African health sciences最新文献_第7页

Malaria Control Programme in Nigeria: uptake of prevention strategies - a systematic review 尼日利亚疟疾控制计划：预防战略的采用情况--系统审查

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.21

Collins Ugwu, N. Ugwu, Ogbonnaya Ogbu, O. Chukwu, N. Chika-Igwenyi, Olaronke Afolabi, Daniel Igwe, Esther Ekwe, Ngozi Ezekwesili, C. Uneke, G. Isiguzo

{"title":"Malaria Control Programme in Nigeria: uptake of prevention strategies - a systematic review","authors":"Collins Ugwu, N. Ugwu, Ogbonnaya Ogbu, O. Chukwu, N. Chika-Igwenyi, Olaronke Afolabi, Daniel Igwe, Esther Ekwe, Ngozi Ezekwesili, C. Uneke, G. Isiguzo","doi":"10.4314/ahs.v24i2.21","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.21","url":null,"abstract":"Background: Malaria presents a colossal burden to Africa, including Nigeria. The objective of this study was to review relevant publications to identify specific malaria control strategies in Nigeria and to determine their level of uptake. \u0000Methods: A Medline Entrez Pubmed search was conducted to identify studies from July 2013 to June 2018 investigating malaria control strategies. The search yielded 123 publications and twelve publications that met the inclusion criteria were systematically reviewed and results presented. \u0000Results: Five publications investigated the level of uptake of IPTp-SP and all reported low uptake of IPTp-SP. Five other publications investigated the uptake of LLINs, of which two reported good uptake. Two studies were on the uptake of mRDT or microscopy before Artemesinin-based combination therapy (ACT) and reported good uptake. Factors associated with poor uptake of malaria preventive strategies included a poorly-financed and poorly structured healthcare system, poor antenatal clinic visits, unavailability of the antimalaria drugs and nets, ignorance, poverty, cultural/religious belief and cost of mRDT and microscopy. \u0000Conclusion: Though malaria control strategies are available in Nigeria, there was insufficient uptake of these preventive strategies. Awareness creation and education on the importance of preventive strategies and their efficient utilization will help reduce Nigeria’s malaria burden. \u0000Keywords: Anaemia; malaria control strategies; Nigeria; Uptake.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of preterm birth at St. Mary’s Hospital Lacor, Northern Uganda: a prospective cohort study 乌干达北部拉科尔圣玛丽医院早产预测：前瞻性队列研究

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.31

S. Awor, R. Byanyima, B. Abola, A. Nakimuli, Christopher Orach, P. Kiondo, Jasper Ogwal Okeng, Dan Kaye

{"title":"Prediction of preterm birth at St. Mary’s Hospital Lacor, Northern Uganda: a prospective cohort study","authors":"S. Awor, R. Byanyima, B. Abola, A. Nakimuli, Christopher Orach, P. Kiondo, Jasper Ogwal Okeng, Dan Kaye","doi":"10.4314/ahs.v24i2.31","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.31","url":null,"abstract":"Background: Preterm birth causes over 2% of perinatal mortality in Africa. Screening in prenatal clinics, may be used to identify women at risk. This study developed and validated second-trimester prediction models of preterm birth, using maternal socio-demographic characteristics, sonographic findings, and laboratory parameters in Northern Uganda. \u0000Methods: This prospective cohort study recruited 1,000 pregnant mothers at 16 - 24 weeks, and assessed their socio-demographic and clinical characteristics. Preterm birth (delivery after 28 and before 37 weeks) was the primary study outcome. Multi-variable analyses were performed, built models in RStudio, and cross-vaidated them using K (10)-fold cross-validation. \u0000Results: The Incidence of preterm birth was 11.9% (90 out of 774). The predictors of preterm birth were multiple pregnancies, personal history of preeclampsia, history of previous preterm birth, diastolic hypertension, serum ALP<98IU, white blood cell count >11000 cells/μl, platelet lymphocyte ratio >71.38, serum urea of 11-45 IU. These predicted preterm birth by 69.5% AUC, with 62.4% accuracy, 77.2% sensitivity, and 47.1% specificity. \u0000Conclusion: Despite low specificity, these models predict up to 77.2% of those destined to have a preterm birth, and may be used for second-trimester preterm birth screening in low-resource clinics. \u0000Keywords: Prediction; second-trimester; preterm-birth; Uganda; Africa.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"79 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between calcium-to-magnesium ratio and malaria parasite density among children with uncomplicated malaria infection 无并发症疟疾感染儿童的钙镁比值与疟原虫密度之间的关系

