Revista da Associacao Medica Brasileira (1992)最新文献

{"title":"Critical methodological review of 1-year survival outcomes in the intensive care unit.","authors":"Ömerul Faruk Aydın","doi":"10.1590/1806-9282.20241504","DOIUrl":"10.1590/1806-9282.20241504","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241504"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between risky sexual behaviors and sexual health literacy and self-esteem in young women.","authors":"Sevil Cicek Ozdemir, Esra Cevik","doi":"10.1590/1806-9282.20241040","DOIUrl":"10.1590/1806-9282.20241040","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this research was to examine the relationship between risky sexual behaviors and sexual health literacy and self-esteem in young women.</p><p><strong>Methods: </strong>The research is descriptive and cross-sectional type. In total, 705 young women were included in the research. The study data were collected online using an online survey system through Google Forms. The data were collected between April and July 2023.</p><p><strong>Results: </strong>The factors affecting premarital risky sexual behavior were determined to be the educational level of the woman and her mother, where the women lived the longest, current residence, family status, father's educational level, employment status of the woman and her mother, and smoking and alcohol use status. Using alcohol (13 times), smoking (4 times), and mother's employment status (3 times) have the highest effect on the mean Premarital Sexual Behavior Assessment Scale for Young Women score. There is a significant negative correlation between Premarital Sexual Behavior Assessment Scale for Young Women and Sexual Health Literacy Scale. There is no significant relationship between Premarital Sexual Behavior Assessment Scale for Young Women and Rosenberg Self-Esteem Scale.</p><p><strong>Conclusion: </strong>Increasing sexual health literacy levels, quitting smoking and alcohol, and engaging in self-esteem-enhancing activities in women are essential for reducing risky sexual behaviors.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241040"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breast cancer radiotherapy: analysis of unintended internal mammary node doses and influencing factors.","authors":"Fevziye İlknur Kayalı, Rahşan Habiboğlu, İpek Pınar Aral, Volkan Çevik, Yılmaz Tezcan","doi":"10.1590/1806-9282.20241325","DOIUrl":"10.1590/1806-9282.20241325","url":null,"abstract":"<p><strong>Objective: </strong>Breast cancer is a prevalent malignancy requiring ongoing treatment advancements. Radiotherapy is vital for reducing recurrence and improving survival. This study evaluates unintended doses to internal mammary lymph nodes and influencing factors in patients at Ankara Bilkent City Hospital's Radiation Oncology Clinic.</p><p><strong>Methods: </strong>We analyzed 44 right-sided breast cancer patients treated with radiotherapy between November 2019 and April 2023. Data on demographics, treatment, and dose-volume histograms were reviewed using various statistical tests.</p><p><strong>Results: </strong>Median age was 54 years; 88.6% had invasive ductal carcinoma, and 11.4% had ductal carcinoma in situ. Patients received conventional (54.5%) or hypofractionated radiotherapy (45.5%) using intensity-modulated radiotherapy or three-dimensional conformal radiotherapy. Median internal mammary lymph node volume was 7.3 cc with dose variability. Internal mammary lymph nodes V45 dose showed no correlation with internal mammary lymph nodes volume, radiotherapy field, pT stage, or pN stage. However, the nodal stage significantly impacted the internal mammary lymph nodes D95 dose, with higher doses in N1 patients. Wider radiotherapy fields led to increased D95 doses.</p><p><strong>Discussion: </strong>The findings highlight the variability in internal mammary lymph nodes doses and the impact of nodal stage and radiotherapy field on dose distribution. Advanced techniques like intensity-modulated radiotherapy can reduce risks, but careful planning is essential.</p><p><strong>Conclusion: </strong>Understanding internal mammary lymph nodes dose factors can enhance treatment planning and outcomes. Future research should focus on refining guidelines and leveraging technology to improve radiotherapy efficacy.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241325"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is the presence of a catheter and time of surgery effective in conversion to open surgery in interval cholecystectomies after percutaneous drainage in acute cholecystitis?","authors":"Gökhan Demiral, Ali Özdemir, Süleyman Kalcan, Hasan Gündoğdu, Ahmet Pergel","doi":"10.1590/1806-9282.20241051","DOIUrl":"10.1590/1806-9282.20241051","url":null,"abstract":"<p><strong>Objective: </strong>There are no guidelines regarding intraoperative or preoperative catheter removal in patients eligible for surgery following percutaneous drainage in acute cholecystitis. In this study, we evaluated the factors affecting the conversion to open surgery after percutaneous drainage and analyzed the relationship between catheter presence and time to operation in interval laparoscopic cholecystectomy.</p><p><strong>Methods: </strong>In total, 50 patients with acute cholecystitis who underwent interval laparoscopic cholecystectomy after percutaneous drainage were retrospectively evaluated and grouped according to conversion to open surgery (Group 1) and non (Group 2). Factors that may be associated with conversion to open surgery and the presence of an intraoperative catheter were evaluated, and the time to surgery was calculated.