Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy最新文献
{"title":"Diffusive Versus Convective Continuous Renal Replacement Therapy for Acute Kidney Injury: A Systematic Review and Meta-Analysis.","authors":"Fatima Masud, Abdul Rehman Arshad, Sohail Sabir","doi":"10.1002/1744-9987.70128","DOIUrl":"10.1002/1744-9987.70128","url":null,"abstract":"<p><strong>Introduction: </strong>This review assesses whether the mode of solute clearance in continuous renal replacement therapy influences mortality and renal recovery.</p><p><strong>Methods: </strong>The protocol was registered with PROSPERO (CRD420251030433). PubMed, Cochrane Library, and LILACS databases were searched until April 24, 2025. Observational studies and randomized controlled trials comparing diffusive and convective strategies of continuous renal replacement therapy in patients with acute kidney injury were included. Risk of bias was assessed using Cochrane ROB 2 and ROBINS-I tools.</p><p><strong>Results: </strong>Thirteen studies with 1146 patients were included. Diffusive modality had no advantage over convective modality with regards to mortality in intensive care unit (RR = 1.04; 95% CI: 0.83, 1.30; p = 0.73), 28-day mortality (RR = 1.19, 95% CI: 0.89, 1.59; p = 0.25), renal recovery (RR = 1.07; 95% CI: 0.65, 1.75; p = 0.79), or the length of stay in intensive care unit (SMD = 0.16 days; 95% CI: -0.17, 0.49; p = 0.33). Filter clotting was 31% less frequent in diffusive modality (RR = 0.69; 95% CI: 0.58, 0.81; p < 0.001).</p><p><strong>Conclusion: </strong>Diffusive modalities of continuous renal replacement therapy are not different from convective modalities in terms of mortality and renal recovery. However, they have the advantage of a longer filter lifespan resulting from less frequent clotting.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"298-308"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to \"Incidence and Associated Factors for Post-Transplant Diabetes Mellitus (PTDM) After Kidney Transplant in PMK-KT Center: Single Center\".","authors":"Cai-Li Wang, Ying-Rui Huang","doi":"10.1002/1744-9987.70114","DOIUrl":"10.1002/1744-9987.70114","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"436-437"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145907243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effectiveness of Sleep Education Interventions on Sleep Problems in Adults Receiving Hemodialysis: Systematic Review and Meta-Analysis.","authors":"Hatice Ceylan, Şefika Tuğba Yangöz","doi":"10.1002/1744-9987.70103","DOIUrl":"10.1002/1744-9987.70103","url":null,"abstract":"<p><strong>Introduction: </strong>Hemodialysis population commonly faces sleep problems. Sleep educational interventions are implemented to address these problems, yet evidence on their effectiveness is limited. This study aimed to evaluate the impact of sleep educational interventions on sleep problems in hemodialysis.</p><p><strong>Methods: </strong>Following Cochrane Guidelines and PRISMA 2020, 11 electronic databases were searched. Data synthesis was performed with Comprehensive Meta-analysis version 3.</p><p><strong>Results: </strong>This study examined six studies and revealed that sleep education significantly improved sleep quality, subjective sleep quality, sleep latency, sleep duration, sleep disturbance, and medium effect on sleep efficiency, with low to high quality of evidence. Subgroup analysis found no difference in sleep quality improvement between group and individual education methods or between using and not using educational materials. Additionally, three or fewer sessions were more effective than six in enhancing sleep quality.</p><p><strong>Conclusion: </strong>This meta-analysis revealed that sleep education interventions positively improve sleep-related problems.</p><p><strong>Trial registration: </strong>PROSPERO: CRD42024523225.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"277-297"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145759130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan
{"title":"Adsorption of Blood Creatinine on a Heparin-Functionalized Surface of Copper-Based Metal-Organic Frameworks.","authors":"Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan","doi":"10.1002/1744-9987.70122","DOIUrl":"10.1002/1744-9987.70122","url":null,"abstract":"<p><strong>Introduction: </strong>Creatinine accumulation exacerbates outcomes in chronic kidney disease (CKD). To enhance creatinine removal and improve hemocompatibility, we developed heparin-functionalized copper-based metal-organic frameworks (CuMOFs-Hep).</p><p><strong>Methods: </strong>CuMOFs were heparinized via APTES bridging and characterized (XRD, SEM, FTIR, XPS, and zeta potential). Adsorption was evaluated in simulated CKD serum and was fitted with isotherm models. Whole-blood samples from patients/healthy donors were tested. Biosafety was assessed by Cu<sup>2+</sup> leaching and platelet assays.