Revista espanola de medicina nuclear e imagen molecular最新文献

{"title":"Dual-Time-Point 18F-FDG PET/CT in a case of primary hepatic Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue","authors":"Runjun Yang, Zhe Zheng, Yu Lin, Hongcheng Shi","doi":"10.1016/j.remnie.2025.500105","DOIUrl":"10.1016/j.remnie.2025.500105","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500105"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The synergic effect of Multiparametric MRI and [18F]PSMA-1007 PET/CT imaging in recurrence work-up of locally advanced prostate adenocarcinoma","authors":"Schmitt D. , Schimmöller L. , Novruzov E. , Kirchner J. , Boschheidgen M. , Mamlins E. , Antke C. , Mori Y. , Antoch G. , Giesel F.L.","doi":"10.1016/j.remnie.2025.500104","DOIUrl":"10.1016/j.remnie.2025.500104","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500104"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Justification and impact of SPECT ¹²³I-FP-CIT use in the differential diagnosis and management of movement disorders (MD) in a national referral hospital","authors":"L. Canales Rodríguez ,&nbsp;M. Mitjavila Casanovas ,&nbsp;S. Ruiz Solís","doi":"10.1016/j.remnie.2025.500092","DOIUrl":"10.1016/j.remnie.2025.500092","url":null,"abstract":"<div><div>¹²³I-FP-CIT SPECT is a key tool in the differential diagnosis of movement disorders (MD), but its appropriate indication is essential to optimize resources and avoid unnecessary tests.</div></div><div><h3>Aim</h3><div>To evaluate the adequacy and impact of ¹²³I-FP-CIT SPECT in the diagnosis and management of MD according to clinical guidelines.</div></div><div><h3>Patients and methods</h3><div>Retrospective study involving 249 patients with suspected parkinsonism (PK) of uncertain origin. All underwent ¹²³I-FP-CIT SPECT and had a clinical follow-up of exceeding 12 months. Requests were classified based on their adherence to clinical guidelines. Variables analyzed included sex, age, justification for the request, management after SPECT, and final diagnosis.</div></div><div><h3>Results</h3><div>91.57% of the requests were appropriate, while 8.43% did not adhere to the guidelines. Diagnosis changed in 48.6% of cases and management in 70.68% after the scan, especially in inconclusive cases and initiation of therapy. General neurologists evaluated more cases and made more appropriate requests (96.3% vs 76.67%; p<!--> <!-->&lt;<!--> <!-->0.001). However, MD specialists, despite less appropriate use of the guidelines, achieved a higher number of conclusive diagnoses in complex cases.</div></div><div><h3>Conclusion</h3><div>¹²³I-FP-CIT SPECT has significant clinical impact when used in accordance with clinical guidelines, improving the diagnosis and management of MD. Unjustified scans reduce its utility. Collaboration between general neurologists and MD specialists is fundamental; the latter, although showing less adherence to guidelines in requesting the test, achieve a higher number of conclusive diagnoses in complex cases.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500092"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic significance of normalized distance from maximum standardized uptake value to tumor centroid on [18F]FDG PET/CT in head and neck squamous cell carcinoma","authors":"Sun-pyo Hong ,&nbsp;Sang Mi Lee ,&nbsp;Ik Dong Yoo ,&nbsp;In Young Jo ,&nbsp;Yong Kyun Won ,&nbsp;Min-Su Kim ,&nbsp;Hye Jeong Choi ,&nbsp;Jeong Won Lee ,&nbsp;Su Jin Jang","doi":"10.1016/j.remnie.2025.500103","DOIUrl":"10.1016/j.remnie.2025.500103","url":null,"abstract":"<div><h3>Objective</h3><div>The maximum [¹⁸F]FDG uptake of a cancer lesion has been found to relocate from the center to the periphery during progression. This behavior suggests that the normalized distances from the hotspot of radiotracer uptake to the tumor centroid (NHOC) and to the tumor perimeter (NHOP) could serve as novel geometric PET parameters indicative of tumor aggressiveness. This study aimed to explore the prognostic relevance of NHOC and NHOP in [¹⁸F]FDG PET/CT for predicting the response to concurrent chemoradiotherapy (CCRT) and progression-free survival (PFS) in patients with head and neck squamous cell carcinoma (HNSCC).