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.18

Oziegbe Johnson Airen, Loveth Amenaghawon Emokpae, Zainab Omoruyi, Mathias Abiodun Emokpae

{"title":"Relationship between calcium-to-magnesium ratio and malaria parasite density among children with uncomplicated malaria infection","authors":"Oziegbe Johnson Airen, Loveth Amenaghawon Emokpae, Zainab Omoruyi, Mathias Abiodun Emokpae","doi":"10.4314/ahs.v24i2.18","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.18","url":null,"abstract":"Background/Objective: A high calcium-to-magnesium ratio above 2:1 has been associated with higher risk of metabolic, inflammation and cardiovascular disorders. This study evaluates the serum levels of iron, magnesium, calcium, folate, vitamin B12 and calcium to magnesium ratio in children with uncomplicated malaria infection. \u0000Materials and Methods: Measured nutritional parameters were determined in 300 children (100 males and 100 females) with malaria infection and 100 children (50 males and 50 females) without malaria infection using Enzyme linked Immunosorbent Assay and spectrophotometric methods. \u0000Results: Significantly lower (p<0.001) levels of serum magnesium, iron, vitamin B12, folate and Packed cell volume (p<0.03) were observed among children with malaria than controls. On the other hand, serum calcium (8.45±0.20) and calcium-to-magnesium ratio (3.9:1.0) (were significantly higher (p<0.001) in malaria infected children than controls. Calcium to magnesium ratio correlated (r=0.188; p<0.01) with malaria parasitaemia. \u0000Conclusion: Higher serum calcium-to-magnesium ratio above the recommended 2.1 may contribute to increase risk of morbidity and mortality. Nutritional intervention aimed at lowering the ca/mg ratio may be essential in the management of malaria infection in Children. \u0000Keywords: Child; calcium; magnesium; parasites.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"117 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Virologic re-suppression and the associated factors among children aged 1-9 years on Antiretroviral Therapy in The Aids Support Organization Soroti Region, Uganda: a retrospective cohort analysis 乌干达索罗蒂地区艾滋病支持组织中接受抗逆转录病毒疗法的 1-9 岁儿童的病毒再抑制及相关因素：回顾性队列分析

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.2

Winfred Ruth Acham, Aisha Nalugya, Ricky Nyatia, Nelson Bunani

{"title":"Virologic re-suppression and the associated factors among children aged 1-9 years on Antiretroviral Therapy in The Aids Support Organization Soroti Region, Uganda: a retrospective cohort analysis","authors":"Winfred Ruth Acham, Aisha Nalugya, Ricky Nyatia, Nelson Bunani","doi":"10.4314/ahs.v24i2.2","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.2","url":null,"abstract":"Background: Children living with HIV experience low viral load re-suppression after a high viral load compared to the rest of the population. We determined the proportion with re-suppressed viral load and associated factors among children 1-9 years on Antiretroviral Therapy (ART) in The Aids Support Organization (TASO) Soroti Region. \u0000Methods: We conducted a retrospective cohort analysis of 401 records of children that initially had high viral load > 1000copies/ml for the period January 2016 to December 2018. Modified Poisson regression was performed to determine factors associated with virologic re-suppression. \u0000Results: The prevalence of virologic re-suppression was 97/401 (24.2%). More than half, 213 (53.1%) of the children were females and 197/401 (49%) were aged between 8 and 9 years. Factors associated with virologic re-suppression were; being on protease inhibitor (PI) based regimen [APR 2.87, 95% CI 1.76-4.79], good adherence [APR1.71, 95% CI 1.22-2.51] and caregiver HIV seropositive status [APR 2.56, 95% CI 1.69-3.91]. \u0000Conclusion: Virologic re-suppression was low compared to the UNAIDS target. Taking PI-based regimen, good adherence and HIV seropositive status of the caregiver were predictors of virologic re-suppression. Close viral load monitoring of children on ART and intensified targeted adherence support to caregivers is vital to improving virologic re-suppression. \u0000Keywords: Virologic re-suppression; Human Immunodeficiency Virus; children.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nurses' knowledge and attitude towards palliative care in Northcentral Ethiopia: a cross-sectional study 埃塞俄比亚中北部地区护士对姑息关怀的认识和态度：横断面研究

