Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy最新文献
{"title":"Plasmapheresis as rescue therapy for steroid-resistant isolated optic neuritis: A case report.","authors":"Eiman Abdel Wahab Fayez Hussein, Mohamed Hussein","doi":"10.1111/1744-9987.70034","DOIUrl":"10.1111/1744-9987.70034","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"800-801"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144062351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Beyza Doğan, Fatih Ergül, Mikail Dağ, Süleyman Karaköse, İbrahim Güney
{"title":"The Effect of Arteriovenous Fistula Creation on GFR Decline.","authors":"Beyza Doğan, Fatih Ergül, Mikail Dağ, Süleyman Karaköse, İbrahim Güney","doi":"10.1111/1744-9987.70054","DOIUrl":"10.1111/1744-9987.70054","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic kidney disease (CKD) poses a significant public health challenge, severely affecting patients' quality of life. The Kidney Disease Outcomes Quality Initiative (KDOQI) guidelines recommend discussing renal replacement therapy options when patients reach CKD stage 4. Arteriovenous fistula (AVF) creation is considered the gold standard for vascular access in hemodialysis. This retrospective study aims to evaluate whether any changes in kidney function occur during the follow-up period after AVF creation in patients with end-stage kidney disease (ESKD).</p><p><strong>Methods: </strong>We analyzed data from 60 CKD patients who underwent AVF creation and were monitored in our nephrology outpatient clinics. Seventeen patients who consistently attended follow-up visits were included for detailed analysis. We performed a retrospective review of laboratory and medical records from 6 months before and 6 months following AVF creation.</p><p><strong>Results: </strong>The cohort comprised 41.2% males, with a mean age of 62.4 years. The predominant underlying conditions were diabetes mellitus (58.8%), hypertension (29.4%), and polycystic kidney disease (11.8%). Statistical analysis of laboratory values before and after AVF creation (at 1, 3, and 6 months) revealed a significant decline in estimated glomerular filtration rate (eGFR) before AVF placement, followed by stabilization in the subsequent 6 months.</p><p><strong>Conclusion: </strong>The rate of eGFR decline was significantly reduced in CKD patients with AVF. This may be attributed to increased awareness of impending hemodialysis, leading to better dietary adherence and treatment compliance.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"747-751"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: Clinical efficacy of low molecular weight heparin and insulin combined with plasma exchange in treating hyperlipidemic acute pancreatitis: A randomized controlled study.","authors":"Muhammad Farhan Khan, Hina Khan, Faraz Iqbal","doi":"10.1111/1744-9987.70029","DOIUrl":"10.1111/1744-9987.70029","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"798-799"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144036475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ionized Calcium Before Venous Bubble Trap Strongly Affects Coagulation When Using Calcium-Containing Dialysate in Regional Citrate Anticoagulation for Intermittent Hemodialysis: A Real-World Prospective Study.","authors":"Zhen Ai, Lijun Luo, Wenhao Li, Haishan Wu, Lian Zhao, Raoping Wang, Dihua Zhang, Suiqin Wen, Yuanwen Xu","doi":"10.1111/1744-9987.70055","DOIUrl":"10.1111/1744-9987.70055","url":null,"abstract":"<p><strong>Introduction: </strong>Regional citrate anticoagulation (RCA) is highly recommended as an anticoagulation method for intermittent hemodialysis (IHD) in patients at high bleeding risk. Few studies have investigated the effect of ionized calcium (iCa) concentration at different pipeline points on circuit clotting in RCA using calcium-containing dialysate.</p><p><strong>Methods: </strong>This prospective study included 185 IHD sessions treated with a two-stage RCA protocol. Ionized calcium levels were measured at different pipeline points. The primary endpoint was severe clotting in the extracorporeal circulation circuit (ECC).</p><p><strong>Results: </strong>Sessions with severe circuit clotting showed higher platelet counts, shorter activated partial thromboplastin time, greater dialyzer surface areas, and higher iCa concentrations around venous bubble trap (VBT). Cox regression models revealed that iCa concentration before VBT (per 0.10 mmol/L, hazard ratio (HR) = 1.54, p = 0.006) and baseline platelet count (HR = 1.01, p = 0.02) were strongly associated with severe circuit clotting.</p><p><strong>Conclusion: </strong>The iCa concentration before VBT could serve as a key indicator of anticoagulant efficacy in RCA with calcium-containing dialysate.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"730-738"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144311148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Peritoneal Lavage With Low GDP Neutral pH PD Solution Reduces Mortality and Severity in a Lethal Peritonitis Model.","authors":"Masato Ikeda, Kotaro Haruhara, Yukio Maruyama, Naoko Tanaka, Risa Kusanagi, Yuri Sakamaki, Hitomi Hagiwara, Takashi Yokoo","doi":"10.1111/1744-9987.70061","DOIUrl":"10.1111/1744-9987.70061","url":null,"abstract":"<p><strong>Introduction: </strong>The efficacy of peritoneal lavage monotherapy using PD solution for severe peritonitis remains unproven.</p><p><strong>Methods: </strong>We evaluated the effects of 3-times and 6-times lavage using low GDP neutral PD solution on a Methicillin-sensitive Staphylococcus aureus (MSSA) lethal peritonitis model rats without antibiotic use. Changes in effluent viable bacteria numbers dependent on lavage frequency were determined in a further 10 rats.