</div></div><div><h3>Materials and Methods</h3><div>We retrospectively reviewed 116 HNSCC patients who received CCRT and were assessed with pre-treatment (PET1) and three months post-treatment PET/CT (PET2). Along with conventional PET parameters, NHOC and NHOP for primary tumors on PET1 and the percent changes in NHOC and NHOP between PET1 and PET2 were measured.</div></div><div><h3>Results</h3><div>Of all the PET1 parameters assessed, NHOC was the most effective in predicting the CCRT response, achieving an area under the receiver operating characteristic curve of 0.645. In multivariate logistic regression and survival analysis, NHOC identified as an independent predictor for both complete metabolic response (<em>P</em> = .028) and PFS (<em>P</em> = .006). In a subgroup of 46 patients exhibiting residual primary tumors on PET2, both the percent changes in NHOC (<em>P</em> = .048) and NHOP (<em>P</em> = .041) were significantly associated with PFS.</div></div><div><h3>Conclusions</h3><div>NHOC and the percent changes in NHOC and NHOP following CCRT may serve as effective [¹⁸F]FDG PET/CT parameters for predicting clinical outcomes in HNSCC patients.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500103"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A hypoallergenic solid meal for gastric emptying scintigraphy based on mediterranean diet. “One diet to empty almost everyone”","authors":"Pablo Zaragoza-Ballester ,&nbsp;Pilar Sarandeses Fernández ,&nbsp;Inmaculada González Martín ,&nbsp;Cristina Martin-Arriscado Arroba ,&nbsp;María Isabel Cabanillas Pérez ,&nbsp;Ximena Guarnizo Poma ,&nbsp;Isabel Castel de Lucas ,&nbsp;Álvaro Galiana Morón ,&nbsp;Diana Vega Pérez ,&nbsp;Ana Isabel Romero Reina ,&nbsp;María José Tabuenca Mateo ,&nbsp;Sebastián Ruiz Solís","doi":"10.1016/j.remnie.2025.500093","DOIUrl":"10.1016/j.remnie.2025.500093","url":null,"abstract":"<div><h3>Aim</h3><div>We aim to establish normal values and standardize a hypoallergenic and mediterranean diet for gastric emptying scintigraphy (GES).</div></div><div><h3>Material and methods</h3><div>In a prospective cohort of healthy volunteers, we performed GES of a [⁹⁹Tc]TcDTPA² labelled hypoallergenic meal (egg, potato, rice and olive oil). Anterior and posterior images were simultaneously acquired at 0, 30, 60, 110, 120, 130, 180, 230, 240 and 250 min. Cross-sectional analysis was performed between demographic data and gastric retention values. A score covariance analysis model was used to observer changes between measurements over time.</div></div><div><h3>Results</h3><div>50 participants (29 women) were included. Mean values and standard deviation (5–95th) for gastric retention percentages at 60, 120, 180, 240 min were 51.40 ± 8.63 (36.5–66.1), 21.66 ± 9.40 (6.5–38.2), 7.58 ± 5.77 (1.5–19.1) and 2.94 ± 2.08 (1–7.3), respectively. Male participants had a significative faster gastric emptying compared to women in practically all the acquisitions. Male participants and smoker participants generated a significative decrease of gastric retention values in generalized linear model (male coefficient –4.818, IC95% –7.24 to –2.39, <em>P</em>-value &lt; .001; and smoker coefficient of –3.484, IC95% –6.29 to –0.67, <em>P</em>-value &lt; .05).</div></div><div><h3>Conclusion</h3><div>This study standardizes and establishes normal values for GES with the first hypoallergenic solid meal based on consensus recommendations and a mediterranean diet; suitable for most patients with allergic or sensitive-conditions to other meal components.