The International journal of developmental biology最新文献_第6页

Developmental Biology in Greece. 希腊的发育生物学。

The International journal of developmental biology Pub Date : 2022-01-01 DOI: 10.1387/ijdb.220039nz

N. Zagris

引用次数: 0

Aristotle (384-322 BC): the beginnings of Embryology. 亚里士多德(公元前384-322年):胚胎学的开端。

The International journal of developmental biology Pub Date : 2022-01-01 DOI: 10.1387/ijdb.220040nz

N. Zagris

{"title":"Aristotle (384-322 BC): the beginnings of Embryology.","authors":"N. Zagris","doi":"10.1387/ijdb.220040nz","DOIUrl":"https://doi.org/10.1387/ijdb.220040nz","url":null,"abstract":"Aristotle made important contributions to many fields-biology, physics, metaphysics, logic, ethics, rhetoric, psychology, aesthetics, poetry- that are now cultivated by specialized experts, but he never lost sight of the aim of unifying knowledge, of understanding the world as an organized whole. Aristotle was the first to combine wet, field biology with daring cosmological thinking. He is the father of natural history and the first embryologist known to history. Aristotle's classic treatises History of Animals/Περί ζῴων ἱστορίαι, and On the Generation of Animals/ Περί ζῴων γενέσεως \"enjoyed for more than fifteen hundred years an authority altogether without parallel\". Over the last four decades, the introduction of molecular techniques has gradually overturned the entire structure of the biological sciences. Biology, initially a science of inventory and classification in the hands of the 19th-century comparative naturalists, has become a science of codes and regulatory circuits. Aristotle was the first to codify laws of pure logic, and so he founded what is today known as ' proof theory' in mathematics. Aristotle was an inveterate collector and a classifier, the master scientist of his time. His main concern was to classify \"the ultimate furniture of the world\", under basic headings and categories, a powerful human strategy to organize knowledge for comprehension and action. This was part of Aristotle's attempt to create a theory of reality, one strongly opposed to Plato's otherworldly doctrine of the ideal 'forms'. To many generations of thinkers in the great era of Scholastic philosophy, Aristotle was known simply as \"The Philosopher\".","PeriodicalId":94228,"journal":{"name":"The International journal of developmental biology","volume":"14 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83441353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Intraflagellar transport 20 cilia-dependent and cilia-independent signaling pathways in cell development and tissue homeostasis. 鞭毛内运输:细胞发育和组织稳态中依赖和不依赖纤毛的信号通路。

IF 0.7

The International journal of developmental biology Pub Date : 2022-01-01 DOI: 10.1387/ijdb.220072fj

Fu-Chang Jin, Ming-Hui Zhou, Jing-Jing Chen, Yi Lin, Qi-Wei Zhang, Qiu-Xian Xu, Chang-Chun Zhang, Zhen-Gang Zhang

{"title":"Intraflagellar transport 20 cilia-dependent and cilia-independent signaling pathways in cell development and tissue homeostasis.","authors":"Fu-Chang Jin, Ming-Hui Zhou, Jing-Jing Chen, Yi Lin, Qi-Wei Zhang, Qiu-Xian Xu, Chang-Chun Zhang, Zhen-Gang Zhang","doi":"10.1387/ijdb.220072fj","DOIUrl":"https://doi.org/10.1387/ijdb.220072fj","url":null,"abstract":"Intraflagellar transport (IFT) is an essential condition for ciliogenesis. The primary cilia protrude like antennae and act as chemical or mechanical sensory organelles that coordinate specific receptor localization and signal transduction. IFT20 is the smallest molecule in IFT complex B, which is located in both the cilia and the Golgi complex. Recent studies have shown that IFT20 is a key molecule in multiple signaling pathways. Importantly, in the function of IFT20, signal transduction is not restricted to cilia, but is also involved in non-ciliary functions. Here we summarize current knowledge regarding IFT20-mediated signaling pathways and their relationship with cell development and tissue homeostasis, and analyse the cilia-dependent and cilia-independent mechanisms of IFT20 coordinated signaling pathways and potential crosstalk between the mechanisms. This review provides a comprehensive perspective on IFT20 coordinates signaling mechanisms in cell development and tissue homeostasis.","PeriodicalId":94228,"journal":{"name":"The International journal of developmental biology","volume":" ","pages":"333-347"},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40720126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The mesenchymal potential of trunk neural crest cells. 干神经嵴细胞间充质电位。

