Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy最新文献
Şimal Köksal Cevher, Neşe Altınok Ersoy, Ezgi Çoşkun Yenigün, Mehmet Tuncay, Selim Turgay Arınsoy, Erdem Çankaya, Fatih Dede
{"title":"The impact of \"nurse-led education\" vs. \"nurse-led education plus peer support\" on patients' decision for peritoneal dialysis treatment in chronic kidney disease patients.","authors":"Şimal Köksal Cevher, Neşe Altınok Ersoy, Ezgi Çoşkun Yenigün, Mehmet Tuncay, Selim Turgay Arınsoy, Erdem Çankaya, Fatih Dede","doi":"10.1111/1744-9987.14248","DOIUrl":"10.1111/1744-9987.14248","url":null,"abstract":"<p><strong>Introduction: </strong>End-stage kidney disease patients face a critical decision regarding kidney replacement therapy options, which include kidney transplantation, hemodialysis, or peritoneal dialysis (PD). This study aims to evaluate the impact of nurse-led education (NE) alone vs. NE combined with peer support on the patients' decision over PD treatment in chronic kidney disease patients.</p><p><strong>Methods: </strong>The study was conducted between 2018 and 2020, and patients were prospectively followed for the years 2018-2020. A total of 238 patients were selected from 500 outpatient clinic patients based on inclusion criteria and the principle of voluntary participation. Among 238 patients, 112 patients who received NE plus peer support as well as NE. Generalized linear models (GLM) analysis was employed to investigate the influence of NE and NE plus peer support on the decision of PD by patients.</p><p><strong>Results: </strong>In the NE plus peer support group, 38% were aged 45-59, and 65% were male. Similarly, in the NE group, 38% were aged 45-59, and 60% were male. The study utilized GLM to analyze patients' decisions regarding the PD treatment. Model 1 examined the duration of NE plus peer support (Akaike Information Criterion [AIC] = 130.46, McFadden's pseudo-R-squared (ρ<sup>2</sup>) = 0.569), Model 2 focused on the duration of NE (AIC = 294.11, McFadden's ρ<sup>2</sup> = 0.011), Model 3 assessed the sufficiency of NE plus peer support (AIC = 142.98, McFadden's ρ<sup>2</sup> = 0.526), and Model 4 evaluated the sufficiency of NE alone (AIC = 296.53, McFadden's ρ<sup>2</sup> = 0.085).</p><p><strong>Conclusions: </strong>Education provided by nurse and supported by peer affects patients' decision of kidney replacement treatment. Through the implementation of effective peer education, healthcare providers can enable patients to make informed decisions that align with their personal values, preferences, and treatment objectives, thereby enhancing clinical outcomes and overall patient satisfaction.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"723-730"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142908166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuh-Shan Ho, Karim M Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I Kamal, Balázs Szamosfalvi, Tibor Fülöp
{"title":"A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024.","authors":"Yuh-Shan Ho, Karim M Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I Kamal, Balázs Szamosfalvi, Tibor Fülöp","doi":"10.1002/1744-9987.70154","DOIUrl":"10.1002/1744-9987.70154","url":null,"abstract":"<p><strong>Background: </strong>Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end-stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in the field of uremic toxins from 1991 to 2024.</p><p><strong>Methods: </strong>The data were retrieved from the Science Citation Index Expanded (SCI-EXPANDED) database. The study analyzed 2210 articles using various bibliometric indicators, including total publications (TP), average number of citations per publication (CPP <sub>2024</sub>), and the Y-index for author contributions. Publication trends were examined across countries, institutions, and authors. The analysis included document types, languages, Web of Science categories, and journals.</p><p><strong>Results: </strong>The study revealed a steady increase in uremic toxin research publications. Japan, the USA, and China remained the most productive countries, with Japan maintaining the highest output, while Belgium achieved the highest citation impact. Citations of uremic toxin-related research peaked 2 years following publication and plateaued after approximately 6 years. The research foci evolved, with CKD, ESKD, indoxyl sulfate, protein-bound solutes, and gut microbiota gaining prominence. Studies on oxidative stress, inflammation, metabolomics, and advanced adsorption-based toxin removal strategies increased markedly. International collaboration and interdisciplinary integration across nephrology, microbiology, and biochemistry correlated with higher citation performance and research visibility.