Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia最新文献

{"title":"[Pulmonary infection in a patient with adenocarcinoma: an uncommon pathogen in pleural fluid].","authors":"Elena Bruñas-Yanes, Silvia Campos-Gutiérrez, Sonal Varma-Bathia, Héctor Manuel González-Expósito, María Lecuona-Fernández","doi":"10.37201/req/142.2025","DOIUrl":"10.37201/req/142.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"169-171"},"PeriodicalIF":2.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071775/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Diagnosis of an atypical case of infective endocarditis: added value of molecular biology techniques].","authors":"Jose Carlos de Gracia-Diaz, Ana Madueño, María Del Mar Alonso-Socas, Beatriz Castro, Sonia García-Hernández, María Lecuona","doi":"10.37201/req/126.2026","DOIUrl":"10.37201/req/126.2026","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"151-153"},"PeriodicalIF":2.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071776/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rezafungin for the treatment of invasive candidiasis secondary to esophagogastric anastomotic leak: clinical success in a complex situation.","authors":"Agustín Estévez, Daniel Lalinde, Rafael Ramos, Patricia Piñeiro, Patricia Muñoz","doi":"10.37201/req/140.2025","DOIUrl":"10.37201/req/140.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"166-168"},"PeriodicalIF":2.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071771/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Implementation of the AWaRe classification in a paediatric hospital as a strategy to improve the quality of antibiotic prescribing].","authors":"Alicia Abril-Cabero, Esperanza Nieto-Mártil, Pablo Ciudad-Gutiérrez, Alejandra Merino-Pardo, Margarita Cuervas-Mons Vendrell","doi":"10.37201/req/138.2025","DOIUrl":"10.37201/req/138.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"163-165"},"PeriodicalIF":2.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071769/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Early virological failure with long-acting cabotegravir/rilpivirine: description of two cases].","authors":"María José Pena-López, Esteban Gabriel Torres-Martel, Sergio Santana-Baez, Xerach Bosch-Guerra","doi":"10.37201/req/128.2026","DOIUrl":"10.37201/req/128.2026","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"154-157"},"PeriodicalIF":2.2,"publicationDate":"2026-03-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071778/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147391989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Coexistence of primary central nervous system lymphoma and cerebral toxoplasmosis in a patient with advanced HIV infection and negative serology].","authors":"Javier Velasco-Montes, María Teresa Lista-Araujo, Isabel de-Fuentes-Corripio, Ane Barreras-García","doi":"10.37201/req/134.2025","DOIUrl":"10.37201/req/134.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"158-159"},"PeriodicalIF":2.2,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071768/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146204501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of a <i>bla</i>_KPC-2 carrying IncP-6 plasmid in <i>Aeromonas caviae</i> isolated from a clinical sample in a Spanish hospital.","authors":"Carlos González-Corralejo, Cristina García-Salguero, Mercedes Martínez-Rodríguez, Alberto Delgado-Iribarren García-Campero, Esther Culebras-López","doi":"10.37201/req/127.2025","DOIUrl":"10.37201/req/127.2025","url":null,"abstract":"<p><p>The emergence of carbapenemase-producing <i>Aeromonas</i> species represents a growing concern due to their potential role as reservoirs and disseminators of antimicrobial resistance genes in aquatic and clinical environments. In this study, we describe the genomic characterization of a clinical <i>Aeromonas caviae</i> isolate harboring a plasmid-encoded KPC-type carbapenemase. This microorganism was isolated from a stool sample from a patient with acute gastroenteritis in May 2025. Whole-genome sequencing followed by bioinformatic analysis using ResFinder, PlasmidFinder, and MobileElementFinder revealed the presence of the <i>bla</i>_KPC-2 gene located on an IncP-6 plasmid. The plasmid carried multiple insertion sequences and composite transposons, including IS26, ISKpn3, and IS6100, suggesting a highly mobile genetic platform. Comparative analysis indicates that the plasmid structure resembles previously reported KPC-harboring plasmids found in Enterobacterales, highlighting potential interspecies transfer events. To our knowledge, this is one of the few reports describing an IncP-6 plasmid carrying <i>bla</i>_KPC-2 in <i>Aeromonas caviae</i>. These findings underscore the importance of environmental and clinical surveillance of carbapenemase-producing bacteria.