Cardiology in the Young最新文献

{"title":"Staged repair for coarctation of the aorta with ventricular septal defect using stent angioplasty in an extremely low-birth-weight premature infant: a case report.","authors":"Toshi Maeda, Hiroki Ito, Keiichi Hirose","doi":"10.1017/S104795112510961X","DOIUrl":"https://doi.org/10.1017/S104795112510961X","url":null,"abstract":"<p><p>Primary intracardiac repair during the neonatal or early infantile period is challenging in low-birth-weight infants with coarctation of the aorta and a ventricular septal defect. We performed a staged repair in a 1020 g infant, beginning with stent angioplasty followed by surgical repair with direct anastomosis.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous closure of a large left main coronary artery fistula in a paediatric patient.","authors":"Manuela da Silva Lopes, Diogo Faim, Patrícia Vaz Silva, António Pires","doi":"10.1017/S1047951125109694","DOIUrl":"https://doi.org/10.1017/S1047951125109694","url":null,"abstract":"<p><p>A large left coronary artery fistula in a child was successfully closed percutaneously using an Amplatzer Vascular Plug II through an arteriovenous loop.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-2"},"PeriodicalIF":0.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145124302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Totally anomalous origin of the coronary arteries from the pulmonary trunk: a case report.","authors":"Carolina Vieira Campos, Ulisses Alexandre Croti, Vera Demarchi Aiello","doi":"10.1017/S1047951125109566","DOIUrl":"https://doi.org/10.1017/S1047951125109566","url":null,"abstract":"<p><p>Coronary anomalies are a rare but potentially fatal congenital defect. Among high-risk anatomic features, totally anomalous origin of the coronary arteries from the pulmonary trunk is extremely rare, with only 57 cases reported in the literature as to our knowledge. We report a case of such a congenital anomaly with a successful surgical repair and good cardiac function recovery. We emphasise the need for awareness, since this anatomic presentation precludes collateral development and has, therefore, a higher mortality rate.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ascending-to-descending aortic grafting: an alternative approach for adults with complex aortic coarctation.","authors":"Polona Kacar, Giulia Iannaccone, Pietro Paolo Tamborrino, Darryl Shore, Michael Murphy, Ulrich Rosendahl, Michael A Gatzoulis, Claudia Montanaro","doi":"10.1017/S104795112510958X","DOIUrl":"https://doi.org/10.1017/S104795112510958X","url":null,"abstract":"<p><strong>Objective: </strong>Contemporary management of aortic coarctation in adults is primarily by percutaneous intervention; however, this is not always possible. Intrapericardial ascending-to-descending aortic grafting is an alternative approach in adults with complex aortic coarctation. It can be performed off-pump and allows for a simultaneous treatment of concomitant cardiac lesions. Our aim was to examine the indications and the clinical long-term outcomes of intrapericardial ascending-to-descending aortic grafting in adults with aortic coarctation.</p><p><strong>Methods: </strong>We retrospectively reviewed demographic, clinical, surgical, and follow-up data of patients who underwent intrapericardial ascending-to-descending aortic grafting at a single tertiary centre between September 1994 and November 2016.</p><p><strong>Results: </strong>Ten patients were identified. Indications were primary intervention (<i>n</i> = 4), re-coarctation (<i>n</i> = 5), and iatrogenic coarctation of aorta after stent grafting (<i>n</i> = 1). There were no peri-operative deaths. During a mean follow-up of 13.6 ± 9.4 years, one patient died 11 years after surgery, unrelated to intrapericardial ascending-to-descending aortic grafting. All grafts remained patent with no anastomotic pseudoaneurysms at latest follow-up.The mean systolic blood pressure decreased from 154 ± 24 mmHg at baseline to 134 ± 20 mmHg at latest follow-up (<i>p</i> = 0.05), with the mean number of prescribed antihypertensive medications decreasing from 2.8 ± 1.5 preoperatively to 1.6 ± 0.5 (<i>p</i> = 0.11).</p><p><strong>Conclusion: </strong>Intrapericardial ascending-to-descending aortic grafting is a safe and effective approach for adults with complex coarctation of aorta or re-coarctation not suitable for a percutaneous or conventional surgical approach. Improved blood pressure control and reduced anti-hypertensive use were observed long-term.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145111980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased utilisation of analgesia and sedation in patients following bidirectional Glenn: evidence for the \"Glenn Headache\"?","authors":"Laura Hermann, Matthew Coghill, Lindsey Justice, David S Cooper, Brendan Thomas Homanick, Christin Diller, Maria H Santos de Oliveria, Brandon Henry, David Lehenbauer, Amy Ryan Florez","doi":"10.1017/S1047951125109487","DOIUrl":"https://doi.org/10.1017/S1047951125109487","url":null,"abstract":"<p><strong>Background: </strong>Single ventricle patients undergoing bidirectional Glenn palliation subjectively experience increased post-operative agitation and discomfort. This is presumed to be secondary to increased intracranial pressure due to physiologic changes. This state of discomfort has been dubbed the \"Glenn headache.\" The purpose of this study was to determine whether sedation and analgesia requirements were higher in post-operative bidirectional Glenn patients than those of similar age who undergo tetralogy of Fallot or ventricular septal defect repairs.