IF 0.7

The International journal of developmental biology Pub Date : 2022-01-01 DOI: 10.1387/ijdb.220032gc

Monica Alves Rodrigues-Da-Silva, Guilherme de Espindola da Silveira, Clarissa Reginato Taufer, Giordano Wosgrau Calloni

{"title":"The mesenchymal potential of trunk neural crest cells.","authors":"Monica Alves Rodrigues-Da-Silva, Guilherme de Espindola da Silveira, Clarissa Reginato Taufer, Giordano Wosgrau Calloni","doi":"10.1387/ijdb.220032gc","DOIUrl":"https://doi.org/10.1387/ijdb.220032gc","url":null,"abstract":"It has long been held that the main difference between cranial and trunk neural crest (CNC and TNC, respectively) was the potential of CNC to originate mesenchymal cell types, especially skeletogenic. This is an age-old question that continues to challenge researchers, even today. Unfortunately, to date, no consensus has concluded the extent of TNC mesenchymal potential, nor has a systematic review been conducted to organize current knowledge about this fascinating question. However, the number of studies related to this question have expanded and deepened considerably in the last few years thanks to several new different species of vertebrates employed, the generation of transgenic animal strains, the combination of cell markers, and also the improvement of cell culture conditions through the use of different substrates and signaling molecules. Therefore, this review summarizes the literature showing that TNCCs can generate a broad range of mesenchymal cell types, including skeletogenic. This potential can be unveiled by certain favorable in vitro conditions, but it also seems to be expressed in some animal structures in vivo, to which TNCCs contribute. We also present several works that offer a contrary view and do not detect any mesenchymal/skeletogenic contribution of TNCCs in vivo. Perhaps, it is the controversy itself that makes this subject even more exciting.","PeriodicalId":94228,"journal":{"name":"The International journal of developmental biology","volume":" ","pages":"317-331"},"PeriodicalIF":0.7,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40590251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Molecular characterization of the prostaglandin E receptor subtypes 2a and 4b and their expression patterns during embryogenesis in zebrafish. 斑马鱼胚胎发生过程中前列腺素E受体2a和4b亚型的分子特征及其表达模式

The International journal of developmental biology Pub Date : 2021-02-22 DOI: 10.1387/ijdb.210003w

Yongjun Han, Hongbo Chang, Hong Wu

{"title":"Molecular characterization of the prostaglandin E receptor subtypes 2a and 4b and their expression patterns during embryogenesis in zebrafish.","authors":"Yongjun Han, Hongbo Chang, Hong Wu","doi":"10.1387/ijdb.210003w","DOIUrl":"https://doi.org/10.1387/ijdb.210003w","url":null,"abstract":"The molecular expression profiles of zebrafish ep2a and ep4b have not been defined to-date. Phylogenetic trees of EP2a and EP4b in zebrafish and other species revealed that human EP4 and zebrafish EP4b were more closely related than EP2a. Zebrafish EP2a is a 281 amino acid protein with high identity to that of human (43%), mouse (44%), rat (43%), dog (44%), cattle (41%), and chicken (41%). Zebrafish EP4b encoded a precursor of 497 amino acids with high amino acid identity to that of mammals, including human (57%), mouse (54%), rat (55%), dog (55%), cattle (56%), and chicken (54%). Whole-mount in situ hybridization revealed that ep2a was robustly expressed in the anterior four somites at the 10-somites stages, but was absent in the somites at 19 hpf. It was observed again in the pronephric duct at 24 hpf, in the intermediate cell mass located in the trunk, and in the rostral blood island at 30 hpf. Ep2a was also expressed in the notochord at 48 hpf. During somitogenesis, ep4b was highly expressed in the eyes, somites, and the trunk neural crest. From 30 to 48 hpf, ep4b could be detected in the posterior cardinal vein and the neighboring ICM. From these data, we conclude that ep2a and ep4b are conserved in vertebrates and that the presence of ep2a and ep4b transcripts during developmental stages infers their role during early zebrafish larval development. In addition, the variable expression of the two receptor isoforms was strongly suggestive of divergent roles of molecular regulation.","PeriodicalId":94228,"journal":{"name":"The International journal of developmental biology","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73325440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SV40T reprograms Schwann cells into stem-like cells that can re-differentiate into terminal nerve cells. SV40T将雪旺细胞重编程为干细胞样细胞，可以重新分化为末梢神经细胞。

