Revista espanola de medicina nuclear e imagen molecular最新文献

{"title":"Splenic and lung metastases of hepatocellular carcinoma detected at 13N-ammonia PET/CT","authors":"Valentina Scolozzi , Romina Grazia Giancipoli , Frediano Inzani , Francesca Romana Ponziani , Silvia Taralli","doi":"10.1016/j.remnie.2023.06.006","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.06.006","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71732622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"18F-FDG imaging of disseminated non-tuberculous mycobacteria infection in a patient with AIDS","authors":"L. Li , H. Wang , F. Li, L. Xiao, Y. Li","doi":"10.1016/j.remnie.2023.07.005","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.07.005","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71732620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-vivo lymphoscintigraphy of sinonasal tumors identifies retropharyngeal node and level I as predominant sentinel nodes","authors":"S. Panda ,&nbsp;A. Nath ,&nbsp;A. Thakar ,&nbsp;R. Kumar ,&nbsp;V. Seenu ,&nbsp;K. Sikka ,&nbsp;C.A. Singh ,&nbsp;R. Kumar","doi":"10.1016/j.remnie.2023.06.007","DOIUrl":"10.1016/j.remnie.2023.06.007","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate by in- vivo lymphoscintigraphy and SPECT-CT imaging, the lymphatic drainage patterns of para-nasal sinus(PNS) tumors. To confirm or refute the belief of the retropharyngeal lymph node (RPLN) being the significant draining lymph node for such tumors.</p></div><div><h3>Methods</h3><p>Prospective cohort study conducted on previously untreated PNS tumors with no clinico-radiological evidence of lymph node metastasis. Lymphoscintigraphy undertaken by nasal endoscopic assisted peritumoral injection of ^99mTc Sulfur colloid. Injections were classified as anterior or posterior as per a vertical line along the maxillary sinus ostium.</p></div><div><h3>Results</h3><p>17 patients were included. Lymphoscintigraphy successfully identified 17 sentinel nodes in 15 patients and was unsuccessful (lymphoscintigraphy failure) in 2 patients. Predominant sites of sentinel lymphatic drainage were noted to be the RPLN (n = 8; 47%), and Level I (n = 7; 42%). Occasional drainage was identified at the peri-parotid node(n = 1) and at Level II (n = 1). Contralateral drainage was noted in 2 patients (level I-1 and RPLN-1).</p><p>Anterior injections drained predominantly to Level I (6/8) and RPLN (2/8), while posterior injections drained predominantly to the RPLN ( 6/7). The relative risk of RPLN being identified as the sentinel node was significantly higher for posteriorly placed injections than for anteriorly placed injections (RR- 3.43; 95% CI-1.0-11.8, p = 0.05).</p></div><div><h3>Conclusion</h3><p>The RPLN is noted as a frequent draining node for sino-nasal tumours and merits routine attention in all sino-nasal tumors. The radio-colloid SPECT-CT technique described here offers an excellent in-vivo technique to further explore and validate the lymphatic drainage pathways of these tumours.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10193223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"99mTc-MIP-1404 CZT SPECT/CT versus 68Ga/PSMA-11 PET/CT: Imaging of prostate cancer metastasis","authors":"A. Saudi ,&nbsp;P. Takhar ,&nbsp;F. Aljabery ,&nbsp;M. Ochoa-Figueroa","doi":"10.1016/j.remnie.2023.06.003","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.06.003","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71732621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal Castleman’s disease with 18F-FDG PET/CT","authors":"Álvaro Badenes Romero ,&nbsp;Marta Milà López ,&nbsp;Rolando Omar Vallansot ,&nbsp;Carlos Andrés Achury Murcia ,&nbsp;Maria Patricia Fierro Alanis ,&nbsp;David Carrera Salazar ,&nbsp;Vicente Izquierdo Muro ,&nbsp;Liliana María Quintero Caicedo","doi":"10.1016/j.remnie.2023.06.008","DOIUrl":"10.1016/j.remnie.2023.06.008","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9771204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic value of primary tumor and lymph node volumetric metabolic parameters at pre-treatment F-18 FDG PET/CT in nasopharyngeal carcinoma","authors":"Bedriye Büşra Demirel ,&nbsp;Seda Gülbahar Ateş ,&nbsp;Ebru Atasever Akkaş ,&nbsp;Fatih Göksel ,&nbsp;Gülin Uçmak","doi":"10.1016/j.remnie.2023.06.004","DOIUrl":"10.1016/j.remnie.2023.06.004","url":null,"abstract":"<div><h3>Background</h3><p>The aim of this study was to evaluate the prognostic significance of volumetric metabolic parameters of pre-treatment PET/CT along with clinical characteristics in patients<span> with non-metastatic nasopharyngeal carcinoma.