</p><p><strong>Methods: </strong>Retrospective chart review was performed. Medication use, demographic, and haemodynamic data were collected. Comparisons between all groups were performed using the chi-squared test, Fisher's exact test, Kruskal-Wallis test, and Dunn test.</p><p><strong>Results: </strong>A total of 96 patients met inclusion criteria. Thirty-nine patients (40.3%) underwent bidirectional Glenn, 36 patients (37.5%) tetralogy of Fallot repair, and 21 patients (21.9%) ventricular septal defect closure. When comparing as needed (PRN) morphine, lorazepam, and oxycodone boluses between the three groups, patients who underwent bidirectional Glenn received significantly more doses in comparison with the other two groups (all <i>p</i> < 0.001). The total dose of morphine (<i>p</i> = 0.001) and dexmedetomidine infusions (<i>p</i> < 0.001) were also higher in the bidirectional Glenn group than in ventricular septal defect patients, but equivalent to tetralogy of Fallot patients. There was no significant difference in post-operative intubation status or total hours of mechanical ventilation when comparing bidirectional Glenn patients to those who underwent both tetralogy of Fallot and ventricular septal defect repairs.</p><p><strong>Conclusions: </strong>Study demonstrates that patients who undergo bidirectional Glenn have higher analgesic and sedation requirements than similar aged patients who undergo tetralogy of Fallot or ventricular septal defect repairs.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platypnea-Orthodeoxia syndrome following stent implantation into the Fontan tunnel.","authors":"Natalia Nawara-Węgrzyn, Aleksandra Dziewulska, Sebastian Góreczny","doi":"10.1017/S1047951125101108","DOIUrl":"https://doi.org/10.1017/S1047951125101108","url":null,"abstract":"<p><p>Fontan conduit stenosis can impair haemodynamics, necessitating stent implantation. We present a 16-year-old patient who developed platypnea-orthodeoxia syndrome due to a post-stenting baffle leak. Despite initial diagnostic challenges, a second catheterisation confirmed and successfully sealed the defect with a covered stent. This case highlights the need for close monitoring and prompt intervention to manage complications in Fontan patients.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A randomised clinical trial of regional cerebral perfusion versus deep hypothermic circulatory arrest: five-year and ten-year follow-up for neurodevelopmental outcomes in children with functional single ventricle.","authors":"Robin Mark Wolschendorf, Melissa Smith-Parrish, Amalia Peterson, Sunkyung Yu, Richard G Ohye, Edward Bove, Mary Best, Caren S Goldberg","doi":"10.1017/S1047951125100541","DOIUrl":"https://doi.org/10.1017/S1047951125100541","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate school-age neurodevelopmental outcomes among children with single ventricle heart disease who underwent neonatal Norwood operation with regional cerebral perfusion compared to deep hypothermic circulatory arrest. Additionally, we aimed to identify predictors of school-age development, including early developmental measures.</p><p><strong>Study design: </strong>Patients enrolled in a prospective randomised trial of infants with single ventricle heart disease undergoing the Norwood operation with either regional cerebral perfusion or deep hypothermic circulatory arrest were included. For the same cohort of patients, this study performed neurodevelopmental testing at 5 years and 10 years of age. At 5 years, a comprehensive neuropsychological evaluation was performed. At 10 years, parent report instruments were used to measure participants' behaviour and executive function.</p><p><strong>Results: </strong>Forty-one patients at 5 years of age and 33 patients at 10 years of age completed neurodevelopmental evaluation. There were no significant differences in neurodevelopmental scores between the regional cerebral perfusion and deep hypothermic circulatory arrest groups at either 5 or 10 years. At 5 years of age, the average full scale intelligence quotient (IQ) was 93.4 ± SD18.8. The Bayley Scale of Infant Development Psychomotor Developmental Index (<i>r</i> = 0.68, <i>p</i> < .0001) and mental developmental index (<i>r</i> = 0.64, <i>p</i> < .0001) at 1 year positively correlated with the full scale IQ at 5 years.</p><p><strong>Conclusions: </strong>Neurodevelopment is delayed in patients with single ventricle heart disease. Neurodevelopmental outcomes at school age did not differ based on the perfusion strategy for the Norwood operation. Mental and psychomotor developmental indices at 1 year are predictive of early school-age measures.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-7"},"PeriodicalIF":0.7,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145079695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of epicardial adipose tissue as a marker in cardiac involvement in childhood primary hypertension.","authors":"Özgür Özdemir Şimşek, Yeliz Sevinç, Ahmet Keskinoğlu, Pembe Keskinoğlu","doi":"10.1017/S1047951125109554","DOIUrl":"https://doi.org/10.1017/S1047951125109554","url":null,"abstract":"<p><strong>Background: </strong>Patients diagnosed with hypertension (HT) are at high risk for end-organ damage. With changing living conditions and access to healthcare facilities worldwide, the rate of diagnosis in childhood is increasing. In this study, healthy children were compared with a group of pediatric patients diagnosed with hypertension. Cardiac findings in the hypertensive group were compared at presentation and at six months. We aimed to determine the discriminatory value of epicardial adipose tissue (EAT) measurements as an early imaging marker for cardiac involvement in children with HT compared to healthy children and to determine its prognostic feature for HT treatment response.