</p><p><strong>Results: </strong>There were 28 (56%) men and 22 (44%) women, and the mean age was 64 (±13) years. The severity of acute cholecystitis was moderate in 37 (74%) patients and severe in 13 (26%). When the groups were compared, no statistically significant difference was found between the presence of a catheter, the time of surgery 8 weeks before and after, and the conversion to open surgery. Postoperative hospitalization days were significantly higher in Group 1 (p=0.014).</p><p><strong>Conclusion: </strong>In patients who underwent interval laparoscopic cholecystectomy after insertion of a percutaneous drainage catheter in acute cholecystitis, the presence of a catheter and the waiting time for surgery after catheter insertion do not affect the rates of conversion to open surgery and complications.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241051"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between cancer information burden, attitudes, and behaviors toward cancer screenings in women aged 30-70 years.","authors":"Tuğba Solmaz, Aygül Kıssal","doi":"10.1590/1806-9282.20241395","DOIUrl":"10.1590/1806-9282.20241395","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the relationship between cancer information burden, attitudes, and behaviors toward cancer screening in women aged 30-70 years who applied to family health centers.</p><p><strong>Methods: </strong>The data were collected with Personal Information Form, Attitude Scale for Cancer Screening, and Cancer Information Overload Scale from 398 women.</p><p><strong>Results: </strong>The mean score of the participants was 16.22±4.66 on the Cancer Information Overload Scale and 93.05±13.80 on the Attitude Scale for Cancer Screening. A statistically significant difference was found between the mean scores of the women according to their educational level, occupational status, knowledge about cancer screening, and the presence of cancer in themselves or their families (p<0.05). In addition, a strong positive but statistically insignificant correlation (r=0.061, p=0.223) was found between the Cancer Information Overload Scale and the scores of the Attitude Scale for Cancer Screening.</p><p><strong>Conclusion: </strong>Women had low rates of knowing the timing of colon, cervical, and breast cancer screenings, having been screened, and thinking of participating in screenings in the following year. In order to improve women's attitudes toward early diagnosis of cancer in a positive way, informative public education activities should be continued.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241395"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The relationship between the timing of pregnancy discovery and prenatal attachment and distress: a case-control study.","authors":"Yasemin Sökmen, Şükran Başgöl","doi":"10.1590/1806-9282.20241399","DOIUrl":"10.1590/1806-9282.20241399","url":null,"abstract":"<p><strong>Objective: </strong>This research was conducted to determine the relationship between the timing of pregnancy discovery and prenatal attachment and distress.</p><p><strong>Methods: </strong>An analytical, case-control research design was used. The study was conducted between April 2023 and March 2024. The population of the study consisted of pregnant women who presented to a training and research hospital in the north of Turkey for antenatal follow-up, and the sample consisted of 152 women from this population (case group 76 and control group 76). Data were collected using a Pregnant Descriptive Information Form, the Prenatal Attachment Inventory, and the Prenatal Distress Scale-Revised Version. The chi-square test, Mann-Whitney U test, and Spearman correlation analysis were utilized to analyze the data.</p><p><strong>Results: </strong>The prenatal attachment scores of participants who discovered their pregnancies late were significantly lower than the scores of those whose pregnancies were discovered early (p<0.05). The prenatal distress scores of participants whose pregnancies were discovered late were significantly higher than the scores of those with early discovery (p<0.05). While a statistically positive, low-level relationship was detected between the prenatal attachment and prenatal distress scores of pregnant women whose pregnancies were discovered early (p<0.05), there was no statistically significant relationship between the scores of those who discovered their pregnancies late (p>0.05).</p><p><strong>Conclusion: </strong>There was a difference between the timing of pregnancy discovery and prenatal attachment and prenatal distress.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241399"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the cardiac impacts of endothelial PAS domain-containing protein 1 and ghrelin in patients with systemic lupus erythematosus.","authors":"Yakup Alsancak, Ahmet Taha Sahin, Oznur Keskin, Selman Parlak","doi":"10.1590/1806-9282.20241412","DOIUrl":"10.1590/1806-9282.20241412","url":null,"abstract":"<p><strong>Objective: </strong>Systemic lupus erythematosus is a chronic autoimmune disease with significant cardiac manifestations, including right ventricular dysfunction and pulmonary hypertension. This study aims to explore the relationship between endothelial PAS domain-containing protein 1 and ghrelin levels with right ventricular function in patients with systemic lupus erythematosus and assess their potential as biomarkers for cardiac involvement.</p><p><strong>Methods: </strong>A prospective study was conducted involving 34 patients with systemic lupus erythematosus and 35 healthy controls. Echocardiographic parameters were recorded. Serum levels of endothelial PAS domain-containing protein 1 and ghrelin were measured using enzyme-linked immunosorbent assay. Statistical analyses included comparisons between groups and correlations between biomarkers and echocardiographic parameters.