Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy最新文献_第10页

Experience With Performing Rheocarna Therapy via the Single-Needle Method for Treatment of Chronic Limb-Threatening Ischemia. 单针法施曲红疗法治疗慢性肢体缺血的体会。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-09 DOI: 10.1002/1744-9987.70161

Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto

{"title":"Experience With Performing Rheocarna Therapy via the Single-Needle Method for Treatment of Chronic Limb-Threatening Ischemia.","authors":"Yasutaka Yamauchi, Rie Tanaka, Reona Kawahira, Shingo Nabeta, Kouhei Naoi, Kazuhito Kitajima, Akira Wada, Tomonari Takagi, Norihiko Ohura, Akira Miyamoto","doi":"10.1002/1744-9987.70161","DOIUrl":"https://doi.org/10.1002/1744-9987.70161","url":null,"abstract":"Introduction: This study investigated the safety and efficacy of single-needle Rheocarna therapy for chronic limb-threatening ischemia (CLTI) with wounds.Methods: Six patients with CLTI involving ulcers unresponsive to revascularization underwent single-needle Rheocarna treatment. Changes in mean low-density lipoprotein cholesterol (LDL-C), fibrinogen, C-reactive protein (CRP), white blood cell (WBC) count, platelet count, blood flow, and wound improvement were compared between treatment initiation and completion.Results: The treatment never required discontinuation due to in-circuit coagulation or hypotension, and its safety was confirmed. After 10 treatment sessions, LDL-C and fibrinogen removal rates were 24.3% and 24.4%, respectively. Platelet, WBC, and CRP values did not change significantly over time. Blood flow increased during treatment and posttreatment. All patients experienced wound improvement and favorable clinical outcomes.Conclusion: Single-needle Rheocarna therapy is effective for wound healing in CLTI. If this method applies to nondialysis patients without arteriovenous fistulas, indications for Rheocarna therapy will likely expand.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148207450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adsorptive Membranes as a Potential Confounder in Comparisons of Diffusive Versus Convective CRRT for Acute Kidney Injury. 在弥漫性和对流CRRT治疗急性肾损伤的比较中，吸附膜作为一个潜在的混杂因素。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-09 DOI: 10.1002/1744-9987.70171

Minmin Wang

引用次数: 0

Multimodal Management of Anti-GBM Disease Complicated by Secondary Complement-Mediated Thrombotic Microangiopathy in a Patient Intolerant to Plasma Exchange: A Case Report. 抗gbm疾病并发继发性补体介导的血栓性微血管病变的多模式管理：一例不耐受血浆交换的患者报告。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-08 DOI: 10.1002/1744-9987.70172

Xiangyu Yang, Ping Guo, Lisha Ma, Shasha Chen, Wei Wang

{"title":"Multimodal Management of Anti-GBM Disease Complicated by Secondary Complement-Mediated Thrombotic Microangiopathy in a Patient Intolerant to Plasma Exchange: A Case Report.","authors":"Xiangyu Yang, Ping Guo, Lisha Ma, Shasha Chen, Wei Wang","doi":"10.1002/1744-9987.70172","DOIUrl":"https://doi.org/10.1002/1744-9987.70172","url":null,"abstract":"Background: Anti-glomerular basement membrane (anti-GBM) disease complicated by thrombotic microangiopathy (TMA) is rare and clinically challenging. In the setting of severe infection and active autoimmune disease, complement activation may reflect a secondary process rather than primary atypical hemolytic uremic syndrome (aHUS). Therapeutic plasma exchange (TPE) is standard therapy for anti-GBM disease, but alternative antibody removal strategies are required when TPE is not tolerated.Case presentation: We describe a 46-year-old female with anti-GBM disease who developed TMA with preserved ADAMTS13 activity (72.04%) and 2.3% schistocytes on peripheral smear. Soluble C5b-9 was elevated in the context of severe concurrent infection. TPE was discontinued due to intolerance (oxygen desaturation, fever, and dizziness). Seven sessions of protein A immunoadsorption (PAIA) were performed for selective antibody removal, and anti-GBM antibody levels decreased from > 400 to 20.80 RU/mL during treatment. Eculizumab was administered on Days 7, 14, and 30, for persistent complement activation. Hematologic and biochemical parameters stabilized and gradually improved during combined therapy.Conclusion: This case suggests that PAIA may represent a feasible alternative antibody removal strategy in anti-GBM disease intolerant to plasma exchange. In selected cases of secondary complement-mediated TMA with ongoing complement activation, short-term complement inhibition may contribute to disease stabilization; however, a definitive causal relationship cannot be established in a single case.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148207365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective Low-Density Lipoprotein Apheresis for Relapse Minimal Change Nephrotic Syndrome in an Adult Patient With Acute Kidney Injury and Pneumococcal Infection: A Case Report. 有效的低密度脂蛋白分离治疗复发微小改变肾病综合征的成人急性肾损伤和肺炎球菌感染：1例报告。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-04 DOI: 10.1002/1744-9987.70168