</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"143-147"},"PeriodicalIF":2.2,"publicationDate":"2026-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13071764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146204481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the microbiological diagnostic algorithm for <i>Clostridioides difficile</i> infection and associated clinical factors in a tertiary care hospital.","authors":"María José Muñoz-Dávila, Genoveva Yague-Guirao, Alicia Hernández, Elisa García-Vázquez","doi":"10.37201/req/116.2025","DOIUrl":"10.37201/req/116.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"83-85"},"PeriodicalIF":2.2,"publicationDate":"2026-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935088/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146151659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Candida kefyr/Kluyveromyces marxianus</i> infection of aortic endograft.","authors":"Lucía Gómez-Barral, Blanca Burgoa-Rubido, Sergio Valverde-García, Juan Luis Muñoz-Bellido","doi":"10.37201/req/118.2025","DOIUrl":"10.37201/req/118.2025","url":null,"abstract":"","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"86-88"},"PeriodicalIF":2.2,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935082/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive performance of weekly rectal surveillance cultures and extra-rectal colonization for carbapenem-resistant Enterobacterales infections in a resource-limited ICU with KPC and NDM co-circulation.","authors":"Patricio Favier, Pedro Suárez-Urquiza, Carla Raffo, Diego Torres, Liliana Kumar, Johanna Pérez, Ivana Primost, María Inés Gallino, Fidel Pinilla-Huayta, Claudia Muñoz-Soto, Matías Ravelli, Enrique Serio, Javier Pemán-García, Amparo Valentín-Martín, Eva María González-Barberá","doi":"10.37201/req/113.2025","DOIUrl":"10.37201/req/113.2025","url":null,"abstract":"<p><strong>Background: </strong>Carbapenem-resistant Enterobacterales (CRE) cause hard-to-treat infections. Rectal surveillance is widely used to detect carriers, but its predictive value where different carbapenemases co-circulate is unclear. We assessed whether CRE rectal and extra-rectal colonization predicts subsequent infection in an intensive care unit with concurrent KPC and NDM circulation.</p><p><strong>Methods: </strong>We performed a retrospective observational study in a 60-bed adult intensive care unit in Buenos Aires, Argentina, from July 2016 to September 2019. All patients underwent weekly rectal surveillance, and extra rectal samples were taken when clinically indicated. Following up lasted 90 days from the first positive culture or from admission for non-carriers. Outcomes were any CRE infection and bacteremia. We estimated predictive values and fitted multivariable logistic regression models.</p><p><strong>Results: </strong>We included 495 patients, median age 66 years, 58% male. Of them, 66% had rectal colonization and 8% had extra-rectal colonization. CRE rectal carriage showed low PPV for any infection, about 10%, with high NPV near 94%, and it was not independently associated with infection (aOR 1.9 [0.9-4.4], p=0.1). CRE extra-rectal colonization was an independent predictor of any CRE infection (aOR 3.4 [1.4-7.9] p<0.01) and bacteremia (aOR 3.3 [1.3-8.9] p<0.05), with specificity >93% but sensitivity ≈ 20%.</p><p><strong>Conclusions: </strong>In this mixed KPC and NDM CRE setting, weekly rectal surveillance was not a predictor of later infection, while extra rectal colonization retained independent predictive value for overall infection and for bacteremia.</p>","PeriodicalId":94198,"journal":{"name":"Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia","volume":" ","pages":"49-60"},"PeriodicalIF":2.2,"publicationDate":"2026-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12935085/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}