Revista espanola de medicina nuclear e imagen molecular最新文献_第2页

Low dose radioactive iodine ablation therapy (1.11GBq) for differentiated thyroid cancer in Western Turkey. 土耳其西部分化型甲状腺癌的低剂量放射性碘消融治疗（1.11GBq）。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-11-01 Epub Date: 2024-09-10 DOI: 10.1016/j.remnie.2024.500055

B Karasah Erkek, H Sariyildiz Gumusgoz, A Oral, B Yazici, A Akgun

{"title":"Low dose radioactive iodine ablation therapy (1.11GBq) for differentiated thyroid cancer in Western Turkey.","authors":"B Karasah Erkek, H Sariyildiz Gumusgoz, A Oral, B Yazici, A Akgun","doi":"10.1016/j.remnie.2024.500055","DOIUrl":"10.1016/j.remnie.2024.500055","url":null,"abstract":"Objective: Ablation therapy is employed in low-risk differentiated thyroid cancer (DTC) cases to facilitate patient monitoring by reducing thyroglobulin (Tg) levels to measurable levels below after surgery by eliminating residual thyroid tissue. However, there is still uncertainty about the minimum activity dose required for effective ablation. Opting for low-dose [131I]-NaI for ablation offers several advantages for both patients and healthcare services. Particularly in this tumor group with a high life expectancy (approximately 90-95 % at 10 years), [131I]-NaI treatment should not pose a risk to the patient's post-treatment life and should not compromise their quality of life. However, there is a need for a well-defined identification of factors predicting successful ablation.Methods: Clinical data, laboratory findings, and imaging tests of 287 patients with low-dose 1110 MBq (30 mCi) [131I]-NaI ablation therapy for DTC were retrospectively reviewed. Post-ablation imaging and laboratory findings categorized ablation success/failure. The successful ablation group was determined according to the excellent response criteria outlined in ATA criteria. Relationships between clinical, pathological findings, biochemical common variables, and treatment failure were analyzed.Results: An excellent response was achieved in 77% of the entire group according to ATA criteria post-ablation. Male gender and high Tg levels on the day of ablation (Tg cut-off: 10 ng/mL and 5.35 ng/mL) were associated with unsuccessful ablation.Conclusions: Our results indicate that a 1110MBq (30mCi) ablation dose is sufficient to achieve an excellent response in most low-risk DTC cases 6-12 months later. When selecting the dose for ablation, besides the histological markers mentioned in guidelines and age, we observed that stimulated Tg values and gender may be important in predicting ablation success.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessment of pulmonary nodules using [¹⁸F]-FDG PET/CT in deep inspiration breath-hold. 在深吸气时使用 [18F]-FDG PET/CT 评估肺结节。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-29 DOI: 10.1016/j.remnie.2024.500074

M S Casallas Cepeda, S S Cortes, I G Fernández, J O Rincón, L R Berenguer, E J Ardila Manjarrez, J J Ardila Mantilla, V C Morales, J G Cruz, D Z Rodriguez, A M Hualde, J E Montalvá Pastor, S Á Lara, J C Alonso Farto

