Revista da Associacao Medica Brasileira (1992)最新文献

{"title":"Liver/spleen magnetic resonance elastography and T1/T2 mapping in chronic liver disease: a prospective study.","authors":"Gökhan Mert Özyurt, Kaan Esen, Enver Üçbilek, Feramuz Demir Apaydın","doi":"10.1590/1806-9282.20241008","DOIUrl":"10.1590/1806-9282.20241008","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to compare liver and spleen stiffness measurements using magnetic resonance elastography with T1 and T2 relaxation times in patients with chronic liver disease.</p><p><strong>Methods: </strong>A total of 75 chronic liver disease patients and 25 healthy volunteers underwent MR. Patients with significant liver fat and iron accumulation were excluded. Student's t-test was employed to compare magnetic resonance elastography and T1/T2 values. Pearson's correlation test was used to assess the relationship between magnetic resonance elastography and T1/T2 values.</p><p><strong>Results: </strong>Liver magnetic resonance elastography showed a significant moderate positive correlation with liver T1 mapping (r=0.51, p<0.001) and liver T2 mapping (r=0.30, p=0.009) in patients. Spleen magnetic resonance elastography exhibited a significant moderate positive correlation with spleen T2 mapping (r=0.37, p=0.001). However, there was no significant correlation between spleen magnetic resonance elastography and spleen T1 mapping in patients. Spleen magnetic resonance elastography was moderately positively correlated with liver magnetic resonance elastography (r=0.30, p=0.01), and spleen volume showed positive correlations with spleen magnetic resonance elastography, spleen T1 mapping, and spleen T2 mapping. Cut-off values for liver magnetic resonance elastography, liver T1 mapping, and liver T2 mapping in patient and control groups were 2.6 kPa (AUC=0.97), 619 ms (AUC=0.90), and 52.5 ms (AUC=0.62), respectively.</p><p><strong>Conclusion: </strong>Relaxation methods offer noninvasive imaging without additional equipment. Liver T1 mapping may serve as an alternative to magnetic resonance elastography for chronic liver patient follow-up, while spleen T1 mapping is not reliable.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20241008"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women with pelvic organ prolapse and fibulin-5 rs12589592 polymorphism.","authors":"Fabiana Garcia Reis Maeda, Claudia Cristina Palos, Cesar Eduardo Fernandes, Ricardo Peres do Souto, Emerson de Oliveira","doi":"10.1590/1806-9282.20240687","DOIUrl":"10.1590/1806-9282.20240687","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to access the frequency of single-nucleotide polymorphism rs12589592 (G>A) of the fibulin-5 gene in a Brazilian population with pelvic organ prolapse.</p><p><strong>Methods: </strong>This was a case-control study, with menopausal women divided into two groups and classified using the pelvic organ prolapse quantification system: pelvic organ prolapse group: pelvic organ prolapse quantification system stages III and IV and Control group: pelvic organ prolapse quantification system stages I and 0. We collected epidemiologic and baseline health information and performed genotyping of rs12589592 from the fibulin-5 gene using a restriction fragment length polymorphism (polymerase chain reaction-restriction fragment length polymorphism) strategy, based on the distinction of sequences from alleles G and A by the restriction enzyme DdeI. For the pelvic organ prolapse group and control, 111 and 180 women were recruited, respectively.</p><p><strong>Results: </strong>The rs12589592 (G>A) polymorphism analysis showed 141 GG homozygotes (pelvic organ prolapse group: 53 [47.7%] and Control: 88 [49.2%] p=0.850); and 149 AA+GA: (pelvic organ prolapse group: 58 [52.3%]; Control: 91 [50.8%]; p=0.904). The distribution of genotypes did not follow the Hardy-Weinberg equilibrium conditions.</p><p><strong>Conclusion: </strong>There was no difference between groups regarding genotypes (rs12589592 G>A) frequency; however, the population characteristics prevent the analysis of the association between the genotype and the occurrence of prolapse.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 11","pages":"e20240687"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum.","authors":"","doi":"10.1590/1806-9282.20240680ERRATUM","DOIUrl":"10.1590/1806-9282.20240680ERRATUM","url":null,"abstract":"<p><p>[This corrects the article doi: 10.1590/1806-9282.20240680].</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 11","pages":"e20240680ERRATUM"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"The effect of preoperative embolization rate on surgical outcomes for carotid paraganglioma resection\".","authors":"Abdullah Güner, Muhammet Hüseyin Erkan","doi":"10.1590/1806-9282.20241387","DOIUrl":"10.1590/1806-9282.20241387","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20241387"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The predictive ability of Controlling Nutritional Status score on in-hospital mortality in patients admitted to coronary care unit.","authors":"Serdar Gökhan Nurkoç, Şeyhmus Atan, Mehmet Koray Adalı, Mevlüt Demir, Yunus Emre Yavuz, Burak Açar, Meltem Altınsoy, İbrahim Halil Tanboğa, Fatih Kahraman","doi":"10.1590/1806-9282.20240958","DOIUrl":"10.1590/1806-9282.20240958","url":null,"abstract":"<p><strong>Objective: </strong>Controlling Nutritional Status score was previously described and has been used in predicting short- and long-term outcomes in different patient populations. The aim of this study was to test the relationship between Controlling Nutritional Status score and in-hospital mortality in coronary care unit patients (MORCOR-TURK population).