Cardiology in the Young最新文献

{"title":"Thoracic endovascular aortic repair for high-risk Stanford type B aortic dissection in a 15-year-old patient with genetic mutations: a case report with follow-up of four years.","authors":"Xu-Xian Qiu, Yi-Peng Hu, Dong-Lin Li","doi":"10.1017/S1047951126112025","DOIUrl":"https://doi.org/10.1017/S1047951126112025","url":null,"abstract":"<p><p>This case report presents mid- to long-term outcomes of thoracic endovascular aortic repair for high-risk type B aortic dissection in a 15-year-old patient with myosin heavy chain protein 11 genetic mutations. A CT scan showed the primary entry tear located on the lesser curvature near the left subclavian artery, and the dissection originated from the descending aorta to the abdominal aorta, accompanied by 80% narrowing of the true lumen. Following successful endovascular therapy using stent-grafts, the patient recovered well. A four-year follow-up CT scan showed significant thoracic aorta remodelling.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-4"},"PeriodicalIF":0.7,"publicationDate":"2026-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Larger lung volumes in fetuses with transposition of the great arteries and an intact ventricular septum compared to heart healthy fetuses and fetuses with transposition of the great arteries and a ventricular septal defect.","authors":"Emil Krogh, Signe Gade Hellmuth, Ditte Staub Jørgensen, Benjamin Kelly, Niels Vejlstrup, Olav Petersen, Vibeke E Hjortdal, Mette H Lauridsen","doi":"10.1017/S1047951126112281","DOIUrl":"https://doi.org/10.1017/S1047951126112281","url":null,"abstract":"<p><strong>Background: </strong>Complex CHDs may impair organ development. One proposed mechanism is an altered relationship between blood flow, oxygen delivery, and subsequent organ growth. In this study, we examined whether fetal lung, intracranial, liver, and kidney volumes differ among fetuses with transposition of the great arteries with an intact ventricular septum, transposition of the great arteries with a ventricular septal defect, and healthy controls.</p><p><strong>Methods: </strong>Eleven fetuses with transposition of the great arteries (6 with a ventricular septal defect and 5 with an intact ventricular septum) and 22 healthy controls were scanned between 1 and 3 times at gestational age 27-38 weeks, using fetal MRI. We measured lung, total intracranial, liver, and kidney volumes and compared fetuses with and without transposition of the great arteries while subsequently correcting for ventricular septal defect/intact ventricular septum status, estimated fetal weight, and gestational age, using mixed effects regression analysis.</p><p><strong>Results: </strong>Fetuses with transposition of the great arteries+intact ventricular septum had significantly larger lung volumes compared to controls. After adjusting for estimated fetal weight and gestational age, median lung volume ratio (transposition of the great arteries+intact ventricular septum vs. controls) was 1.30 (95% CI: 1.08-1.57; <i>p</i> = 0.005). No difference was found in lung volume between fetuses with transposition of the great arteries+ventricular septal defect and controls. No significant differences in total intracranial, liver, and kidney volumes were found between transposition of the great arteries+ventricular septal defect, transposition of the great arteries+intact ventricular septum, and controls.</p><p><strong>Conclusion: </strong>In this preliminary study, late-gestation fetuses with transposition of the great arteries-intact ventricular septum had a 30% larger lung volume compared with both transposition of the great arteries-ventricular septal defect and healthy controls. Together with existing evidence of higher fetal pulmonary blood flow and increased oxygen saturation in transposition of the great arteries-intact ventricular septum, these findings support a potential link between blood flow, oxygen delivery, and organ growth.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic evaluation of extracardiac findings on cardiac CT angiography in children with CHD: a large single-centre experience.","authors":"Halise Zeynep Genc, Ali Nazim Guzelbag, Demet Kangel, Elnur Karimov, Ezgi Direnc Yucel, Ali Can Hatemi, Erkut Ozturk, Serap Bas","doi":"10.1017/S1047951126112955","DOIUrl":"https://doi.org/10.1017/S1047951126112955","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiac CT angiography has seen a steady increase in use for the evaluation of CHD in children. While its primary role is to assess cardiovascular structures, CT angiography also captures extracardiac regions, often revealing previously unsuspected abnormalities. This study sought to determine the prevalence, classification, and clinical relevance of extracardiac abnormalities detected in paediatric patients undergoing CT angiography for CHD evaluation.</p><p><strong>Materials and methods: </strong>A retrospective review was conducted on CT angiography examinations from 1336 patients, aged from newborn to 17 years, at a single tertiary care institution. Extracardiac findings within the thoracic and abdominal regions were systematically identified, categorised, and analysed statistically.</p><p><strong>Results: </strong>Extracardiac abnormalities were common, predominantly affecting the respiratory system, including pneumonia (14.5%), atelectasis (13.3%), and pulmonary oedema (11.5%). Airway changes included bronchial malposition (23.3%) and peribronchial thickening (8.3%). Abdominal anomalies were also detected, the most common being hepatomegaly (13.1%), splenomegaly (6.9%), and horseshoe kidney (5.7%). Several of these findings were clinically important and had the potential to affect patient management.