric asymmetries were observed in most tracts. FA was significantly higher in the left hemisphere (p<0.001) for the arcuate fasciculus (AF), inferior fronto-occipital fasciculus (IFOF), inferior longitudinal fasciculus (ILF), and uncinate fasciculus (UF). Mean diffusivity (MD) demonstrated left dominance in the UF and SLF2-3 (p=0.009). QA was predominantly left- lateralized across multiple tracts, including AF, IFOF, ILF, and frontal aslant tract (FAT) (p<0.01, Cohen's d: 0.42 to 1.17), except for the vertical occipital fasciculus (VOF), where rightward dominance was noted (Cohen's d: -0.55). Tract-trunk-branch volumes were predominantly left-lateralized in frontal lobe pathways such as AF, SLF1, SLF2, FAT, and UF (p<0.01). Rightward dominance was observed in SLF3, parietal aslant tract (PAT), IFOF, ILF, and middle longitudinal fasciculus (MLF) (p<0.05). Similar asymmetries were observed in termination region areas, fiber counts, and fiber lengths (p<0.001). CONCLUSION: Widespread hemispheric asymmetries were observed across multiple pathways. Such asymmetry may reflect distinct hemispheric functional specialization and the neurological basis of lateralized functions.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 4","pages":"587-607"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148655280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gamma Knife Radiosurgery-Induced Acute Facial Palsy in Vestibular Schwannoma: A Case Report.","authors":"Osman Burak Can, Mete Ruksen","doi":"10.5137/1019-5149.JTN.49629-25.2","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.49629-25.2","url":null,"abstract":"<p><strong>Abstract: </strong>Stereotactic radiosurgery (SRS) is an established treatment for vestibular schwannoma, offering high tumor control rates and a favorable safety profile. SRS-induced facial palsy is typically a late-onset complication, with acute-onset cases being exceedingly rare. We report the case of a 42-year-old man with a left-sided Koos grade I vestibular schwannoma who underwent single-fraction Gamma Knife radiosurgery with a prescription dose of 11 Gy to the 50% isodose line. Baseline facial nerve function was intact. Seventy-two hours post-treatment, the patient developed House-Brackmann (HB) grade V peripheral facial palsy, accompanied by severe vestibular symptoms. Magnetic resonance imaging obtained on post-treatment day 6 demonstrated reduced contrast enhancement, partial capsular breakdown, and central hypointensity within the tumor, suggestive of acute necrotic change. Vestibular symptoms improved rapidly following corticosteroid therapy; however, facial palsy recovery was gradual, improving to HB grade II at 12 months, with persistence at final follow-up (20 months). The tumor remained radiologically stable. Acute-onset facial palsy following SRS for vestibular schwannoma is extremely rare, with only four previous cases reported in the literature. This is the first reported case to occur following a relatively low margin dose-11 Gy-in contrast to the 13-14 Gy doses prescribed in earlier reports.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 4","pages":"620-623"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148655561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Sodium Nitrite on Neural Tube Development in Early-Stage Chick Embryos.","authors":"Ezgi Akar, Eylem Burcu Kahraman Ozlu, Dila Sener Akcora, Dilek Akakin, Selin Tural","doi":"10.5137/1019-5149.JTN.49993-25.2","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.49993-25.2","url":null,"abstract":"<p><strong>Abstract: </strong>AIM: To investigate the effects of sodium nitrite on spinal cord development in early-stage chick embryos. MATERIAL and METHODS: Sixty specific-pathogen-free fertile Leghorn-type eggs at Day 0 of incubation were used. Group 1 (control) received saline, Group 2 (low-dose) was administered 0.0042 mg of sodium nitrite, and Group 3 (high-dose) received 0.0084 mg. Embryonic disks were microscopically examined after 72 hours of incubation. RESULTS: In the control group, the surface ectoderm was intact, the neural tube was properly closed, and the neuroepithelium, basement membrane, somites, and notochord exhibited normal morphology. Neural tube defects were identified in seven embryos in the low-dose group and nine embryos in the high-dose group. Statistical analysis revealed that both sodium nitrite-exposed groups exhibited a significantly higher incidence of neural tube defects compared with the control group (p < 0.05). However, no statistically significant difference was observed between the low- and high-dose groups. CONCLUSION: Exposure to low and high doses of sodium nitrite induced neural tube defects in chick embryos, suggesting potential embryotoxic effects.