Miya Hiramatsu, Akihito Tanaka, Kazuhiro Furuhashi

引用次数: 0

The Effect of Melatonin on Sleep Quality in Hemodialysis Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. 褪黑素对血液透析患者睡眠质量的影响：随机对照试验的系统回顾和meta分析。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-02 DOI: 10.1002/1744-9987.70159

Ana Gabriely Sales da Silva, Mariana Veiga E Silva, Beatriz Castanha de Oliveira, Fernanda Wagner, Marcos Antonio Dias Vilela, Letícia Freitas de Aquino, Claudia Maria Costa de Oliveira

{"title":"The Effect of Melatonin on Sleep Quality in Hemodialysis Patients: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.","authors":"Ana Gabriely Sales da Silva, Mariana Veiga E Silva, Beatriz Castanha de Oliveira, Fernanda Wagner, Marcos Antonio Dias Vilela, Letícia Freitas de Aquino, Claudia Maria Costa de Oliveira","doi":"10.1002/1744-9987.70159","DOIUrl":"10.1002/1744-9987.70159","url":null,"abstract":"Background: Sleep disturbances are common in adults receiving hemodialysis and are linked to higher mortality risk. Melatonin improves sleep quality in several adult populations based on the Pittsburgh Sleep Quality Index (PSQI), but its benefit in hemodialysis remains unclear. This systematic review and meta-analysis evaluated melatonin's efficacy compared to placebo on sleep quality in adults undergoing hemodialysis.Methods: Randomized controlled trials published up to October 2025 were identified. Data were extracted and quality assessed per Cochrane guidelines. RevMan software was used for analysis.Results: Five trials (323 patients) were included. Melatonin improved the global PSQI compared with placebo. Sleep duration and sleep efficiency improved with low heterogeneity. Sleep disturbances improved, and sensitivity analysis preserved the effect despite initial high heterogeneity.Conclusions: Melatonin may improve sleep quality in adults receiving hemodialysis, although certainty remains limited. Further trials are needed to establish the optimal dose and duration.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Story-Based Digital Game to Reduce Anxiety and Improve Treatment Adherence in Patients Receiving Hemodialysis: A Cluster-Randomized Controlled Trial. 基于故事的数字游戏可以减少血液透析患者的焦虑并提高治疗依从性：一项随机对照试验。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-02 DOI: 10.1002/1744-9987.70162

Afra Calik Kus, Sıddıka Ersoy

{"title":"A Story-Based Digital Game to Reduce Anxiety and Improve Treatment Adherence in Patients Receiving Hemodialysis: A Cluster-Randomized Controlled Trial.","authors":"Afra Calik Kus, Sıddıka Ersoy","doi":"10.1002/1744-9987.70162","DOIUrl":"https://doi.org/10.1002/1744-9987.70162","url":null,"abstract":"Introduction: Patients receiving hemodialysis frequently experience anxiety and treatment non-adherence, which negatively impact clinical outcomes. Digital health interventions offer innovative opportunities to address these challenges during dialysis sessions.Methods: This cluster-randomized controlled trial included 40 patients receiving chronic hemodialysis (intervention n = 20, control n = 20). The intervention group played a story-based digital game once during hemodialysis; controls received standard care. Outcomes were assessed using validated scales for anxiety, adherence, and dietary knowledge at baseline, 2 weeks, and 1 month.Results: The intervention group demonstrated significant improvements in treatment adherence (p < 0.001), dietary knowledge (p = 0.002), and anxiety reduction (p < 0.001) compared with controls at both follow-ups. Participants reported high game engagement with minimal negative effects. No adverse events occurred.Conclusions: A single-session story-based digital game enhanced adherence, knowledge, and reduced anxiety in hemodialysis patients, demonstrating that brief, engaging digital tools can support dialysis care and promote behavioral change.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148152920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffusive Versus Convective Continuous Renal Replacement Therapy for Acute Kidney Injury: A Systematic Review and Meta-Analysis. 弥漫性与对流性连续肾替代治疗急性肾损伤：系统回顾和荟萃分析。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-01 Epub Date: 2026-02-19 DOI: 10.1002/1744-9987.70128

