S. Bondia Bescós, J.J. Martin Marcuartu, M.T. Bajén Lázaro, J. Mora Salvadó, A. Benítez Segura, M. Cortés Romera
{"title":"Intrahepatic splenosis visualized on a [m99Tc]Tc-denatured erythrocyte scintigraphy","authors":"S. Bondia Bescós, J.J. Martin Marcuartu, M.T. Bajén Lázaro, J. Mora Salvadó, A. Benítez Segura, M. Cortés Romera","doi":"10.1016/j.remnie.2023.01.006","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.01.006","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50191611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nuclear medicine contribution to precision surgery in breast cancer","authors":"Renato A. Valdés Olmos , Sergi Vidal-Sicart","doi":"10.1016/j.remnie.2023.07.001","DOIUrl":"10.1016/j.remnie.2023.07.001","url":null,"abstract":"<div><p><span>Nuclear medicine has significantly contributed to precision surgery in breast cancer in the past decades. Radioguided surgery (RGS) has enabled sentinel node<span><span> (SN) biopsy in assessing regional nodal involvement modifying the management of patients with early breast cancer. For the axilla the SN procedure has resulted in fewer complications and better </span>quality of life<span> when compared with axillary lymph node<span><span> dissection. Originally, SN biopsy principally concerned cT 1-2 tumours without evidence of axillary lymph node metastases. However, in last years SN biopsy is also being offered to patients with large or multifocal tumours, ductal carcinoma in situ<span><span><span>, ipsilateral breast cancer relapse<span>, and to patients receiving neoadjuvant systemic treatment (NST) for </span></span>breast sparing surgery<span>. Parallel to this evolution various scientific associations are trying to homogenise issues such as radiotracer<span> choice, breast injection site, preoperative imaging standardisation and SN biopsy timing in relation to NST as well as management of non-axillary SN </span></span></span>metastasis (e.g. internal mammary chain). Additionally, RGS is currently used to accomplish primary breast tumour excision either by intralesional radiocolloid injection or by </span></span>radioactive iodine seed implantation which is also employed to target metastatic axillary lymph nodes. This latter procedure contributes to manage the node-positive axilla in combination with </span></span></span></span><sup>18</sup>F-FDG PET/CT in an effort to tailor systemic and loco regional treatment.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10140657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Generalized ossificant myositis with intensive diffuse muscle uptake in whole body bone scan of a 13-year-old boy","authors":"Soheila Erfani , Mahdieh Vahedi , Hadis Mohammadzadeh , Abdolreza Malek , Atena Aghaee","doi":"10.1016/j.remnie.2023.05.002","DOIUrl":"10.1016/j.remnie.2023.05.002","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10197863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Amaya , A. Repetto , S. Rubí , J. Fuster , M. Martínez , A. García-Granero
{"title":"18F-DOPA PET/CT: Diagnosis of a synchronous appendiceal neuroendocrine tumor in a patient with Medullary Thyroid Cancer","authors":"J. Amaya , A. Repetto , S. Rubí , J. Fuster , M. Martínez , A. García-Granero","doi":"10.1016/j.remnie.2023.03.003","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.03.003","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50191577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francisco Sebastián Palacid, Noelia Álvarez Mena, Rosanna del Carmen Zambrano Infantino, María García Aragón, Mercedes Alonso Rodríguez, Berta Pérez López, Claudia Gamazo Laherrán, María Jesús González Soto, Ricardo Ruano Pérez
{"title":"Absolute quantification of myocardial uptake of 99mTc-DPD in patients with cardiac amyloidosis due to transthyretin deposits (ATTR)","authors":"Francisco Sebastián Palacid, Noelia Álvarez Mena, Rosanna del Carmen Zambrano Infantino, María García Aragón, Mercedes Alonso Rodríguez, Berta Pérez López, Claudia Gamazo Laherrán, María Jesús González Soto, Ricardo Ruano Pérez","doi":"10.1016/j.remnie.2023.04.007","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.04.007","url":null,"abstract":"<div><h3>Purpose</h3><p>To determine the diagnostic contribution of the absolute quantification of the myocardial deposit of <sup>99m</sup><span>Tc-DPD in patients<span> with cardiac amyloidosis<span> due to transthyretin deposits (ATTR).</span></span></span></p></div><div><h3>Materials and methods</h3><p><span>SPECT/CT was performed in 41 patients with positive scintigraphic results for ATTR cardiac amyloidosis. The patients were divided into two groups (Perugini grades 2 and 3) and the SUVmax at the level of the bone and both ventricles and the percentage of dose calculated in these areas were calculated. The Student's </span><em>t</em>-test was used to compare results and the area under the curve (AUC) was calculated to assess differential efficacy and establish discriminatory cut-off points between both groups of patients.