Lira Pelari-Mici, Raquel Jover Díaz, Eduardo Albers Acosta, Cristina Quicios Dorado, Isabel López Villar, Daniella Tamayo Carabaño, Luis Alberto San José Manso
{"title":"Bilateral testicular uptake in <sup>18</sup>F-DCFPyL PET-CT in prostate cancer patients: report of two cases.","authors":"Lira Pelari-Mici, Raquel Jover Díaz, Eduardo Albers Acosta, Cristina Quicios Dorado, Isabel López Villar, Daniella Tamayo Carabaño, Luis Alberto San José Manso","doi":"10.1016/j.remnie.2026.500300","DOIUrl":"10.1016/j.remnie.2026.500300","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500300"},"PeriodicalIF":0.0,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146260562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S G Dos Santos, A M Fernandes, G Ferreira, A P Santos, I L Sampaio
{"title":"Treatment of lung neuroendocrine tumors with <sup>177</sup>Lu-DOTATATE: Experience from a Tertiary Oncology Center.","authors":"S G Dos Santos, A M Fernandes, G Ferreira, A P Santos, I L Sampaio","doi":"10.1016/j.remnie.2026.500281","DOIUrl":"10.1016/j.remnie.2026.500281","url":null,"abstract":"<p><strong>Purpose: </strong>Evidence from randomized control trials supporting peptide receptor radionuclide therapy (PRRT) with [177Lu]Lu DOTATATE in patients with lung neuroendocrine tumors (NETs) is limited. Real world data is needed.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study of patients with metastatic or unresectable lung carcinoid tumors treated with [177Lu]Lu-DOTATATE at a single Tertiary Oncology Center. Radiographic response (objective response rate - ORR; disease control rate - DCR), progression-free survival (PFS), overall survival (OS) and treatment toxicity (CTCAE v4) were assessed. Exploratory univariate Cox regression analyses were performed to evaluate predictors of PFS and OS.</p><p><strong>Results: </strong>Twenty-two patients were included. The ORR was 31.8%, with DCR of 63.6%. Median PFS was 19 months (95% CI, 10-28), and median OS was 46 months (95% CI, 38-53). No grade 3/4 toxicities were observed. Symptom improvement was reported in 35.7% of symptomatic patients. Prior treatment with somatostatin analogues was significantly associated with longer PFS (HR 0.18, 95% CI, 0.05-0.62, p = 0.007), while respiratory symptoms were associated with shorter PFS (HR 5.01, 95% CI, 1.44-17.87, p = 0.012).</p><p><strong>Conclusions: </strong>PRRT with [177Lu]Lu-DOTATATE appears to be safe and effective for patients with advanced lung carcinoids. These findings support PRRT as a valuable treatment option in selected patients, while highlighting the urgent need for prospective trials to establish its role in lung NETs.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500281"},"PeriodicalIF":0.0,"publicationDate":"2026-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146260608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J R Garcia, M Camen Mir, A Compte, L Mont, L Pinilla, S Ruiz, M Soria, E Riera
{"title":"Characterization of indeterminate renal masses using immunoPET with 89Zr-Girentuximab: presentation of two clinical cases.","authors":"J R Garcia, M Camen Mir, A Compte, L Mont, L Pinilla, S Ruiz, M Soria, E Riera","doi":"10.1016/j.remnie.2026.500284","DOIUrl":"10.1016/j.remnie.2026.500284","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500284"},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146138176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J R Garcia, L L Mont, A Compte, L Pinilla, E Valls, E Riera
{"title":"Early diagnosis of synchronous bilateral breast cancer using bilateral breast-selective prone-position [18F]FDG PET/MRI.","authors":"J R Garcia, L L Mont, A Compte, L Pinilla, E Valls, E Riera","doi":"10.1016/j.remnie.2026.500282","DOIUrl":"10.1016/j.remnie.2026.500282","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500282"},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146138219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A K Minguillán Van Kapel, S De la Torre Fernández, D Castro Cardenas, M J Tello Galán, B Aradas Cabado, C M Hernández Heredia
{"title":"Disseminated melioidosis in a patient with fever of unknown origin: utility of <sup>18</sup>F-FDG-PET/CT and ROLL in clinical management and follow-up.","authors":"A K Minguillán Van Kapel, S De la Torre Fernández, D Castro Cardenas, M J Tello Galán, B Aradas Cabado, C M Hernández Heredia","doi":"10.1016/j.remnie.2026.500286","DOIUrl":"10.1016/j.remnie.2026.500286","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500286"},"PeriodicalIF":0.0,"publicationDate":"2026-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146138168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Villena-Salinas, M I Morales-Lozano, G A Jiménez Londoño, F Pérez-Ángel, M Gallego-Peinado