Fatima Masud, Abdul Rehman Arshad, Sohail Sabir

{"title":"Diffusive Versus Convective Continuous Renal Replacement Therapy for Acute Kidney Injury: A Systematic Review and Meta-Analysis.","authors":"Fatima Masud, Abdul Rehman Arshad, Sohail Sabir","doi":"10.1002/1744-9987.70128","DOIUrl":"10.1002/1744-9987.70128","url":null,"abstract":"Introduction: This review assesses whether the mode of solute clearance in continuous renal replacement therapy influences mortality and renal recovery.Methods: The protocol was registered with PROSPERO (CRD420251030433). PubMed, Cochrane Library, and LILACS databases were searched until April 24, 2025. Observational studies and randomized controlled trials comparing diffusive and convective strategies of continuous renal replacement therapy in patients with acute kidney injury were included. Risk of bias was assessed using Cochrane ROB 2 and ROBINS-I tools.Results: Thirteen studies with 1146 patients were included. Diffusive modality had no advantage over convective modality with regards to mortality in intensive care unit (RR = 1.04; 95% CI: 0.83, 1.30; p = 0.73), 28-day mortality (RR = 1.19, 95% CI: 0.89, 1.59; p = 0.25), renal recovery (RR = 1.07; 95% CI: 0.65, 1.75; p = 0.79), or the length of stay in intensive care unit (SMD = 0.16 days; 95% CI: -0.17, 0.49; p = 0.33). Filter clotting was 31% less frequent in diffusive modality (RR = 0.69; 95% CI: 0.58, 0.81; p < 0.001).Conclusion: Diffusive modalities of continuous renal replacement therapy are not different from convective modalities in terms of mortality and renal recovery. However, they have the advantage of a longer filter lifespan resulting from less frequent clotting.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"298-308"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Letter to "Incidence and Associated Factors for Post-Transplant Diabetes Mellitus (PTDM) After Kidney Transplant in PMK-KT Center: Single Center". 致“PMK-KT中心肾移植后糖尿病（PTDM）发病率及相关因素：单一中心”的信。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-01 Epub Date: 2026-01-05 DOI: 10.1002/1744-9987.70114

Cai-Li Wang, Ying-Rui Huang

引用次数: 0

Effectiveness of Sleep Education Interventions on Sleep Problems in Adults Receiving Hemodialysis: Systematic Review and Meta-Analysis. 睡眠教育干预对成人血液透析患者睡眠问题的有效性：系统回顾和荟萃分析。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-01 Epub Date: 2025-12-14 DOI: 10.1002/1744-9987.70103

Hatice Ceylan, Şefika Tuğba Yangöz

{"title":"Effectiveness of Sleep Education Interventions on Sleep Problems in Adults Receiving Hemodialysis: Systematic Review and Meta-Analysis.","authors":"Hatice Ceylan, Şefika Tuğba Yangöz","doi":"10.1002/1744-9987.70103","DOIUrl":"10.1002/1744-9987.70103","url":null,"abstract":"Introduction: Hemodialysis population commonly faces sleep problems. Sleep educational interventions are implemented to address these problems, yet evidence on their effectiveness is limited. This study aimed to evaluate the impact of sleep educational interventions on sleep problems in hemodialysis.Methods: Following Cochrane Guidelines and PRISMA 2020, 11 electronic databases were searched. Data synthesis was performed with Comprehensive Meta-analysis version 3.Results: This study examined six studies and revealed that sleep education significantly improved sleep quality, subjective sleep quality, sleep latency, sleep duration, sleep disturbance, and medium effect on sleep efficiency, with low to high quality of evidence. Subgroup analysis found no difference in sleep quality improvement between group and individual education methods or between using and not using educational materials. Additionally, three or fewer sessions were more effective than six in enhancing sleep quality.Conclusion: This meta-analysis revealed that sleep education interventions positively improve sleep-related problems.Trial registration: PROSPERO: CRD42024523225.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"277-297"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145759130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adsorption of Blood Creatinine on a Heparin-Functionalized Surface of Copper-Based Metal-Organic Frameworks. 肝素功能化铜基金属有机骨架表面对血肌酐的吸附。

IF 1.2

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy Pub Date : 2026-06-01 Epub Date: 2026-01-29 DOI: 10.1002/1744-9987.70122

Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan

{"title":"Adsorption of Blood Creatinine on a Heparin-Functionalized Surface of Copper-Based Metal-Organic Frameworks.","authors":"Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan","doi":"10.1002/1744-9987.70122","DOIUrl":"10.1002/1744-9987.70122","url":null,"abstract":"Introduction: Creatinine accumulation exacerbates outcomes in chronic kidney disease (CKD). To enhance creatinine removal and improve hemocompatibility, we developed heparin-functionalized copper-based metal-organic frameworks (CuMOFs-Hep).Methods: CuMOFs were heparinized via APTES bridging and characterized (XRD, SEM, FTIR, XPS, and zeta potential). Adsorption was evaluated in simulated CKD serum and was fitted with isotherm models. Whole-blood samples from patients/healthy donors were tested. Biosafety was assessed by Cu2+ leaching and platelet assays.Results: Heparinization increased surface negative charge and raised the maximum capacity to 267.8 mg g-1 (68.7% over pristine; Langmuir R 2 = 0.983). Adsorption kinetics studies indicate rapid clearance of creatinine, achieving a clearance rate of 65.9% within 30 min at 37°C and reaching 75.0% within 2 h. In patient blood (854.2 μmol/L), supernatant creatinine decreased to 163.2 μmol/L (80.9% removal). Cu2+ leaching dropped to 0.214 ppm (-89.9%), with reduced platelet adhesion/activation.Conclusion: CuMOFs-Hep enables efficient, low-leaching creatinine adsorption in clinically relevant matrices, highlighting its promising potential as an efficient adsorbent for blood purification applications.","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"363-370"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0