R González Couto, C M Carballo Menayo, A Sanfiel Delgado, F J González Hernández, S Cifuentes Díaz, M C Isla Gallego
{"title":"Selective sentinel lymph node biopsy in a tumor on axillary ectopic breast tissue.","authors":"R González Couto, C M Carballo Menayo, A Sanfiel Delgado, F J González Hernández, S Cifuentes Díaz, M C Isla Gallego","doi":"10.1016/j.remnie.2025.500207","DOIUrl":"10.1016/j.remnie.2025.500207","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500207"},"PeriodicalIF":0.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S de la Torre Fernández, A K Minguillan Van Kapel, B Aradas Cabado, M J Tello Galán, A E Seva Delgado, C M Hernández Heredia
{"title":"Portal of entry for Streptococcus gallolyticus in infective endocarditis.","authors":"S de la Torre Fernández, A K Minguillan Van Kapel, B Aradas Cabado, M J Tello Galán, A E Seva Delgado, C M Hernández Heredia","doi":"10.1016/j.remnie.2025.500210","DOIUrl":"10.1016/j.remnie.2025.500210","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500210"},"PeriodicalIF":0.0,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Önner, M N Calderon-Tobar, L Perktaş, F Yilmaz, G Kara Gedіk
{"title":"Re: Response to the letter regarding \"Evaluating the Role of Sarcopenia and [18F]FDG PET/CT Parameters in Prognosis of Pancreatic Ductal Adenocarcinoma\".","authors":"H Önner, M N Calderon-Tobar, L Perktaş, F Yilmaz, G Kara Gedіk","doi":"10.1016/j.remnie.2025.500164","DOIUrl":"10.1016/j.remnie.2025.500164","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":" ","pages":"500164"},"PeriodicalIF":0.0,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dual-Time-Point 18F-FDG PET/CT in a case of primary hepatic Extranodal Marginal Zone Lymphoma of Mucosa-associated Lymphoid Tissue","authors":"Runjun Yang, Zhe Zheng, Yu Lin, Hongcheng Shi","doi":"10.1016/j.remnie.2025.500105","DOIUrl":"10.1016/j.remnie.2025.500105","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500105"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Schmitt D. , Schimmöller L. , Novruzov E. , Kirchner J. , Boschheidgen M. , Mamlins E. , Antke C. , Mori Y. , Antoch G. , Giesel F.L.
{"title":"The synergic effect of Multiparametric MRI and [18F]PSMA-1007 PET/CT imaging in recurrence work-up of locally advanced prostate adenocarcinoma","authors":"Schmitt D. , Schimmöller L. , Novruzov E. , Kirchner J. , Boschheidgen M. , Mamlins E. , Antke C. , Mori Y. , Antoch G. , Giesel F.L.","doi":"10.1016/j.remnie.2025.500104","DOIUrl":"10.1016/j.remnie.2025.500104","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500104"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Canales Rodríguez , M. Mitjavila Casanovas , S. Ruiz Solís
{"title":"Justification and impact of SPECT ¹²³I-FP-CIT use in the differential diagnosis and management of movement disorders (MD) in a national referral hospital","authors":"L. Canales Rodríguez , M. Mitjavila Casanovas , S. Ruiz Solís","doi":"10.1016/j.remnie.2025.500092","DOIUrl":"10.1016/j.remnie.2025.500092","url":null,"abstract":"<div><div><sup>123</sup>I-FP-CIT SPECT is a key tool in the differential diagnosis of movement disorders (MD), but its appropriate indication is essential to optimize resources and avoid unnecessary tests.</div></div><div><h3>Aim</h3><div>To evaluate the adequacy and impact of <sup>123</sup>I-FP-CIT SPECT in the diagnosis and management of MD according to clinical guidelines.</div></div><div><h3>Patients and methods</h3><div>Retrospective study involving 249 patients with suspected parkinsonism (PK) of uncertain origin. All underwent <sup>123</sup>I-FP-CIT SPECT and had a clinical follow-up of exceeding 12 months. Requests were classified based on their adherence to clinical guidelines. Variables analyzed included sex, age, justification for the request, management after SPECT, and final diagnosis.</div></div><div><h3>Results</h3><div>91.57% of the requests were appropriate, while 8.43% did not adhere to the guidelines. Diagnosis changed in 48.6% of cases and management in 70.68% after the scan, especially in inconclusive cases and initiation of therapy. General neurologists evaluated more cases and made more appropriate requests (96.3% vs 76.67%; p<!--> <!--><<!--> <!-->0.001). However, MD specialists, despite less appropriate use of the guidelines, achieved a higher number of conclusive diagnoses in complex cases.</div></div><div><h3>Conclusion</h3><div><sup>123</sup>I-FP-CIT SPECT has significant clinical impact when used in accordance with clinical guidelines, improving the diagnosis and management of MD. Unjustified scans reduce its utility. Collaboration between general neurologists and MD specialists is fundamental; the latter, although showing less adherence to guidelines in requesting the test, achieve a higher number of conclusive diagnoses in complex cases.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500092"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sun-pyo Hong , Sang Mi Lee , Ik Dong Yoo , In Young Jo , Yong Kyun Won , Min-Su Kim , Hye Jeong Choi , Jeong Won Lee , Su Jin Jang