</p><p><strong>Methods: </strong>In this multicenter and national study, all patients with an available Controlling Nutritional Status score were included in the analysis. The Controlling Nutritional Status score was calculated according to previously described criteria. To be able to understand the significance of the Controlling Nutritional Status score, we constructed two models. Model 1 included age, heart failure, chronic kidney disease, hypertension, diabetes mellitus, and coronary artery disease history. Model 2 included the Controlling Nutritional Status score and Model 1. We then statistically compared the performances of the two models.</p><p><strong>Results: </strong>A total of 1,018 patients with known Controlling Nutritional Status scores were included in the analysis. Demographic characteristics are shown. In Model 1, the -2 log-likelihood ratio was 395.995, Nagelkerke R2 was 0.133, and area under the curve was 0.739 (95%CI 0.67-0.81). In the second model to which the Controlling Nutritional Status score is added (Model 2), the -2 log-likelihood ratio was 373.743, Nagelkerke R2 was 0.191, and area under the curve was 0.787 (95%CI 0.72-0.85). The area under the curve value of Model 2 was statistically higher than Model 1 (DeLong p-value: 0.01). A statistically significant correlation was found between death and Controlling Nutritional Status score in Model 2 [OR 1.347 (1.193-1.521), p<0.001].</p><p><strong>Conclusions: </strong>Our study showed that the Controlling Nutritional Status score may be a significant predictor of in-hospital mortality in coronary care unit patients.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20240958"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Genetic variants in miR-146a and miR-196a2 in endometriosis: a Brazilian study\".","authors":"Chunfeng Guo, Xiaoyan Liu","doi":"10.1590/1806-9282.20241085","DOIUrl":"10.1590/1806-9282.20241085","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 11","pages":"e20241085"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142781657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Ozaki procedure on hematological and biochemical parameters.","authors":"Yasin Ozden, Ferdi Peynirci, Seyma Ozden, Mutlu Senocak, Yavuz Sensoz, Ilyas Kayacioglu","doi":"10.1590/1806-9282.20240944","DOIUrl":"10.1590/1806-9282.20240944","url":null,"abstract":"<p><strong>Introduction: </strong>The Ozaki procedure is an open-heart surgery technique used in aortic valve surgery. We investigated the effect of the Ozaki procedure on postoperative hematological and biochemical parameters as in other open-heart surgery applications.</p><p><strong>Methods: </strong>A total of 42 patients between December 2020 and December 2022 who underwent the Ozaki procedure were analyzed retrospectively. Patients without any comorbid cardiac pathology were included in the study. Preoperative 3rd day, postoperative 6th hour, postoperative 24th hour, postoperative 7th day, and postoperative 30th day hematological and biochemical parameters of 42 patients with screening results were examined.</p><p><strong>Results: </strong>Postoperative values were compared according to preoperative values. According to this, hematocrit and hemoglobin values were significantly lower at all times postoperatively. While white blood cells were found to be significantly higher until the postoperative 7th day, platelets were found to be significantly lower. The highest levels of creatine, blood urea, nitrogen, and aspartate aminotransferase were detected at the postoperative 24th hour, while the highest level for alanine aminotransferase was observed at the postoperative 7th day.</p><p><strong>Conclusion: </strong>As with all open-heart surgery methods, the Ozaki procedure may cause some changes in hematological and biochemical parameters in the postoperative period. So, this situation is the same as in other open-heart surgery methods.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20240944"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic obliquity, trunk control, and motor function: an exploratory study in a non-ambulatory Duchenne muscular dystrophy cohort.","authors":"Fatma Uğur, İpek Gürbüz, Özlem Yayıcı Köken, Ayşegül Neşe Çıtak Kurt, Öznur Yılmaz","doi":"10.1590/1806-9282.20241109","DOIUrl":"10.1590/1806-9282.20241109","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the relationship between pelvic obliquity and trunk control, spinal deformity, upper extremity functional performance, and motor function in patients with non-ambulatory Duchenne muscular dystrophy.</p><p><strong>Methods: </strong>This cross-sectional study included 21 patients with Duchenne muscular dystrophy aged 8-18 years. In the study, participants' upper extremity functional levels, pelvic obliquity degrees, spinal deformity, trunk control, upper extremity performance, and motor functions were evaluated using various tools such as the Brooke Upper Extremity Functional Scale, baseline scoliometer, spinal mouse, Trunk Control Measurement Scale, Upper Extremity Performance Scale, and Egen Klassifikation Scale Version 2, respectively.