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500093"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG PET/CT beyond staging: Prognostic significance of sarcopenia and adipose tissue metabolism in esophageal carcinomas","authors":"Merve Nur Acar Tayyar ,&nbsp;Müge Öner Tamam ,&nbsp;Gündüzalp Buğrahan Babacan ,&nbsp;Mehmet Can Şahin ,&nbsp;Halim Özçevik ,&nbsp;Necla Gürdal ,&nbsp;Kadir Atakır","doi":"10.1016/j.remnie.2024.500090","DOIUrl":"10.1016/j.remnie.2024.500090","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to investigate the relationship between PET and CT parameters and sarcopenia, adipose tissue, and tumor metabolism in esophageal carcinoma (EC) and its impact on survival in EC.</div></div><div><h3>Method</h3><div>Our study included 122 EC patients who underwent PET/CT for staging. Muscle and adipose tissue characteristics were evaluated, including lumbar (L3) and cervical (C3) muscle areas, psoas major (PM) and sternocleidomastoid muscle (SCM) parameters, and PET parameters for visceral and subcutaneous adipose tissue (SAT). Sarcopenia was determined using CT images, with a threshold for muscle tissue at the L3 vertebral level, and its impact on overall survival (OS) was investigated.</div></div><div><h3>Results</h3><div>Sarcopenia was detected in 48 patients. SULmax in the primary tumor (PT) was significantly higher in sarcopenic patients (SP). The frequency of distant metastasis was higher in SP and OS was significantly lower. In the locally advanced stage, sarcopenia status decreased survival. L3, PM, C3, and SCM muscle areas were highly correlated. Subcutaneous adipose tissue SUVmax was significantly increased in SP and those with distant metastasis. Univariate analysis identified PT SULmax, PT SUVmean, PT TLG, lymph node and distant metastasis, SAT SUVmax, and sarcopenia as poor prognostic factors, while multivariate analysis confirmed BMI, distant metastasis, PT SUVmean, PT TLG as independent predictors of OS.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that sarcopenia, linked to reduced survival, correlates with primary tumor SULmax, distant metastasis, and subcutaneous tissue PET parameters, exerting a notable impact on survival, particularly in locally advanced stages. Attenuation-corrected CT can be used instead of diagnostic CT, and sarcopenia can be diagnosed using not only L3 but also C3 slices.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500090"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[18F]FDG PET/TC in the diagnosis and treatment response evaluation in a patient with systemic sarcoidosis","authors":"J.P. Suárez Fernández,&nbsp;S. Naranjo Sancho,&nbsp;M.L. Domínguez Grande,&nbsp;C. Vigil Díaz,&nbsp;N. Martín Fernández,&nbsp;F.M. González García","doi":"10.1016/j.remnie.2025.500135","DOIUrl":"10.1016/j.remnie.2025.500135","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500135"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Macrophage activation syndrome in a pediatric patient: Findings on PET/CT with 18F-FDG","authors":"J.P. Suárez Fernández,&nbsp;M. Luz Domínguez Grande,&nbsp;C. Vigil Díaz,&nbsp;B.F. Llana,&nbsp;N. Martín Fernández,&nbsp;F. Manuel González García","doi":"10.1016/j.remnie.2025.500183","DOIUrl":"10.1016/j.remnie.2025.500183","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500183"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144201228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redefining preoperative imaging-based localization of adenomas in primary hyperparathyroidism patients candidates for minimally invasive surgery","authors":"Sebastián Casanueva-Eliceiry ,&nbsp;Marti Manyalich-Blasi ,&nbsp;Arnau Farré-Melero ,&nbsp;Aida Niñerola-Baizán ,&nbsp;David Saavedra ,&nbsp;Mireia Mora-Porta ,&nbsp;Felicia A. Hanzu ,&nbsp;Aida Orois ,&nbsp;Mattia Squarcia ,&nbsp;Maite Rodrigo-Calvo ,&nbsp;Marta Tormo-Ratera ,&nbsp;Katherine Quintero-Martinez ,&nbsp;David Fuster-Pelfort ,&nbsp;Oscar Vidal-Pérez ,&nbsp;Sergi Vidal-Sicart","doi":"10.1016/j.remnie.2025.500091","DOIUrl":"10.1016/j.remnie.2025.500091","url":null,"abstract":"<div><h3>Background and objectives</h3><div>To compare the diagnostic accuracy of [¹⁸F]-Fluorocholine (FCH) PET/CT with conventional [⁹⁹mTc]Tc-MIBI scintigraphy and cervical ultrasound (USG) for the preoperative localization of hyperfunctioning parathyroid tissue (HFPT) in patients with primary hyperparathyroidism (PHPT).