</p><p><strong>Conclusion: </strong>This bibliometric study provides an in-depth analysis of uremic toxin research trends, identifies major contributors, and suggests future research priorities. The findings can inform future research directions, guide funding allocation, and strengthen global collaborative efforts towards improved management of toxin-related kidney disease.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":"627-640"},"PeriodicalIF":1.2,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147965904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yunhong Yu, Yonghe Yu, Meihua Li, Shunlin Li, Rong Zhang, Zhong Liu, Ling Li
{"title":"The Evolving Landscape of Extracorporeal Photopheresis in Immunotherapy: A Comprehensive Bibliometric and Topic Modeling Analysis (1995-2024).","authors":"Yunhong Yu, Yonghe Yu, Meihua Li, Shunlin Li, Rong Zhang, Zhong Liu, Ling Li","doi":"10.1002/1744-9987.70228","DOIUrl":"https://doi.org/10.1002/1744-9987.70228","url":null,"abstract":"<p><strong>Introduction: </strong>Extracorporeal photopheresis (ECP) is an established immunomodulatory therapy for graft-versus-host disease (GVHD) and cutaneous T-cell lymphoma and is increasingly investigated for immune-related adverse events (irAEs). However, its collaborative networks, thematic evolution, and translational evidence gaps remain poorly characterized.</p><p><strong>Methods: </strong>We analyzed 1268 ECP publications from the Web of Science Core Collection (1995-2024) using bibliometric analysis and Latent Dirichlet Allocation (LDA) topic modeling. Studies published after the search cutoff were considered only for clinical context.</p><p><strong>Results: </strong>The United States, Germany, and Italy led publication output. Mann-Kendall analysis identified a significant change point around 2015. LDA revealed six thematic domains: early research emphasized dermatologic applications and solid organ rejection, whereas recent work shifted toward acute GVHD management and immunoregulatory mechanisms. Topic 6 captured mechanistic research on apoptosis and regulatory T-cell-mediated immune tolerance. Contextual prospective evidence in GVHD and irAEs suggested corticosteroid-sparing activity and generally favorable tolerability, but was limited by small cohorts, heterogeneous schedules and endpoints, and few randomized comparisons.</p><p><strong>Conclusion: </strong>ECP has evolved into a broader immunomodulatory platform, whereas its use for irAEs remains investigational. Future research should prioritize multicenter randomized trials, pediatric-specific protocols, predictive biomarkers, long-term tumor-control follow-up in irAEs, and health-economic evaluation.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149077267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Critical Appraisal: \"Effectiveness of a Novel Low-Density Lipoprotein Apheresis Device Rheocarna in Patients Undergoing Hemodialysis With Chronic Limb-Threatening Ischemia: A Single-Center Retrospective Study\".","authors":"Mukawish Zahra, Ariba Azhar, Shehreyar Ahmad","doi":"10.1002/1744-9987.70226","DOIUrl":"https://doi.org/10.1002/1744-9987.70226","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149019347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Efficacy of Double Filtration Plasmapheresis in Severe Fever With Thrombocytopenia Syndrome: A Multicenter Retrospective Study.","authors":"Shuqin Sun, Hongsen Tian, Xia Li, Shuo Yang","doi":"10.1002/1744-9987.70222","DOIUrl":"https://doi.org/10.1002/1744-9987.70222","url":null,"abstract":"<p><strong>Introduction: </strong>Double filtration plasmapheresis (DFPP) effectively removes toxins and inflammatory cytokines and is widely used for critical illnesses. However, evidence supporting DFPP use in severe fever with thrombocytopenia syndrome (SFTS) is scarce.</p><p><strong>Methods: </strong>We enrolled 144 severe SFTS patients matched 1:1 into DFPP and control groups (72 patients per group). Baseline characteristics were balanced between groups. Oxygenation, hemodynamics, inflammatory cytokines, and clinical endpoints (ICU stay, ventilation duration, complications, ICU, and 30-day mortality) were compared.