{"title":"Early detection and treatment of cardiac dysfunction in cancer patients improve overall survival.","authors":"Lin Zheng, Jiawu Weng, Mingming Zhang","doi":"10.1590/1806-9282.20241437","DOIUrl":"https://doi.org/10.1590/1806-9282.20241437","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study was to analyze the impact of the early detection and treatment of cardiac dysfunction on overall survival in cancer patients.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on clinical data from 60 cancer patients with concurrent cardiac dysfunction, admitted between January 2020 and November 2022. Patients were divided into an early treatment group (n=35), where treatment began within 24 h of diagnosis, and a late treatment group (n=25), where treatment started after 24 h. The clinical efficacy, early diastolic filling velocity, fractional shortening, left ventricular ejection fraction, and Quality of Life Questionnaire-Core 30 scores were compared before and after treatment. Adverse reactions, cardiovascular events, and 1-year survival rates were also evaluated.</p><p><strong>Results: </strong>The early treatment group showed higher total effective and survival rates compared to the late group (p<0.05). The post-treatment levels of early diastolic filling velocity, fractional shortening, left ventricular ejection fraction, and Quality of Life Questionnaire-Core 30 scores were statistically significantly higher in the early group (p<0.05), with no notable differences in adverse reactions (p>0.05). Kaplan-Meier analysis revealed a statistically significantly higher 1-year survival probability in the early treatment group (log-rank p=0.02).</p><p><strong>Conclusion: </strong>Early detection and treatment of cardiac dysfunction in cancer patients can improve treatment efficacy and survival rate, better improve cardiac function and quality of life, and reduce the occurrence of adverse cardiovascular events.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241437"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mahmut Padak, Reşat Dikme, Ezhar Ersöz, Yasemin Hacanlı
{"title":"Comparison of the effect of cardioplegic solutions used in cardiac surgery on myocardial protection.","authors":"Mahmut Padak, Reşat Dikme, Ezhar Ersöz, Yasemin Hacanlı","doi":"10.1590/1806-9282.20241451","DOIUrl":"https://doi.org/10.1590/1806-9282.20241451","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this retrospective study was to evaluate the effects of cardioplegic solutions on myocardial protection factors in patients undergoing cardiac surgery with cardiopulmonary bypass and to evaluate the relationship between these effects and early clinical outcomes.</p><p><strong>Methods: </strong>A total of 78 patients were included in the study. The data of patients who received del Nido cardioplegia (Group 1; n=39) and blood cardioplegia (Group 2; n=39) during the operation were grouped and compared. Preoperative and postoperative routine parameters such as creatine phosphokinase, troponin I, C-reactive protein, and demographic data were recorded, and statistical analyses were performed.</p><p><strong>Results: </strong>Perfusion time, cross-clamp time, act pump, preoperative C-reactive protein, preoperative creatine phosphokinase, preoperative troponin I, postoperative C-reactive protein, postoperative creatine phosphokinase, postoperative troponin I values were significantly different between del Nido and blood groups (p<0.05).</p><p><strong>Conclusion: </strong>Del Nido cardioplegia provided myocardial protection and early postoperative favorable results compared to blood cardioplegia, which may make it a viable option for conventional cardiopulmonary bypass.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241451"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051972/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of adulthood immunization knowledge, attitudes, and behavior.","authors":"Özgür Özerdoğan, Sibel Oymak, Coşkun Bakar","doi":"10.1590/1806-9282.20241779","DOIUrl":"https://doi.org/10.1590/1806-9282.20241779","url":null,"abstract":"<p><strong>Objective: </strong>Adulthood vaccination has not reached adequate levels, both in Turkey and around the world. The aim of this study was to identify the knowledge, attitude, and behavior of vaccination in those aged 18 years.</p><p><strong>Methods: </strong>This is a cross-sectional study. Questionnaires were applied to 686 participants attending Family Health Centers. For the analysis of data, the statistical significance used was p<0.05.</p><p><strong>Results: </strong>Notably, 72.4% of people had at least one vaccination in adulthood. The most frequent vaccinations were tetanus (55.1%), influenza (26.8%), and hepatitis B (8.2%). PATH analysis found that the effect of variables with direct effects on vaccination (apart from the situation of thinking that vaccinations are necessary in adulthood) disappeared in the model in which adult vaccine recommendations were used as mediators.