{"title":"Revisiting the Posterior Superior Alveolar Nerve Block in Modern Practice.","authors":"Anuj Jain","doi":"10.2344/25-0019","DOIUrl":"10.2344/25-0019","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 2","pages":"116-118"},"PeriodicalIF":0.0,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13266606/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148267563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of Oral Muscle Relaxants Used for Chronic Temporomandibular Disorder Pain.","authors":"Dharm Patel, Aviv Ouanounou","doi":"10.2344/25-0020","DOIUrl":"10.2344/25-0020","url":null,"abstract":"<p><p>Temporomandibular disorders (TMDs) comprise a group of multifactorial conditions involving the masticatory muscles, temporomandibular joint, and associated structures influenced by biomechanical, neuromuscular, and biopsychosocial factors. Myogenous TMDs may involve muscle hyperactivity, parafunction, and central sensitization, contributing to chronic pain and functional limitation. Oral skeletal muscle relaxants (SMRs) are commonly used as adjunctive pharmacologic therapy; however, these agents vary considerably in mechanism, efficacy, and safety. This review summarizes the pharmacology, clinical evidence, and risk profiles of commonly prescribed SMRs-including cyclobenzaprine, baclofen, tizanidine, and others-within the context of chronic TMD management. Evidence supports short-term benefit for select agents, though data for chronic daily use remain limited. Given concerns regarding sedation, dependence, hepatotoxicity, and interactions with polypharmacy, clinicians should employ these medications judiciously and primarily for acute exacerbations rather than long-term therapy. An evidence-based, multimodal approach remains essential for optimizing care in patients with chronic TMDs.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 2","pages":"120-129"},"PeriodicalIF":0.0,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13266617/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148267577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Severe Bradycardia Induced by Mechanical Stimulation of the Nasal Cavity Under General Anesthesia.","authors":"Masanori Tsukamoto, Yukie Shirakawa, Miyoko Yutoku, Mitsutaka Sugimura","doi":"10.2344/24-0050","DOIUrl":"10.2344/24-0050","url":null,"abstract":"<p><p>The trigeminocardiac reflex (TCR) is clinically defined as the sudden onset of increased parasympathetic activity resulting from stimulation of the trigeminal nerve. This reflex increases parasympathetic tone and can lead to significant bradycardia and hypotension. We report the case of severe bradycardia and hypotension that occurred under general anesthesia during insertion of a cotton swab into the nasal cavity. A 57-year-old woman was scheduled for nasotracheal intubation for oral surgery, and following loss of consciousness, intubation was initiated using cotton swabs soaked in a solution of 2% lidocaine and 1:100,000 epinephrine that were inserted through the left nostril. The patient immediately developed severe bradycardia and hypotension which were managed with intravenous ephedrine after removing the cotton swabs rather than atropine due to concerns related to closed-angle glaucoma. The patient responded promptly to the ephedrine bolus, and no further complications occurred. It was assumed that the ophthalmic (V1) and maxillary (V2) branches of the trigeminal nerve were stimulated by the cotton swabs being inserted into the nasal cavity, triggering the TCR. Anesthesiologists need to be aware of the risks associated with administering mydriatic drugs such as ephedrine and epinephrine, which are relatively contraindicated, as well as atropine to patients with closed-angle glaucoma.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 2","pages":"106-109"},"PeriodicalIF":0.0,"publicationDate":"2026-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13266598/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148267745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Remifentanil Diminishes Stimulation-Induced Oral Tissue Blood Flow Changes.","authors":"Yasuhiro Jinbo, Masataka Kasahara, Kyotaro Koshika, Yui Akiike, Tatsuya Ichinohe","doi":"10.2344/24-0033","DOIUrl":"10.2344/24-0033","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate the effects of remifentanil infusion under inhaled anesthesia on changes in oral tissue blood flow and tissue oxygen tension during noxious stimulation of the oral region.</p><p><strong>Methods: </strong>Sixteen male Japan White rabbits were used. General anesthesia was maintained with sevoflurane or desflurane. Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean blood pressure (MAP), heart rate (HR), mandibular bone marrow tissue blood flow (BBF), masseter muscle tissue blood flow (MBF), mandibular bone marrow tissue oxygen tension (PbO2), and masseter muscle tissue oxygen tension (PmO2) were measured before and after electrical stimulation, with and without remifentanil.</p><p><strong>Results: </strong>Remifentanil decreased the rate of change in SBP, DBP, MAP, BBF, and MBF, whereas PbO2 and PmO2 remained unchanged.</p><p><strong>Conclusion: </strong>Remifentanil suppressed hemodynamics and oral tissue blood flow changes after electrical stimulation and maintained oral tissue oxygen tension.