</p><p><strong>Methods: </strong>Fifty-nine primary hypertension patients and 76 control patients aged 0-18 years were compared. EAT values measured between the healthy group and the patient group and at the beginning of treatment and subsequent follow-ups in the patient group were evaluated with M-mode measurements.</p><p><strong>Results: </strong>There was no difference between the groups in terms of sex, and age. EAT was found to be significantly higher in the patient group than in the healthy group. There was a statistically significant difference between the EAT measurements evaluated before and after treatment in the patient group.</p><p><strong>Conclusions: </strong>Hypertension is an important cause of morbidity and mortality. Using EAT measurements as a noninvasive parameter may provide information about early cardiac involvement due to HT. EAT is promising as an imaging marker that can be used in diagnosis and follow-up.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-7"},"PeriodicalIF":0.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of fetal cardiac intervention for prenatal complex CHD.","authors":"Zhangwei Wang, Honghao Fu, Shoujun Li","doi":"10.1017/S1047951125109451","DOIUrl":"https://doi.org/10.1017/S1047951125109451","url":null,"abstract":"<p><p>Over the past 30 years, with the development of diagnostic and therapeutic techniques and the formation of multidisciplinary teams, the safety and efficacy of fetal cardiac intervention (FCI) have been increasingly recognised by fetal medicine and fetal cardiologists, and it has been carried out in many children's heart centres around the world. More and more evidence shows that FCI can optimise ventricular haemodynamics, prevent ventricular dysplasia, promote the establishment of biventricular circulation, help alleviate or change the course of the disease, and can be used as a treatment method to save ventricular and great vessel development. This article reviews the history and current status, mechanism of action, surgical indications, and clinical outcomes of FCI for treating CHD in fetuses. It also analyses the development opportunities and challenges of FCI and proposes constructive suggestions for future research directions and improvement measures, with the aim of providing a reference basis for the in-depth development of this field.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-7"},"PeriodicalIF":0.7,"publicationDate":"2025-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric scoring systems in congenital heart surgery: evaluating predictive accuracy for major adverse events.","authors":"Seyma Sayit Akyar, Nurgul Yurtseven, Ozgecan Pırıl Zanbak Mutlu, Deniz Mutlu, Osman Ekinci","doi":"10.1017/S1047951125109517","DOIUrl":"https://doi.org/10.1017/S1047951125109517","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the predictive accuracy of Paediatric Risk of Mortality-III, Paediatric Index of Mortality-II, and Paediatric Logistic Organ Dysfunction scoring systems for major adverse events following congenital heart surgery.</p><p><strong>Methods: </strong>This prospective observational study included patients under 18 years of age who were admitted to the ICU for at least 24 hours postoperatively following congenital heart surgery. Major adverse events were defined as a composite of 30-day mortality, ICU readmission, reintubation, acute neurologic events, requirement for extracorporeal membrane oxygenation, cardiac arrest requiring cardiopulmonary resuscitation, need for a permanent pacemaker, acute kidney injury, or unplanned reoperation.</p><p><strong>Results: </strong>A total of 116 patients, with a median age of 17.5 months (interquartile range: 5.4-60.0) were included in the study. Major adverse events occurred in 34 patients (29.3%). Paediatric Risk of Mortality-III (11.5 [8.0-18.8] vs. 7.0 [2.3-11.0]; <i>p</i> = 0.001), Paediatric Index of Mortality-II (3.8 [2.8-6.6] vs. 2.2 [1.7-2.8]; <i>p</i> < 0.001), and Paediatric Logistic Organ Dysfunction (12.0 [10.0-21.0] vs. 1.0 [1.0-10.0]; <i>p</i> < 0.001) scores were significantly higher in patients with major adverse events than in those without. The Paediatric Logistic Organ Dysfunction score (area under the curve 0.83; 95% confidence interval: 0.74-0.92) demonstrated the highest discrimination capacity compared to Paediatric Risk of Mortality-III (area under the curve 0.70; 95% confidence interval: 0.60-0.81) and Paediatric Index of Mortality-II (area under the curve 0.77; 95% confidence interval: 0.66-0.88) with good calibration (Hosmer-Lemeshow <i>p</i> > 0.05 for all). Based on the logistic regression model evaluation metrics, Paediatric Logistic Organ Dysfunction demonstrated better performance in predicting major adverse events compared with Paediatric Risk of Mortality-III and Paediatric Index of Mortality-II.</p><p><strong>Conclusions: </strong>The Paediatric Logistic Organ Dysfunction score outperformed the Paediatric Index of Mortality-II and Paediatric Risk of Mortality-III scores in predicting major adverse events in paediatric patients admitted to the ICU after congenital heart surgery.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-7"},"PeriodicalIF":0.7,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145032808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}