Revista espanola de medicina nuclear e imagen molecular最新文献

{"title":"Optimization of axillary staging in breast cancer: efficacy of sentinel lymph node biopsy and targeted axillary dissection post-chemotherapy.","authors":"Aránzazu García-Ruiz, Isabel Martínez-Rodríguez, Néstor Martínez-Amador, Francisco Javier Gómez-de la Fuente, Aida Sánchez-Salmón, Julio Jiménez-Bonilla, Maria de Arcocha-Torres, Virginia Mendi Barcina, Fátima Rodríguez-Izquierdo, Nadia Virgínia Carvalho-Duarte, María Del Pilar Botanch-Domingo, Liliana Cabrera-Portillo, Pablo David Andrade-Mejía, Angélica Clavijo-Umbarila, Remedios Quirce","doi":"10.1016/j.remnie.2025.500134","DOIUrl":"https://doi.org/10.1016/j.remnie.2025.500134","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the contribution of sentinel node biopsy using lymphoscintigraphy in breast cancer (BC) with clip-marked lymph node involvement and neoadjuvant chemotherapy (NACT) in axillary staging and reduction of potential false negatives from exclusively radiological localization.</p><p><strong>Material and methods: </strong>A retrospective study of 20 women with BC and nodal involvement marked with clip and NACT. Lymphoscintigraphy was complemented with SPECT/CT in 12 patients. The correlation between lymphoscintigraphic sentinel lymph node (SLN) and the clip-marked node was analyzed.</p><p><strong>Results: </strong>Lymphoscintigraphy detected 34 axillary SLNs. SPECT/CT showed uptake in 10 of 16 clip-marked nodes (62.5%). During surgery, 39 nodes were removed; 33 (84.6%) were SLNs, 18 with clip, and 15 without clip. One SLN was not located surgically. Six clip-marked nodes (15.3%) showed no uptake. In 8 of 20 patients (40%), drainage to a single SLN was detected; this corresponded to the clip-marked node in 5 cases (non-metastatic) and non-clip-marked nodes in 3 cases (1 metastatic). In 12 of 20 patients (60%), lymphoscintigraphy showed drainage to more than one SLN. A total of 26 SLNs were detected: 13 SLNs with clip (5 metastatic) and 13 without clip (4 metastatic). Lymphoscintigraphy detected 5 SLNs in 4 of 20 patients (20%) that did not match the clip-marked node and were metastatic. The detection and removal rate of GCL was 97% and false negative rate was 16,67%.</p><p><strong>Conclusion: </strong>Lymphoscintigraphy in BC with positive axilla before NACT detected metastases in a significant percentage of patients not identified with clip, being an essential tool for accurate axillary staging.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500134"},"PeriodicalIF":0.0,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Redefining preoperative imaging-based localization of adenomas in primary hyperparathyroidism patients candidates for minimally invasive surgery.","authors":"Parth Aphale, Shashank Dokania, Himanshu Shekhar","doi":"10.1016/j.remnie.2025.500227","DOIUrl":"https://doi.org/10.1016/j.remnie.2025.500227","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500227"},"PeriodicalIF":0.0,"publicationDate":"2025-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145246049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bilateral Lacrimal Gland MALT Lymphoma Incidentally Detected on 68Ga-DOTATATE PET/CT: An Unusual but Noticeable Finding.","authors":"Cansu Kucuker, Serkan Akin, Deniz Pinar Baran, Ekim Gumeler, Aysegul Uner, Pinar Kiratli","doi":"10.1016/j.remnie.2025.500202","DOIUrl":"https://doi.org/10.1016/j.remnie.2025.500202","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500202"},"PeriodicalIF":0.0,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145234241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastrointestinal transit scintigraphy in the evaluation of rectocele.","authors":"J R Infante, A Utrera, R Barco, M Carmona, I Gallarín, A Baena, A Martínez, C Durán, N Sicilia, J Serrano","doi":"10.1016/j.remnie.2025.500142","DOIUrl":"https://doi.org/10.1016/j.remnie.2025.500142","url":null,"abstract":"<p><strong>Aim: </strong>Rectocele can cause chronic constipation and altered quality of life. In the presence of severe symptomatology and lack of response to conservative treatment, gastrointestinal motor function should be assessed. The aim of this study was to assess the utility of gastrointestinal transit scintigraphy in this pathology, analyzing its position in international guidelines.</p><p><strong>Material and methods: </strong>We retrospectively evaluated twelve women with rectocele and chronic constipation, range of 31-74 years, referred for scintigraphic study as an assessment prior to prolapse treatment,. Defecography was altered in 12 and anorectal manometry in 8. Following international guidelines, a dose of [¹¹¹In]In-DTPA (37 m Bq) was administered together with standardized food to assess liquid gastric emptying and small-bowel and colonic transit. Areas of interest were defined in these locations to calculate the geometric center.</p><p><strong>Results: </strong>In 3 patients the radioisotopic study was normal, 3 showed a pattern of outlet obstruction, 3 colonic inertia, 2 slow small-bowel transit and 1 slow generalized transit. Thus, 50% of patients presented transit alterations not located in the rectosigmoid area.</p><p><strong>Conclusion: </strong>Scintigraphy study provided useful information for the evaluation of patients with rectocele and constipation, influencing the diagnosis and therapeutic management. It proved to be a physiological method, providing both global and regional quantitative information. Like other authors, it is considered appropriate to use the study at the same level as the tests for the assessment of defecatory dynamics.