</div></div><div><h3>Materials and methods</h3><div>This prospective study included 90 patients diagnosed with PHPT who underwent [¹⁸F]F-CH PET/CT, [⁹⁹mTc]Tc-MIBI SPECT/CT and Neck USG. The diagnostic accuracy of each imaging modality was assessed using intraoperative findings and histopathological confirmation as the gold standard. The localization accuracy was evaluated based on specific quadrant detection, laterality, and ectopic gland identification. The study also explored the correlation between imaging findings and biochemical parameters, including preoperative and postoperative PTH and calcium levels.</div></div><div><h3>Results</h3><div>[¹⁸F]F-CH PET/CT demonstrated superior accuracy in detecting pathological parathyroid glands compared to [^99mTc]Tc-MIBI SPECT/CT and USG. [¹⁸F]F-CH PET/CT correctly identified 98.9% of patients with pathological glands, with a specific location accuracy of 93.2%, 65.9% and 38.8% for [¹⁸F]F-CH PET/CT, [^99mTc]Tc-MIBI SPECT/CT and USG, respectively.</div><div>For ectopic adenomas, FCH PET/CT achieved an accuracy of 100% (4/4), while MIBI and neck ultrasound identified these in 50% (2/4) and 0% (0/4) of cases, respectively.</div><div>There were two cases of multiglandular disease, [¹⁸F]F-CH PET/CT and [99mTc]Tc-MIBI each detected one gland in one case (50%) while USG detected none; in the other case, [¹⁸F]F-CH PET/CT and USG identified both glands (100%), and [99mTc]Tc-MIBI detected none.</div><div>Significant correlations were observed between SUVmax values from [¹⁸F]F-CH PET/CT and gland size, weight, and preoperative PTH levels.</div></div><div><h3>Conclusions</h3><div>[¹⁸F]F-CH PET/CT outperformed conventional imaging modalities in the preoperative localization of HFPT, particularly in challenging cases such ectopic or multiglandular disease. These findings support its potential as an effective and reliable imaging tool for the management of primary hyperparathyroidism.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500091"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Procedure update and interpretation guide for the brain 18F-FDG PET study","authors":"C. Vigil Díaz ,&nbsp;P. Paredes Rodríguez ,&nbsp;A. Perissinotti ,&nbsp;E. Fernando Guillén ,&nbsp;D.A. Diego Alfonso ,&nbsp;J.A. Lojo Ramírez ,&nbsp;P. Aguiar Fernández ,&nbsp;V. Camacho ,&nbsp;M. Nieves Cabrera-Martín ,&nbsp;por el grupo de Trabajo de Neuroimagen de la SEMNIM","doi":"10.1016/j.remnie.2025.500159","DOIUrl":"10.1016/j.remnie.2025.500159","url":null,"abstract":"<div><div>The increase in the prevalence of dementia in our clinical setting poses a diagnostic challenge for the Nuclear Medicine specialist. The aim of this study is to review the modifications in the procedure and to describe the usefulness of the use of brain PET with ¹⁸F-FDG in different clinical indications, both classic and emerging ones. The SEMNIM Neuroimaging working group has considered it appropriate to update the procedures available in Spanish in order to optimize the quality of this technique and the interpretation of its findings, both for the specialist in Nuclear Medicine and the rest of the professionals involved in the diagnosis and treatment of neurodegenerative diseases.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500159"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}