[Impact of increasing the frequency of meetings in which the Antimicrobial Stewardship Programme team conducted prospective audit and feedback on antimicrobial consumption].

María Inmaculada Zas-García, José Manuel Fernández-Carreira, Jorge Rodríguez-Prida, Ana Blanco-Suárez, Marcos Álvarez-Pérez, Jesús Rubio-Sanz, Elsa Castelo-Alvárez, Daniel González-Fernández, Tania Rubio-Alfonso
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Abstract

Introduction: To evaluate how antimicrobial consumption was influenced by increasing the frequency of meetings in which the Antimicrobial Stewardship Program (ASP) team conducted prospective audit and feedback (PAF).

Materials and methods: Retrospective cohort study comparing consumption in DDD per 1000 beds-day and DDD per 1000 admissions across groups of anti-infectives, antibacterial groups, agents against methicillin-susceptible Staphylococcus aureus (anti-MSSA agents)/agents against methicillin-resistant Staphylococcus aureus (anti-MRSA agents), antibiotics targeting sensitive Gram-negative bacteria/antibiotics targeting resistant Gram-negative bacteria and antimicrobial agents, during two comparative periods of ASP activity (2 weekly meetings in 2023 versus 1 weekly meeting in 2022).

Results: Comparing 2023 to 2022: antibacterials for systemic use consumption increased in DDD per 1000 beds-day (+0.13%) and decreased in DDD per 1000 admissions (-3.55 %); consumption in DDD per 1000 beds-day and DDD per 1000 admissions increased for penicillins, glycopeptides and aminoglycosides while it decreased for cephalosporins and carbapenems, quinolones use increased per beds-days but decreased per admissions; regarding anti-MSSA and anti-MRSA agents, consumption of cefazolin, cloxacillin, vancomycin and daptomycin increased in DDD per 1000 beds-day and DDD per 1000 admissions, linezolid consumption increased per beds-day but decreased per admissions; for antibiotics targeting sensitive Gram-negative bacteria and antibiotics targeting resistant Gram-negative bacteria, consumption of amoxicillin-clavulanate, piperacillin-tazobactam, aminoglycosides, ceftazidime, cefepime and polymyxins increased per DDD/1000 bed-days and DDD per 1000 admissions, carbapenems consumption decreased per bed-days and admissions.

Conclusion: The increase in the frequency of meetings seems to be related to better use of antimicrobials in our center.

[增加抗菌素管理规划团队对抗菌素消耗进行前瞻性审核和反馈的会议频率的影响]。
前言:评估抗菌素管理计划(ASP)团队进行前瞻性审核和反馈(PAF)的会议频率增加对抗菌素消费的影响。材料和方法:回顾性队列研究比较抗感染组、抗菌组、甲氧西林敏感金黄色葡萄球菌药物(抗mssa药物)/耐甲氧西林金黄色葡萄球菌药物(抗mrsa药物)、针对敏感革兰氏阴性菌的抗生素/针对耐药革兰氏阴性菌的抗生素和抗菌药物的每1000张床位日用药频度和每1000例入院患者用药频度的消费量。在ASP活动的两个比较时期(2023年每周2次会议与2022年每周1次会议)。结果:2023年与2022年相比,系统使用抗菌药物每1000张床位日DDD增加(+0.13%),每1000次住院患者DDD下降(- 3.55%);青霉素类、糖肽类和氨基糖苷类药物每1000张病床日的DDD消费量和每1000次住院患者的DDD消费量增加,而头孢菌素和碳青霉烯类药物的DDD消费量减少,喹诺酮类药物每1000张病床日的使用量增加,但每次住院患者的DDD使用量减少;对于抗mssa和抗mrsa药物,头孢唑林、氯西林、万古霉素和达托霉素的用量在每1000张床位日DDD和每1000次入院DDD中增加,利奈唑胺的用量在每1000张床位日增加但在每1000次入院中减少;针对敏感革兰氏阴性菌的抗生素和针对耐药革兰氏阴性菌的抗生素,阿莫西林-克拉维酸酯、哌拉西林-他唑巴坦、氨基糖苷类、头孢他啶、头孢吡肟和多粘菌素的每DDD/1000住院日和DDD增加,碳青霉烯类药物的每住院日和住院人数减少。结论:会议频次的增加似乎与我中心更好地使用抗菌药物有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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