Cardiology in the Young最新文献

Resolution of late-onset bigeminy following percutaneous transcatheter balloon valvuloplasty of the aortic valve stenosis in paediatric. 小儿主动脉瓣狭窄经皮球囊成形术后迟发性重症症的解决。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-06 DOI: 10.1017/S1047951125109876

Mohd Rizal Mohd Zain, Saravanan Krishinan, Anis Munirah Mohd Kori

引用次数: 0

Trends in procedure choice, cost, and health outcomes in infants undergoing Stage 1 palliation for hypoplastic left heart syndrome: a retrospective analysis of the Paediatric Health Information System. 治疗左心发育不全综合征的1期患儿手术选择、费用和健康结果的趋势：儿科健康信息系统的回顾性分析。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-06 DOI: 10.1017/S1047951125109992

Adam Dziacky, John Morrison, Jamie Fierstein, Joyce Johnson

{"title":"Trends in procedure choice, cost, and health outcomes in infants undergoing Stage 1 palliation for hypoplastic left heart syndrome: a retrospective analysis of the Paediatric Health Information System.","authors":"Adam Dziacky, John Morrison, Jamie Fierstein, Joyce Johnson","doi":"10.1017/S1047951125109992","DOIUrl":"https://doi.org/10.1017/S1047951125109992","url":null,"abstract":"Management of infants with hypoplastic left heart syndrome is resource-intensive. Trends in initial Stage 1 palliation choice and associated hospital cost and outcomes over time are unclear.Using a retrospective cohort of infants <30 days of age (2004-22) from the Paediatric Health Information Systems database, we analysed the annual prevalence of Stage 1 palliation choice, as well as the association between palliation choice and outcomes and resource use. Prevalence of palliation choice was calculated, and Mann-Kendall tests evaluated linear trends. Study outcomes were pooled across years and compared by palliation choice. Associations over time between palliation choice and outcomes and resource use were evaluated with generalised linear mixed models.Of 7701 patients, 67.45% (n = 5194) underwent a Norwood with modified Blalock-Taussig shunt, (NmBT) 22.06% (n = 1699) underwent a Norwood with right ventricle to pulmonary artery conduit (NRVPA), and 10.49% (n = 808) underwent a hybrid procedure. The annual prevalence of NRVPA surpassed that of NBT in 2017. In the pooled analysis, infants undergoing NRV-PA had the lowest in-hospital mortality (11.2%, P < 0.0001) and lowest cost at $335,406 (IQR: $208,624 to $583,322 (P = 0.001). A trend for increased median estimated hospitalisation cost was observed across time for all procedure choices (P for trend <0.0001 for all).These data suggest that the NRV-PA is the preferred palliation choice, has the lowest in-hospital mortality, and is the most cost-effective option. Our findings suggest that all Stage 1 palliation options have become more expensive with no observed change in mortality.","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-7"},"PeriodicalIF":0.7,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145231530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neonatal case of congenital dilated cardiomyopathy, cholestatic liver injury, and hyperferritinemia with FHL2 variant: a case report suggesting possible novel phenotypes. 新生儿先天性扩张型心肌病、胆汁淤积性肝损伤和高铁蛋白血症伴FHL2变异病例报告：提示可能的新表型

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-03 DOI: 10.1017/S1047951125109682

Hidenori Yamamoto, Naoki Ohashi, Taichi Kato

引用次数: 0

Challenges in ablating ventricular arrhythmias originating from the left ventricular summit region. 消融源自左心室顶区的室性心律失常的挑战。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-03 DOI: 10.1017/S1047951125109864

Musa Öztürk, İlker Ertuğrul, Tevfik Karagöz

{"title":"Challenges in ablating ventricular arrhythmias originating from the left ventricular summit region.","authors":"Musa Öztürk, İlker Ertuğrul, Tevfik Karagöz","doi":"10.1017/S1047951125109864","DOIUrl":"https://doi.org/10.1017/S1047951125109864","url":null,"abstract":"Background: Radiofrequency catheter ablation of ventricular arrhythmias, originating from the left ventricular summit, is challenging due to epicardial localisation of the substrate, surrounded by coronary arteries. This paper highlights the successful elimination of LVOT summit ventricular arrhythmia which was ablated from the aortic cusp and aortic mitral continuity in two paediatric patients.Case report: Ventricular tachycardia arising from the basal region of the left ventricular summit was identified in two male patients aged 9 and 13 years. Electroanatomic mapping of ventricular arrhythmia revealed the earliest ventricular signal within the left coronary artery which was successfully ablated from the left coronary cusp. The second patient with exactly similar ECG of ventricular arrhythmia was treated by delivering energy to the aorta-mitral continuity beneath the aortic valve. No recurrences were observed during the follow-up period of 20 months.Conclusion: Ventricular tachycardia arising from the basal region of the left ventricular summit is very rarely observed in paediatric patients. Utilising radiofrequency catheter ablation in proximity to the source can effectively and safely eliminate tachycardia.","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-4"},"PeriodicalIF":0.7,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unilateral absence of the pulmonary artery in a paediatric cohort. 一个儿科队列的单侧肺动脉缺失。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-03 DOI: 10.1017/S1047951125109979

Laia Brunet-Garcia, Flavio Zuccarino, Juan Manuel Carretero Bellon

引用次数: 0

Milestones in paediatric cardiology: how prostaglandins revolutionised the management of CHD. 儿科心脏病学的里程碑：前列腺素如何彻底改变冠心病的治疗。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-10-02 DOI: 10.1017/S104795112510975X

