Revista espanola de medicina nuclear e imagen molecular最新文献_第2页

Multifocal osteonecrosis in pediatric-onset systemic lupus erythematosus. 小儿起病系统性红斑狼疮的多灶性骨坏死。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-22 DOI: 10.1016/j.remnie.2025.500206

H Elahifard, M H Samadi, E Askari, F Taheri, S Abedi, M Vahedi

引用次数: 0

Detection of extremely rare testicular cancer metastasis to the duodenum with ¹⁸F-FDG PET/CT. 极罕见睾丸癌转移至十二指肠的18F-FDG PET/CT检测。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-17 DOI: 10.1016/j.remnie.2025.500230

Muhammet Fatih Beytur, Enver Yarıkkaya, Sevim Baykal Koca, Göksel Alçın, Elife Akgün, Erkan Erkan, Esra Arslan

引用次数: 0

Prognostic value of [¹⁸F]FDG PET/CT in follicular lymphoma. [18F]FDG PET/CT对滤泡性淋巴瘤的预后价值。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-12 DOI: 10.1016/j.remnie.2025.500229

A Díaz Silván, D Cabello García, L F Otón Sánchez

{"title":"Prognostic value of [18F]FDG PET/CT in follicular lymphoma.","authors":"A Díaz Silván, D Cabello García, L F Otón Sánchez","doi":"10.1016/j.remnie.2025.500229","DOIUrl":"10.1016/j.remnie.2025.500229","url":null,"abstract":"Objective: To determine the prognostic value of [18F]FDG PET/CT in follicular lymphoma (FL) patients in our routine clinical practice.Material and methods: Retrospective study of FL patients assessed with PET/CT in our centre from 01/06/2008 to 01/06/2020. This study aimed to investigate the prognostic value of quantitative parameters (MTV, TLG, ΔSUV max) and qualitative criteria (Lugano classification), and its relationships with progression-free survival (PFS) and overall survival (OS).Results: Among patients with available staging PET/CT, the 5-year OS was 90.4% for those with lower MTV and 89.7% for those with higher MTV (p = 0.3). The PFS was 77.6% for those with lower MTV and 53.2% for those with higher MTV (p = 0.001). TLG yielded statistically similar results. A ΔSUV max ≥ 66% was associated with higher OS and PFS at 5 years, at both interim and final PET/CT studies (iPET and fPET). The 5-year OS for patients with complete metabolic response was 86.3% in iPET and 89.0% in fPET, compared to 84.1% and 79.0%, respectively, for those positive in iPET (p = 0.3) and fPET (p = 0.1). The 5-year PFS for patients with complete metabolic response was 76.9% in iPET and 73.1% in fPET, compared to 58.7% and 62.2%, respectively, for those positive in iPET (p = 0.04) and fPET (p = 0.09).Conclusions: PET/CT is valuable as a prognostic factor in FL, both during staging (providing parameters with independent prognostic value such as MTV and TLG) and during and after treatment (as it correlates with survival).","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500229"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145067158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute descending necrotizing mediastinitis as a complication of a retropharyngeal abscess: Diagnosis with [¹⁸F]FDG PET/CT. 急性下行坏死性纵隔炎作为咽后脓肿的并发症：用FDG PET/CT诊断[18F]。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-12 DOI: 10.1016/j.remnie.2025.500234

P Dauden-Onate, L F León-Ramírez, G Cuesta-Domingo, M Vaillant-Lopez, C González-Roiz, M N Cabrera-Martín

引用次数: 0

A dynamic nomogram model integrating serum phosphorus and longest diameter enhances diagnostic accuracy of 99mTc-MIBI imaging for parathyroid adenoma patients with elevated parathyroid hormone. 结合血清磷和最长直径的动态nomogram模型提高了99mTc-MIBI对甲状旁腺腺瘤伴甲状旁腺激素升高患者的诊断准确性。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-12 DOI: 10.1016/j.remnie.2025.500228

L Zheng, B Wang, T Wu, W Qu

{"title":"A dynamic nomogram model integrating serum phosphorus and longest diameter enhances diagnostic accuracy of 99mTc-MIBI imaging for parathyroid adenoma patients with elevated parathyroid hormone.","authors":"L Zheng, B Wang, T Wu, W Qu","doi":"10.1016/j.remnie.2025.500228","DOIUrl":"10.1016/j.remnie.2025.500228","url":null,"abstract":"Background: Parathyroid adenoma (PA) is the most common cause of primary hyperparathyroidism (PHPT). 99mTc-methoxyisobutylisonitrile (99mTc-MIBI) imaging is widely applied in PA diagnosis and location. However, since the individual heterogeneity and adenoma function differences, the diagnostic efficacy of 99mTc-MIBI imaging is limited, which often leads to misdiagnosis and even mistreatment of PA.Methods: In the present study, we established a novel dynamic nomogram model to assist the nuclear imaging diagnosis of PA. A total of 96 PA patients, with 65 cases in the positive group and 31 cases in the negative group, were enrolled for further analyzing.Results: Univariate analysis showed there were no statistically significant differences between the two groups in terms of gender, age, and adenoma location. The patients in the positive group had significantly higher levels in PTH, serum calcium, longest diameter and shortest diameter of adenoma, compared to those in the negative group. But the serum phosphorus levels were lower in the positive group than in the negative group. Binary logistic regression analysis indicated that serum phosphorus and adenoma longest diameter were independent positive predictors. The dynamic nomogram model was generated by R software and logistic regression analysis (https://zhenglong-1988.shinyapps.io/dynnomapp/). The receiver operating characteristics curve (ROC curve) analysis revealed that the cut-off probability for the model to diagnose PA was 59.1%, with AUC values of 0.965.Conclusions: The novel dynamic nomogram diagnostic model integrating serum phosphorus levels and longest diameter could effectively improve the diagnostic accuracy of radionuclide imaging for PA.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500228"},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145067166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment with radionuclide-labeled peptides in refractory meningiomas: Updated review and clinical perspectives. 放射性核素标记肽治疗难治性脑膜瘤：最新综述和临床前景。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-05 DOI: 10.1016/j.remnie.2025.500218