</p><p><strong>Discussion: </strong>Extracardiac anomalies are a common finding in paediatric CT angiography performed for CHD evaluation and can have significant clinical consequences. Radiologists and clinicians should follow a systematic approach that evaluates both cardiovascular and extracardiac structures to improve diagnostic accuracy and optimise patient care. In addition to common thoracic and abdominal abnormalities, CT angiography enabled the identification of rare and complex extracardiac anatomical patterns, underscoring its value as a comprehensive imaging modality in paediatric CHD.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-8"},"PeriodicalIF":0.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Six-hour renal resistive index as an early marker of acute kidney injury after infant cardiac surgery: a prospective cohort study.","authors":"Ahmed R Elsaoudi, Yasser Kazzaz, Sameh Rabie Ismail, Abdulraouf M Z Jijeh, Ghassan A Shaath, Hayan Altaweel, Omar Hijazi, Ammar M H Qadi, Mohamed S Kabbani, Hussam K Hamadah","doi":"10.1017/S1047951126112219","DOIUrl":"https://doi.org/10.1017/S1047951126112219","url":null,"abstract":"<p><strong>Background: </strong>Acute kidney injury after infant congenital cardiac surgery is common and worsens outcomes. Renal resistive index may aid early postoperative risk stratification.</p><p><strong>Objective: </strong>To evaluate a single six-hour postoperative renal resistive index as an early acute kidney injury marker and its association with postoperative haemodynamic support.</p><p><strong>Methods: </strong>A prospective single-centre cohort of neonates and infants < 12 months (<i>n</i> = 41) was classified as acute kidney injury (<i>n</i> = 19) or non-acute kidney injury (<i>n</i> = 22). Renal resistive index was measured at six hours (primary), 48 hr, and discharge. Postoperative acute kidney injury was diagnosed using Kidney Disease: Improving Global Outcomes serum creatinine and urine output criteria over 48 hr. Vasoactive-inotropic score was recorded, and discrimination was assessed using receiver operating characteristic analysis.</p><p><strong>Results: </strong>At six hours, renal resistive index was higher in acute kidney injury vs. non-acute kidney injury (0.84 ± 0.07 vs. 0.74 ± 0.08; <i>p</i> = 0.0002) with good unadjusted discrimination (area under the curve 0.83; 95% CI 0.68-0.97). Surgical complexity was higher in the acute kidney injury group (median STAT 4 vs. 3). At 48 hr, renal resistive index remained higher (<i>p</i> = 0.017; area under the curve 0.70), while discharge values were similar (<i>p</i> = 0.18; area under the curve 0.62). A six-hour renal resistive index < 0.80 excluded moderate-to-severe acute kidney injury, whereas ≥ 0.86 identified a higher risk. Vasoactive-inotropic score at 48 hr was higher in acute kidney injury (7.2 ± 8.1 vs. 1.9 ± 3.4; <i>p</i> = 0.009), and six-hour renal resistive index correlated modestly with inotropic burden (<i>r</i> = 0.56; <i>p</i> < 0.001). Three acute kidney injury infants required peritoneal dialysis, all with six-hour renal resistive index ≥ 0.90.</p><p><strong>Conclusions: </strong>A six-hour renal resistive index may help early acute kidney injury risk assessment after infant cardiac surgery. External validation is warranted.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Double trouble: double aortic arch with bilateral interruption and bilateral arterial ducts.","authors":"Karim Salhadar, Stephen M Langley, Daniel McKenna, Robert H Anderson, Deepa Prasad","doi":"10.1017/S1047951126113006","DOIUrl":"https://doi.org/10.1017/S1047951126113006","url":null,"abstract":"<p><p>Double aortic arch with bilateral interruptions is a rare abnormality. Indeed, to the best of our knowledge, it has not previously been reported before. Rare variants, such as a double arch with ligamentous atresia of the left component and double arch with bilateral coarctation, have received previous attention. These rare examples can pose significant diagnostic challenges for those relying on transthoracic echocardiography. Use of cardiac CT or MRI is now critical for prompt surgical planning and correction.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Navigating downtime as a cardiac data abstractor: ensuring data quality and registry submission.","authors":"Sarah Schukei, Kelli Shores, Marian Morris, Dristi Khanal, Andrew Well, Jeremy T Affolter, Elizabeth McCullum, Constantine David Mavroudis","doi":"10.1017/S104795112611213X","DOIUrl":"https://doi.org/10.1017/S104795112611213X","url":null,"abstract":"<p><strong>Introduction: </strong>Electronic medical records (EMRs) have become foundational to healthcare, improving communication, data access, and patient outcomes. However, increasing reliance on EMR's has increased vulnerabitlity during downtime. In paediatric cardiac care, where patients require highly specialized, multidisciplinary treatment, the absence of a functional EMR significantly disrupts documentation workflows and threatens the accuracy of data submitted to national cardiac registries including the Paediatric Cardiac Critical Care Consortium and the Society of Thoracic Surgeons.