</p><p><strong>Conclusion: </strong>The adult vaccination situation is inadequate. It is necessary to inform society about adult vaccinations and recommend vaccination. Tools such as information given during health services and implementations such as social education and brochures, posters, media, and public information spots may be used with this aim.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241779"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The usefulness of serum procalcitonin levels in predicting surgical intervention in patients with tubo-ovarian abscess.","authors":"Osman Samet Gunkaya, Ayşegül Bestel","doi":"10.1590/1806-9282.20241294","DOIUrl":"https://doi.org/10.1590/1806-9282.20241294","url":null,"abstract":"<p><strong>Objective: </strong>Pelvic inflammatory disease is one of the most common gynecological diseases, and 15% of cases are accompanied by tubal-ovarian abscesses. The aim of this study was to evaluate the usefulness of abscess mass size, serum procalcitonin, and other biochemical markers in patients with tubo-ovarian abscesses in predicting surgical intervention.</p><p><strong>Methods: </strong>This case-control study included 113 women who were diagnosed with tubo-ovarian abscess, hospitalized, and started on antibiotic treatment. Demographic characteristics, biochemical markers, ultrasound findings, and length of hospital stay were recorded during medical treatment.</p><p><strong>Result: </strong>In terms of demographic characteristics, there was no significant difference between cases requiring complete recovery with medical treatment and cases requiring surgery for complete recovery. While serum cancer antigen 125 level was not statistically significant, there was a significant difference among biochemical markers: serum white blood cell level (18,007.0±6,406.3; p=0.001), C-reactive protein level (261.2±122.2; p<0.001), procalcitonin level (0.88±0.46; p<0.001), and abscess mass size (6.1±1.2; p<0.001) in cases that required surgery for full recovery. The highest sensitivity variable predicting surgical intervention in tubo-ovarian abscess patients was abscess mass size (cut-off value>5.25 cm and area under the curve 0.768) with a sensitivity of 72.2%. The second highest sensitivity variant, procalcitonin (cut-off value>0.635 ng/mL and area under the curve 0.756), showed a sensitivity of 70.4%.</p><p><strong>Conclusion: </strong>Although procalcitonin provides information about the severity of the disease in patients with tubo-ovarian abscesses, evaluation of the abscess mass size along with its size was useful in deciding surgical intervention.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241294"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051952/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nazim Serhat Parlak, Süleyman Çağlar Ertekin, Turkay Kırdak
{"title":"The impact of body mass index on the diagnostic and surgical outcomes in primary hyperparathyroidism.","authors":"Nazim Serhat Parlak, Süleyman Çağlar Ertekin, Turkay Kırdak","doi":"10.1590/1806-9282.20240989","DOIUrl":"https://doi.org/10.1590/1806-9282.20240989","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to investigate the influence of body mass index on the diagnostic and surgical outcomes in patients undergoing parathyroidectomy for primary hyperparathyroidism.</p><p><strong>Methods: </strong>A total of 446 patients with primary hyperparathyroidism were divided into four groups according to their body mass index: normal weight (body mass index<25 kg/m2) (n=130), overweight (25≤body mass index<30 kg/m2) (n=166), obese (30≤body mass index<35 kg/m2) (n=112), and morbidly obese (body mass index≥35 kg/m2) (n=38). Perioperative findings were compared between the groups.</p><p><strong>Results: </strong>The preoperative median parathormone level in the morbidly obese group (204 pg/mL, min:max 72:1,178) was significantly lower than that in the normal-weight (246 pg/mL, min:max 60:4,262) (p=0.026) and obese (251 pg/mL, min:max 74:2,094) (p=0.012) groups. The osteoporosis rate in the normal-weight group (51%) was higher than that in the overweight (35.4%) (p=0.041) and morbidly obese (25%) (p=0.023) groups. The symptomatic hypocalcemia rate in the normal-weight group (10.2%) was significantly higher than that in the obese group (1.8%) (p=0.017).</p><p><strong>Conclusion: </strong>Normal-weight patients with primary hyperparathyroidism have higher blood parathormone values, higher rates of osteoporosis, and postoperative symptomatic hypocalcemia compared to patients with higher body mass index. For this reason, the surgeon should consider the possibility of symptomatic hypocalcemia after undergoing parathyroidectomy for primary hyperparathyroidism in normal-weight cases.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20240989"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of head posture in patients with temporomandibular joint disorders: a cross-sectional study.","authors":"Elif Esra Ozmen, Bayram Sonmez Unuvar","doi":"10.1590/1806-9282.20241474","DOIUrl":"https://doi.org/10.1590/1806-9282.20241474","url":null,"abstract":"<p><strong>Objective: </strong>This study evaluated head posture in patients with temporomandibular joint disorders and explored the effects of postural changes on clinical parameters.