</p><p><strong>Results: </strong>Compared to the lethal peritonitis model without lavage, both 3-times and 6-times lavage significantly reduced 24-h mortality, effluent FDP and creatinine concentrations. Furthermore, 6-times lavage significantly prevented the rough fur development, intraabdominal adhesion, and pus formation which developed in both the 0-times and 3-times lavage groups. The effluent viable bacterial counts showed significant step-ladder decreases with an increasing number of the lavages.</p><p><strong>Conclusion: </strong>We demonstrated for the first time that lavage monotherapy using PD solution reduces mortality and severity in a lethal peritonitis model by rapidly eliminating bacteria without antibiotic use.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"752-759"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411685/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Real-World Practice and Challenges of Donor Lymphocyte Apheresis and Infusion: A Single-Center Experience.","authors":"Shuhei Kurosawa, Kyoko Haraguchi, Yuho Najima, Yusuke Uchibori, Moemi Ishiwada, Yunoka Honma, Fuyuko Kawai, Rei Watanabe, Ryoko Iimura, Sayuri Ishibashi, Kae Sakuma, Kiyomi Narishima, Misako Nishimura, Fumihiko Ouchi, Masashi Shimabukuro, Atsushi Jinguji, Takashi Toya, Hiroaki Shimizu, Noriko Doki, Yoshiki Okuyama","doi":"10.1111/1744-9987.70053","DOIUrl":"10.1111/1744-9987.70053","url":null,"abstract":"<p><strong>Background: </strong>Although donor lymphocyte infusion (DLI) is a treatment option after posttransplant immunomodulation, data on donor lymphocyte apheresis (DLA) remain scarce.</p><p><strong>Methods: </strong>We retrospectively analyzed 26 recipients receiving DLI and their related donors (human leukocyte antigen [HLA]-matched, n = 9; haploidentical, n = 17).</p><p><strong>Results: </strong>The median harvested CD3-positive cell count (CD3) was 6.71 × 10<sup>7</sup> cells/kg (range, 3.55-19.74). A positive correlation was observed between harvested CD3 and preharvest lymphocyte counts (correlation coefficients = 0.78). In HLA-matched DLI, the median infused CD3 was 1.19 × 10<sup>7</sup> per cycle and 4.56 × 10<sup>7</sup> cells/kg in total; in haploidentical DLI, 0.25 × 10<sup>7</sup> and 0.44 × 10<sup>7</sup>, respectively. The proportion of total infused CD3 relative to harvested CD3 was 26.3% (range, 2.7-100) in HLA-matched DLI and 4.5% (range, 1.4-26.0) in HLA-haploidentical DLI. [Correction added on 21 June 2025, after first online publication: The minimum and maximum value of range for infused CD3 proportion in HLA-matched DLI and HLA-haploindentical DLI has been corrected in this version.] CONCLUSIONS: Our findings reflect real-world practices and underscore the importance of tailoring DLA to donor and recipient characteristics, particularly in light of the increasing use of haploidentical donors.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"782-791"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biomarkers Related to Peritoneal Transfer Function and Dialysis Adequacy.","authors":"Shuyi Pu, Shiyi Song, Xiaomin Jia, Ji Wang","doi":"10.1111/1744-9987.70052","DOIUrl":"10.1111/1744-9987.70052","url":null,"abstract":"<p><p>The main treatment for end-stage renal disease (ESRD) is renal replacement therapy, among which peritoneal dialysis (PD) is easy to perform, inexpensive, and widely used. The internationally adopted Peritoneal Equilibration Test (PET) categorizes peritoneal function into four types based on the dialysate-to-plasma creatinine ratio (D/Pcr). In some patients undergoing long-term PD, changes in peritoneal function lead to a decline in dialysis adequacy, which ultimately results in withdrawal from PD. Among these patients, those with high-transport peritoneal function exhibit higher mortality rates and poorer prognoses compared to patients with low-transport peritoneal function. However, PET fails to identify underlying pathologies (e.g., fibrosis, inflammation). Similarly, dialysis adequacy tests also fail to reveal the underlying causes of changes in dialysis adequacy. Therefore, early identification of the underlying causes of peritoneal function changes and timely clinical interventions may prolong the duration of PD. This review lists biomarkers related to peritoneal transport function that may indicate the causes of altered peritoneal function and could guide clinical treatment protocols in the future.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"713-720"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144287642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intermittent standing as a novel approach to alleviate intradialytic muscle cramps: A case report.","authors":"Subrahmanian Sathiavageesan","doi":"10.1111/1744-9987.70035","DOIUrl":"10.1111/1744-9987.70035","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"794-795"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Practical indications and the clinical outcomes of 21 cases of secondary embedding of peritoneal dialysis catheters.","authors":"Tsutomu Sakurada, Shohei Yamada, Shigeki Kojima","doi":"10.1111/1744-9987.70032","DOIUrl":"10.1111/1744-9987.70032","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"796-797"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blindness in a hemodialysis patient with right brachiocephalic vein stenosis reversed with recanalization.","authors":"Jaya Janardhan Jeeja, Kandula Venkata Koti Reddy, Rapur Ram, Vishnubotla Siva Kumar","doi":"10.1111/1744-9987.70011","DOIUrl":"10.1111/1744-9987.70011","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"792-793"},"PeriodicalIF":1.2,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}