</p><p><strong>Results: </strong>Patients with systemic lupus erythematosus had significantly higher levels of endothelial PAS domain-containing protein 1 and ghrelin compared with healthy controls (p<0.001). Endothelial PAS domain-containing protein 1 showed a moderate positive correlation with right ventricular systolic motion (p=0.007). Patients with systemic lupus erythematosus and a higher disease activity had elevated endothelial PAS domain-containing protein 1 levels, particularly those with positive antiphospholipid antibodies (p<0.001). No significant correlation was found between ghrelin levels and right ventricular function. Receiver operating characteristic curve analysis identified cutoff values for endothelial PAS domain-containing protein 1 (≥1.871) and ghrelin (≥360.50) with moderate sensitivity and specificity for predicting systemic lupus erythematosus.</p><p><strong>Conclusion: </strong>This study suggests that endothelial PAS domain-containing protein 1 and ghrelin may play important roles in the pathophysiology of right ventricular dysfunction in systemic lupus erythematosus.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241412"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trend in venous thromboembolism hospitalization rates in Brazil.","authors":"Felipe Soares Oliveira Portela, Nelson Wolosker, Andressa Cristina Sposato Louzada, Maria Fernanda Cassino Portugal, Marcelo Fiorelli Alexandrino da Silva, Diogo Lopes Cintra, Giulia de Payrebrune St Sève Marins Girardi, Alexandre Fioranelli, Marcelo Passos Teivelis","doi":"10.1590/1806-9282.20240608","DOIUrl":"10.1590/1806-9282.20240608","url":null,"abstract":"<p><strong>Objective: </strong>Venous thromboembolism is a condition of great interest to public health, as it is potentially preventable and has a high morbidity and mortality potential. Knowing the real-world data in a country of continental dimensions such as Brazil is essential to help define health policies that enable proper diagnosis and treatment of this disease. The objective of this study was to evaluate the incidence and in-hospital mortality rates of venous thromboembolism in public hospitals under Brazil's public health system.</p><p><strong>Methods: </strong>This is a population-based, cross-sectional, retrospective analysis of all hospitalizations for venous thromboembolism in the Brazilian public health system between 2008 and 2022. Using a public database, all hospital admissions for thromboembolic events were selected, defining the incidence, in-hospital mortality, and differences between Brazilian macro-regions.</p><p><strong>Results: </strong>A total of 700,315 admissions for venous thromboembolism were documented in the Brazilian public health system between 2008 and 2022, which represents 3.02 admissions per 10,000 inhabitants per year. The Southeast region accounted for more than half (54.5%) of the hospitalizations. The highest incidence of hospitalizations occurred in the wealthiest regions (Southeast and South), while the lowest incidence was observed in the poorest regions (North and Northeast). On the other hand, a higher proportion of in-hospital mortality was observed in the North and Northeast regions.</p><p><strong>Conclusion: </strong>The highest admission rates were registered in wealthier regions, while a higher proportion of deaths was found in the poorer ones. This may reveal the difficulty in accessing healthcare services in the North and Northeast regions, which is reflected in the potential underdiagnosis of thromboembolic events in these regions.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20240608"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Oncovascular surgery\".","authors":"Veronica Maggi, Simone Garzon, Massimo Piergiuseppe Franchi, Gian Franco Veraldi, Stefano Uccella","doi":"10.1590/1806-9282.20241479","DOIUrl":"10.1590/1806-9282.20241479","url":null,"abstract":"","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241479"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964307/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presepsin is a biomarker that can predict mortality in sepsis patients.","authors":"Naim Uzun, Adem Keskin, Recai Aci, Melek Bilgin, Sunay Akgun","doi":"10.1590/1806-9282.20241262","DOIUrl":"10.1590/1806-9282.20241262","url":null,"abstract":"<p><strong>Objective: </strong>Predicting the prognosis of sepsis, a major health problem worldwide, is vital to guide the treatment process accordingly. The aim of this study was to evaluate the ability of presepsin levels to predict mortality in patients with sepsis.</p><p><strong>Methods: </strong>The study included 87 intensive care unit patients with sepsis, 30 of whom survived. Complete blood count, blood gas, C-reactive protein, procalcitonin, albumin, and presepsin levels were analyzed. Binary logistic regression and receiver operating characteristic analyses were performed for presepsin levels.</p><p><strong>Results: </strong>Presepsin levels were higher in non-survivors than in survivors. There was no significant difference in other laboratory parameters. The predictive value of presepsin level on mortality was found to be 78.20%. The cutoff value in the receiver operating characteristic curve graph for presepsin levels is 612.70 pg/mL. The positive predictive value of presepsin levels in terms of mortality is 0.5735, and the negative predictive value is 0.8512. The sensitivity of presepsin levels in terms of mortality is 73.70%, and the specificity is 73.30%. The area under the curve value in the receiver operating characteristic curve plot for mortality for presepsin levels is 0.819.</p><p><strong>Conclusion: </strong>Presepsin levels may predict mortality in patients with sepsis. Presepsin levels above the cutoff value of 612.70 pg/mL may be considered a risk factor for mortality in patients with sepsis.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 2","pages":"e20241262"},"PeriodicalIF":0.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11964312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}