</p><p><strong>Methods: </strong>In total, 81 individuals diagnosed with temporomandibular joint disorders participated in this cross-sectional prospective study. Demographics, pain status, head posture, and jaw movement data were collected. Head posture was assessed using the Posture Screen Mobile application.</p><p><strong>Results: </strong>Results indicated moderate negative correlations between pain and mouth opening (rho=-0.437, p<0.001) and maximum mouth opening (rho=-0.427, p<0.001). Anterior translation showed weak positive correlations with mouth opening and maximum mouth opening, while right lateral translation exhibited a weak positive correlation with pain (rho=0.264, p=0.017). Posterior angulation showed weak significant correlations with pain, mouth opening, and maximum mouth opening.</p><p><strong>Conclusion: </strong>These findings suggest that head posture has a significant influence on temporomandibular joint disorder symptoms. Treatment strategies addressing postural abnormalities may help alleviate symptoms and enhance the quality of life in temporomandibular joint disorder patients.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241474"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144050720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of myocardial perfusion scintigraphy and strain echocardiography in patients undergoing coronary angiography.","authors":"Çağlar Kaya, Muhammet Gürdoğan","doi":"10.1590/1806-9282.20241806","DOIUrl":"https://doi.org/10.1590/1806-9282.20241806","url":null,"abstract":"<p><strong>Objective: </strong>Myocardial perfusion scintigraphy is a common non-invasive method for assessing ischemic burden, though artifacts can affect accuracy. Speckle-tracking strain echocardiography improves left ventricular function assessment, and global longitudinal strain correlates well with coronary artery disease. The aim of this study was to compare myocardial perfusion scintigraphy with global longitudinal strain in stable angina pectoris patients.</p><p><strong>Methods: </strong>A total of 133 suspected coronary artery disease patients who underwent myocardial perfusion scintigraphy and coronary angiography were prospectively enrolled and classified as myocardial perfusion scintigraphy true positives or false positives based on coronary angiography results. Global longitudinal strain values for the epicardium, endocardium, and myocardium (avg) were calculated.</p><p><strong>Results: </strong>Ischemic percentages of myocardial perfusion scintigraphy>12% and mid-wall global longitudinal strain<-18.4% correlated with true positive coronary angiography results. Left ventricular ejection fraction/global longitudinal strain mid ratio positively correlated with coronary artery disease presence and severity. Higher ischemic percentages of myocardial perfusion scintigraphy showed a negative correlation (r: -0.2606, p: 0.002) with global longitudinal strain, indicating a greater likelihood of coronary artery disease (OR 0.25, 95%CI 0.08-0.73, p: 0.012). Female sex was linked to fewer true positive myocardial perfusion scintigraphy results.</p><p><strong>Conclusion: </strong>The GLS value of the Left Ventricle obtained by two-dimentional strain echocardiography offers sensitivity and specificity similar to myocardial perfusion scintigraphy in the detection of coronary artery disease.. An elevated left ventricular ejection fraction/global longitudinal strain ratio is a significant predictor of the presence and severity of coronary artery disease.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241806"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051942/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Serdar Ceylan, Yelda Ozturk, Merve Guner, Arzu Okyar Bas, Meltem Koca, Cafer Balci, Burcu Balam Dogu, Mustafa Cankurtaran, Meltem Gulhan Halil
{"title":"Can handgrip strength alone detect individuals living with frailty according to the Clinical Frailty Scale?","authors":"Serdar Ceylan, Yelda Ozturk, Merve Guner, Arzu Okyar Bas, Meltem Koca, Cafer Balci, Burcu Balam Dogu, Mustafa Cankurtaran, Meltem Gulhan Halil","doi":"10.1590/1806-9282.20240237","DOIUrl":"https://doi.org/10.1590/1806-9282.20240237","url":null,"abstract":"<p><strong>Objective: </strong>Several studies have been conducted to determine handgrip strength cutoffs that can identify people living with frailty. However, the handgrip strength cutoff value, which can detect individuals living with frailty based on the Clinical Frailty Scale, has not been determined before. The aim of this study was to investigate the capacity of handgrip strength to detect individuals living with frailty by using Clinical Frailty Scale as a reference scale.</p><p><strong>Methods: </strong>This retrospective study was carried out by including patients who applied to the geriatric outpatient clinic of a university hospital. A comprehensive geriatric assessment was performed on all patients. Level 4 and above were considered as living with frailty according to Clinical Frailty Scale. Receiver operating characteristic curve analysis was performed to determine the handgrip strength cutoff values for predicting individuals living with frailty.