{"title":"Assessment of pulmonary nodules using [18F]-FDG PET/CT in deep inspiration breath-hold.","authors":"M S Casallas Cepeda, S S Cortes, I G Fernández, J O Rincón, L R Berenguer, E J Ardila Manjarrez, J J Ardila Mantilla, V C Morales, J G Cruz, D Z Rodriguez, A M Hualde, J E Montalvá Pastor, S Á Lara, J C Alonso Farto","doi":"10.1016/j.remnie.2024.500074","DOIUrl":"10.1016/j.remnie.2024.500074","url":null,"abstract":"The characterization of pulmonary nodules (PN) is a primary indication for [18F]-FDG PET/CT. However, respiratory movements hinder this characterization, especially for PN located in the lower lobes. Various methods have been developed to improve image resolution.Objective: Our objective was to compare the diagnostic efficacy of [18F]-FDG PET/CT in deep inspiration breath-hold (DIBH) versus free-breathing corrected by software, in the evaluation of PN.Methods: We prospectively analyzed 51 patients to assess PN using [18F]-FDG PET/CT in DIBH and free-breathing corrected by software. A total of 84 nodules with an average size of 10 mm were analyzed, with pathological anatomy or medical treatment decisions by a multidisciplinary tumor board used as reference.Results: A total of 84 PN were evaluated, comparing those in DIBH versus free-breathing, finding statistically significant differences in SUVmax values (P < .05) (mean SUVmax 3.7 in free-breathing vs. 5.33 in DIBH). When analyzed by location in lobes, we did not find statistically significant differences, though there was a trend towards higher SUVmax values in the lower lobes. [18F]-FDG PET/CT in DIBH showed high sensitivity (95%) and negative predictive value (NPV) (92%), indicating it may be a promising tool for PN characterization.Conclusions: The acquisition of [18F]-FDG PET/CT in DIBH significantly improves the sensitivity and diagnostic efficacy in the assessment of PN. Although no statistically significant differences were found based on location, there is a potential benefit for the lower lobes. These findings could support its use in clinical practice.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142559909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of staging using [⁶⁸Ga]Ga-PSMA-11 PET/CT and histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy and pelvic lymph node dissection. 使用[68Ga]Ga-PSMA-11 PET/CT对接受根治性前列腺切除术和盆腔淋巴结清扫术治疗的中高危前列腺癌患者进行分期与组织病理学结果的比较。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-28 DOI: 10.1016/j.remnie.2024.500076

J J Rosales, V Betech Antar, F Mínguez, F Pareja, F Guillén, E Prieto, G Quincoces, F D Caballero, B Miñana, J L Pérez-Gracia, M Rodríguez-Fraile

{"title":"Comparison of staging using [68Ga]Ga-PSMA-11 PET/CT and histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy and pelvic lymph node dissection.","authors":"J J Rosales, V Betech Antar, F Mínguez, F Pareja, F Guillén, E Prieto, G Quincoces, F D Caballero, B Miñana, J L Pérez-Gracia, M Rodríguez-Fraile","doi":"10.1016/j.remnie.2024.500076","DOIUrl":"10.1016/j.remnie.2024.500076","url":null,"abstract":"Objective: To evaluate the diagnostic accuracy of [68Ga]Ga-PSMA-11 PET/CT (PET-PSMA) in local and loco-regional nodal staging compared with histopathological results in intermediate- and high-risk prostate cancer patients treated with radical prostatectomy (RP) and pelvic lymph node dissection (PLND).Materials y methods: A total of 122 intermediate- and high-risk prostate cancer (PCa) patients staged with PET-PSMA and treated with RP (36/122) and RP plus PLND (86/122) from December 2018 to December 2023 were included. Visual and semiquantitative analysis findings using the SUVmax of the molecular imaging were correlated with histopathological results.Results: The primary tumor was visible by PET-PSMA in 96.7% of the patients. A positive correlation was found between PSA levels and SUVmax (Spearman's r: 0.303, p < 0.001). PET-PSMA detected nodal involvement in 25/89 patients (28.08%). The sensitivity, specificity, and diagnostic accuracy of PET-PSMA for detecting nodal involvement were 75%, 82.2%, and 80.9%, respectively. Patients with PSA levels >20 ng/mL, Gleason score ≥7b, ISUP grade >2, and extracapsular extension showed significantly higher SUVmax values. No differences were observed in SUVmax between risk groups or in other histopathological variables.Conclusions: PET-PSMA is an effective tool for the initial staging of intermediate- and high-risk PCa. SUVmax values were significantly higher in patients with unfavorable clinical features.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142549903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Secondary intestinal amyloidosis visualized on a scintigraphy with [^m99Tc]Tc-HMDP. 使用[m99Tc]Tc-HMDP进行闪烁扫描时发现的继发性肠道淀粉样变性。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-22 DOI: 10.1016/j.remnie.2024.500070

S Bondia-Bescós, I E Sánchez-Rodríguez, A Palomar-Muñoz, P Notta, M Cortés-Romera, L M Gràcia-Sánchez