</p><p><strong>Results: </strong>Heparinization increased surface negative charge and raised the maximum capacity to 267.8 mg g<sup>-1</sup> (68.7% over pristine; Langmuir R <sup>2</sup> = 0.983). Adsorption kinetics studies indicate rapid clearance of creatinine, achieving a clearance rate of 65.9% within 30 min at 37°C and reaching 75.0% within 2 h. In patient blood (854.2 μmol/L), supernatant creatinine decreased to 163.2 μmol/L (80.9% removal). Cu<sup>2+</sup> leaching dropped to 0.214 ppm (-89.9%), with reduced platelet adhesion/activation.</p><p><strong>Conclusion: </strong>CuMOFs-Hep enables efficient, low-leaching creatinine adsorption in clinically relevant matrices, highlighting its promising potential as an efficient adsorbent for blood purification applications.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"363-370"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146088690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of Lupus on All-Cause, Cardiovascular, and Infection-Related Mortality Among Dialysis Patients: Okinawa Dialysis Study Registry.","authors":"Nanako Oshiro, Yukiko Hasuike, Kentaro Kohagura, Kunitoshi Iseki","doi":"10.1002/1744-9987.70117","DOIUrl":"10.1002/1744-9987.70117","url":null,"abstract":"<p><strong>Introduction: </strong>Lupus nephritis is one of the most serious complications of systemic lupus erythematosus (SLE) and can lead to end-stage kidney disease (ESKD). We aimed to assess the relative mortality risk associated with SLE among dialysis patients.</p><p><strong>Methods: </strong>This retrospective longitudinal cohort study included all dialysis patients in the Okinawa Dialysis Study 30 registry. Cox proportional hazard models were performed to assess mortality.</p><p><strong>Results: </strong>Of 5246 patients, 111 had ESKD secondary to SLE. Compared with ESKD patients secondary to other causes, those with SLE had significantly higher risk of death (HR 2.55, 95% CI 1.81-3.47, p < 0.0001), cardiovascular death (HR 1.94, 95% CI 1.13-3.33, p = 0.0158), and infection death (HR 4.21, 95% CI 2.40-7.37, p < 0.0001) after adjusting for age, era of dialysis initiation, and sex.</p><p><strong>Conclusion: </strong>SLE may be independently associated with an increased risk of death in dialysis patients.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"340-344"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146000412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of a Novel Calculation Tool for Mixed Replacement Therapy Using Fresh Frozen Plasma and Albumin for Therapeutic Plasma Exchange.","authors":"Yosuke Imamura, Yuto Nishiyama, Daisuke Katagiri","doi":"10.1002/1744-9987.70120","DOIUrl":"https://doi.org/10.1002/1744-9987.70120","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":"30 3","pages":"438-440"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147793695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan
{"title":"Adsorption of Blood Creatinine on a Heparin-Functionalized Surface of Copper-Based Metal-Organic Frameworks.","authors":"Zhenyu Gui, Xiaoda Yang, Hao Chen, Jing Zhuang, Ping Lan","doi":"10.1002/1744-9987.70119","DOIUrl":"10.1002/1744-9987.70119","url":null,"abstract":"<p><strong>Introduction: </strong>Creatinine accumulation exacerbates outcomes in chronic kidney disease (CKD). To enhance creatinine removal and improve hemocompatibility, we developed heparin-functionalized copper-based metal-organic frameworks (CuMOFs-Hep).</p><p><strong>Methods: </strong>CuMOFs were heparinized via APTES bridging and characterized (XRD, SEM, FTIR, XPS, zeta potential). Adsorption was evaluated in simulated CKD serum and was fitted with isotherm models. Whole-blood samples from patients/healthy donors were tested. Biosafety was assessed by Cu<sup>2+</sup> leaching and platelet assays.</p><p><strong>Results: </strong>Heparinization increased surface negative charge and raised the maximum capacity to 267.8 mg g<sup>-1</sup> (68.7% over pristine; Langmuir R <sup>2</sup> = 0.983). Adsorption kinetics studies indicate rapid clearance of creatinine, achieving a clearance rate of 65.9% within 30 min at 37°C and reaching 75.0% within 2 h. In patient blood (854.2 μmol/L), supernatant creatinine decreased to 163.2 μmol/L (80.9% removal). Cu<sup>2+</sup> leaching dropped to 0.214 ppm (-89.9%), with reduced platelet adhesion/activation.</p><p><strong>Conclusion: </strong>CuMOFs-Hep enables efficient, low-leaching creatinine adsorption in clinically relevant matrices, highlighting its promising potential as an efficient adsorbent for blood purification applications.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"345-352"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146055821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zeynep Pehlivan Köksal, Vacide Aşik Özdemir, Yağmur Akbal Demirci