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.46

Tigabu Munye Aytenew, N. Ejigu, Melese Kebede, T. Amera, Amare Simegn, Tadila Dires, Demewoz Kefale, Solomon Demis, Gebrie Kassaw, Berihun Bantie

{"title":"Nurses' knowledge and attitude towards palliative care in Northcentral Ethiopia: a cross-sectional study","authors":"Tigabu Munye Aytenew, N. Ejigu, Melese Kebede, T. Amera, Amare Simegn, Tadila Dires, Demewoz Kefale, Solomon Demis, Gebrie Kassaw, Berihun Bantie","doi":"10.4314/ahs.v24i2.46","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.46","url":null,"abstract":"Background: Due to limited development of palliative care practice in Africa, many patients have not yet received formal palliative care. However, there were limited studies conducted among nurses assessing their knowledge and attitude towards palliative care in Ethiopia. \u0000Objective: The study aimed to assess nurses’ knowledge and attitude towards palliative care. \u0000Methods: A cross-sectional study was conducted, and a total of 402 were included in the study. A structured and pre-tested self-administered questionnaire was used to collect the data. Binary logistic regression was used to analyze the outcome variables. Finally, the association was declared using AOR at a 95% CI at p ≤0.05. \u0000Results: Of the total respondents, 216 (55.81%) were women. This study finding revealed that 304 (78.55%) of the respondents had inadequate knowledge, and 273 (70.54%) had unfavourable attitude towards palliative care. Educational level (AOR=2.61, 95%CI: 1.39, 4.89) and work experience (AOR=5.86, 95%CI:1.27, 26.92) were significantly associated with knowledge and attitude towards palliative care. \u0000Conclusions: This study finding showed that educational level and years of work experience showed a significant association with nurses’ knowledge and attitude towards palliative care. The concerned bodies and stake holders shall work together to enhance the nurses’ knowledge and attitude towards palliative care. \u0000Keywords: Knowledge; attitude; palliative care; nurses.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"132 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aflatoxins contamination in spices marketed in selected areas of Tanzania and their Detection by Chromatographic Technique 坦桑尼亚部分地区市场上销售的香料中的黄曲霉毒素污染及其色谱检测技术

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.17

Sharifa Juma, Clarence A Mgina, Kessy F Kilulya

{"title":"Aflatoxins contamination in spices marketed in selected areas of Tanzania and their Detection by Chromatographic Technique","authors":"Sharifa Juma, Clarence A Mgina, Kessy F Kilulya","doi":"10.4314/ahs.v24i2.17","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.17","url":null,"abstract":"Background: Aflatoxins are a family of toxins produced by fungi species known as Aspergillus flavus and Aspergillus parasiticus. Contamination of aflatoxins in agricultural crops is of high concern as it has negative effects on public health. \u0000Objective: This study reports on the levels of aflatoxins in four types of spices (black pepper, turmeric, cardamom and garlic) collected from markets, stores and farms in selected locations of Tanzania. \u0000Methods: A total of 84 samples of selected spices were collected. The determination of aflatoxins was performed using high-performance liquid chromatography, coupled with fluorescence detector. \u0000Results: The results obtained showed that 64 samples (76%) were contaminated with total aflatoxins at varying levels with respect to location and weather conditions. Mean concentrations of total aflatoxins ranged from < DL to 8.41 ngg-1 for black pepper, from < DL to 0.22 ngg-1 for garlic, from < DL to 11.07 ngg-1 for cardamom and from 0.28 to 2.21 ngg-1 for turmeric. 4.7% of samples exceeded the maximum tolerable limit of 10 ngg-1 for total aflatoxins (TAF) set by European Commission and 7 (8.33 %) samples exceeded the maximum tolerable limit of 5 ngg-1 for Aflatoxin B1. \u0000Conclusion: The observed aflatoxin contamination gives an alert for control of aflatoxins for improved public health. \u0000Keywords: Aflatoxins; mycotoxins; liquid chromatography; contamination; spices.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"130 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge, attitude and practices related to tuberculosis among patients at the Presbyterian Hospital in the Asante Akim North District 阿桑特-阿基姆北区长老会医院病人对结核病的认识、态度和做法

