M. Mangas Losada, I. García Megías, X. Boulvard Chollet, L. Romero Robles, P. Garrastachu Zumarán, R. Ramírez Lasanta
{"title":"Incidental detection by 18F-FDG PET/CT of a thyroid metastasis caused by rectal adenocarcinoma","authors":"M. Mangas Losada, I. García Megías, X. Boulvard Chollet, L. Romero Robles, P. Garrastachu Zumarán, R. Ramírez Lasanta","doi":"10.1016/j.remnie.2024.02.003","DOIUrl":"10.1016/j.remnie.2024.02.003","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 115-116"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.P. Caresia , J. Jo Rosales , M. Rodríguez Fraile , A. Arçay Öztürk , C. Artigas , On behalf of the Oncology Task Force of Spanish Nuclear Medicine and Molecular Imaging Society
{"title":"PET/CT FAPI: Procedure and evidence review in oncology","authors":"A.P. Caresia , J. Jo Rosales , M. Rodríguez Fraile , A. Arçay Öztürk , C. Artigas , On behalf of the Oncology Task Force of Spanish Nuclear Medicine and Molecular Imaging Society","doi":"10.1016/j.remnie.2024.02.005","DOIUrl":"10.1016/j.remnie.2024.02.005","url":null,"abstract":"<div><p>Neoplasms are composed of malignant tumor cells, which are surrounded by other non-tumor cellular elements, in what has been defined as the microenvironment or tumor stroma. Evidence on the importance of the tumor microenvironment has not stopped growing in recent years. It plays a central role in cell proliferation, tissue invasion, angiogenesis and cell migration.</p><p>The paradigm is the family of new FAPI radiopharmaceuticals that show the density of the fibroblast activation protein (FAP) which is overexpressed in the cell membrane of activated cancer-associated fibroblasts (CAF), and its presence is related to poor prognosis.</p><p>This educational document includes the procedure for performing PET/CT FAPI, biodistribution and the main potentially clinical applications in oncology to date.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 130-140"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Bondia-Bescós , I.E. Sanchez-Rodríguez , V. Carrero-Vasquez , A. Palomar-Muñoz , M. Maristany-Bosch , M. Cortés-Romera
{"title":"Role of [18F]F-FDG PET/CT in the detection and differential diagnosis of peritoneal tuberculosis","authors":"S. Bondia-Bescós , I.E. Sanchez-Rodríguez , V. Carrero-Vasquez , A. Palomar-Muñoz , M. Maristany-Bosch , M. Cortés-Romera","doi":"10.1016/j.remnie.2024.02.004","DOIUrl":"10.1016/j.remnie.2024.02.004","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 128-129"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of three-phase bone scintigraphy in malignancy assessment in extraosseous lesions: Two different bone scan patterns","authors":"P. Zaragoza-Ballester, M.J. Tabuenca","doi":"10.1016/j.remnie.2023.12.001","DOIUrl":"10.1016/j.remnie.2023.12.001","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 121-123"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Á. Esteban Hurtado , J. Orozco Cortés , P. Cárcamo Ibarra , U. López González , Á. Badenes Romero , M.Á. Navas de la Cruz , C. Siscar Gelo , L. Casas Calabuig , P. Abreu Sánchez , T. Mut Dólera , D. Balaguer Muñoz , M.D. Reyes Ojeda , C. Plancha Mansanet , E. Caballero Calabuig
{"title":"Concordance between freehand SPECT and conventional scintigraphy for sentinel lymph node detection in breast cancer","authors":"Á. Esteban Hurtado , J. Orozco Cortés , P. Cárcamo Ibarra , U. López González , Á. Badenes Romero , M.Á. Navas de la Cruz , C. Siscar Gelo , L. Casas Calabuig , P. Abreu Sánchez , T. Mut Dólera , D. Balaguer Muñoz , M.D. Reyes Ojeda , C. Plancha Mansanet , E. Caballero Calabuig","doi":"10.1016/j.remnie.2024.02.007","DOIUrl":"10.1016/j.remnie.2024.02.007","url":null,"abstract":"<div><h3>Introduction</h3><p>Freehand SPECT can be a useful imaging technique for preoperative planning of sentinel lymph node biopsy (SLNB) as it allows localization of the sentinel node by 3D and real-time tomographic imaging and determines its depth after a few minutes of scanning.</p><p>The aim of the study was to evaluate the correlation between the number of detected SNs between freehand SPECT images and lymphoscintigraphy (LS).</p></div><div><h3>Materials and methods</h3><p>100 patients with a diagnosis of invasive breast cancer and no clinical evidence of lymph node involvement prospectively underwent SLNB. The preoperative study included freehand SPECT imaging at 15<!--> <!-->min after injection and LS imaging at 25 and 60−90<!--> <!-->min after injection (early and late). The observed agreement was analyzed and a concordance study was performed between the number of SNs detected with freehand SPECT and LS.