</p></div><div><h3>Results</h3><p>Statistically significant differences were observed in all the study variables, with the exception of bone SUV<sub>max</sub>. The differences with the greatest statistical power were observed in the variables SUV<sub>maxRV</sub> and the percentage of dose in both ventricles (p < 0.001). The cut-off point obtained for the variable SUVm<sub>axLV</sub> was 8.620 (sensitivity 87.9% and specificity 100%; AUC 0.966), while that of the variable SUV<sub>maxRV</sub> was 6.195 (sensitivity 81.8% and specificity 100%; AUC 0.955).</p></div><div><h3>Conclusions</h3><p>The absolute quantification of myocardial uptake of <sup>99m</sup>Tc-DPD in the SPECT/CT images of patients with suspected cardiac amyloidosis due to transthyretin deposits represents a new diagnostic tool that allows adequate classification of patients according to the Perugini visual grading scale.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50191652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adolfo Gómez-Grande , Alexander P. Seiffert , Alberto Villarejo-Galende , Marta González-Sánchez , Sara Llamas-Velasco , Héctor Bueno , Enrique J. Gómez , María José Tabuenca , Patricia Sánchez-González
{"title":"Static first-minute-frame (FMF) PET imaging after 18F-labeled amyloid tracer injection is correlated to [18F]FDG PET in patients with primary progressive aphasia","authors":"Adolfo Gómez-Grande , Alexander P. Seiffert , Alberto Villarejo-Galende , Marta González-Sánchez , Sara Llamas-Velasco , Héctor Bueno , Enrique J. Gómez , María José Tabuenca , Patricia Sánchez-González","doi":"10.1016/j.remnie.2023.02.001","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.02.001","url":null,"abstract":"<div><h3>Objective</h3><p>To study the correlation between a static PET image of the first-minute-frame (FMF) acquired with <sup>18</sup>F-labeled amyloid-binding radiotracers and brain [<sup>18</sup>F]FDG PET in patients with primary progressive aphasia (PPA).</p></div><div><h3>Material and methods</h3><p>The study cohort includes 17 patients diagnosed with PPA with the following distribution: 9 nonfluent variant PPA, 4 logopenic variant PPA, 1 semantic variant PPA, 3 unclassifiable PPA. Regional SUVRs are extracted from FMFs and their corresponding [<sup>18</sup>F]FDG PET images and Pearson’s correlation coefficients are calculated.</p></div><div><h3>Results</h3><p>SUVRs of both images show similar patterns of regional cerebral alterations. Intrapatient correlation analyses result in a mean coefficient of <em>r</em> <!-->=<!--> <!-->0.94<!--> <!-->±<!--> <!-->0.06. Regional interpatient correlation coefficients of the study cohort are greater than 0.81. Radiotracer-specific and variant-specific subcohorts show no difference in the similarity between the images.</p></div><div><h3>Conclusions</h3><p>The static FMF could be a valid alternative to dynamic early-phase amyloid PET proposed in the literature, and a neurodegeneration biomarker for the diagnosis and classification of PPA in amyloid PET studies.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50199438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Jiménez-Granero , J.I. Rayo-Madrid , J.R. Infante-de-la-Torre , J. Serrano-Vicente , A. Martínez-Esteve , A. Baena-García , A. Utrera-Costero , R. Juárez-Vela
{"title":"Completion of the informed consent in radioguided surgery by the General Surgery and Nuclear Medicine services of a radioguided surgery unit","authors":"P. Jiménez-Granero , J.I. Rayo-Madrid , J.R. Infante-de-la-Torre , J. Serrano-Vicente , A. Martínez-Esteve , A. Baena-García , A. Utrera-Costero , R. Juárez-Vela","doi":"10.1016/j.remnie.2023.05.003","DOIUrl":"10.1016/j.remnie.2023.05.003","url":null,"abstract":"<div><h3>Objective</h3><p>To identify the frequency of errors in informed consent documents in radioguided surgery in a third level hospital and to detect possible causes or factors associated with a greater risk of error.</p></div><div><h3>Material and methods</h3><p>Informed consent forms of a total of 369 radioguided surgery interventions, completed by the Nuclear Medicine and General Surgery services, were analyzed, and the degree of completion of the forms and its correlation with the physicians responsible, type of pathology, intervention, and waiting time were compared with the completion of consent by another specialty.</p></div><div><h3>Results</h3><p>Errors were identified in 22 consent forms from Nuclear Medicine and 71 from General Surgery. The most common error was the absence of identification of the physician responsible (17 in Nuclear Medicine, 51 in General Surgery), and the second most common was the absence of a document (2 in Nuclear Medicine, 20 in General Surgery). There were significant differences in the errors made depending on the doctor in charge, with no significant correlation with the other variables.</p></div><div><h3>Conclusions</h3><p>The physicians responsible were the main factor associated with a greater risk of error in the completion of informed consent forms. Further studies are needed to analyze the causal factors and possible interventions to minimize errors.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10152262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}