引用次数: 0

Complete metabolic remission of widespread blastic plasmacytoid dendritic cell neoplasm after treatment. 广泛的浆细胞性树突状细胞肿瘤经治疗后完全代谢缓解。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-22 DOI: 10.1016/j.remnie.2024.500040

N Filizoglu, S Ozguven

引用次数: 0

Mediastinal lymph node metastases from prostate cancer: Enhanced diagnostic accuracy of PET/CT with ¹⁸F-DCFPyL versus ¹⁸F-choline. 前列腺癌纵隔淋巴结转移：使用 18F-DCFPyL 和 18F-choline 的 PET/CT 可提高诊断准确性。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-22 DOI: 10.1016/j.remnie.2024.500063

R M Angulo Amorese, F J Pena Pardo, J C Rodríguez Gómez, N Disotuar Ruiz, M P Talavera Rubio, V M Poblete García

引用次数: 0

¹⁸F-FDG PET/CT in the staging, therapeutic evaluation and follow-up of prostatic sarcoma. 18F-FDG PET/CT 在前列腺肉瘤分期、治疗评估和随访中的应用。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-10-22 DOI: 10.1016/j.remnie.2024.500039

I Martínez-Rodríguez, F Gómez-de la Fuente, A Sánchez-Salmón, M Pombo-López, A Bota-Bota, R Quirce

引用次数: 0

Radioactive seed localization technique with 125-I in inguinal endometriosis. 腹股沟子宫内膜异位症的 125-I 放射粒子定位技术。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-09-29 DOI: 10.1016/j.remnie.2024.500069

L Rodríguez-Díaz, E García, C de Guirior, R Salvador, J Ribera-Perianes, S Vidal-Sicart

引用次数: 0

Peritoneal scintigraphy and SPECT/TC in the diagnosis of leaks in patients on peritoneal dialysis. 腹膜闪烁扫描和 SPECT/TC 在腹膜透析患者渗漏诊断中的应用。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-09-29 DOI: 10.1016/j.remnie.2024.500067

D Tercero Garrido, M V Guiote Moreno, C Rodelo-Haad, P I Contreras Puertas, S Soriano Cabrera, M D Albalá González

{"title":"Peritoneal scintigraphy and SPECT/TC in the diagnosis of leaks in patients on peritoneal dialysis.","authors":"D Tercero Garrido, M V Guiote Moreno, C Rodelo-Haad, P I Contreras Puertas, S Soriano Cabrera, M D Albalá González","doi":"10.1016/j.remnie.2024.500067","DOIUrl":"10.1016/j.remnie.2024.500067","url":null,"abstract":"Objective: To assess the usefulness of peritoneal cavity scintigraphy and the contribution of SPECT/CT in patients on peritoneal dialysis with suspected leak.Methodology: An observational case series study is carried out. It consists of a longitudinal, retrospective and descriptive study. 11 patients on peritoneal dialysis were studied and it was realiced a peritoneal cavity scintigraphy test and SPECT/CT to evaluate a peritoneal leak.Results: In 54,5% of the patients, a positive study of peritoneal leak was obtained. The most frequent localitations were in the abdominal wall at the catheter entry level and the inguinal hernia. In the cases with sintomatology like pain and celullitis of the subcutaneous tract of the cateter the frequent of leak was 100%. There was a change in therapeutic management in patients with a positive study. There was not relevant changes in initial dialysis regimen in patients with a negative study. In this cases, except for one patient who required hemodialysis, all patients experienced clinical improvement.Conclusions: Peritoneal scintigraphy and SPECT/CT study are non-invasive techniques that allow an adequate diagnosis and subsequent management of peritoneal leak.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use of propranolol in [¹⁸F] FDG-PET/CT for differential diagnosis of brown fat in patient with a history of adenocarcinoma of the uterine cervix. 在[18F] FDG-PET/CT 中使用普萘洛尔对有子宫颈腺癌病史的患者的棕色脂肪进行鉴别诊断。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2024-09-29 DOI: 10.1016/j.remnie.2024.500068

A Garcia Garcia, A P Caresia Aróztegui, S Martínez Román

引用次数: 0