[Impact of a dedicated multidisciplinary committee (endocarditis team) on the management and outcome of infective endocarditis in a reference center].

Javier Iglesias-Varea, Mario Fernández-Ruiz, Laura Domínguez, Jorge Boán, Eduardo Aparicio-Minguijón, Antonio Terrón, María Asunción Pérez-Jacoiste Asín, José María Aguado, Francisco López-Medrano
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Abstract

Introduction: Infective endocarditis (IE) is a complex condition associated with high morbidity and mortality. The creation of multidisciplinary teams (endocarditis team) has been shown to improve its management and prognosis. We analysed the impact of the formal implementation of a multidisciplinary IE committee (coIE) in a tertiary care hospital.

Methods: Single-centre quasi-experimental study comparing two periods: before (2010-2015) and after (2017-2021) the implementation of the coIE. The coIE met weekly (and on demand when necessary) to make decisions regarding medical and surgical management in patients with definite or possible IE, following a protocol based on international guidelines.

Results: We included 92 and 97 patients in the pre- and post-intervention periods, respectively. Demographic characteristics, predisposing factors, and types of IE were similar. No significant differences were observed in the proportion of patients with surgical indication who underwent surgery (30.2 % vs 39.1 %, respectively; p = 0.317), in-hospital mortality (27.2 % vs 34.0 %; p = 0.308), or one-year mortality (32.6 % vs 45.4 %; p = 0.073). The median (interquartile range) time from diagnosis to surgery decreased in the post-intervention period (11.5 [6.3-25.3] vs 7 [3-10] days; p = 0.026). The diagnosis of embolic events was more frequent in this period (46.7 % vs 58.8 %; p = 0.098).

Conclusion: Although we did not observe a significant impact on mortality among patients with definite IE after the implementation of an endocarditis team, we noted a favourable trend in intermediate indicators of healthcare quality.

[一个专门的多学科委员会(心内膜炎小组)对参考中心感染性心内膜炎的管理和结果的影响]。
感染性心内膜炎(IE)是一种复杂的疾病,具有很高的发病率和死亡率。建立多学科团队(心内膜炎团队)已被证明可以改善其管理和预后。我们分析了在一家三级医院正式实施多学科IE委员会(coIE)的影响。方法:采用单中心准实验研究,比较coIE实施前(2010-2015年)和实施后(2017-2021年)两个时期。coIE每周召开一次会议(必要时根据需要),根据基于国际指南的协议,就明确或可能患有IE的患者的医疗和手术治疗做出决定。结果:我们在干预前和干预后分别纳入了92例和97例患者。人口学特征、诱发因素和IE类型相似。有手术指征的患者接受手术的比例无显著差异(分别为30.2%和39.1%;P = 0.317),住院死亡率(27.2% vs 34.0%;P = 0.308)或一年死亡率(32.6% vs 45.4%;P = 0.073)。干预后,从诊断到手术的中位时间(四分位数范围)缩短了(11.5[6.3-25.3]天和7[3-10]天;P = 0.026)。栓塞事件的诊断在这一时期更为频繁(46.7% vs 58.8%;P = 0.098)。结论:虽然我们没有观察到在心内膜炎团队实施后明确IE患者的死亡率有显著影响,但我们注意到医疗质量的中间指标有良好的趋势。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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