S. Abouzian , D.A. López-Mora , A. Fernández-León , C. Facundo , P. Stefaneli , A. Flotats
{"title":"The added value of [18F]fluorocholine PET/TC in the assessment of secondary or tertiary hyperparathyroidism","authors":"S. Abouzian , D.A. López-Mora , A. Fernández-León , C. Facundo , P. Stefaneli , A. Flotats","doi":"10.1016/j.remnie.2024.500005","DOIUrl":"10.1016/j.remnie.2024.500005","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500005"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140759555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Controversy in the initial nodal staging of rectal cancer (MRI or PET/CT?)","authors":"Elena López Llobet , Mónica Coronado Poggio , Carmen Lancha Hernández , Carmen Martín Hervás , Daniela Travaglio Morales , Domenico Monachello Araujo , Sonia Rodado Marina , Luís Domínguez Gadea","doi":"10.1016/j.remnie.2024.500004","DOIUrl":"10.1016/j.remnie.2024.500004","url":null,"abstract":"<div><h3>Objective</h3><p>To compare the usefulness of MRI and PET/CT in nodal staging (N) of patients with locally advanced rectal cancer (LARC).</p></div><div><h3>Material and methods</h3><p>Retrospective study of patients with LARC, who completed their initial staging with PET/CT, between January-20 and March-23. Regional nodes were assessed, and N was determined using both techniques according to TNM criteria. Concordance between MRI and PET/CT was analyzed. The accuracy of both techniques was calculated for those patients who underwent direct surgery. Non-regional pelvic lymph nodes were evaluated by both modalities.</p></div><div><h3>Results</h3><p>Among the 73 patients, 48 were ultimately diagnosed with a locally advanced stage. Of these, 39 underwent neoadjuvant treatment (chemoradiotherapy) followed by surgery, and 9 direct surgery. In 25, the PET/CT extension study revealed distant disease, leading to systemic treatment. Weak concordance was observed between MRI and PET/CT in determining N (k<!--> <!-->=<!--> <!-->0.286; p<!--> <!--><<!--> <!-->0.005). Out of 73 patients, 31(42%) exhibited concordance, and 42(58%) showed discordance. In 83% of the discordant cases, MRI overstaged compared to PET/CT, with 17 cases indicating nodal involvement (N+) by MRI and N0 by PET/CT. Diagnostic accuracy was 78% for both techniques. Sensitivity, specificity, positive predictive value, and negative predictive value were 80%, 75%, 80%, and 75% for MRI, and 60%, 100%, 100%, and 67%, for PET/CT. PET/CT identified pelvic metastatic adenopathies in 8 patients that were not visible/doubtful by MRI.</p></div><div><h3>Conclusions</h3><p>In the initial nodal staging of rectal cancer MRI overstages relative to PET/CT. Both modalities are complementary, PET/CT offers higher specificity and MRI higher sensitivity.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500004"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. de la Torre Fernández, M.J Tello Galán, B. Aradas Cabado, A.E. Seva Delgado, C.M. Hernández Heredia, A.J. Fernández Sánchez
{"title":"Ossification of the falx cerebri in a patient with metastatic breast cancer","authors":"S. de la Torre Fernández, M.J Tello Galán, B. Aradas Cabado, A.E. Seva Delgado, C.M. Hernández Heredia, A.J. Fernández Sánchez","doi":"10.1016/j.remnie.2024.500001","DOIUrl":"10.1016/j.remnie.2024.500001","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500001"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140788340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yuhong Liu , Huipan Liu , Zibei Wan , Yue Chen , Jianwen Zhang
{"title":"Imaging of desmoplastic small round-cell tumor on 68Ga-FAPI PET/CT","authors":"Yuhong Liu , Huipan Liu , Zibei Wan , Yue Chen , Jianwen Zhang","doi":"10.1016/j.remnie.2024.500013","DOIUrl":"10.1016/j.remnie.2024.500013","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500013"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.R. Garcia, A. Compte, L. Mont, S. Mourelo, P. Bassa, E. Riera
{"title":"Detection of salpingitis using 18F-FDG PET in a patient presenting with febrile syndrome of unknown origin","authors":"J.R. Garcia, A. Compte, L. Mont, S. Mourelo, P. Bassa, E. Riera","doi":"10.1016/j.remnie.2024.500010","DOIUrl":"10.1016/j.remnie.2024.500010","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500010"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140757749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ayşegül Aksu , Zeynep Gülsüm Güç , Kadir Alper Küçüker , Ahmet Alacacıoğlu , Bülent Turgut