{"title":"The Effect of Symptom Severity on Life Satisfaction and Happiness in Patients Receiving Chronic Hemodialysis Treatment: Descriptive and Cross-Sectional Research.","authors":"Zeynep Pehlivan Köksal, Vacide Aşik Özdemir, Yağmur Akbal Demirci","doi":"10.1002/1744-9987.70115","DOIUrl":"10.1002/1744-9987.70115","url":null,"abstract":"<p><strong>Introduction: </strong>It is known that patients receiving HD treatment experience many symptoms alone or in combination, negatively affecting their life satisfaction and happiness levels. This study was conducted to determine the effect of symptom severity on life satisfaction and happiness in patients receiving chronic hemodialysis treatment.</p><p><strong>Method: </strong>A descriptive and cross-sectional study was conducted between April and May 2023 with 239 patients receiving treatment in four hemodialysis centers in a province in northeastern Turkey. The data were collected by face-to-face interview technique using the \"Descriptive Information Form,\" \"Dialysis Symptom Index (DSI),\" \"Satisfaction with Life Scale (SWLS),\" and \"Happiness Scale (HS).\"</p><p><strong>Results: </strong>A statistically significant difference was found between gender, exercise status, and the presence of secondary disease and HS and DSI (p < 0.05). At the same time, a significant difference was found between marital status and the SWLS and HS and between income level and smoking status and the SWLS (p < 0.05). There was a significant relationship between DSI and SWLS and HS, and DSI had a predictive effect on life satisfaction and happiness scale ( <math> <semantics> <mrow><msubsup><mi>R</mi> <mtext>adjusted</mtext> <mn>2</mn></msubsup> <mo>:</mo> <mn>0.027</mn></mrow> </semantics> </math> , <math> <semantics> <mrow><msubsup><mi>R</mi> <mtext>adjusted</mtext> <mn>2</mn></msubsup> <mo>:</mo> <mn>0.085</mn></mrow> </semantics> </math> ).</p><p><strong>Conclusion: </strong>Symptom severity was below moderate, life satisfaction was reasonable, and happiness level was above average in patients receiving chronic hemodialysis treatment. A comprehensive assessment of multiple symptoms and effective symptom management is recommended in patients receiving hemodialysis.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"323-331"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145914509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Influencing Factors of Adherence to Phosphorus Control in Patients Receiving Peritoneal Dialysis With Hyperphosphatemia: A Latent Profile Analysis.","authors":"Hua Hua Ma, Caiping Zhao, Yongni Wang, Keqing Xiao, Xiaoqin Ma","doi":"10.1002/1744-9987.70125","DOIUrl":"10.1002/1744-9987.70125","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to identify latent classes of adherence for serum phosphorus control and their influencing factors among patients receiving Peritoneal Dialysis with hyperphosphatemia.</p><p><strong>Methods: </strong>This cross-sectional study using convenience sampling was conducted among patients receiving peritoneal dialysis with hyperphosphatemia between December 2024 and May 2025. Participants were assessed using the Phosphate Control Adherence Scale, Self-Efficacy Scale, and Family Care and Social Support Scale. Demographic and clinical data were also collected. Latent profile analysis (LPA) was used to identify adherence subgroups. Univariate analysis and multicollinearity diagnostics were performed, followed by binary logistic regression to determine predictors of adherence.</p><p><strong>Results: </strong>Blood phosphorus control adherence can be classified into two categories: the low-level medical adherence group, characterized by poor dietary self-control (19.93%), and the high-level medical adherence group, marked by effective medication adherence (80.07%). The results indicated that residence conditions, types of medication, and self-efficacy significantly influenced blood phosphorus control adherence among patients with various forms of PD hyperphosphatemia (all p < 0.05).</p><p><strong>Conclusion: </strong>Patients with hyperphosphatemia undergoing peritoneal dialysis exhibit heterogeneity in adherence to serum phosphorus control. This indicates that healthcare providers should identify the adherence characteristics of different patient groups at an early stage and implement targeted intervention strategies to enhance patients' adherence to serum phosphorus management.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"377-388"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146159861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Therapeutic Plasmapheresis in a Tertiary Pediatric Intensive Care Unit: A 10-Year Single-Center Experience.","authors":"Nuqba Mohinoor, Shehreyar Ahmad","doi":"10.1002/1744-9987.70130","DOIUrl":"10.1002/1744-9987.70130","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"442-443"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146230454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}