E Abou Jokh Casas, J L Vercher Conejero, A Repetto, P Bello Arques, T Cambil Molina, A Rodriguez Gasén, J A Vallejo Casas

{"title":"Treatment with radionuclide-labeled peptides in refractory meningiomas: Updated review and clinical perspectives.","authors":"E Abou Jokh Casas, J L Vercher Conejero, A Repetto, P Bello Arques, T Cambil Molina, A Rodriguez Gasén, J A Vallejo Casas","doi":"10.1016/j.remnie.2025.500218","DOIUrl":"10.1016/j.remnie.2025.500218","url":null,"abstract":"The use of theragnostics in nuclear medicine has significantly advanced, particularly peptide receptor radionuclide therapy (PRRT) in neuroendocrine tumors. Meningiomas often overexpress somatostatin receptors (SSTR), making them potential candidates for PRRT. However, the lack of large-scale standardized trials limits its clinical application. Meningiomas are the most common primary intracranial tumors; the treatment of choice for which is surgical resection or, if that's not possible, radiotherapy. However, some cases are refractory to standard treatments, leading to the exploration of other therapeutic options, such as targeted therapy with radioligands. Studies have demonstrated promising results with [177Lu]Lu-DOTATATE in meningiomas expressing SSTR2, improving progression-free survival (PFS) in refractory cases. Current evidence suggests that PRRT is a viable option for refractory meningiomas with high SSTR expression. However, further clinical trials are needed to establish standardized protocols, optimize patient selection criteria, and explore combination therapy strategies to improve outcomes. This review highlights the mechanisms, clinical applications, and future perspectives of [177Lu]Lu-DOTATATE in meningiomas, providing insights into its expanding role in this pathology.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500218"},"PeriodicalIF":0.0,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[18F]FDG PET/CT in pulmonary Castleman's disease. [18F]肺Castleman病的FDG PET/CT诊断。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-04 DOI: 10.1016/j.remnie.2025.500209

H Y Zhang, X Yang

引用次数: 0

Metabolic alterations on brain [¹⁸F]FDG PET in a case of postcoital transient global amnesia. 1例性交后短暂性全身性遗忘的FDG - PET脑代谢改变[18F]。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-04 DOI: 10.1016/j.remnie.2025.500203

F Sebastián Palacid, B Pérez López, N Álvarez Mena, C Riola Parada, C Gamazo Laherrán, R Ruano Pérez

引用次数: 0

PET/CT in breast cancer. 乳腺癌的PET/CT。

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-04 DOI: 10.1016/j.remnie.2025.500139

J F Bastidas, M Martínez de Bourio-Allona, A Roteta Unceta Barrenechea, M Rodríguez-Fraile, L Sancho

引用次数: 0

Predictive value of metastatic distribution patterns on [⁶⁸Ga]Ga-PSMA PET/CT for [¹⁷⁷Lu]Lu-PSMA therapy. [68Ga]Ga-PSMA PET/CT转移分布模式对[177Lu]Lu-PSMA治疗的预测价值

Revista espanola de medicina nuclear e imagen molecular Pub Date : 2025-09-01 DOI: 10.1016/j.remnie.2025.500205

Y B Cayirli, U Elboga, I Dogan

{"title":"Predictive value of metastatic distribution patterns on [68Ga]Ga-PSMA PET/CT for [177Lu]Lu-PSMA therapy.","authors":"Y B Cayirli, U Elboga, I Dogan","doi":"10.1016/j.remnie.2025.500205","DOIUrl":"10.1016/j.remnie.2025.500205","url":null,"abstract":"Objective: This study aimed to assess the predictive value of metastatic distribution patterns on 68Ga-PSMA-11 PET/CT in patients with chemotherapy- and castration-resistant prostate cancer undergoing ¹⁷⁷Lu-PSMA-617 radioligand therapy.Materials and methods: A retrospective analysis was conducted on 48 patients who received ¹⁷⁷Lu-PSMA-617 therapy between April 2019 and August 2023. Demographic, clinical, and laboratory data, along with pre- and post-treatment 68Ga-PSMA-11 PET/CT images, were evaluated for associations with molecular response and progression. Whole-body PET/CT segmentation was performed using METAVOL software. Treatment response was classified using RECIP 1.0 criteria, and predictive values were analyzed using SPSS 22.0, with statistical significance set at p < 0.05.Results: Based on RECIP 1.0 criteria, 58.3% (n = 28) responded to therapy, while 41.7% (n = 20) did not. Disease progression was observed in 29.2% (n = 14), and 70.8% (n = 34) showed no progression. Molecular response was significantly associated with parotid SUVmean (OR = 1.137, p = 0.047) and highest miM1 stage (OR = 0.241, p = 0.046). Molecular progression was significantly associated with lymph node metastasis (OR = 0.144, p = 0.006), bone-only metastasis (OR = 4.333, p = 0.030), ln/metTL-PSMA ratio (OR = 0.070, p = 0.042), b/metTL-PSMA ratio (OR = 13.085, p = 0.040), and TL-PSMA-based lymph node dominance over bone metastases (OR = 0.385, p = 0.044).Conclusion: This study highlights the predictive value of metastatic burden distribution on 68Ga-PSMA PET/CT in determining treatment outcomes of ¹⁷⁷Lu-PSMA therapy.","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500205"},"PeriodicalIF":0.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144995038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0