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.10

Sebastian Osei Kwarteng, Eric Sampane Donkor, Julius Eyiuche Nweze

{"title":"Knowledge, attitude and practices related to tuberculosis among patients at the Presbyterian Hospital in the Asante Akim North District","authors":"Sebastian Osei Kwarteng, Eric Sampane Donkor, Julius Eyiuche Nweze","doi":"10.4314/ahs.v24i2.10","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.10","url":null,"abstract":"Background: Tuberculosis (TB) is one of the major public health concerns in Ghana, with serious economic and social consequences. Tuberculosis is an infectious disease that is preventable and curable, as health educational programmes contribute to the control of TB However, the evidence required for such programmes is lacking in Ghana. \u0000Objectives: The aim of this study was to examine the underlying practices, attitudes and knowledge (PAK) of the patients at the Presbyterian hospital in Agogo, the Asante Akim North District (PHAA-AND) about tuberculosis disease and healthcare-seeking behaviour. \u0000Methods: This was a cross-sectional study among patients in the PHAA-AND. A simple random sampling method was used in selecting 370 participants for the study, who were interviewed regarding their TB knowledge, attitude and infection control practices. \u0000Results: Our study shows that the majority of the respondents demonstrated good knowledge about TB regarding its causative agent (68%), transmission (85.6%) and prevention (81.7%). However, poor knowledge was expressed regarding TB treatment by the majority (80.8%) of the respondents. Generally, the majority of respondents had a positive attitude and expressed good infection control practices regarding TB. The strongest determinants of TB related knowledge, or attitude or towards infection control practices were; level of education (OR, 1.49, CI; 1.25-1.77, p < 0.001), and gender (OR, 0.37, CI; 0.21-0.69, p=0.001). \u0000Conclusions: Respondents had good PAK towards TB, though some gaps were identified. These gaps called for health education about TB in the study area, and effective educational programs. \u0000Keywords: Knowledge; attitude; practices; tuberculosis; Presbyterian Hospital in the Asante Akim North District.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"1 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postnatal neonatal outcomes of a targeted mobile phone intervention use in antenatal care amongst pregnant women in a pastoralist community in narok county, Kenya: a randomized control trial 肯尼亚纳罗克县一个牧民社区的孕妇在产前护理中使用定向手机干预的产后新生儿结局：随机对照试验

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.26

D. Muvengei, Simon Karanja, P. Wanzala

{"title":"Postnatal neonatal outcomes of a targeted mobile phone intervention use in antenatal care amongst pregnant women in a pastoralist community in narok county, Kenya: a randomized control trial","authors":"D. Muvengei, Simon Karanja, P. Wanzala","doi":"10.4314/ahs.v24i2.26","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.26","url":null,"abstract":"Background: Complications in pregnancy, at childbirth and the pueperium cause high mortality and morbidity among women and neonates globally especially in the Lower and Middle Income Countries. Antenatal care is a key high impact strategy to improve maternal and child health. The objective of the study was to examine the effects of a targeted mobile phone intervention use in the provision of antenatal care on attendance and subsequent postnatal outcomes among pregnant women in a pastoralist community. \u0000Methods: We conducted a Randomized Controlled Trial (RCT) in four hospitals in Narok County, Kenya. Pregnant women were recruited early in pregnancy and followed upto 42 days after delivery. Recruitment started in June 2018. There were two study groups; the intervention and non-intervention groups with the non-intervention group receiving the routine care. \u0000Results: Two-hundred-and-sixty-two of the 280 study participants completed the study (93.6% response rate). The difference in proportion of study participants who had neonatal mortality at birth between the two study arms was 9.32% (95% CI 1.91-16.74%) between the intervention (6.06%) and the non-intervention (15.38%) study arms (p value = 0.015). \u0000Conclusion: A targeted mobile phone intervention used in antenatal care was associated with improved antenatal care attendance and better neonatal outcomes. \u0000Keywords: Postnatal neonatal outcomes; targeted mobile phone intervention; use in antenatal care amongst pregnant women; in a pastoralist community in Narok county; Kenya.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"46 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

TB co-infection and associated factors among HIV patients attending highly active antiretroviral therapy in Saint Peter’s TB Specialized Hospital, Ethiopia: a five years retrospective study 埃塞俄比亚圣彼得结核病专科医院接受高效抗逆转录病毒治疗的艾滋病患者中的结核病合并感染及相关因素：一项为期五年的回顾性研究