{"title":"Intra and peritumoral PET radiomics analysis to predict the pathological response in breast cancer patients receiving neoadjuvant chemotherapy","authors":"Ayşegül Aksu , Zeynep Gülsüm Güç , Kadir Alper Küçüker , Ahmet Alacacıoğlu , Bülent Turgut","doi":"10.1016/j.remnie.2024.500002","DOIUrl":"10.1016/j.remnie.2024.500002","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of our study was to evaluate the contribution of 18Fluorine-Fluorodeoxyglucose Positron Emission Tomography (18F-FDG PET) radiomic data obtained from both the tumoral and peritumoral area in predicting pathological complete response (pCR) in patients with locally advanced breast cancer receiving neoadjuvant chemotherapy (NAC).</p></div><div><h3>Methods</h3><p>Female patients with a diagnosis of invasive ductal carcinoma who received NAC were evaluated retrospectively. The volume of interest (VOI) of the primary tumor (VOI-<sub>T</sub>) was manually segmented, then a voxel-thick VOI was added around VOI-<sub>T</sub> to define the peritumoral area (VOI-<sub>PT</sub>). Morphological, intensity-based, histogram and texture parameters were obtained from VOIs. The patients were divided into two groups as pCR and non-complete pathological response (npCR). A “radiomic model” was created with only radiomic features, and a “patho-radiomic model” was created using radiomic features and immunohistochemical data.</p></div><div><h3>Results</h3><p>Of the 66 patients included in the study, 21 were in the pCR group. The only statistically significant feature from the primary tumor among patients with pCR and npCR was Morphological_Compacity-<sub>T</sub> (AUC: 0.666). Between response groups, a significant difference was detected in 2 morphological, 1 intensity, 4 texture features from VOI-<sub>PT</sub>; no correlation was found between Morphological_Compacity-<sub>PT</sub> and NGTDM_contrast-<sub>PT</sub>. The obtained radiomic model’s sensitivity and accuracy values were calculated as 61.9% and 75.8%, respectively (AUC: 0.786). When HER2 status was added, sensitivity and accuracy values of the patho-radiomic model increased to 85.7% and 81.8%, respectively (AUC: 0.903).</p></div><div><h3>Conclusions</h3><p>Evaluation of PET peritumoral radiomic features together with the primary tumor, rather than just the primary tumor, provides a better prediction of the pCR to NAC in patients with breast cancer.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 3","pages":"Article 500002"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140290095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"68Ga-FAPI and 18F-FDG PET images in a patient with tuberculosis mimicking malignant tumor on CT","authors":"Zhe Zheng , Pengcheng Hu , Yu Lin, Hongcheng Shi","doi":"10.1016/j.remnie.2024.01.001","DOIUrl":"10.1016/j.remnie.2024.01.001","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 124-127"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139379087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mangas Losada, I. García Megías, X. Boulvard Chollet, L. Romero Robles, P. Garrastachu Zumarán, R. Ramírez Lasanta
{"title":"Incidental detection by 18F-FDG PET/CT of a thyroid metastasis caused by rectal adenocarcinoma","authors":"M. Mangas Losada, I. García Megías, X. Boulvard Chollet, L. Romero Robles, P. Garrastachu Zumarán, R. Ramírez Lasanta","doi":"10.1016/j.remnie.2024.02.003","DOIUrl":"10.1016/j.remnie.2024.02.003","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 115-116"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.P. Caresia , J. Jo Rosales , M. Rodríguez Fraile , A. Arçay Öztürk , C. Artigas , On behalf of the Oncology Task Force of Spanish Nuclear Medicine and Molecular Imaging Society
{"title":"PET/CT FAPI: Procedure and evidence review in oncology","authors":"A.P. Caresia , J. Jo Rosales , M. Rodríguez Fraile , A. Arçay Öztürk , C. Artigas , On behalf of the Oncology Task Force of Spanish Nuclear Medicine and Molecular Imaging Society","doi":"10.1016/j.remnie.2024.02.005","DOIUrl":"10.1016/j.remnie.2024.02.005","url":null,"abstract":"<div><p>Neoplasms are composed of malignant tumor cells, which are surrounded by other non-tumor cellular elements, in what has been defined as the microenvironment or tumor stroma. Evidence on the importance of the tumor microenvironment has not stopped growing in recent years. It plays a central role in cell proliferation, tissue invasion, angiogenesis and cell migration.</p><p>The paradigm is the family of new FAPI radiopharmaceuticals that show the density of the fibroblast activation protein (FAP) which is overexpressed in the cell membrane of activated cancer-associated fibroblasts (CAF), and its presence is related to poor prognosis.</p><p>This educational document includes the procedure for performing PET/CT FAPI, biodistribution and the main potentially clinical applications in oncology to date.</p></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"43 2","pages":"Pages 130-140"},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}