Recent advances in drug delivery and formulation最新文献

{"title":"A Comprehensive Review of Nanostructured Lipid Carriers: Innovations and Applications in Breast Cancer Treatment.","authors":"Prathamesh Mirajkar, Priyanka Ahlawat, Asha Patel, Shruti Patel, Drishti Panjwani","doi":"10.2174/0126673878313086241031154146","DOIUrl":"10.2174/0126673878313086241031154146","url":null,"abstract":"<p><p>Nanostructured Lipid Carriers (NLCs) represent a promising advancement in the treatment of breast cancer, addressing the significant challenges posed by conventional chemotherapy, such as poor drug solubility, short half-lives, and high toxicity. This review delves into the potential of NLCs to overcome these limitations, highlighting their unique structure comprising a solid and lipid liquid core stabilized by surfactants. By examining diverse lipid blends used in the preparation of NLCs, the article emphasizes their suitability for targeted drug delivery. Various facets of NLC configuration, categorization, composition, and formulation approaches are systematically explored to provide a comprehensive understanding of their attributes. The findings reveal that NLCs possess a high capacity for lipophilic drugs and offer advantages over traditional lipid-based nanocarriers. The review underscores the pivotal role of NLCs in enhancing drug delivery efficiency for breast cancer therapy while minimizing systemic toxicity. Conclusively, this review positions NLCs as a key player in the evolution of drug delivery systems for breast cancer treatment, providing a detailed outlook on their transformative potential and contributing to a nuanced understanding of their significance in advancing the field of breast cancer treatment.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"25-44"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Natural Extract-Loaded Herbal Patches: Assessment for Biomedical Application.","authors":"Shaheen Ansari, Pragya, Sikha Srivastava, Poonam Parashar","doi":"10.2174/0126673878330303241230102355","DOIUrl":"10.2174/0126673878330303241230102355","url":null,"abstract":"<p><strong>Introduction: </strong>Medicinal plants like <i>Moringa</i> and <i>Selaginella</i> have gained attention for their potential in wound healing including antimicrobial and antioxidant attributes. Extracts from these plants have shown promise in accelerating wound healing processes, enhancing fibroblast cell proliferation and migration, and providing antioxidant benefits. The objective of this work was to assess the therapeutic potential of extracts loaded patches for biomedical applications.</p><p><strong>Methods: </strong><i>Selaginella bryopteris L.</i> and <i>Moringa oleifera Lam</i>. extracts were prepared using the cold maceration method. The prepared extracts were evaluated for antibacterial activity and antioxidant potential. Additionally, patches were prepared using polyvinyl alcohol and hydroxypropyl methylcellulose as polymers and evaluated for <i>in vitro</i> release, cell viability and biocompatibility characteristics.</p><p><strong>Result: </strong>The extract of both plants showed good antioxidant potency against ascorbic acid. Antibacterial activity revealed that <i>Selaginella</i> and <i>Moringa</i> extracts as well as patches consistently outperformed P. aeruginosa, B. subtilis, and S. aureus at varying concentrations. Physiochemical evaluation of patches indicated good weight uniformity, thickness, and folding endurance, with slight moisture uptake. Drug release profiles showed significant results for all formulations. The results of cell viability for patches showed an increased cell proliferation and were nontoxic.</p><p><strong>Conclusion: </strong>The study suggests that both extract and patch show excellent antibacterial activity against Staphylococcus aureus. The characterization results showed that the patches were uniform in their drug content, weight, and thickness, and they also indicated the reproducibility of the method used. In the <i>in vitro</i> release study of <i>Selaginella bryopteris L.</i> and Moringa oleifera Lam. patches were fitted to the Higuchi model and also patches were found harmless for the cells as well as increased proliferation of cells.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"156-167"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143124306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Management of Rheumatoid Arthritis By Development of Nanocarriers and their Significance Over Conventional Dosage Forms.","authors":"Hafsa Khan, Nita Yadav, Shipra Sharma, Reetika Rawat","doi":"10.2174/0126673878324613240805065651","DOIUrl":"https://doi.org/10.2174/0126673878324613240805065651","url":null,"abstract":"<p><strong>Background: </strong>Rheumatoid Arthritis is one of the most common auto-immune diseases that cause inflammation. It is characterized by pain, stiffness, tenderness, and swelling in joints, which may even lead to heart, lungs, or brain-related problems where age is the major factor involved, as around 55% older adults have been affected by it. Treatments including non-steroidal anti- inflammatory drugs (NSAIDs), disease-modifying anti-rheumatic drugs (DMARDs) etc., that are modified and formulated as nanocarriers for enhanced bioavailability, majorly aim at enhancing the rate and extent of drug reaching the bloodstream such as solid-lipid nanoparticles, liposomes, polymeric- micelles, polymeric nanoparticles etc. are used in the management of rheumatoid arthritis.