{"title":"Prognostic significance of normalized distance from maximum standardized uptake value to tumor centroid on [18F]FDG PET/CT in head and neck squamous cell carcinoma","authors":"Sun-pyo Hong , Sang Mi Lee , Ik Dong Yoo , In Young Jo , Yong Kyun Won , Min-Su Kim , Hye Jeong Choi , Jeong Won Lee , Su Jin Jang","doi":"10.1016/j.remnie.2025.500103","DOIUrl":"10.1016/j.remnie.2025.500103","url":null,"abstract":"<div><h3>Objective</h3><div>The maximum [<sup>18</sup>F]FDG uptake of a cancer lesion has been found to relocate from the center to the periphery during progression. This behavior suggests that the normalized distances from the hotspot of radiotracer uptake to the tumor centroid (NHOC) and to the tumor perimeter (NHOP) could serve as novel geometric PET parameters indicative of tumor aggressiveness. This study aimed to explore the prognostic relevance of NHOC and NHOP in [<sup>18</sup>F]FDG PET/CT for predicting the response to concurrent chemoradiotherapy (CCRT) and progression-free survival (PFS) in patients with head and neck squamous cell carcinoma (HNSCC).</div></div><div><h3>Materials and Methods</h3><div>We retrospectively reviewed 116 HNSCC patients who received CCRT and were assessed with pre-treatment (PET1) and three months post-treatment PET/CT (PET2). Along with conventional PET parameters, NHOC and NHOP for primary tumors on PET1 and the percent changes in NHOC and NHOP between PET1 and PET2 were measured.</div></div><div><h3>Results</h3><div>Of all the PET1 parameters assessed, NHOC was the most effective in predicting the CCRT response, achieving an area under the receiver operating characteristic curve of 0.645. In multivariate logistic regression and survival analysis, NHOC identified as an independent predictor for both complete metabolic response (<em>P</em> = .028) and PFS (<em>P</em> = .006). In a subgroup of 46 patients exhibiting residual primary tumors on PET2, both the percent changes in NHOC (<em>P</em> = .048) and NHOP (<em>P</em> = .041) were significantly associated with PFS.</div></div><div><h3>Conclusions</h3><div>NHOC and the percent changes in NHOC and NHOP following CCRT may serve as effective [<sup>18</sup>F]FDG PET/CT parameters for predicting clinical outcomes in HNSCC patients.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500103"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143375021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pablo Zaragoza-Ballester , Pilar Sarandeses Fernández , Inmaculada González Martín , Cristina Martin-Arriscado Arroba , María Isabel Cabanillas Pérez , Ximena Guarnizo Poma , Isabel Castel de Lucas , Álvaro Galiana Morón , Diana Vega Pérez , Ana Isabel Romero Reina , María José Tabuenca Mateo , Sebastián Ruiz Solís
{"title":"A hypoallergenic solid meal for gastric emptying scintigraphy based on mediterranean diet. “One diet to empty almost everyone”","authors":"Pablo Zaragoza-Ballester , Pilar Sarandeses Fernández , Inmaculada González Martín , Cristina Martin-Arriscado Arroba , María Isabel Cabanillas Pérez , Ximena Guarnizo Poma , Isabel Castel de Lucas , Álvaro Galiana Morón , Diana Vega Pérez , Ana Isabel Romero Reina , María José Tabuenca Mateo , Sebastián Ruiz Solís","doi":"10.1016/j.remnie.2025.500093","DOIUrl":"10.1016/j.remnie.2025.500093","url":null,"abstract":"<div><h3>Aim</h3><div>We aim to establish normal values and standardize a hypoallergenic and mediterranean diet for gastric emptying scintigraphy (GES).</div></div><div><h3>Material and methods</h3><div>In a prospective cohort of healthy volunteers, we performed GES of a [<sup>99</sup>Tc]TcDTPA<sup>2</sup> labelled hypoallergenic meal (egg, potato, rice and olive oil). Anterior and posterior images were simultaneously acquired at 0, 30, 60, 110, 120, 130, 180, 230, 240 and 250 min. Cross-sectional analysis was performed between demographic data and gastric retention values. A score covariance analysis model was used to observer changes between measurements over time.