F. García García , N. Cassinello Fernández , J. Rodríguez Romera , R. Martí Fernández , M. Lapeña Rodríguez , R. Alfonso Ballester , R. Díaz Expósito , J. Ortega Serrano
{"title":"PET-TC [18F]F-choline and intraoperative PTH in the surgical treatment of the primary hyperparathyroidism without preoperative location","authors":"F. García García , N. Cassinello Fernández , J. Rodríguez Romera , R. Martí Fernández , M. Lapeña Rodríguez , R. Alfonso Ballester , R. Díaz Expósito , J. Ortega Serrano","doi":"10.1016/j.remnie.2024.500066","DOIUrl":"10.1016/j.remnie.2024.500066","url":null,"abstract":"<div><h3>Background and objectives</h3><div>To assess the feasibility of performing selective parathyroidectomy without intraoperative parathyroid hormone (PTHio) determination when first-line preoperative localization tests (ultrasonography and [<sup>99m</sup>Tc]Tc-MIBI) are negative and/or discordant, and second-line [<sup>18</sup>F]F-Colina PET-CT, is positive.</div></div><div><h3>Materials and methods</h3><div>Retrospective cohort study, including patients with negative or discordant ultrasound and MIBI scans and positive [<sup>18</sup>F]F-Colina PET-CT, who underwent selective parathyroidectomy between 2019 and 2022. Groups were compared based on PTHio determination. Study variables were: gender, mean age, biochemical cure assessed by PTH value (pg/mL) and corrected calcium by albumin (mg/dL) at 6 months post-surgery follow-up, and histopathological analysis.</div></div><div><h3>Results</h3><div>The final sample included 42 patients. At 6 months post-surgery, in the PTHio group (20 patients), PTH values were 64.50 pg/mL and calcium 9.30 pg/mL, with 19 adenomas and 1 hyperplasia found. In the non-PTHio group (22 patients), PTH values were 61 pg/mL and calcium 9.37 pg/mL, with 22 adenomas found. No statistically significant differences were found between both groups.</div></div><div><h3>Conclusions</h3><div>Based on the results obtained in our patient cohort, selective parathyroidectomy could be considered with negative or discordant first-line tests and positive [<sup>18</sup>F]F-Colina PET-CT, without intraoperative PTH determination.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500066"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antitumor effect of vertebroplasty in vertebral metastasis based on quantitative 18F-FDG-PET/CT analysis","authors":"L. Bian , C. Yang , S.-W. Yin , C.-F. Ni","doi":"10.1016/j.remnie.2024.500028","DOIUrl":"10.1016/j.remnie.2024.500028","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500028"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Simó , O. Persiva , L. Sánchez , J.B. Montoro , I. Sansano , A. Vázquez , F. Ascanio , C. Alemán
{"title":"Association of PET/CT and VATS findings with histology analysis in the study of pleural effusions","authors":"M. Simó , O. Persiva , L. Sánchez , J.B. Montoro , I. Sansano , A. Vázquez , F. Ascanio , C. Alemán","doi":"10.1016/j.remnie.2024.500059","DOIUrl":"10.1016/j.remnie.2024.500059","url":null,"abstract":"<div><h3>Introduction</h3><div>Histological analysis of the pleura obtained by video-assisted thoracoscopic surgery (VATS) is the best diagnostic technique in the study of neoplastic pleural effusions. This study evaluates the relationship between Positron Emission Tomography (PET)/Computed Tomography (CT) and VATS findings, the result of the first pleural biopsy, and the final diagnosis of malignancy or non-malignancy.</div></div><div><h3>Methods</h3><div>Prospective study of consecutive patients with pleural effusions undergoing PET/CT and VATS from October 2013 to December 2023. The following variables were recorded: PET/CT score (nodular pleural thickening, pleural nodules with standardized uptake value (SUV) > 7.5, lung mass or extra pleural malignancy, mammary lymph node with SUV > 4.5 and cardiomegaly); VATS data (drained volume, visceral and parietal pleural thickening, nodules or masses, septa, plaques, fluid appearance, trapped lung, and suspected diagnosis of the procedure), as well as the histological study of the first pleural biopsy (benign or malignant) and the final diagnosis of benign or malignant pleural effusion. A logistic regression study of the variables was performed.</div></div><div><h3>Results</h3><div>95.8% of the patients with PET/CT and pleuroscopy not suggestive of malignancy had non-malignant histological findings, while 93.2% of the patients with PET/CT and pleuroscopy suggestive of malignancy had malignant histological findings. PET/CT, pleuroscopy, and the result of the first pleural biopsy showed a significant association with the final diagnosis of pleural effusion.</div></div><div><h3>Conclusions</h3><div>There is a strong association between PET/CT findings, VATS and pleural histology.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500059"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. Noriega-Álvarez , B. Rodríguez Alfonso , J.J. Rosales Castillo , A. Moreno Ballesteros , E. López Rodríguez , S. Sanz Viedma , M. del P. Orduña Diez , L. Domínguez Gadea