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500142"},"PeriodicalIF":0.0,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A rare case of synchronous multicentric paragangliomas detected using [⁶⁸Ga]Ga-DOTATATE PET/CT.","authors":"N A Dizdar, A Dursun, M Samsum, O Ozmen","doi":"10.1016/j.remnie.2025.500233","DOIUrl":"10.1016/j.remnie.2025.500233","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500233"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vesical displacement due to rectal distension mimicking ureteral obstruction.","authors":"H Elahifard, A Saber Tanha, M Ahmadi, M Saberifar, M J Bahonar, R Sadeghi","doi":"10.1016/j.remnie.2025.500231","DOIUrl":"10.1016/j.remnie.2025.500231","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500231"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment with [166Ho]Ho-labeled polylactic acid microspheres in a patient with giant focal nodular hyperplasia.","authors":"J J Martin-Marcuartu, J L Vercher-Conejero, B Hervás-Sanz, J Valcarcel José, L Llado Garriga, M Cortes-Romera","doi":"10.1016/j.remnie.2025.500204","DOIUrl":"10.1016/j.remnie.2025.500204","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500204"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective sentinel lymph node biopsy in breast cancer local recurrence.","authors":"L Rodríguez-Díaz, P Zaragoza-Ballester, I Torras, E Mensión, I Cebrecos, X Cases, M Vega, J Cordón, J Ribera-Perianes, S Vidal-Sicart","doi":"10.1016/j.remnie.2025.500232","DOIUrl":"10.1016/j.remnie.2025.500232","url":null,"abstract":"<p><strong>Introduction and objectives: </strong>5-10% of breast tumor patients develop local breast tumor recurrence. The absence of axillary re-staging could increase future local recurrence and mortality risk in these patients. The lymphoscintigraphy for sentinel lymph node biopsy in recurrences (rSLNB) using a radiotracer injection, can be an option to evaluate axillar status, but other factors known to alter the usual behaviour of SLN migration have to be taken into account, such as previous axillary surgery, breast surgery or adjuvant treatments. Our objective was to evaluate the relationship between these factors and the success rate of rSLNB (overall and aberrant drainage rates, metastases ratio).</p><p><strong>Materials and methods: </strong>1102 patients were retrospectively evaluated in a tertiary hospital between 10/2018-04/2022. 52 patients with ipsilateral breast tumor recurrence who underwent rSLNB were included. Demographic data, tumor characteristics, previous treatments, drainage rates and characteristics were collected and analyzed (R statistical software).</p><p><strong>Results: </strong>Overall drainage rate was 83%, in which excision was performed in 91%. Overall migration rate was significantly higher in patients with previous SLNB (92% vs 60%, p-value = 0.012) and aberrant drainage was significantly higher in patients with previous axillar lymphadenectomy (ALND) (53% vs 24%, p-value = 0.047). No statistical differences were observed in breast surgery or adjuvant radiotherapy. The percentage of positivity found was 13% (3 micrometastases and 2 macrometastases). 20% of metastases were found in aberrant drainage territories.</p><p><strong>Conclusions: </strong>rSLNB is a feasible and applicable technique in ipsilateral breast tumor recurrence, providing key information in locorregional recurrence management. A considerable percentage of metastases are located in aberrant drainage territories, which would have been missed without rSLNB. Therefore, rSLNB is essential for a correct axillary evaluation in order to trace them.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500232"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of [177Lu]Lu-PSMA-617 treatment response with [68Ga]Ga-PSMA-11 PET-derived variables and correlation of the overall survival with serum PSA and PSMA PET-based response criteria.","authors":"E Ozkan, B Demir, C Soydal, M Araz, E Dursun, N O Kucuk, Y Urun","doi":"10.1016/j.remnie.2025.500208","DOIUrl":"10.1016/j.remnie.2025.500208","url":null,"abstract":"<p><strong>Purpose: </strong>In this study we aimed to investigate prediction of response with [68Ga]Ga-PSMA PET-derived parameters and the effectiveness of RECIP criteria and PSA response in predicting survival after [177Lu]Lu-PSMA therapy.</p><p><strong>Methods: </strong>Patients who received at least 2 cycles of [177Lu]Lu-PSMA therapy were retrospectively included in the study. All lesions in the PET images were segmented and PSMA PET-based parameters were extracted. The treatment response was evaluated according to RECIP and PSA criteria. ROC analyses were performed to assess their discriminatory power in predicting response. Correlation of overall survival with RECIP and PSA-based response was evaluated using Kaplan-Meier survival analysis.</p><p><strong>Results: </strong>A total of 41 patients were included in the study. SUVmax, SUVpeak, SUVmean, qPSG-max and qPSG-mean values were significant factors in predicting PSA response. However, in predicting RECIP response (CR + PR), the AUC values for the SUV parameters were not significantly higher than 0.5. In predicting RECIP disease control (CR + PR + SD), the AUC values for SUVmax, SUVpeak, and SUVmean were 0.742(p = 0.002), 0.742(p = 0.002), and 0.722(p = 0.006). In the RECIP-responder and non-responder groups, the median survival was 33.5 and 15.2 months (p = 0.005). In patients with RECIP-disease control and progressive disease, the median survival was 25.1 and 15.2 months (p = 0.002). However, the survival difference between PSA-responder and non-responders groups did not reach significance (p = 0.127).</p><p><strong>Conclusion: </strong>PSMA PET imaging is a useful method to select patients who will most likely to benefit from [177Lu]Lu-PSMA treatment. Also, it has been shown that RECIP has significantly performed better than PSA-based response evaluation in terms of predicting overall survival.</p>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500208"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrapulmonary Castleman disease mimicking locally advanced primary lung cancer on ¹⁸F-FDG PET/CT.","authors":"D Huang, X Yang, Y Chen, J Gong","doi":"10.1016/j.remnie.2025.500213","DOIUrl":"10.1016/j.remnie.2025.500213","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500213"},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145152570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}