</div></div><div><h3>Results</h3><div>50 participants (29 women) were included. Mean values and standard deviation (5–95th) for gastric retention percentages at 60, 120, 180, 240 min were 51.40 ± 8.63 (36.5–66.1), 21.66 ± 9.40 (6.5–38.2), 7.58 ± 5.77 (1.5–19.1) and 2.94 ± 2.08 (1–7.3), respectively. Male participants had a significative faster gastric emptying compared to women in practically all the acquisitions. Male participants and smoker participants generated a significative decrease of gastric retention values in generalized linear model (male coefficient –4.818, IC95% –7.24 to –2.39, <em>P</em>-value < .001; and smoker coefficient of –3.484, IC95% –6.29 to –0.67, <em>P</em>-value < .05).</div></div><div><h3>Conclusion</h3><div>This study standardizes and establishes normal values for GES with the first hypoallergenic solid meal based on consensus recommendations and a mediterranean diet; suitable for most patients with allergic or sensitive-conditions to other meal components.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500093"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Nur Acar Tayyar , Müge Öner Tamam , Gündüzalp Buğrahan Babacan , Mehmet Can Şahin , Halim Özçevik , Necla Gürdal , Kadir Atakır
{"title":"[18F]FDG PET/CT beyond staging: Prognostic significance of sarcopenia and adipose tissue metabolism in esophageal carcinomas","authors":"Merve Nur Acar Tayyar , Müge Öner Tamam , Gündüzalp Buğrahan Babacan , Mehmet Can Şahin , Halim Özçevik , Necla Gürdal , Kadir Atakır","doi":"10.1016/j.remnie.2024.500090","DOIUrl":"10.1016/j.remnie.2024.500090","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to investigate the relationship between PET and CT parameters and sarcopenia, adipose tissue, and tumor metabolism in esophageal carcinoma (EC) and its impact on survival in EC.</div></div><div><h3>Method</h3><div>Our study included 122 EC patients who underwent PET/CT for staging. Muscle and adipose tissue characteristics were evaluated, including lumbar (L3) and cervical (C3) muscle areas, psoas major (PM) and sternocleidomastoid muscle (SCM) parameters, and PET parameters for visceral and subcutaneous adipose tissue (SAT). Sarcopenia was determined using CT images, with a threshold for muscle tissue at the L3 vertebral level, and its impact on overall survival (OS) was investigated.</div></div><div><h3>Results</h3><div>Sarcopenia was detected in 48 patients. SULmax in the primary tumor (PT) was significantly higher in sarcopenic patients (SP). The frequency of distant metastasis was higher in SP and OS was significantly lower. In the locally advanced stage, sarcopenia status decreased survival. L3, PM, C3, and SCM muscle areas were highly correlated. Subcutaneous adipose tissue SUVmax was significantly increased in SP and those with distant metastasis. Univariate analysis identified PT SULmax, PT SUVmean, PT TLG, lymph node and distant metastasis, SAT SUVmax, and sarcopenia as poor prognostic factors, while multivariate analysis confirmed BMI, distant metastasis, PT SUVmean, PT TLG as independent predictors of OS.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that sarcopenia, linked to reduced survival, correlates with primary tumor SULmax, distant metastasis, and subcutaneous tissue PET parameters, exerting a notable impact on survival, particularly in locally advanced stages. Attenuation-corrected CT can be used instead of diagnostic CT, and sarcopenia can be diagnosed using not only L3 but also C3 slices.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500090"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.P. Suárez Fernández, S. Naranjo Sancho, M.L. Domínguez Grande, C. Vigil Díaz, N. Martín Fernández, F.M. González García
{"title":"[18F]FDG PET/TC in the diagnosis and treatment response evaluation in a patient with systemic sarcoidosis","authors":"J.P. Suárez Fernández, S. Naranjo Sancho, M.L. Domínguez Grande, C. Vigil Díaz, N. Martín Fernández, F.M. González García","doi":"10.1016/j.remnie.2025.500135","DOIUrl":"10.1016/j.remnie.2025.500135","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 4","pages":"Article 500135"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}