</p></div><div><h3>Results</h3><p>The observed agreement in the detection of SNs between freehand SPECT and early LS was 72%; between freehand SPECT and late LS was 85%; and between early and late LS was 87%. In the concordance study, there was moderate concordance between freehand SPECT and early LS (kappa coefficient: 0.42); moderate-high concordance between freehand SPECT and late LS (kappa coefficient: 0.60); and moderate-high concordance between early and late LS (kappa coefficient: 0.70), with no significant differences between them (p-value<!--> <!-->=<!--> <!-->0.16).</p></div><div><h3>Conclusion</h3><p>Freehand SPECT showed a moderate-high concordance with conventional imaging studies and could be a valid alternative for the presurgical study of SLNB in breast cancer.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 79-83"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J. Ribera-Perianes , M. Vega , X. Cases Moreno , J. Cordón , J. Cortés Gracia , P. Paredes , N. Sánchez-Izquierdo , A. Perissinotti , D. Fuster Pelfort , S. Vidal-Sicart
{"title":"Multidisciplinary radio-guided surgery team: Alternative to change the current paradigm","authors":"J. Ribera-Perianes , M. Vega , X. Cases Moreno , J. Cordón , J. Cortés Gracia , P. Paredes , N. Sánchez-Izquierdo , A. Perissinotti , D. Fuster Pelfort , S. Vidal-Sicart","doi":"10.1016/j.remnie.2024.02.006","DOIUrl":"10.1016/j.remnie.2024.02.006","url":null,"abstract":"<div><h3>Introduction</h3><p>Given the constant increase in the healthcare demand for examinations related to radio-guided surgery (RGS), our hospital adopted new professional profiles in the RGS team, in order to partially reduce the time spent by nuclear medicine physicians on this task.</p></div><div><h3>Aim</h3><p>To analyze the process of incorporating the profiles of Diagnostic Imaging Technician (DIT) and Sentinel Node Referent Nurse (SNRN), evaluating their deployment in the procedures linked to the technique.</p></div><div><h3>Material and methods</h3><p>Analysis of RGS activity during the period 2018–2022, focusing on pre-surgical and surgical procedures related to breast cancer (BC) and malignant melanoma (MM), as they are those pathologies on which the transfer of care competencies was concentrated. Chronological evolution of the competencies assumed by the different profiles during their integration into the RGS team.</p></div><div><h3>Results</h3><p>RGS's healthcare activity during the analyzed period experienced an increase of 109%. BC and MM were the pathologies that accounted for by far the greatest demand for care. The transfer of competencies in these two pathologies occurred in a progressive and staggered manner, with 74% (460/622) of the administration phase being carried out by the SNRN and 64% (333/519) of the surgeries by the DIT in 2022.</p></div><div><h3>Conclusions</h3><p>The creation of a multidisciplinary RGS team that includes different professional profiles (nuclear medicine physician [MN], ERGC and TSID) is an effective strategy to respond to the increase in the complexity and number of all procedures related to RGS.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 91-99"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139934950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.R. Garcia, M. Kauak, A. Compte, P. Bassa, E. Llinares, E. Valls, E. Riera
{"title":"Detection of internal mammary chain infiltration in breast cancer patients by [18F]FDG PET/MRI. Therapy implications","authors":"J.R. Garcia, M. Kauak, A. Compte, P. Bassa, E. Llinares, E. Valls, E. Riera","doi":"10.1016/j.remnie.2023.10.004","DOIUrl":"10.1016/j.remnie.2023.10.004","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the detection rate and therapeutic implication of the infiltration of the internal mammary chain (IMCI) by [<sup>18</sup>F]FDG PET/MRI for staging of patients with breast cancer.</p></div><div><h3>Methods</h3><p>Prospective study including 41 women with breast cancer (stage ≥ IIB) staged by [<sup>18</sup><span>F]FDG PET/MR. Two-phase exam: breast imaging (prone), whole-body (supine).</span></p><p><span>TNM stage assessed by peer consensus with Nuclear Medicine and </span>Radiology<span> specialists. Study of the afferent vessel (AV) to IMC by breast MRI. IMCI was correlated with age, AV-IMC, T stage, breast quadrants, axillary and distant infiltration.</span></p><p>Therapeutic re-evaluation by a multidisciplinary committee.