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 4","pages":"548-552"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148655571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Optic Nerve Sheath Diameter Cut-off after CSF Drainage in Adults with Elevated ICP: A Prospective Study.","authors":"Gulsah Ozkaya, Ozlem Korkmaz Dilmen, Eren Fatma Akcil, Yusuf Tunali","doi":"10.5137/1019-5149.JTN.49051-25.4","DOIUrl":"10.5137/1019-5149.JTN.49051-25.4","url":null,"abstract":"<p><strong>Abstract: </strong>AIM: To evaluate the relationship between optic nerve sheath diameter (ONSD) and intracranial pressure (ICP) in patients with acute ICP elevation controlled through external ventricular drainage (EVD). MATERIAL and METHODS: In this prospective observational study, simultaneous measurements of right and left ONSD, ICP, and cerebral perfusion pressure (CPP) were recorded in 46 adult patients undergoing EVD. Two patients were excluded due to ophthalmic pathology and missing data, resulting in a final cohort of N = 44 patients. After we obtained the baseline measurements, 5 mL of cerebrospinal fluid (CSF) were drained, and the measurements were repeated 2 minutes (min) later. RESULTS: CSF drainage led to significant reductions in both ICP and bilateral ONSD (p = .001 for all), while CPP significantly increased (p = .038). We identified an ONSD cut-off of 5.35 mm for detecting ICP values ≥15 mmHg, and this cut-off had 53% sensitivity and 86% specificity (Youden index: 0.395). However, we could not determine a reliable cut-off for detecting ICP values ≥20 mmHg (p = .076). CONCLUSION: When ICP is controlled through EVD, the linear relationship between ONSD and ICP observed during acute pressure elevations may be disrupted, particularly at higher ICP values (≥20 mmHg). Although we identified a cut-off ONSD value of 5.35 mm for detecting ICP values ≥15 mmHg, the low sensitivity of this cut-off significantly limits its clinical utility. Additionally, since no reliable cut-off could be established for ICP values ≥20 mmHg, ONSD may have limited value for monitoring pressure following CSF drainage.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 4","pages":"573-580"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148655531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Association of Modic Changes and Clinical Outcome Before and After One-Level Lumbar Fusion.","authors":"Filippo Mandelli, Victoria Schimmelpenning, Francesco Langella, Domenico Compagnone, Andrea Nervi, Andrea Redaelli, Daniele Vanni, Marco Damilano, Riccardo Cecchinato, Pedro Berjano","doi":"10.5137/1019-5149.JTN.49485-25.1","DOIUrl":"https://doi.org/10.5137/1019-5149.JTN.49485-25.1","url":null,"abstract":"<p><strong>Abstract: </strong>AIM: To assess the association between Modic changes (MCs) and clinical outcomes in patients undergoing one-level lumbar fusion surgery. MATERIAL and METHODS: A retrospective cohort study included patients (>18 years) with single-level DDD treated with one-level lumbar fusion from 2016 to 2020 at a single center. Preoperative and 2-year postoperative outcomes were collected, including the Visual Analog Scales (VAS-back and VAS-leg), Oswestry-Disability-Index (ODI), Core-Outcome-Measures-Index (COMI-back) and Short-Form-Health-Survey-36 (SF-36). The association of patient reported outcomes measurements (PROMs) with preoperative MCs on MRI were assessed. Subjects with MC2 and MC3 were pooled in the No-MC1 group and compared to MC1 group. Continuous variables were compared using independent or paired t-tests, and non-parametric data with Mann-Whitney U or Wilcoxon signed-rank tests. Categorical variables were analyzed with Chi-square or Fisher's exact test. RESULTS: Preoperatively, the MC1 group exhibited higher ODI scores (47.05±14.60 vs. 36.84±13.12; p=0.026) and lower SF-36-PCs (30.80±7.22 vs. 35.61±5.17; p=0.021) compared to the No-MC1 group. Postoperatively, no significant intergroup differences were observed. However, the MC1 group demonstrated greater improvements in ΔODI, ΔVAS-back, and ΔSF-36-PCs. Intragroup analysis revealed significant postoperative improvements in ODI, VAS-back, and VAS-leg in the MC1 group (e.g., ΔODI= 29.14±13.27; p= 0.007), while the No-MC1 group improved in ODI and SF-36-Mental Components (ΔODI= 21.10±12.26; p= 0.023; ΔSF-36-MCs= 5.98±12.44; p= 0.003). Notably, 7 patients did not reach the ΔODI minimum clinically important difference, with higher prevalence in the No-MC1 group (71.4%). CONCLUSION: One-level spinal fusion improves clinical outcomes in symptomatic degenerative disc disease. Patients with MC1 demonstrate greater functional and pain-related improvements compared to those with MC2 or MC3.</p>","PeriodicalId":94381,"journal":{"name":"Turkish neurosurgery","volume":"36 5","pages":"682-688"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149121036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}