</p><p><strong>Methods: </strong>The following tools (Pubmed, Scopus, Google search engine, Google Scholar, Medline Search Engine, Elsevier) were used in the literature search.</p><p><strong>Results: </strong>Through the literature review, the development of nanocarrier shows a promising approach in the management of rheumatoid arthritis as compared to the conventional drug treatment such as biologic agents and non-steroidal anti-inflammatory drugs etc. Conclusion: Rheumatoid Arthritis is a condition that occurs when the immune system, which normally helps to protect the body from infection and disease, attacks its own tissues. The disease causes pain, swelling as well as loss of function in joints. Therefore, life-long management is required by reducing the dose frequency and dosage regimen, which can be effectively approached by the development of a nano-carrier for significant drug uptake and low toxicity.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":"19 1","pages":"2-15"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Scientific and Technological Prospecting on Polymeric Particles Containing Extracellular Matrix Peptides for the Treatment of Duchenne Muscular Dystrophy.","authors":"Livia Alves Filgueiras, Francisco Thiago Bandeira Silva, Francisco das Chagas Alves Lima, Anderson Nogueira Mendes","doi":"10.2174/0126673878329404250106065202","DOIUrl":"10.2174/0126673878329404250106065202","url":null,"abstract":"<p><p>Duchenne muscular dystrophy is a neuromuscular disease with an overall incidence of between 1 in 5,000 newborn males. Carriers may manifest progressive muscle weakness, resulting from the progressive degeneration of skeletal muscles, generating cardiac and respiratory disorders. Considering the lack of effective treatments, different therapeutic approaches have been developed, such as protein synthesis and extracellular matrix derivatives that can be used to improve muscle regeneration, maintenance, or repair. At the same time, the use of other anti-inflammatory drugs or biological agents to replace corticosteroids conjugated to these extracellular matrix derivatives may act more effectively in controlling the progression of Duchenne muscular dystrophy. Extracellular matrix-derived peptides (e.g. laminin-111 derivatives) and the use of essential oils with antiinflammatory activity in polymeric particles for application in the treatment of Duchenne muscular dystrophy are discussed. For this purpose, the literature of patents and scientific articles from 2012- 2024 on LM-111 peptides and Duchenne muscular dystrophy was reviewed. Many patents focus on palliative technologies that seek to prolong the progressive effects of the disease, considering the control of the inflammatory process. The technological and scientific prospecting suggests the need for continuous research on systems that can serve as a treatment for Dystrophy.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"105-126"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143069577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chitosan: Microsphere Formulation and Characterization for Slow - Release Prebiotic Activities in Gut Microbiota Remodelling.","authors":"Sunny Kumar, Zeel Bhatia, Sriram Seshadri","doi":"10.2174/0126673878305913241122114556","DOIUrl":"10.2174/0126673878305913241122114556","url":null,"abstract":"<p><strong>Introduction: </strong>Chitosan is a biocompatible, mucoadhesive, and biodegradable polymer widely used for various purposes due to its biological activity and safety. The current study aimed to formulate Chitosan microspheres and conduct an in-vitro evaluation of their cytotoxicity. The concept is focused on targeted gut delivery and biological activities in gut microbiota remodelling.</p><p><strong>Methods: </strong>The formulations were comprehensively characterized, encompassing SEM for surface morphology, particle size analysis, and FT-IR for structural understanding. Along with biological activity and cytotoxicity studies, dissolution efficiency was considered to understand release kinetics potential and accelerated stability studies to predict formulation shelf-life.</p><p><strong>Results: </strong>The formulation showed smooth spherical surface morphology with an average size range of 30.0 ± 5.0 μm and a charge of 20.35 ± 0.35 mV. Further, functional and thermal properties were determined using FT-IR and DSC, respectively. The microspheres showed a potent prebiotic potential in gut flora isolated and processed from a faecal sample of Wistar rats with prolonged release characteristics in the dissolution study. A cytotoxicity study using rat intestinal epithelial cells (IEC6) indicated that 40 mg /kg of microspheres could be considered an optimal dose for an <i>in-vivo</i> study.</p><p><strong>Conclusion: </strong>The formulation demonstrated promising pharmaceutical applicability due to its potential prebiotic nature and slow release into the gut environment. After a thorough in vivo study, the microspheres can be broadly used to restore gut dysbiosis due to their potential prebiotic activities in various diseases and disorders, including but not limited to obesity, type-2 diabetes, cardiometabolic disease, and non-alcoholic fatty liver disease.