</p><p><strong>Results: </strong>The two matched groups showed comparable baseline characteristics. DFPP improved oxygenation and hemodynamic indices, suppressed inflammatory cytokines, shortened ICU stay (13 (9-18) vs16 (12-23) days, p = 0.001), mechanical ventilation duration (8 (6-11) vs. 10 (7-13) days, p = 0.002), and lowered ICU mortality (9 (12.50) vs. 20 (27.78), p = 0.018) and 30-day mortality (p = 0.01).</p><p><strong>Conclusions: </strong>DFPP alleviates clinical manifestations and improves prognosis in patients with severe SFTS.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148993459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cross-Sectional Associations of Visfatin and YKL-40 With Carotid Intima-Media Thickness in Peritoneal Dialysis: A 12-Month Prospective Cohort Study.","authors":"Beyza Hilal Kından, Taha Enes Cetin, Irem Pamuk, Omer Faruk Akcay, Saliha Yildirim, Halit Nahit Sendur, Mahi Nur Cerit, Sevim Gonen, Seriyye Allahverdiyeva, Ulver Derici, Galip Guz, Ozant Helvaci","doi":"10.1002/1744-9987.70221","DOIUrl":"https://doi.org/10.1002/1744-9987.70221","url":null,"abstract":"<p><strong>Background: </strong>Cardiovascular disease is the leading cause of mortality in peritoneal dialysis (PD) patients. We investigated the cross-sectional and longitudinal associations of visfatin, YKL-40, and adiponectin with carotid intima-media thickness (CIMT) over 12 months.</p><p><strong>Methods: </strong>In this 12-month prospective cohort study, 30 maintenance PD patients underwent serial serum biomarker assessment and bilateral CIMT measurement. Associations were evaluated using paired comparisons and correlation analyses.</p><p><strong>Results: </strong>Both right and left CIMT increased significantly over 12 months (p < 0.01). Visfatin increased, adiponectin decreased (both p < 0.001), whereas YKL-40 remained stable. Visfatin and YKL-40 showed significant positive correlations with CIMT, while adiponectin showed negative correlations. A strong positive visfatin-YKL-40 inter-correlation was observed (r = 0.659, p < 0.001), representing a novel finding, to our knowledge, in a dialysis population.</p><p><strong>Conclusions: </strong>CIMT increased significantly over 12 months in PD patients. Visfatin and YKL-40 showed consistent positive cross-sectional associations with CIMT, whereas adiponectin showed inverse associations and declined over time. Longitudinal biomarker-CIMT associations were limited, with baseline YKL-40 being the only biomarker associated with right-sided ΔCIMT. These exploratory findings suggest potential inflammatory pathways involved in vascular remodeling in PD and warrant validation in larger prospective studies.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148979137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Asahi Oshima, Yu Horiuchi, Takuya Matsumoto, Kazushige Ito, Scot Garg, Yoshinobu Onuma, Patrick W Serruys, Kengo Tanabe, Naobumi Mise
{"title":"Temporal Changes in Left Ventricular Ejection Fraction After Initiating Hemodialysis.","authors":"Asahi Oshima, Yu Horiuchi, Takuya Matsumoto, Kazushige Ito, Scot Garg, Yoshinobu Onuma, Patrick W Serruys, Kengo Tanabe, Naobumi Mise","doi":"10.1002/1744-9987.70220","DOIUrl":"https://doi.org/10.1002/1744-9987.70220","url":null,"abstract":"<p><strong>Introduction: </strong>Longitudinal changes in left ventricular ejection fraction (LVEF) after commencing hemodialysis and their prognostic implications remain poorly characterized.</p><p><strong>Methods: </strong>We studied 278 patients who started hemodialysis between 2010 and 2022, underwent echocardiography within 90 days, and had at least one follow-up study. LVEF trajectories were analyzed using linear mixed-effects models and locally weighted scatterplot smoothing. Mortality was assessed using baseline, 1-year landmark, and time-updated LVEF categories.</p><p><strong>Results: </strong>LVEF initially improved but then declined in the 32 patients with a baseline LVEF ≤ 40%, whereas it remained stable in those with a baseline LVEF > 40%. Baseline LVEF ≤ 40% was associated with higher mortality (adjusted HR: 2.97, 95% CI: 1.38-6.37), with mortality risk increasing if LVEF remained ≤ 40% at 1 year. Time-updated LVEF ≤ 40% was independently associated with mortality (adjusted HR: 4.41, 95% CI: 2.37-8.22).</p><p><strong>Conclusions: </strong>LVEF changes dynamically after initiation of hemodialysis, and serial assessments identify patients at higher risk of mortality.