Revista espanola de medicina nuclear e imagen molecular最新文献

{"title":"Usefulness of bone gammagraphy as a reflection of the patient’s nutritional status, a case of scurvy","authors":"Julio Alberto Vázquez Gómez , Myriam Salvá Arteaga , Inés Roncero Sánchez-Cano , Ana Fernández Marín , María del Puy Garrastachu Zumarán , María Yolanda Ruiz del Prado","doi":"10.1016/j.remnie.2024.500012","DOIUrl":"10.1016/j.remnie.2024.500012","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Functional imaging in neuroendocrine tumors: assessment of molecular heterogeneity using [68Ga]Ga-DOTA-TOC and [18F]FDG PET/CT","authors":"Z. Nogareda Seoane ,&nbsp;M.C. Mallón Araújo ,&nbsp;A. Calatayud Cubes ,&nbsp;C. Barberán Corral ,&nbsp;Y. Domínguez Novoa ,&nbsp;A. Cousillas Castiñeira ,&nbsp;N. Martínez Lago ,&nbsp;J.M. de Matías Leralta ,&nbsp;V. Pubul Nuñez","doi":"10.1016/j.remnie.2024.500011","DOIUrl":"10.1016/j.remnie.2024.500011","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of the study was evaluate the diagnostic performance of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT in patients with histologically proven neuroendocrine tumors (NETs), as well as the correlation of the visualized findings with the tumor grade.</p></div><div><h3>Material and methods</h3><p>We included 50 patients with NETs who underwent both [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/TC. The pooled sensitivity of both scans was compared, as well as [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG for each tumor grade (grade 1/G1, grade 2/G2 and grade 3/G3). Also, the sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG as a function of the continuous variable Ki-67 was investigated. Finally, the number of lesions detected by both PET radiopharmaceuticals for each tumor grade was compared.</p></div><div><h3>Results</h3><p>The pooled sensitivity of both PET/CT (96%) was higher than [68Ga]Ga-DOTA-TOC (84%) and [¹⁸F]FDG (44%) separately, with statistically significant differences. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG in both G1 (p = 0.004) and G2 (p &lt; 0.001). In G3 the performance of both scans detected disease in 100% of this subgroup. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT correlated significantly with the Ki-67 proliferative index. In G2 patients the number of lesions detected with [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG.</p></div><div><h3>Conclusions</h3><p>The performance of both PET/CT, particularly in G2 and G3, demonstrates the molecular heterogeneity of metastatic NETs and contributes to the selection of a more appropriate treatment, particularly in those high-grade patients who may benefit from radionuclide therapy (PRRT).</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140771217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The added value of [18F]fluorocholine PET/TC in the assessment of secondary or tertiary hyperparathyroidism","authors":"S. Abouzian ,&nbsp;D.A. López-Mora ,&nbsp;A. Fernández-León ,&nbsp;C. Facundo ,&nbsp;P. Stefaneli ,&nbsp;A. Flotats","doi":"10.1016/j.remnie.2024.500005","DOIUrl":"10.1016/j.remnie.2024.500005","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Controversy in the initial nodal staging of rectal cancer (MRI or PET/CT?)","authors":"Elena López Llobet ,&nbsp;Mónica Coronado Poggio ,&nbsp;Carmen Lancha Hernández ,&nbsp;Carmen Martín Hervás ,&nbsp;Daniela Travaglio Morales ,&nbsp;Domenico Monachello Araujo ,&nbsp;Sonia Rodado Marina ,&nbsp;Luís Domínguez Gadea","doi":"10.1016/j.remnie.2024.500004","DOIUrl":"10.1016/j.remnie.2024.500004","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the usefulness of MRI and PET/CT in nodal staging (N) of patients with locally advanced rectal cancer (LARC).</p></div><div><h3>Material and methods</h3><p>Retrospective study of patients with LARC, who completed their initial staging with PET/CT, between January-20 and March-23. Regional nodes were assessed, and N was determined using both techniques according to TNM criteria. Concordance between MRI and PET/CT was analyzed. The accuracy of both techniques was calculated for those patients who underwent direct surgery. Non-regional pelvic lymph nodes were evaluated by both modalities.</p></div><div><h3>Results</h3><p>Among the 73 patients, 48 were ultimately diagnosed with a locally advanced stage. Of these, 39 underwent neoadjuvant treatment (chemoradiotherapy) followed by surgery, and 9 direct surgery. In 25, the PET/CT extension study revealed distant disease, leading to systemic treatment. Weak concordance was observed between MRI and PET/CT in determining N (k<!--> <!-->=<!--> <!-->0.286; p<!--> <!-->&lt;<!--> <!