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"45-52"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking Dendrimers Future Potential for Brain-Specific Drug Delivery in Cerebroanoreach.","authors":"Aditya Jain, Shikha Yadav, Javed Khan","doi":"10.2174/0126673878303735240906065735","DOIUrl":"https://doi.org/10.2174/0126673878303735240906065735","url":null,"abstract":"<p><p>The Blood-Brain Barrier (BBB) makes it extremely difficult to get drugs to the brain, yet highly branching macromolecules known as dendrimers show a lot of promise in this regard. This review delves into the current and future prospects of dendrimers in facilitating brain-specific drug delivery within the framework of cerebroanoreach. The unique structural features of dendrimers allow for precise regulation of surface function, size, and shape, which are critical for targeting specific cell types in the brain and increasing blood-brain barrier permeability. Second, they can be conjugated with imaging agents, peptides, or pharmaceuticals thanks to their versatile surface chemistry, which enhances diagnostic capabilities and treatment efficacy. Recent advances in nanoformulations based on dendrimers have demonstrated promising improvements in the solubility, stability, and bioavailability of medications, suggesting their possible use in therapeutic contexts. Various obstacles, such as toxicity profiles and production bottlenecks that require scaling up are also addressed, with a focus on ongoing research projects and potential remedies. One potential solution to the problems with cerebroanoreach is the use of dendrimers for brain-specific drug delivery; this could revolutionize the treatment of neurological diseases and the precision of neurology diagnostics. By synthesizing current knowledge and future directions, this review urges the continuance of interdisciplinary collaboration, which is crucial for fully realizing the potential of dendrimers in neuroscience and therapeutic innovation.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":"19 1","pages":"16-24"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144268286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-Ionic Surfactant Vesicles (Niosomes): Structure, Functions, Classification and its Advances in Enhanced Drug Delivery.","authors":"Pavan Kumar Padarthi, V Kalvimoorthi, Ranadheer Reddy Challa, Bhaskar Vallamkonda, Neelima Grandhe, Lakshman Kumar Dogiparthi, Rajaganapathy Kaliyaperumal","doi":"10.2174/0126673878322982241126103404","DOIUrl":"10.2174/0126673878322982241126103404","url":null,"abstract":"<p><p>Non-ionic surfactant vesicles, commonly known as niosomes, have gained significant attention in the field of drug delivery because of their unique properties and advantages. Niosomes are self-assembled vesicles composed of non-ionic surfactants and cholesterol that can entrap both hydrophilic and hydrophobic drugs within their aqueous core or bilayer. This versatile drug delivery system offers improved stability, prolonged release profiles, reduced toxicity, and enhanced efficacy for a wide range of therapeutic agents. This comprehensive article delves into the structure, function, classification, and advances in niosomes for enhanced drug delivery. It explores various nonionic surfactants used for niosome formulation and discusses their impact on encapsulation efficiency and stability. Moreover, it highlights the application of niosomes in the delivery of small molecules, proteins, and plant-derived natural products. This article provides an overview of the different formulation methods employed for niosome preparation and discusses recent advancements that have expanded their potential applications in targeted drug delivery systems.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"87-104"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treating Burn Infections With Topical Delivery of Positively Charged Norfloxacin-Loaded Lipid-Polymer Hybrid Nanoparticles.","authors":"Kamilia H A Mohammed, Fatma Rasslan, Marwa A Abd El-Fattah, Seham Shawky, Omnya M Amin, Heba A Eassa","doi":"10.2174/0126673878316672241122041157","DOIUrl":"10.2174/0126673878316672241122041157","url":null,"abstract":"<p><strong>Background: </strong>Norfloxacin (NFX) is a wide-spectrum antibacterial agent that suffers from low water solubility and first-pass metabolism. This diminishes its oral bioavailability by 60-70%.</p><p><strong>Objective: </strong>This work aims to formulate a topical gel of NFX-loaded lipid polymer hybrid nanoparticles (NFX-LPHNPs) that combine the merits of liposomes and polymeric nanoparticles to overcome these problems.</p><p><strong>Methods: </strong>NFX-LPHNPs formulations were developed using Precirol ATO (lipid) and Eudragit RL100 (polymer). They were characterized for particle size, uniformity of distribution, entrapment efficiency, zeta potential, and in-vitro release. Box-Behnken design was applied to study sequentially different variables' impact on material attributes. Then the optimized formula was re-evaluated, and incorporated in an HPMC-gel formulation. The gel formulation was evaluated for its physical properties, <i>in vitro</i>-release, and antibacterial activity.