</p></div><div><h3>Results</h3><p>IMCI detection rate of 34% (14/41), with 8/14 patients under 55 years of age. All 14 patients with IMCI showed AV-IMC, 6 of them (43.9%) without VA-axillary. Of 27/41 patients without IMCI, in 13 (48.1%) only AV-axillary was found, in the remaining 14 (51.9%), AV-axillary and AV-IMC was found.</p><p>In 57% (8/14) tumours were multicentric and 42% (6/14) focal, in inner quadrants in 4/6 (66.7%).</p><p>In 1/14 patient (7.1%) only IMCI was found, in 9/14 (64.3%) axillary and IMC, in 4/14 patients (28.6%) distant lesions were detected.</p><p>Committee re-evaluation: no further treatment in 27/41 patients (65.8%), thoracic radiotherapy in 10/41 patients (24.4%), systemic therapy in 4/41 patients (9.7%).</p></div><div><h3>Conclusion</h3><p>Our detection rate of IMCI in breast cancer staging by [<sup>18</sup>F]FDG PET/MR was 34%.</p><p>Related factors were age, multicentric tumours, inner quadrants, detection of AV-IMC, NM staging.</p><p>The evidence of IMCI allowed tailored therapy, with thoracic radiotherapy implementation in 24.4% of patients.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 73-78"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49686908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Salgado-Garcia , A. Moreno-Ballesteros , P. Guardia-Jimena , E. Sanchez-de-Mora , A.C. Rebollo-Aguirre , A. Ramirez-Navarro , A. Santos-Bueno , A. Jimenez-Heffernan
{"title":"Role of the clinical radiopharmacist in patient safety during myocardial perfusion imaging with vasodilator stress agents","authors":"C. Salgado-Garcia , A. Moreno-Ballesteros , P. Guardia-Jimena , E. Sanchez-de-Mora , A.C. Rebollo-Aguirre , A. Ramirez-Navarro , A. Santos-Bueno , A. Jimenez-Heffernan","doi":"10.1016/j.remnie.2023.12.005","DOIUrl":"10.1016/j.remnie.2023.12.005","url":null,"abstract":"<div><h3>Aim</h3><p>To assess the radiopharmacist’s role in a multidisciplinary team focused on the contraindications of regadenoson<span><span> in order to ensure the safe use of pharmacologic vasodilator stress agents </span>in patients undergoing SPECT-MPI.</span></p></div><div><h3>Methods</h3><p>We ambispectively studied its safe use in 1905 patients (54.1% female, mean age: 66.6<!--> <!-->±<!--> <span>11.7 years, range: 20–95 years). Sex, age, medical history<span>, medications, drug allergies, and contraindications for stress testing were registered together with recommendations for the nuclear physician in charge.</span></span></p></div><div><h3>Results</h3><p><span><span><span>Detected contraindications and corresponding recommendations were as follows: risk factors for QTc interval prolongation 7.5% – measurement of QTc interval previously to test and monitor ECG; prior stroke or </span>TIA 4.2% – consider </span>carotid stenosis assessment; salicylates/sulfonamides allergy 3.1% – use </span><sup>99m</sup><span><span><span>Tc-sestamibi; epilepsy or risk factors for seizures 2.4% – use of adenosine or reconsider test indication; systemic </span>corticosteroid therapy<span> for severe COPD 1.3% – reassessment of patient’s condition; </span></span>acute exacerbation of COPD<span><span> 0.8% – defer test until acute episode is over; severe asthma 0.4% – do not perform test; </span>methylxanthine<span> ingestion 0.3% – avoid consumption previously; other 6.1% – evaluation of other contraindications. No contraindications were detected in 73.6% of patients. The test was canceled due to absolute contraindications in 2.9% of the requests.</span></span></span></p></div><div><h3>Conclusions</h3><p>Working in a systematic way, the radiopharmacist was able to detect a high number of issues related to regadenoson, with one out of four patients presenting some clinical contraindication. The recommendations given by the radiopharmacist were well accepted by the nuclear physicians who changed their approach contributing to increase the safety of patients referred for MPI.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 84-90"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139111408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhenyan Ye , Yutang Yao , Jun Yin , Ying Kou , Meng Zhao , Zhuzhong Cheng
{"title":"Detection of occult neoplasia in a patient with dermatomyositis using [18F]AlF-NOTA-FAPI-04 and 18F-FDG PET/CT imaging","authors":"Zhenyan Ye , Yutang Yao , Jun Yin , Ying Kou , Meng Zhao , Zhuzhong Cheng","doi":"10.1016/j.remnie.2023.12.004","DOIUrl":"10.1016/j.remnie.2023.12.004","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 119-120"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139072481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}