{"title":"Characterization by <sup>18</sup>F-FDG PET-CT and MRI of a rare benign abdominal lesion: Enlarged cisterna chyli.","authors":"J Villena-Salinas, M I Morales-Lozano, G A Jiménez Londoño, F Pérez-Ángel, M Gallego-Peinado","doi":"10.1016/j.remnie.2026.500280","DOIUrl":"10.1016/j.remnie.2026.500280","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500280"},"PeriodicalIF":0.0,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146133957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pretreatment 18F-FDG PET/CT in predicting the survival of patients with hepatic neuroendocrine tumors","authors":"Y. Zhang , G. Liu , L. Zhong , B. Li , Y. Zhang","doi":"10.1016/j.remnie.2025.500198","DOIUrl":"10.1016/j.remnie.2025.500198","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the prognostic value of pretreatment 2-[<sup>18</sup>F]-fluoro-2-deoxy-<span>d</span>-glucose (<sup>18</sup><span>F-FDG) positron emission tomography/computed tomography (PET/CT) in patients with hepatic neuroendocrine tumors (HNET).</span></div></div><div><h3>Methods</h3><div><span>In total, 41 patients were included in this study. PET-derived metabolic parameters, including maximum and mean standardized uptake values (SUV</span><sub>max</sub> and SUV<sub>mean</sub><span>, respectively), metabolic tumor volume (MTV), and total lesion glycolysis (TLG), of the tumors were measured. Meanwhile, clinical data, including tumor pathological findings such as the Ki-67 index were also assessed. Progression-free survival (PFS) and overall survival (OS) were evaluated. Univariate and multivariate analyses were performed to predict the prognostic value of clinical variables and PET-derived metabolic parameters in HNET patients. Correlation between PET-derived metabolic parameters and Ki-67 was estimated.</span></div></div><div><h3>Results</h3><div><span>Univariate analyses revealed that among PET-derived metabolic parameters, SUV</span><sub>max</sub>, SUV<sub>mean</sub><span>, and TLG were significant prognostic factors for OS (</span><em>P</em> < .05). Among clinical variables, the Ki-67 index and radical surgical resection were significant factors for both PFS and OS (<em>P</em> < .05). In multivariate analyses, only Ki-67 index was an independent prognostic factor for both PFS and OS (<em>P</em> < .05). Ki-67 index presented correlates with SUV<sub>max</sub> and SUV<sub>mean</sub> (R = 0.566, <em>P</em> < .001, R = 0.493, <em>P</em> = .001, respectively).</div></div><div><h3>Conclusions</h3><div>In patients with HNET, the Ki-67 index was an independent prognostic factor for both PFS and OS, while SUV<sub>max</sub>, SUV<sub>mean</sub>, and TLG measured on pretreatment <sup>18</sup>F-FDG PET/CT scans were prognostic factors for predicting OS. Ki-67 index also presented correlates with SUV<sub>max</sub> and SUV<sub>mean</sub>. <sup>18</sup>F-FDG-PET may be useful as quantitative predicting prognostic imaging biomarkers, especially in poorly differentiated HNET.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 1","pages":"Article 500198"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Massive subcutaneous emphysema and complete resorption images detected on [18F]-FDG PET/CT","authors":"M.T. Tatoğlu , H. Uslu","doi":"10.1016/j.remnie.2025.500180","DOIUrl":"10.1016/j.remnie.2025.500180","url":null,"abstract":"<div><div>Subcutaneous emphysema<span> may occur iatrogenically, spontaneously, or post-traumatically as a result of free air passage under the skin from the respiratory tract or gastrointestinal tract. In this case, we present the typical appearance of a case of massive subcutaneous emphysema observed on [18F]-FDG PET/CT for metabolic characterization due to a massive lesion in the lung and the images of complete resorption after seven months.</span></div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 1","pages":"Article 500180"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144370014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F. Sebastián Palacid, B. Pérez López, N. Álvarez Mena, C. Riola Parada, C. Gamazo Laherrán, R. Ruano Pérez
{"title":"Metabolic alterations on brain [18F]FDG PET in a case of postcoital transient global amnesia","authors":"F. Sebastián Palacid, B. Pérez López, N. Álvarez Mena, C. Riola Parada, C. Gamazo Laherrán, R. Ruano Pérez","doi":"10.1016/j.remnie.2025.500203","DOIUrl":"10.1016/j.remnie.2025.500203","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"45 1","pages":"Article 500203"},"PeriodicalIF":0.0,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145008609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}