</p><p><strong>Results: </strong>NFX-LPHNPs exhibited particle sizes ranging from 28.92 to 730.30 nm. Particles were uniformly distributed with a positively charged surface (indicated by zeta potential with values from +3.91 to +60.2 mV). Formulations showed a % cumulative drug release of 87.9-100% in 8 h. The optimized formula showed a satisfied fit of measured-to-predicted responses with 159 nm particle size, 92.61% release and 79.2% entrapment efficiency. Gel formulation showed a sustained release over 24 h. Antibacterial testing against <i>Staphylococcus aureus, Acinetobacter baumannii</i> and <i>Pseudomonas aeruginosa</i> revealed enhanced activity of NFX-LPHNPs against these pathogens compared to bare NFX loaded gel.</p><p><strong>Conclusion: </strong>These results illustrated the high potential of lipid-polymer hybrid nanoparticles to improve NFX activity against resistant pathogens common in burn infections. Moreover, the topical application helps overcome Norfloxacin oral-associated problems.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":"142-155"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142808981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Precision Oncology: Advances in Drug Delivery and Imaging.","authors":"Suraj Kumar, Sathvik Belagodu Sridhar, Rishabha Malviya, Bhupendra G Prajapati","doi":"10.2174/0126673878332787241210102302","DOIUrl":"https://doi.org/10.2174/0126673878332787241210102302","url":null,"abstract":"<p><p>The development of precise and reliable cancer treatments has been a long-standing goal in oncology. Conventional therapies often affect healthy tissues, leading to significant side effects. To overcome these challenges, researchers are exploring new methodologies that combine advanced drug delivery systems with state-of-the-art imaging technologies to target tumors more effectively. This study aims to investigate a novel approach that integrates smart drug delivery systems with real-time imaging modalities. The goal is to enhance the targeted delivery of therapeutic agents to cancer cells, minimizing damage to healthy tissues while improving the overall efficacy of cancer treatments. Smart drug delivery systems are designed to transport medications directly to tumor sites, enhancing treatment precision. When combined with real-time imaging tools such as MRI, CT, PET, and molecular imaging, these systems offer real-time data on the tumor's location, size, and response to treatment. This allows for immediate adjustments in therapy, ensuring optimal drug delivery and reducing side effects. However, the implementation of this approach also faces challenges, including the need for stringent safety protocols and adherence to regulatory standards. The integration of advanced drug delivery systems with cutting-edge imaging technologies presents a promising approach to cancer therapy. By enabling more precise treatment targeting and reducing adverse effects, this strategy has the potential to significantly improve patient outcomes in the fight against cancer.</p>","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced Oral Bioavailability and Stability Studies of Loratadine Tablets\u0000Based on Solid Dispersion of Modified Ziziphus spina-christi Gum","authors":"Ameen M. Alwossabi, E. S. Elamin, Elhadi M. M. Ahmed, Eman A. Ismail, A. Ashour, W. Osman, A. E. Sherif, Amira Mira, Rawan Bafail, Yusra Saleh Andijani, Sabrin R. M. Ibrahim, Gamal A. Mohamed, Mohammed Abdelrahman","doi":"10.2174/0126673878288535240530113418","DOIUrl":"https://doi.org/10.2174/0126673878288535240530113418","url":null,"abstract":"\u0000\u0000Solid dispersion is a common technique used for solubility enhancement of\u0000poorly soluble drugs.\u0000\u0000\u0000\u0000In this study, loratadine (LOR), a class II biopharmaceutical classification system (BCS),\u0000was formulated as solid dispersion tablets using modified Ziziphus spina-christi gum (MZG) as a\u0000carrier.\u0000\u0000\u0000\u0000The solvent evaporation method was used for LOR-MZG solid dispersion (SD) preparation.\u0000A variety of tests were conducted to characterize and optimize the formulation. Solubility,\u0000Fourier transform infrared (FTIR) analysis, Differential Scanning Calorimetry (DSC), X-Ray Diffraction\u0000(X-RD), and Scanning Electron Micrograph (SEM) of solid dispersions were carried out.\u0000Accelerated stability testing and pharmacokinetic studies of formulated tablets were also performed\u0000using albino Wistar rats.\u0000\u0000\u0000\u0000Solid dispersion improved the solubility of LOR by 51 folds. FTIR spectra excluded drugpolymer\u0000interactions, and results obtained by DSC, X-RD, and SEM proved the transition from the\u0000crystalline to the amorphous state. The stability of LOR-MZG solid dispersion tablets was found to\u0000be better when the Alu-Alu package was used. The pharmacokinetics of LOR-MZG compared to\u0000MZG-free loratadine tablets (LOR pure) and commercial loratadine tablets (LOR-TM) following\u0000oral administration revealed that about 6 folds and 10 folds bioavailability were achieved with\u0000LOR-MZG compared to LOR pure and LOR-TM, respectively.\u0000\u0000\u0000\u0000Such promising results encourage more studies on MZG to be used for improving the\u0000aqueous solubility and bioavailability of a wide range of poorly soluble drugs.\u0000","PeriodicalId":94352,"journal":{"name":"Recent advances in drug delivery and formulation","volume":"22 18","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141378968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}