</span></p></div><div><h3>Material and methods</h3><p><span><span>Seventy-nine patients with nasopharyngeal carcinoma underwent F18- FDG PET/CT for pretreatment evaluation and included in this study. The patient features (patient age, tumor histopathology, T and N stage, size of primary tumor and the largest cervical lymph node) and PET parameters were analyzed: maximum, mean and peak </span>standardized uptake values (SUVmax, SUVmean, SUVpeak), metabolic tumor volume (MTV), and total lesion glycolysis (TLG) for primary tumor and largest </span>cervical lymph node<span>. After treatment<span>, patients were evaluated for disease progression and mortality. Survival analysis for progression-free survival (PFS) and over-all survival (OS) was performed with Kaplan–Meier method using PET findings and clinical characteristics.</span></span></p></div><div><h3>Results</h3><p>The median follow-up duration was 29.7 months (range 3–125 months). Among clinical characteristics, no parameters had significance association for PFS. Primary tumor-MTV and cervical lymph node-MTV were independent prognostic factors for PFS (p = 0.025 and p = 0.004, respectively).Patients with primary tumor-MTV &gt;19.4 and patients with lymph node-MTV&gt;3.4 had shorter PFS. For OS, age and the size of the lymph node were independent prognostic factor (p = 0.031 and p = 0.029).Patients with age over 54 years and patients with lymph node size &gt;1 cm were associated with decreased OS.</p></div><div><h3>Conclusion</h3><p>Primary tumor-MTV and lymph node-MTV on pre-treatment PET/CT are significant prognostic factors for long-term PFS in non-metastatic nasopharyngeal carcinoma.</p><p>We consider that measuring MTV as volume-based metabolic parameter on pretreatment PET/CT may contribute decision of treatment intensity and individualized risk stratification and may improve long-term PFS. Additionally, age and the size of lymph node are independent prognostic factors for mortality.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9751403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolic characterization of structural lung changes in patients with findings suggestive of incidental COVID-19 pneumonia on 18F-FDG PET/CT. Pathophysiological insights from multimodal images obtained during the pandemic","authors":"C.G. Wakfie-Corieh ,&nbsp;F. Ferrando-Castagnetto ,&nbsp;M. García-Esquinas ,&nbsp;M.N. Cabrera-Martín ,&nbsp;C. Rodríguez Rey ,&nbsp;A. Ortega Candil ,&nbsp;R.M. Couto Caro ,&nbsp;J.L. Carreras Delgado","doi":"10.1016/j.remnie.2023.07.004","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.07.004","url":null,"abstract":"<div><h3>Purpose</h3><p><span>To evaluate the metabolic uptake of different tomographic signs observed in patients with incidental structural findings suggestive of COVID-19 pneumonia through </span>¹⁸F-FDG PET/CT.</p></div><div><h3>Materials and Methods</h3><p>: We retrospectively analyzed 596 PET/CT studies performed from February 21, 2020 to April 17, 2020. After excluding 37 scans (non-¹⁸<span>F-FDG PET tracers and brain studies), we analyzed the metabolic activity of several structural changes integrated in the CO-RADS score using the SUVmax of multimodal studies with </span>¹⁸F-FDG.</p></div><div><h3>Results</h3><p>Forty-three patients with ¹⁸F-FDG PET/CT findings suggestive of COVID-19 pneumonia were included (mean age: 68<!--> <!-->±<!--> <!-->12.3 years, 22 male). SUVmax values were higher in patients with CO-RADS categories 5−6 than in those with lower CO-RADS categories (6.1<!--> <!-->±<!--> <!-->3.0 vs. 3.6<!--> <!-->±<!--> <!-->2.1, p<!--> <!-->=<!