Daniel O'Meara, Michael Wolf, Matthew Eric Ferguson

引用次数: 0

Postnatal short-term outcomes of pulmonary atresia with ventricular septal defect following prenatal diagnosis: a preliminary Vietnamese report. 产前诊断肺动脉闭锁合并室间隔缺损的产后短期预后：越南初步报告。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-09-30 DOI: 10.1017/S1047951125109645

Linh Thuy Dinh, Quang-Vinh Tran

{"title":"Postnatal short-term outcomes of pulmonary atresia with ventricular septal defect following prenatal diagnosis: a preliminary Vietnamese report.","authors":"Linh Thuy Dinh, Quang-Vinh Tran","doi":"10.1017/S1047951125109645","DOIUrl":"https://doi.org/10.1017/S1047951125109645","url":null,"abstract":"Introduction: Pulmonary atresia with ventricular septal defect (PA/VSD) is a complex cyanotic CHD that requires an early diagnosis for optimal management and outcomes. The purpose of this study is to evaluate the effectiveness of an inter-hospital management protocol utilising the prenatal CHD diagnosis for achieving favourable postnatal outcomes in PA/VSD patients in Vietnam.Methods: We described the protocol implemented between two tertiary medical settings in Vietnam for the prenatal diagnosis and postnatal management of PA/VSD infants. All PA/VSD patients with prenatal diagnosis between January 2016 and December 2022 were retrospectively reviewed. The primary outcome was postnatal survival, and the secondary outcome was the presence of major morbidities such as bleeding or the need for Extra Corporeal Membrane Oxygenation (ECMO) after total repair.Results: During the study period, 35 PA/VSD patients were identified including 29 infants who underwent surgical correction utilising a valved conduit and 6 infants who are still waiting for the next evaluation after the palliative surgery. No death prior to the surgery occurred. For 29 patients, one hospital death happened, two patients required ECMO initially in their postoperative course but both survived, one late mortality due to pneumonia, and three reoperations were due to conduit failure. In the mean follow-up time of 2.92 (0.51-7.92) years, all survivors had completed follow-up.Conclusion: Our protocol including a multidisciplinary management and a close follow-up has shown promising short-term results in achieving favourable postnatal outcomes for PA/VSD patients.","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145190963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atypical clinical features in a young boy with LMNA mutation: expanding the spectrum of laminopathies. 不典型的临床特征在一个小男孩与LMNA突变：扩大谱板病。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-09-30 DOI: 10.1017/S1047951125109311

Nicoletta Cantarutti, Maria C Casarini, Fabrizio Drago

引用次数: 0

Double-orifice mitral valve causing left ventricular outflow tract obstruction: a hitherto unreported entity. 双孔二尖瓣导致左心室流出道阻塞：迄今未报道的实体。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-09-30 DOI: 10.1017/S1047951125109591

Ishita Garg, Sreeja Pavithran, Sivakumar Kothandam

引用次数: 0

Cerebral endovascular mechanical thrombectomy in CHD - a literature review and case series. 冠心病脑血管内机械取栓术的文献回顾和病例分析。

IF 0.7 4区医学

Cardiology in the Young Pub Date : 2025-09-29 DOI: 10.1017/S1047951125109499

Austin Adair, Maria Elisa Hoyos, Monica Sofia Ponce-Rivera, Stephen Deputy, Chelsey Ortman, Qingqing Wang, Hamidreza Saber, Charles D Fraser, Jeremy T Affolter

{"title":"Cerebral endovascular mechanical thrombectomy in CHD - a literature review and case series.","authors":"Austin Adair, Maria Elisa Hoyos, Monica Sofia Ponce-Rivera, Stephen Deputy, Chelsey Ortman, Qingqing Wang, Hamidreza Saber, Charles D Fraser, Jeremy T Affolter","doi":"10.1017/S1047951125109499","DOIUrl":"https://doi.org/10.1017/S1047951125109499","url":null,"abstract":"Background: CHD is a major risk factor for acute ischaemic stroke in paediatric patients due to endothelial changes from surgically manipulated vessels, prosthetic material, flow stasis in variable circulations, and hypercoagulability from chronic cyanosis. Stroke recognition in critically or chronically ill patients is challenging, yet rapid identification allows for mechanical thrombectomy to restore cerebral blood flow, particularly in those ineligible for thrombolysis or beyond its therapeutic window. We present a case series highlighting the importance of prompt stroke diagnosis and the role of mechanical thrombectomy in paediatric CHD patients, including children as young as four.Methods: We conducted a single-centre retrospective chart review of paediatric CHD patients who experienced thromboembolic stroke and underwent mechanical thrombectomy from July 2018 to March 2024. Data collected included age, stroke territory, maximum Paediatric NIH Stroke Scale (PedNIHSS) score, pre-thrombectomy neurological deficits, and post-thrombectomy outcomes using thrombolysis in cerebral infarction (TICI) scores.Results: Four CHD patients underwent mechanical thrombectomy for thromboembolic stroke (Table ). They exhibited diverse cardiac anatomies, including two-ventricle and single-ventricle physiology, with a wide age range at presentation.Conclusion: Stroke presentation in CHD patients is variable, necessitating a high index of suspicion. Mechanical thrombectomy is safe and effective in patients as young as four, with no haemorrhagic complications in this series. Further research is needed to develop tailored stroke management guidelines for paediatric CHD patients, particularly younger children and those ineligible for thrombolysis.","PeriodicalId":9435,"journal":{"name":"Cardiology in the Young","volume":" ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145184641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0