{"title":"Role and applications of 18F-FDG PET/CT in the assessment of osteoarticular infection and inflammation — Part I","authors":"E. Noriega-Álvarez , B. Rodríguez Alfonso , J.J. Rosales Castillo , A. Moreno Ballesteros , E. López Rodríguez , S. Sanz Viedma , M. del P. Orduña Diez , L. Domínguez Gadea","doi":"10.1016/j.remnie.2024.500073","DOIUrl":"10.1016/j.remnie.2024.500073","url":null,"abstract":"<div><div><sup>18</sup>F-FDG PET/CT has been positioned over time as a useful tool in the evaluation of osteoarticular infections, overcoming conventional explorations like MRI or bone scintigraphy in some indications. Its ability to provide functional and anatomical images simultaneously and its excellent resolution contributes to a more precise and personalised approach in the treatment of osteoarticular diseases such as spondylodiscitis. In addition, it has proven valuable in patients with suspected infection that is complex to diagnose or treat, improving detection in subclinical stages. However, some limitations have been identified, such as difficulty in the differential diagnosis of infection vs. inflammation (as in diabetic foot) or in the interpretation of patients with osteosynthesis materials. In this manuscript, we present a brief review providing general and practical information about the role of <sup>18</sup>F-FDG PET/CT in infectious osteoarticular pathology, while part 2 discusses the role of <sup>18</sup>F-FDG PET/CT in osteoarticular inflammation.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500073"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Tercero Garrido , M.V. Guiote Moreno , C. Rodelo-Haad , P.I. Contreras Puertas , S. Soriano Cabrera , M.D. Albalá González
{"title":"Peritoneal scintigraphy and SPECT/TC in the diagnosis of leaks in patients on peritoneal dialysis","authors":"D. Tercero Garrido , M.V. Guiote Moreno , C. Rodelo-Haad , P.I. Contreras Puertas , S. Soriano Cabrera , M.D. Albalá González","doi":"10.1016/j.remnie.2024.500067","DOIUrl":"10.1016/j.remnie.2024.500067","url":null,"abstract":"<div><h3>Objective</h3><div>To assess the usefulness of peritoneal cavity scintigraphy and the contribution of SPECT/CT in patients on peritoneal dialysis with suspected leak.</div></div><div><h3>Methodology</h3><div>An observational case series study is carried out. It consists of a longitudinal, retrospective and descriptive study. 11 patients on peritoneal dialysis were studied and it was realiced a peritoneal cavity scintigraphy test and SPECT/CT to evaluate a peritoneal leak.</div></div><div><h3>Results</h3><div>In 54,5% of the patients, a positive study of peritoneal leak was obtained. The most frequent localitations were in the abdominal wall at the catheter entry level and the inguinal hernia. In the cases with sintomatology like pain and celullitis of the subcutaneous tract of the cateter the frequent of leak was 100%. There was a change in therapeutic management in patients with a positive study. There was not relevant changes in initial dialysis regimen in patients with a negative study. In this cases, except for one patient who required hemodialysis, all patients experienced clinical improvement.</div></div><div><h3>Conclusions</h3><div>Peritoneal scintigraphy and SPECT/CT study are non-invasive techniques that allow an adequate diagnosis and subsequent management of peritoneal leak.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500067"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Garcia Garcia , A.P. Caresia Aróztegui , S. Martínez Román
{"title":"Use of propranolol in [18F] FDG-PET/CT for differential diagnosis of brown fat in patient with a history of adenocarcinoma of the uterine cervix","authors":"A. Garcia Garcia , A.P. Caresia Aróztegui , S. Martínez Román","doi":"10.1016/j.remnie.2024.500068","DOIUrl":"10.1016/j.remnie.2024.500068","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500068"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J.J. Rosales , M.L. Domínguez , L. Sancho , E. Prieto , M. de Arcocha , I. Torres , A. Roteta , R. Ramos , G. Quincoces
{"title":"State of the art and future perspectives of new radionuclides in Nuclear Medicine","authors":"J.J. Rosales , M.L. Domínguez , L. Sancho , E. Prieto , M. de Arcocha , I. Torres , A. Roteta , R. Ramos , G. Quincoces","doi":"10.1016/j.remnie.2025.500082","DOIUrl":"10.1016/j.remnie.2025.500082","url":null,"abstract":"<div><div>This continuing education analyzes recent advances in Nuclear Medicine focused on the development of new radiopharmaceuticals that improve both the diagnosis and treatment of complex diseases. The focus is on teragnosis, which combines diagnosis and treatment by means of pairs of radiopharmaceuticals directed to the same molecular target, which allows the personalization of treatments.</div><div>This first part specifically reviews the teragnostic pairs copper-64/copper-67, lead-212/lead-203 and scandium-44/scandium-47, highlighting their physical characteristics, methods of production and potential clinical applications.</div><div>Despite the challenges in their production, their versatility and effectiveness are driving their clinical application in oncology and other diseases. The text also addresses the development of new radiopharmaceuticals and their impact on precision medicine, pointing out future directions and opportunities for research in this field.</div></div>","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500082"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Martínez-Rodríguez, F. Gómez-de la Fuente, A. Sánchez-Salmón, M. Pombo-López, A. Bota-Bota, R. Quirce
{"title":"18F-FDG PET/CT in the staging, therapeutic evaluation and follow-up of prostatic sarcoma","authors":"I. Martínez-Rodríguez, F. Gómez-de la Fuente, A. Sánchez-Salmón, M. Pombo-López, A. Bota-Bota, R. Quirce","doi":"10.1016/j.remnie.2024.500039","DOIUrl":"10.1016/j.remnie.2024.500039","url":null,"abstract":"","PeriodicalId":94197,"journal":{"name":"Revista espanola de medicina nuclear e imagen molecular","volume":"44 1","pages":"Article 500039"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142515630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}