</p><p><strong>Methods: </strong>This article examines the impact of an unexpected 27-day complete EMR downtime followed by a 10-day partial downtime, where a data abstraction team manually managed data for 123 unique cardiac patient encounters totalling 762 patient days at a paediatric heart centre and the response of the cardiac data abstraction team. We describe how the team adapted its abstraction process during the downtime, used collaborative strategies, enhanced paper tracking, and proactively communicated to maintain data integrity. Efforts were grounded in a deep understanding of paediatric registry metrics and submission requirements.</p><p><strong>Results: </strong>Despite significant workflow disruptions, the team was able to preserve data accuracy and meet registry deadlines by identifying documentation gaps, supplementing data from paper records, and coordinating with frontline providers. The event revealed key vulnerabilities in downtime preparedness but also demonstrated the value of dedicated data abstractors in ensuring continuity of quality reporting.</p><p><strong>Conclusion: </strong>Downtime events highlight the critical role of data abstractors and the need for institutional planning and registry-level guidance. Developing robust downtime protocols and embedding abstraction-aware workflows can mitigate documentation risks and protect data quality, ultimately supporting improved outcomes for paediatric cardiac patients.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postnatal manifestation of left heart failure following foetal-onset right heart failure in biventricular noncompaction with an <i>MYH7</i> variant: a case report.","authors":"Yuya Yamada, Keiichi Hirono, Kazushi Yasuda","doi":"10.1017/S1047951126112980","DOIUrl":"https://doi.org/10.1017/S1047951126112980","url":null,"abstract":"<p><p>We report a case of foetal-onset biventricular noncompaction with an <i>MYH7</i> variant. Prenatal fetal hydrops and right heart failure resolved after birth, but progressive left heart failure developed at 5 months. This transition reflects how postnatal hemodynamic changes influence the biventricular noncompaction phenotype, necessitating vigilant monitoring for left heart failure in foetal-onset biventricular noncompaction cases with <i>MYH7</i> variants.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneously resolved pseudoaneurysm after valve-sparing aortic root replacement in Marfan syndrome: a case report - CORRIGENDUM.","authors":"Eun Chae Kim, Jooncheol Min, Jae Gun Kwak","doi":"10.1017/S1047951126112852","DOIUrl":"https://doi.org/10.1017/S1047951126112852","url":null,"abstract":"","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1"},"PeriodicalIF":0.7,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147834167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics and outcomes of patients with occlusion of the left main trunk caused by Kawasaki disease.","authors":"Etsuko Tsuda","doi":"10.1017/S1047951126112098","DOIUrl":"https://doi.org/10.1017/S1047951126112098","url":null,"abstract":"<p><p><i>Background</i>: The outcome of a coronary artery aneurysm at the bifurcation of the left coronary artery caused by Kawasaki disease affects myocardial involvement, which is related to the left ventricular function and outcome of patients. <i>Methods</i>: A total of eighteen (13 males, 5 females) patients with left main truncus occlusion between 1978 and 2022 were reviewed based on their medical records and selective coronary angiograms. <i>Results</i>: Most patients had a giant aneurysm at the bifurcation of the left coronary artery. There were two groups based on the timing of the left main trunk occlusion. In the one-time occlusion group, all seven patients had nearly fatal cardiac events. In the second-step occlusion group, 8 (73%) of 11 patients had asymptomatic occlusions of the left main trunk; they underwent grafting to the left anterior descending artery. The median ages at the left main trunk occlusion in the one-time and the second-step group were 18.1 years (range 4.9 to 26.3) and 25.0 years (2.2 to 45.0), respectively. In the second-step group, the median interval from the coronary artery bypass grafting to the left main truncus occlusion was 7.9 years (6 days to 24.5 years). Their left ventricular ejection fraction ranged from 20 to 65% (mean 49%). <i>Conclusion</i>: To prevent either a fatal cardiac event or a low left ventricular function, a coronary artery bypass graft to the left anterior descending artery was recommended at an optimal time in each patient with a giant aneurysm of the left main trunk complicating a stenotic lesion of the left anterior descending artery.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-9"},"PeriodicalIF":0.7,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A persistent right umbilical vein poses challenges for stent placement in the ductus venosus.","authors":"Makiko Sakamoto, Tetsuko Ishii, Akiko Omoto","doi":"10.1017/S1047951126112293","DOIUrl":"https://doi.org/10.1017/S1047951126112293","url":null,"abstract":"<p><p>We report a case of prenatally diagnosed asplenia syndrome complicated by an infracardiac type total anomalous pulmonary venous connection. Stenting the ductus venosus through the umbilical vein was unsuccessful owing to the persistence of the right umbilical vein. Umbilical veins can develop various anomalies. When the fetus is planned for catheter intervention immediately after birth, the umbilical vein structure should be evaluated at the prenatal stage.</p>","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-3"},"PeriodicalIF":0.7,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147763311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}