Anesthesia progress最新文献

Examining Liposomal Bupivacaine's Use in Dentistry. 布比卡因脂质体在牙科中的应用研究。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/321278

Kyle J Kramer

引用次数: 0

Postoperative Nausea and Vomiting After Minor Oral Surgery: A Retrospective Cohort Study. 小口腔手术后恶心呕吐：一项回顾性队列研究。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/611198

Fumika Ogata, Tina Nakamura, Hiroshi Hoshijima, Katsushi Doi, Hiroshi Nagasaka, Tsutomu Mieda

{"title":"Postoperative Nausea and Vomiting After Minor Oral Surgery: A Retrospective Cohort Study.","authors":"Fumika Ogata, Tina Nakamura, Hiroshi Hoshijima, Katsushi Doi, Hiroshi Nagasaka, Tsutomu Mieda","doi":"10.2344/611198","DOIUrl":"10.2344/611198","url":null,"abstract":"Objective: This study aimed to determine whether PONV rates differed over time and to identify potential differences in PONV risk factors for oral surgery patients undergoing general inhalational anesthesia (IA) or propofol-based total intravenous anesthesia (TIVA).Methods: This retrospective cohort study included patients between 16 and 85 years of age and who received intubated general anesthesia with either IA or TIVA for minor oral surgery between January 2021 and July 2022. Primary outcomes were PONV overall (onset at 0-24 hours), early (onset at 0-2 hours), and late (onset at 2-24 hours). Known PONV risk factors as identified from existing literature were included for analysis.Results: Data were obtained from 188 patients. A total of 41 (21.8%) patients developed overall PONV, 35 patients (18.6%) had early PONV, and 14 patients (7.4%) had late PONV. Any PONV that occurred across 2 periods was categorized in each period. IA compared with TIVA had higher overall PONV (29.6% vs 13.3%; P = .008) and early PONV (25.5% vs 11.1%; P = .034). Female sex and increased Apfel scores were associated with increased overall, early, and late PONV. Per multivariate analysis, females were 2.5 to 6 times higher than males to have overall, early, and late PONV (P < .05), and IA was 3 times higher than TIVA to have overall and early, but not late, PONV (P < .05).Conclusion: Our results suggested that the method of anesthesia may impact the incidence of overall and early PONV and that female sex and increase Apfel scores correlated with increased PONV through all times.","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 4","pages":"163-170"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Current Literature of Interest to the Office-Based Anesthesiologist. 对办公室麻醉师感兴趣的当前文献综述。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/690585

Mark A Saxen

引用次数: 0

Liposomal Bupivacaine Use in Third Molar Impaction Surgery: INNOVATE Study. 布比卡因脂质体在第三磨牙嵌塞手术中的应用：创新研究。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/333161

Stuart E Lieblich, Hassan Danesi

{"title":"Liposomal Bupivacaine Use in Third Molar Impaction Surgery: INNOVATE Study.","authors":"Stuart E Lieblich, Hassan Danesi","doi":"10.2344/333161","DOIUrl":"10.2344/333161","url":null,"abstract":"The analgesic efficacy and safety of liposomal bupivacaine (LB) in third molar extraction was evaluated in this phase 3, double-blind, placebo-controlled study of subjects undergoing bilateral third molar extraction. Subjects were randomized 2: 1 to infiltration with LB (133 mg/10 mL) or placebo, and received opioid rescue medication as needed. Primary efficacy measure was cumulative area under the curve (AUC) of numeric rating scale (NRS) pain severity scores through 48 hours (AUC of NRS0-48) postsurgery. Other measures included AUC of NRS0-24, AUC of NRS0-72, and AUC of NRS0-96, and incidence of adverse events. There were 150 subjects in the primary efficacy population (n = 99 LB, n = 51 placebo) and 89 in the per-protocol population (n = 59 LB, n = 30 placebo). Least-squares mean for AUC of NRS0-48 was 172.3 LB versus 194.7 placebo (P = .227) in the primary efficacy population and 120.8 LB versus 183.3 placebo (P = .023) in the per-protocol population. At all time points, between-group differences in AUC of NRS scores were significant in the per-protocol population (LB lower than placebo, P < .05) but not in the primary efficacy population. The adverse event profile was similar between groups. LB produced significantly lower cumulative pain scores versus placebo at all time points in the per-protocol analysis but not in the primary efficacy analysis because of protocol violations. This study indicates significant improvement in pain scores in the third molar model, but because of extensive protocol violations additional studies are warranted to demonstrate effectiveness.","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 4","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of Ketamine's Influence on In Vitro Angiogenesis. 氯胺酮对体外血管生成影响的评价。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/23-0011

Kazumi Takaishi, Marina Takata, Mika Nishikawa, Hiroshi Kitahata, Shinji Kawahito

{"title":"Assessment of Ketamine's Influence on In Vitro Angiogenesis.","authors":"Kazumi Takaishi, Marina Takata, Mika Nishikawa, Hiroshi Kitahata, Shinji Kawahito","doi":"10.2344/23-0011","DOIUrl":"10.2344/23-0011","url":null,"abstract":"Objective: Angiogenesis is associated with angiogenic therapy and wound healing processes. It is important for anesthesiologists to understand the effects of perioperative and long-term use of anesthetics on angiogenesis. This study aimed to determine the effects of ketamine on in vitro angiogenesis: the proliferation of human umbilical vein endothelial cells (HUVEC) and normal human diploid fibroblasts (NHDF), HUVEC migration, and in vitro capillary tube formation in cocultured HUVEC and NHDF.Methods: The effects of ketamine at concentrations of 1, 10, and 50 µM on the proliferation of HUVEC and NHDF for 48 hours were determined by using a water-soluble tetrazolium salt reagent. Quantitation of migration for 22 hours was achieved by measuring the fluorescence of migrating HUVEC exposed to ketamine using an angiogenesis system. The effects of ketamine on capillary tube formation with or without vascular endothelial growth factor (VEGF) were investigated in cocultured HUVEC and NHDF incubated for 3 and 10 days.Results: Ketamine did not show any enhancing or suppressive effects on the in vitro proliferation of HUVEC and NHDF, HUVEC migration, or capillary tube formation in cocultured HUVEC and NHDF for either 3 or 10 days in the presence or absence of VEGF.Conclusion: Ketamine had no effects on in vitro angiogenesis using cultured HUVEC and NHDF. Ketamine can potentially be used as an anesthetic agent with no influence on angiogenesis.","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 4","pages":"176-182"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Suspected Sinus Arrest After Sugammadex Administration: A Case Report. 糖美德给药后疑似窦性停搏1例。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/anpr-23-0054