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148963801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Albumin-to-Non-High-Density Lipoprotein Cholesterol Ratio and Prevalent Coronary Artery Stenosis at Hemodialysis Initiation.","authors":"Hirohito Sugawara, Kiryu Yoshida, Dai Kitahara, Yuri Fukuzaki, Hiroki Mizuyama, Yoshinori Saito, Masanori Kato, Akiko Takeshima, Masahiro Yamamoto, Hidetoshi Ito, Norihiro Hashizume, Hidefumi Fujisawa, Suguru Shimazu, Masahiko Ochiai, Hiroaki Ogata","doi":"10.1002/1744-9987.70219","DOIUrl":"https://doi.org/10.1002/1744-9987.70219","url":null,"abstract":"<p><strong>Background: </strong>Coronary artery stenosis (CAS) is common at hemodialysis (HD) initiation, even in asymptomatic patients. Because malnutrition, inflammation, and dyslipidemia may contribute to coronary atherosclerosis in advanced kidney disease, we evaluated whether the albumin-to-non-high-density lipoprotein cholesterol ratio (ANHR) was associated with prevalent CAS and provided incremental information beyond the nutritional risk index for Japanese hemodialysis patients (NRI-JH).</p><p><strong>Methods: </strong>This single-center cross-sectional study included patients who initiated HD between 2015 and 2023 and underwent screening coronary computed tomography within ±30 days of HD initiation. CAS was defined as ≥ 75% stenosis on computed tomography or coronary angiography.</p><p><strong>Results: </strong>Among 255 patients, 124 (49%) had CAS. ANHR was lower in the CAS group [2.7 (2.2-3.4) vs. 3.1 (2.3-4.0)], whereas NRI-JH was higher [6 (4-8) vs. 4 (3-8)]. Adding ANHR to the model containing NRI-JH significantly improved the fit and the ANHR model had the lowest Akaike's information criterion (341.2). NRI-JH was associated with higher odds of CAS (OR 1.34, 95% CI 1.02-1.76; p = 0.036), whereas ANHR was associated with lower odds of CAS (OR 0.64, 95% CI 0.48-0.84; p = 0.002). In the combined model, ANHR remained associated with CAS (OR 0.67, 95% CI 0.50-0.89; p = 0.006).</p><p><strong>Conclusion: </strong>In patients initiating HD, lower ANHR was associated with prevalent CAS. However, the improvement in discrimination was modest and not statistically significant. ANHR may provide adjunctive information regarding prevalent CAS, but its clinical utility as a screening marker requires further validation.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148932389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Growing Role of Centrifugal Therapeutic Plasma Exchange in Japan.","authors":"Hitomi Otani, Naho Matsubara, Daisuke Katagiri","doi":"10.1002/1744-9987.70216","DOIUrl":"https://doi.org/10.1002/1744-9987.70216","url":null,"abstract":"","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148922337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xuelei Zhang, Xin Li, Shuoqiang Hu, Dongqi Song, Qiang Ma
{"title":"Elevated Non-Fasting Remnant Cholesterol Predicts All-Cause Mortality in Hemodialysis Patients.","authors":"Xuelei Zhang, Xin Li, Shuoqiang Hu, Dongqi Song, Qiang Ma","doi":"10.1002/1744-9987.70217","DOIUrl":"10.1002/1744-9987.70217","url":null,"abstract":"<p><strong>Introduction: </strong>Remnant cholesterol (RC) has been proposed as a mortality indicator in various populations; however, it remains unknown whether non-fasting RC can predict prognosis in patients undergoing hemodialysis (HD).</p><p><strong>Methods: </strong>This retrospective study enrolled 203 patients who underwent regular HD between May 2023 and May 2026. Patients were divided into four groups according to quartiles of non-fasting RC.</p><p><strong>Results: </strong>Cox proportional hazards models revealed that RC was an independent predictor of all-cause mortality (hazard ratio [HR], 2.26; 95% confidence interval [CI], 1.10-4.65). In a joint analysis using upper quartile cut-offs of RC and low-density lipoprotein cholesterol (LDL-C), the high RC/high LDL-C group had a significantly higher mortality risk (HR: 2.67; 95% CI: 1.51-4.72) compared with the reference group. Isolated elevation of either RC or LDL-C was not associated with an increased mortality risk.</p><p><strong>Conclusions: </strong>RC may be a useful predictor of all-cause mortality in patients undergoing HD.</p>","PeriodicalId":94253,"journal":{"name":"Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148914733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}