</p><p><strong>Results: </strong>The study found a strong correlation between pelvic obliquity and frontal spine deformity (p<0.01), as well as moderate relationships between pelvic obliquity, motor function, wheelchair usage duration, and knee flexion contractures (p<0.05).</p><p><strong>Conclusion: </strong>The study found that pelvic obliquity may lead to spinal health deterioration and motor function limitations in non-ambulatory patients with Duchenne muscular dystrophy, especially those with lower extremity joint contractures and long-term wheelchair use.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20241109"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of subclavian vein and inferior vena cava collapsibility index in the intensive care unit.","authors":"Serkan Solak, Suheyla Karadag Erkoç, Onat Ahmet Bermede, Mustafa Kemal Bayar","doi":"10.1590/1806-9282.20240786","DOIUrl":"10.1590/1806-9282.20240786","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the correlation between changes in the inferior vena cava collapsibility index and subclavian vein collapsibility index in patients undergoing passive leg raising tests in the intensive care unit, considering that respiratory changes affecting the inferior vena cava may similarly affect the subclavian vein.</p><p><strong>Methods: </strong>This single-center observational study was conducted on patients aged between 18 and 85 years who underwent passive leg raising in the intensive care unit. When the patient was 45° above the bed, the inferior vena cava and subclavian vein were displayed using ultrasonography; subclavian vein collapsibility index and inferior vena cava collapsibility index values were calculated. After the initial values were recorded, passive leg raising was performed, and the initial measurements were repeated. The CI values measured after passive leg raising were subtracted from those calculated before passive leg raising to determine the changes (Δ) in inferior vena cava and subclavian vein collapsibility indices.</p><p><strong>Results: </strong>The study was conducted with a total of 64 patients. The mean±standard deviation values for ΔIVC-CI% and ΔSCV-CI% variables were found as 8.97±8.89 and 10.31±10.81, respectively. There were no statistically significant differences in values of ΔIVC-CI% and ΔSCV-CI% (p=0.297). In the Bland-Altman plot, because there were only two values exceeding the +1.96 SD and -1.96 SD limits, it can be said that the agreement between ΔIVC-CI% and ΔSCV-CI% was adequate.</p><p><strong>Conclusion: </strong>ΔSCV-CI% values are compatible and correlated with ΔIVC-CI% values. Inferior vena cava and subclavian vein responded similarly to fluid changes during passive leg raising.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20240786"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of breathing exercises on fatigue in tuberculosis patients: a randomized controlled trial.","authors":"Sema Aytaç, Özlem Ovayolu, Sibel Dogru","doi":"10.1590/1806-9282.20240888","DOIUrl":"10.1590/1806-9282.20240888","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted as a randomized controlled trial to investigate the effect of breathing exercises on fatigue in patients diagnosed with tuberculosis.</p><p><strong>Methods: </strong>The tuberculosis patients included in the study were divided into two groups: intervention (26) and control (28) by a program established after the power analysis. After the researcher informed the patients in the intervention group about breathing exercises, including diaphragmatic and pursed lip breathing, they were taught, and the first exercise was practiced. Then, the patients in this group did breathing exercises once a day in the morning, 3 days a week, for a total of 4 weeks, with the researcher using the online interview method. The data were collected using a questionnaire and the Piper Fatigue Scale. The total score of the Piper Fatigue Scale ranges from 0 to 10, and the higher the score, the higher the fatigue level. The Piper Fatigue Scale was repeated at the end of the fourth week in both groups.</p><p><strong>Results: </strong>Patients in the intervention group (88.5%) and control group (85.7%) reported that they were tired after the diagnosis of tuberculosis. The Piper Fatigue Scale total mean score of the intervention group was 8.29±1.19 before the intervention and dropped to 6.83±1.02 at the fourth week (p<0.05), whereas the Piper Fatigue Scale total mean score of the control group was 7.88±1.09 before the intervention and 7.93±1.02 at the fourth week (p>0.05).</p><p><strong>Conclusion: </strong>Breathing exercises done by tuberculosis patients were found to lower their levels of fatigue. Accordingly, it is recommended to benefit from breathing exercises, which are effective, inexpensive, and easy to apply in the management of fatigue.</p><p><strong>Clinical trial registration number: </strong>The study was registered with clinicaltrial.gov NCT05202431.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"70 12","pages":"e20240888"},"PeriodicalIF":0.0,"publicationDate":"2024-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11639563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}