-->0.005). Out of 73 patients, 31(42%) exhibited concordance, and 42(58%) showed discordance. In 83% of the discordant cases, MRI overstaged compared to PET/CT, with 17 cases indicating nodal involvement (N+) by MRI and N0 by PET/CT. Diagnostic accuracy was 78% for both techniques. Sensitivity, specificity, positive predictive value, and negative predictive value were 80%, 75%, 80%, and 75% for MRI, and 60%, 100%, 100%, and 67%, for PET/CT. PET/CT identified pelvic metastatic adenopathies in 8 patients that were not visible/doubtful by MRI.</p></div><div><h3>Conclusions</h3><p>In the initial nodal staging of rectal cancer MRI overstages relative to PET/CT. Both modalities are complementary, PET/CT offers higher specificity and MRI higher sensitivity.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ossification of the falx cerebri in a patient with metastatic breast cancer","authors":"S. de la Torre Fernández,&nbsp;M.J Tello Galán,&nbsp;B. Aradas Cabado,&nbsp;A.E. Seva Delgado,&nbsp;C.M. Hernández Heredia,&nbsp;A.J. Fernández Sánchez","doi":"10.1016/j.remnie.2024.500001","DOIUrl":"10.1016/j.remnie.2024.500001","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Imaging of desmoplastic small round-cell tumor on 68Ga-FAPI PET/CT","authors":"Yuhong Liu ,&nbsp;Huipan Liu ,&nbsp;Zibei Wan ,&nbsp;Yue Chen ,&nbsp;Jianwen Zhang","doi":"10.1016/j.remnie.2024.500013","DOIUrl":"10.1016/j.remnie.2024.500013","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of salpingitis using 18F-FDG PET in a patient presenting with febrile syndrome of unknown origin","authors":"J.R. Garcia,&nbsp;A. Compte,&nbsp;L. Mont,&nbsp;S. Mourelo,&nbsp;P. Bassa,&nbsp;E. Riera","doi":"10.1016/j.remnie.2024.500010","DOIUrl":"10.1016/j.remnie.2024.500010","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intra and peritumoral PET radiomics analysis to predict the pathological response in breast cancer patients receiving neoadjuvant chemotherapy","authors":"Ayşegül Aksu ,&nbsp;Zeynep Gülsüm Güç ,&nbsp;Kadir Alper Küçüker ,&nbsp;Ahmet Alacacıoğlu ,&nbsp;Bülent Turgut","doi":"10.1016/j.remnie.2024.500002","DOIUrl":"10.1016/j.remnie.2024.500002","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of our study was to evaluate the contribution of 18Fluorine-Fluorodeoxyglucose Positron Emission Tomography (18F-FDG PET) radiomic data obtained from both the tumoral and peritumoral area in predicting pathological complete response (pCR) in patients with locally advanced breast cancer receiving neoadjuvant chemotherapy (NAC).</p></div><div><h3>Methods</h3><p>Female patients with a diagnosis of invasive ductal carcinoma who received NAC were evaluated retrospectively. The volume of interest (VOI) of the primary tumor (VOI-_T) was manually segmented, then a voxel-thick VOI was added around VOI-_T to define the peritumoral area (VOI-_PT). Morphological, intensity-based, histogram and texture parameters were obtained from VOIs. The patients were divided into two groups as pCR and non-complete pathological response (npCR). A “radiomic model” was created with only radiomic features, and a “patho-radiomic model” was created using radiomic features and immunohistochemical data.</p></div><div><h3>Results</h3><p>Of the 66 patients included in the study, 21 were in the pCR group. The only statistically significant feature from the primary tumor among patients with pCR and npCR was Morphological_Compacity-_T (AUC: 0.666). Between response groups, a significant difference was detected in 2 morphological, 1 intensity, 4 texture features from VOI-_PT; no correlation was found between Morphological_Compacity-_PT and NGTDM_contrast-_PT. The obtained radiomic model’s sensitivity and accuracy values were calculated as 61.9% and 75.8%, respectively (AUC: 0.786). When HER2 status was added, sensitivity and accuracy values of the patho-radiomic model increased to 85.7% and 81.8%, respectively (AUC: 0.903).</p></div><div><h3>Conclusions</h3><p>Evaluation of PET peritumoral radiomic features together with the primary tumor, rather than just the primary tumor, provides a better prediction of the pCR to NAC in patients with breast cancer.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"68Ga-FAPI and 18F-FDG PET images in a patient with tuberculosis mimicking malignant tumor on CT","authors":"Zhe Zheng ,&nbsp;Pengcheng Hu ,&nbsp;Yu Lin,&nbsp;Hongcheng Shi","doi":"10.1016/j.remnie.2024.01.001","DOIUrl":"10.1016/j.remnie.2024.01.001","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139379087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synchronous inflammatory pseudotumor-like follicular dendritic cell sarcoma of spleen and primary lung cancer: A diagnostic challenge in 18F-FDG PET/CT","authors":"Linlin Ma,&nbsp;Xueqi Chen,&nbsp;Jinzhi Chen,&nbsp;Meng Liu,&nbsp;Zhanli Fu","doi":"10.1016/j.remnie.2023.10.005","DOIUrl":"10.1016/j.remnie.2023.10.005","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71430682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}