Takuya Uchida, Tamao Ikuno, Yoshinori Ikeda, Mie Ueda, Akina Toya, Yozo Manabe, Yoshihiro Momota

引用次数: 0

Multiple Abnormal Cutaneous Findings in a Patient With Hypomelanosis of Ito Undergoing General Anesthesia. 伊藤低黑素症患者接受全身麻醉的多重皮肤异常表现。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/23-0025

Misato Kobashi, Hiroyo Yoshimoto, Hanako Ohke, Kenji Goh, Naomasa Fujita, Kaho Mizuno, Kaisei Saitoh, Satomi Ando, Masato Saitoh, Makoto Terumitsu

{"title":"Multiple Abnormal Cutaneous Findings in a Patient With Hypomelanosis of Ito Undergoing General Anesthesia.","authors":"Misato Kobashi, Hiroyo Yoshimoto, Hanako Ohke, Kenji Goh, Naomasa Fujita, Kaho Mizuno, Kaisei Saitoh, Satomi Ando, Masato Saitoh, Makoto Terumitsu","doi":"10.2344/23-0025","DOIUrl":"10.2344/23-0025","url":null,"abstract":"Hypomelanosis of Ito (HI), a neurocutaneous syndrome, is characterized by skin depigmentation and skeletal, muscular, central nervous system, cardiac, and renal manifestations. A wide variety of cutaneous manifestations besides depigmentation have been reported. Herein we describe a 23-year-old woman with HI whose extracutaneous symptoms included severe mental and motor impairment, convulsions, and deformity of the orofacial region. She also had severe obesity, asthma, multiple allergies, and skin hypersensitivity. Although no extracutaneous manifestations were problematic during perioperative management of dental procedures under general anesthesia, erythema developed at 3 time points: during induction, during emergence, and in recovery. We speculated that mechanical stimuli to the skin and administration of multiple drugs likely caused histamine release, leading to the 3 episodes of erythema. Because patients with HI often have hypersensitivity reactions in the skin, both cutaneous and extracutaneous manifestations should be considered in the anesthetic management of patients with HI.","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 4","pages":"188-193"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthetic Management of a Patient With a Giant Hemangioma Who Required Urgent Embolization for Bleeding During Third Molar Extractions. 一例巨大血管瘤患者在第三磨牙拔除过程中因出血需要紧急栓塞治疗的麻醉处理。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/23-0038

Toru Yamamoto, Shigenobu Kurata, Tomoaki Ujita, Naotaka Kishimoto, Yuzo Imai, Emi Sawada, Hiroko Kanemaru, Yutaka Tanaka, Kenji Seo

引用次数: 0

Experience of General Anesthesia for Glossopexy in Infants With Robin Sequence. 全麻用于婴儿罗宾顺序光论术的体会。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/anpr-24-0004

Chiaki Yoshikawa, Chizuko Yokoe, Hiroharu Maegawa, Hitoshi Niwa

引用次数: 0

Dental Suction Interference and Acoustic Respiratory Monitoring. 牙吸干扰与呼吸声监测。

Anesthesia progress Pub Date : 2024-12-04 DOI: 10.2344/23-00017

Eimi Tabata, Yoshitaka Shimizu, Kana Oue, Noboru Saeki, Shinichiro Ohshimo, Akari Mukai, Hitomi Ishikawa, Hisanobu Kamio, Mitsuhiro Yoshida, Nobuaki Shime

{"title":"Dental Suction Interference and Acoustic Respiratory Monitoring.","authors":"Eimi Tabata, Yoshitaka Shimizu, Kana Oue, Noboru Saeki, Shinichiro Ohshimo, Akari Mukai, Hitomi Ishikawa, Hisanobu Kamio, Mitsuhiro Yoshida, Nobuaki Shime","doi":"10.2344/23-00017","DOIUrl":"10.2344/23-00017","url":null,"abstract":"Objective: Previous studies have reported that the noise generated by dental equipment can interfere with the auscultation of respiratory sounds during sedation. Therefore, this study aimed to identify whether positing the acoustic sensor on the chest or cervical position would be least susceptible to interference from dental suction device noise, a prominent noise noted during respiratory sound monitoring during dental sedation.Methods: This prospective cohort study was conducted with 30 students. Sound intensity (dB) and frequency (kHz) levels from the dental suction were recorded from the cervical and chest regions under both oral and nasal breathing conditions and analyzed.Results: The mean intensity of dental suction sounds was significantly lower in the chest region compared with the cervical region, regardless of the breathing condition (P < .001). Furthermore, in the chest region, the mean sound frequency during oral breathing was significantly lower than that during nasal breathing (P < .01).Conclusions: Our study suggests that monitoring respiratory sounds in the chest region can significantly reduce interference from noise generated by dental suction devices compared with monitoring at the cervical region.","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"71 4","pages":"171-175"},"PeriodicalIF":0.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11614464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142879159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0