--> <span>0.004). In patients with CO-RADS 5−6, ground-glass opacities, bilaterality and consolidations exhibited higher SUVmax values (p-values of 0.01, 0.02 and 0.01, respectively). Patchy distribution and crazy paving pattern were also associated with higher SUVmax (p-values of 0.002 and 0.01). After multivariate analysis, SUVmax was significantly associated with a positive structural diagnosis of COVID-19 pneumonia (odds ratio</span> <!-->=<!--> <!-->0.63, 95% confidence interval<!--> <!-->=<!--> <!-->0.41−0.90; p<!--> <!-->=<!--> <!-->0.02). The ROC curve of the regression model intended to confirm or rule out the structural diagnosis of COVID-19 pneumonia showed an AUC of 0.77 (standard error<!--> <!-->=<!--> <!-->0.072, p<!--> <!-->=<!--> <!-->0.003).</p></div><div><h3>Conclusions</h3><p>In those patients referred for standard oncologic and non-oncologic indications (43/559; 7.7%) during pandemic, imaging with ¹⁸F-FDG PET/CT is a useful tool during incidental detection of COVID-19 pneumonia. Several CT findings characteristic of COVID-19 pneumonia, specifically those included in diagnostic CO-RADS scores (5−6), were associated with higher SUVmax values.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71732624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radioguided surgery of mesenchymal tumors with 125I seeds","authors":"Alberto G. Barranquero ,&nbsp;Sara Corral Moreno ,&nbsp;Alberto Martínez Lorca ,&nbsp;Lourdes Hernández-Cosido ,&nbsp;María Eugenia Rioja Martín ,&nbsp;Antonio Mena Mateo ,&nbsp;Jacobo Cabañas Montero ,&nbsp;Jose María Fernández-Cebrián","doi":"10.1016/j.remnie.2023.04.004","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.04.004","url":null,"abstract":"<div><h3>Introduction</h3><p><span>Radioguided surgery uses radioactive substances to identify and remove hard-to-locate lesions. Mesenchymal tumors constitute a heterogeneous group of neoplasms derived from the mesoderm<span>, including benign lesions and malignant sarcomas. The aim of this study was to evaluate the ability of </span></span>¹²⁵I radioactive seeds to guide intraoperative localization of mesenchymal tumors, analyzing the complication rates and evaluating the margins of the surgical specimens retrieved.</p></div><div><h3>Methods</h3><p>Retrospective observational study of all consecutive patients undergoing radioguided surgery of a mesenchymal tumor with a ¹²⁵<span>I radioactive seed from January 2012 to January 2020 at a tertiary referral center in Spain. The seed was inserted percutaneously guided by ultrasound or computed tomography in an outpatient setting.</span></p></div><div><h3>Results</h3><p>Fifteen lesions were resected in 11 interventions in 11 patients, recovering all lesions marked (100%) with a ¹²⁵<span><span>I seed. The lesions included areas of benign fibrosis (26.7%), cellular angiofibroma<span> (6.7%), desmoid tumor (20%), </span></span>solitary fibrous tumor<span> (13.3%), chondrosarcoma<span> (6.7%), and pleomorphic sarcoma (26.7%), with a high rate of recurrent tumors (60%). There was only one complication (6.7%) due to the seed falling within the surgical bed. According to the UICC classification of residual tumors, 80% of the lesions resulted in an R0 resection, 6.7% were R1 resections, and 13.3% were R2 resections.</span></span></span></p></div><div><h3>Conclusion</h3><p>Radioguided surgery is an accurate technique for the resection of hard-to-locate mesenchymal tumors.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50191651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance of different cardiac stress protocols for myocardial perfusion imaging for the diagnosis of coronary artery disease using a cadmium-zinc-telluride camera with invasive coronary angiography correlation","authors":"Miguel Ochoa-Figueroa ,&nbsp;Jeronimo Frias-Rose ,&nbsp;Elin Good ,&nbsp;Veronica Sanchez-Rodriguez ,&nbsp;Anette Davidsson ,&nbsp;Christos Pagonis","doi":"10.1016/j.remnie.2022.09.001","DOIUrl":"10.1016/j.remnie.2022.09.001","url":null,"abstract":"<div><h3>Purpose</h3><p><span><span>To evaluate the diagnostic performance of three different cardiac stress protocols for </span>myocardial perfusion imaging (MPI) using a cadmium-zinc-telluride (CZT) camera with invasive coronary </span>angiography<span> (ICA) correlation for the diagnosis of coronary artery disease in a high risk population.