The International journal of developmental biology Pub Date : 2020-02-26 DOI: 10.21203/rs.2.24550/v1

Rui-fang Li, Guo-xin Nan, Dan Wang, Chang Gao, Juan Yang, T. He, Zhong-lin Zhang

{"title":"SV40T reprograms Schwann cells into stem-like cells that can re-differentiate into terminal nerve cells.","authors":"Rui-fang Li, Guo-xin Nan, Dan Wang, Chang Gao, Juan Yang, T. He, Zhong-lin Zhang","doi":"10.21203/rs.2.24550/v1","DOIUrl":"https://doi.org/10.21203/rs.2.24550/v1","url":null,"abstract":"BACKGROUND\u0000The specific effect of SV40T on neurocytes has been rarely investigated by the researchers. We transfected Schwann cells (SCs) that did not have differentiation ability with MPH 86 plasmid containing SV40T in order to explore the effects of SV40T on Schwann cells.\u0000\u0000\u0000METHODS\u0000SCs were transfected with MPH 86 plasmid carrying the SV40T gene and cultured in different media, as well as co-cultured with neural stem cells (NSCs). In our study, SCs overexpressing SV40T were defined as SV40T-SCs. The proliferation of these cells was detected by WST-1, and the expression of different biomarkers was analyzed by qPCR and immunohistochemistry.\u0000\u0000\u0000RESULTS\u0000SV40T induced the characteristics of NSCs, such as the ability to grow in suspension, form spheroid colonies and proliferate rapidly, in the SCs, which were reversed by knocking out SV40T by the Flip-adenovirus. In addition, SV40T upregulated the expressions of neural crest-associated markers Nestin, Pax3 and Slug, and down-regulated S100b as well as the markers of mature SCs MBP, GFAP and Olig1/2. These cells also expressed NSC markers like Nestin, Sox2, CD133 and SSEA-1, as well as early development markers of embryonic stem cells (ESCs) like BMP4, c-Myc, OCT4 and Gbx2. Co-culturing with NSCs induced differentiation of the SV40T-SCs into neuronal and glial cells.\u0000\u0000\u0000CONCLUSIONS\u0000SV40T reprograms Schwann cells to stem-like cells at the stage of neural crest cells (NCCs) that can differentiate to neurocytes.","PeriodicalId":94228,"journal":{"name":"The International journal of developmental biology","volume":"11 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84277330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Memoriam - Antony Durston.

The International journal of developmental biology Pub Date : 2020-01-01 DOI: 10.1387/ijdb.200236vn

M. Cohen, V. Nanjundiah, C. Weijer, K. Zhu

引用次数: 0

Chick midgut morphogenesis. 鸡中肠形态发生。

IF 0.7

The International journal of developmental biology Pub Date : 2018-01-01 DOI: 10.1387/ijdb.170325ct

Tyler R Huycke, Clifford J Tabin

引用次数: 21

A snail tale and the chicken embryo. 蜗牛故事和鸡胚。

IF 0.7

The International journal of developmental biology Pub Date : 2018-01-01 DOI: 10.1387/ijdb.170301mn

M Angela Nieto

引用次数: 5

From soil mechanics to chick development. 从土壤力学到小鸡发育。

IF 0.7

The International journal of developmental biology Pub Date : 2018-01-01 DOI: 10.1387/ijdb.180030LW

Lewis Wolpert

引用次数: 5