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"14-21"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976868/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Updates to Anesthesia Progress and the CDT Codes.","authors":"Kyle J Kramer","doi":"10.2344/Editorial_73_1","DOIUrl":"10.2344/Editorial_73_1","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"1-2"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976864/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147438687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Review of Current Literature of Interest to the Office-Based Anesthesiologist.","authors":"Mark A Saxen","doi":"10.2344/73.1.65","DOIUrl":"10.2344/73.1.65","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"65-67"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976873/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147461495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kristin D Sweeney Marso, Jin Peng, Beau D Meyer, Ehsan Azadani, Homa Amini, Paul Casamassimo
{"title":"Assessing Pediatric Sedation Using Patient-Centered Outcomes.","authors":"Kristin D Sweeney Marso, Jin Peng, Beau D Meyer, Ehsan Azadani, Homa Amini, Paul Casamassimo","doi":"10.2344/24-0016","DOIUrl":"10.2344/24-0016","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate pediatric dental sedation success using patient-centered outcomes overall and for behavior, safety, and treatment.</p><p><strong>Methods: </strong>A cross-sectional study used existing clinical data of children 24 to 60 months of age undergoing first-time sedations (2015-2020) at a children's hospital. Outcomes included behavior success (Frankl score 3-4), safety success (vital signs maintained within 2 SDs of age- and sex-based norms), and treatment success. Overall success was defined as success in at least 2 subcategories. Descriptive statistics, bivariate comparisons, and multiple variable logistic regression were performed.</p><p><strong>Results: </strong>In 824 subjects (52.3% female, median age 36 months), overall sedation success was 69.3% (behavior, 49.0%; safety, 79.5%; and treatment, 62.1%). Number of medications (1 vs ≥2) did not affect any outcome measures of success. However, oral vs intranasal midazolam alone had higher behavioral (59.4% vs 44.6%; P < .001) and safety (85.6% vs 76.1%; P = .006) success rates. Age (OR, 95% CI; 1.75, 1.43-2.14; P < .001), male sex (5.53, 1.15-2.18; P = .01), and cooperative presedation behavior (1.79, 1.27-2.53; P = .001) significantly increased the odds of overall success.</p><p><strong>Conclusion: </strong>Overall sedation success was approximately 69.3%. Combination regimens were not associated with increased measures of success. Older age, male sex, and cooperative presedation behavior all predicted overall success.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"3-13"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Anesthetic Management of a Diabetic Patient With a Suspected Hyperosmolar Hyperglycemic State: A Case Report.","authors":"Akiyo Kawano, Yuka Honjo, Mika Inoue, Masayoshi Hayashi, Chiho Kudo, Hitoshi Niwa","doi":"10.2344/24-0054","DOIUrl":"10.2344/24-0054","url":null,"abstract":"<p><p>The hyperosmolar hyperglycemic state (HHS) is an acute metabolic complication of diabetes mellitus type 2 (DMT2) and a life-threatening emergency. A 76-year-old man with DMT2 that was well controlled with oral medications underwent oral cancer surgery. Postoperatively, a surgical site infection and aspiration pneumonia developed, exacerbating the patient's diabetes. His blood glucose level increased to >500 mg/dL, and both dehydration and hyperosmolality were observed. His effective plasma osmolality exceeded 300 mOsm/kg and corrected serum sodium level was 159 mEq/L, which were suggestive of HHS. Because the leading cause of HHS is surgical site infection, emergency surgery was scheduled for infection control. Prior to general anesthesia, the patient received an infusion of 500 mL of normal saline and insulin. Awake intubation was performed after the administration of midazolam and fentanyl after which general anesthesia was induced. The patient tolerated the emergent procedure well, and his HHS resolved. As HHS can occur even in patients with adequately controlled DMT2, the signs and symptoms of HHS must be monitored carefully during the perioperative period.</p>","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"33-38"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976865/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to Commentary: Finsterer, J. Outcome of General Anesthesia With Remimazolam in a m.3243A>G Carrier. Anesthesia Progress. 2026;73(1):51. doi: 10.2344/25-0017.","authors":"Mie Ueda, Nobuhiro Tanaka, Yoshihiro Momota, Masahiko Kawaguchi","doi":"10.2344/25-0035","DOIUrl":"10.2344/25-0035","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"52"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976870/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcome of General Anesthesia With Remimazolam in a m.3243A>G Carrier.","authors":"Josef Finsterer","doi":"10.2344/25-0017","DOIUrl":"10.2344/25-0017","url":null,"abstract":"","PeriodicalId":94296,"journal":{"name":"Anesthesia progress","volume":"73 1","pages":"51"},"PeriodicalIF":0.0,"publicationDate":"2026-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12976876/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147370963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}