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.7

Dereje Getaw, F. Tigu

{"title":"TB co-infection and associated factors among HIV patients attending highly active antiretroviral therapy in Saint Peter’s TB Specialized Hospital, Ethiopia: a five years retrospective study","authors":"Dereje Getaw, F. Tigu","doi":"10.4314/ahs.v24i2.7","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.7","url":null,"abstract":"Background: TB and HIV are the two widely distributed and successful microbial diseases which impose public health problems globally. \u0000Objectives: The study aimed to determine the prevalence and associated factors of TB among people living with HIV (PLHIV). \u0000Methods: A retrospective study was conducted among PLHIV at Saint Peter’s TB Specialized Hospital (SPTSH). Study participants were selected by random sampling technique. Logistic regression analyses were employed to determine the associations between dependent and independent variables. P ≤ 0.05 was taken as statistically significant. \u0000Results: The prevalence of TB among PLHIV in the entire study population was 24.6%. The proportion of pulmonary TB (PTB), disseminated TB (DTB) and extra pulmonary TB (EPTB), were 49 (57.6%), 9 (10.6%) and 27 (31.8%), respectively. Logistic regression analysis showed that PLHIV who are non-adhered to ART (AOR = 51.6, 95% CI 24.18 - 387), HAART duration of > 35 months (AOR = 0.39, 95% CI 0.198 - 2.10) and WHO clinical stage IV (AOR = 40.14, 95% CI15.14 -106.44), were significantly associated with TB/HIV co-infection. \u0000Conclusions: TB co-infection is the major public health issue of PLHIV. Special emphasis is required to reduce the incidence of TB/HIV associated morbidity and mortality among PLHIV. \u0000Keywords: Adherence; ETB; prevalence; TB/HIV co-infection.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"72 s320","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141835237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of COVID-19 pandemic in tuberculosis diagnosis in sub-Saharan Africa: data from DREAM program in Mozambique COVID-19 大流行对撒哈拉以南非洲结核病诊断的影响：莫桑比克 DREAM 计划的数据

African health sciences Pub Date : 2024-07-11 DOI: 10.4314/ahs.v24i2.11

F. Ciccacci, Kanyza Ibraimo, A. Sineque, Susanna Ceffa, Zita Sidumo, Stefano Orlando, Cristina Marazzi

{"title":"The impact of COVID-19 pandemic in tuberculosis diagnosis in sub-Saharan Africa: data from DREAM program in Mozambique","authors":"F. Ciccacci, Kanyza Ibraimo, A. Sineque, Susanna Ceffa, Zita Sidumo, Stefano Orlando, Cristina Marazzi","doi":"10.4314/ahs.v24i2.11","DOIUrl":"https://doi.org/10.4314/ahs.v24i2.11","url":null,"abstract":"Background: TB is a global emergency, COVID-19 reversed the trend in TB mortality reduction to 2017 levels. Mozambique is one of the highest-burden countries with 368 new cases per 100.000 population in 2020.Objectives: This analysis aims to evaluate a TB diagnostic service in two Mozambican cities before and during the COVID-19 pandemic.Methods: We reviewed routine activity data from two laboratories in Mozambique (Maputo and Beira) in the period 01/2018–08/2022. GeneXpert test was prescribed based on clinical suspicion. Data about the number of tests, results, and rifampicin resistance were collected.Results: In the period 3,071 tests were conducted: 391 positive, and 32 rifampicin resistant. The number of positive samples was higher in Beira (20.2% vs 5%, OR 4[3.1-5.2]).In Maputo, we observed a higher percentage of rifampicin-resistant samples (13.2%vs7%, OR 0.5[0.2-1.1]), but the overall prevalence of rifampicin resistance was higher in Beira (14.1‰vs6.6‰, OR 2.1[1.0-4.5]).In 2020 and the first semester of 2021 a reduction in activity was observed, but positivity rates remained stable, with a slight increment starting in 2020.Conclusions: Our data confirm the impact of the COVID-19 pandemic on TB diagnostic services but also highlight possible benefits in terms of diagnostic appropriateness in clinical centers.Keywords: COVID-19 pandemic; tuberculosis diagnosis; sub-Saharan Africa; Mozambique.","PeriodicalId":94295,"journal":{"name":"African health sciences","volume":"40 2‐3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141834900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0