</span></p></div><div><h3>Methods</h3><p><span>Retrospective study of 263 patients (96 women and 167 males, mean age 68 years) from which 119 patients performed a bicycle stress test (BST), 113 pharmacological stress test (PST) and 31 a combination of the two (CST) between September 2014 and December 2018. The patients then underwent myocardial perfusion imaging (MPI), followed by ICA and evaluated by means of quantitative angiography software, within six months after the MPI. The mean pre-test probability score for coronary disease according to the European Society of </span>Cardiology criteria was 36% for the whole population. The MPI was performed in a dedicated CZT cardio camera (D-SPECT Spectrum Dynamics) with a two-day protocol, according to the European Association of Nuclear Medicine guidelines.</p></div><div><h3>Results</h3><p>No significant difference was observed between the three stress protocols in terms of diagnostic accuracy (BST 85%, PST 88%, CST 84%). The overall diagnostic accuracy of MPI to identify patients with any obstructive CAD at ICA was 86%, Sensitivity 93%, Specificity 54%, PPV 90% and NPV 63%.</p></div><div><h3>Conclusion</h3><p>The CZT D-SPECT camera achieves overall satisfactory results in the diagnosis of CAD, observing no significant differences in the diagnostic performance when the stress test was performed as a BST, PST or CST.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10514141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between immunohistochemical parameters, bone marrow fibrosis and bone marrow 18F-FDG uptake in multiple myeloma patients undergoing PET/CT examination","authors":"Ali Ozan Oner ,&nbsp;Çiğdem Özdemir ,&nbsp;Filiz Yavaşoğlu ,&nbsp;Yiğit Şenol ,&nbsp;Sena Naz Adsız","doi":"10.1016/j.remnie.2023.03.002","DOIUrl":"https://doi.org/10.1016/j.remnie.2023.03.002","url":null,"abstract":"<div><h3>Purpose</h3><p>The aim of this study was to determine the power of the SUVmax value obtained from ¹⁸<span>F-FDG PET/CT in multiple myeloma<span><span> (MM) patients to be able to predict immunophenotype characteristics (CD20, CD44, CD56, CD117, CD138 antigen expressions), bone marrow fibrosis, </span>cyclin D1 oncogene, and M-protein subtypes which play a role in diagnosis-treatment and prognosis of the disease.</span></span></p></div><div><h3>Material and method</h3><p><span><span>The study included 54 patients with multiple myeloma who underwent PET/CT for initial staging and bone marrow biopsy. The relationship was examined in these patients between the SUVmax value measured from the </span>iliac bone region and the immunohistochemical and bone marrow fibrosis data of the biopsy taken from the iliac bone. The Mann Whitney </span><em>U</em> test was used in the comparisons of dependent paired groups, and the Kruskal Wallis H test in the comparisons of three or more groups.</p></div><div><h3>Results</h3><p><span>The median SUVmax value was 4.5 (1.9−15.6) in patients<span> with CD117 antigen positivity, which was statistically significantly higher than the value in the patients with CD117 negativity (</span></span><em>p</em><span> = 0.031). When patient grouping was made according to the reticulin level; we found that the median SUVmax value was 4.9 (3.0−14.8) in the group with increased fibrosis and 3.6 (1.6−15.6) in the group with low fibrosis. The median SUVmax was statistically significantly higher in the group with increased fibrosis compared to the group with low fibrosis (</span><em>p</em><span><span> = 0.004). No statistically significant difference was determined in the comparisons of the SUVmax values when the patients were grouped according to the immunoglobulin heavy chain and light chain, </span>CD20, CD44, CD56, and cyclin D1 characteristics (</span><em>p</em> &gt; 0.05).</p></div><div><h3>Conclusion</h3><p>In MM patients who underwent PET/CT for initial staging, significant relationships were determined between FDG uptake in the bone marrow (SUVmax) and CD117 antigen and bone marrow fibrosis, which is an important prognostic factor. Higher SUVmax values were determined in the bone marrow of patients with increased fibrosis and CD117 positivity.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50191576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}