</p><p><strong>Results: </strong>The median age of 742 patients included in this study was 72.0 years (25p-75p: 68.0-77.0), of which 59.3% (n=440) were female and 49.3% (n=366) were living with frailty. The median Clinical Frailty Scale level was 3.0 (25p-75p: 3.0-4.0). According to the results of binary logistic regression analysis, age, sex, and handgrip strength displayed a statistically significant relationship with frailty (p<0001, p=0.001, and p<0.001, respectively). As a result of the receiver operating characteristic analysis performed to determine the handgrip strength cutoff values that predict frailty, cutoff values of 16 kg for females and 26.7 kg for males were identified. The area under the curve values for females and males were 0.679 (p<0.001) and 0.790 (p<0.001), respectively.</p><p><strong>Conclusion: </strong>Handgrip strength can be used alone as a predictor to identify individuals living with frailty.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20240237"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051968/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144060698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatma Basak Tanoglu, Gurkan Kiran, Caglar Cetin, Burcu Gul, Ozge Pasin, Temel Fatih Yilmaz
{"title":"Diagnostic accuracy of tru-cut biopsy and acid cytology from patients operated with suspicious for ovarian cancer*.","authors":"Fatma Basak Tanoglu, Gurkan Kiran, Caglar Cetin, Burcu Gul, Ozge Pasin, Temel Fatih Yilmaz","doi":"10.1590/1806-9282.20240869","DOIUrl":"https://doi.org/10.1590/1806-9282.20240869","url":null,"abstract":"<p><strong>Objective: </strong>In women who are believed to have ovarian cancer but have a poor performance status or have advanced disease thought to be beyond the scope of primary cytoreductive surgery, neoadjuvant chemotherapy can be administered with acid cytology and/or tru-cut biopsy referral. The aim of this study was to determine the accuracy, adequacy, safety, and reliability of these minimally invasive interventional procedures.</p><p><strong>Methods: </strong>This is a retrospective analysis of 63 patients with a suspicion of ovarian cancer who reported to Bezmialem University Hospital between 2014 and 2021, underwent ultrasound-guided acid cytology and tru-cut biopsy, and also had postoperative final pathology results.</p><p><strong>Results: </strong>On comparing acid cytology and tru-cut biopsy at the same time with the postoperative final pathology results, it was seen that the positive predictive value was 100% in all groups. It was revealed that the sensitivity of acid cytology was 64%, the specificity was 100%, the negative predictive value was 12%, and the accuracy of the test was 65%. The sensitivity of the tru-cut biopsy was 91%, the specificity was 100%, the negative predictive value was 42%, and the accuracy of the test was 92%. In the case of both procedures, the sensitivity was calculated as 93% and the accuracy of the test was calculated as 93%. There were no false-positive cytology and biopsy results.</p><p><strong>Conclusion: </strong>Due to its high reliability and accuracy, the combined application of these minimally invasive methods has the potential to routinely replace more invasive methods for adequate tumor sampling, such as diagnostic laparoscopy or exploratory laparotomy.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20240869"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051969/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tugba Kinay, Sule Atalay Mert, Rahmi Sinan Karadeniz, Yaprak Engin Ustun
{"title":"Association between the physical activity level in the third trimester of pregnancy and the gestational age at birth.","authors":"Tugba Kinay, Sule Atalay Mert, Rahmi Sinan Karadeniz, Yaprak Engin Ustun","doi":"10.1590/1806-9282.20241509","DOIUrl":"https://doi.org/10.1590/1806-9282.20241509","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the association between the physical activity level in the third trimester and the time of labor onset.</p><p><strong>Methods: </strong>Two hundred and sixty women with low-risk pregnancies, who gave birth at 37 weeks of gestation or beyond, and completed the Pregnancy Physical Activity Questionnaire were included in this prospective, cross-sectional study. According to the gestational age at delivery, the study population was divided into case (≥41 weeks) and control (37-406/7 weeks) groups. The clinical characteristics and the physical activity levels of the two groups were compared. The physical activity levels of the participants were also compared according to the delivery route.</p><p><strong>Results: </strong>The nulliparity rate (54.3 vs. 21.7%), the median gestational weight gain (10.5 [2-30] vs. 10 [2-25] kg), and the cesarean delivery rate (27.7 vs. 6.6%) were higher in the case group than the control group (p<0.05). While the median level of sedentary activity was higher, the median moderate-intensity activity level and the median household/caregiving activity level were lower in the case group than the control group (p<0.05). The level of sedentary activity was also higher in women who gave birth by a cesarean section than vaginally (p<0.05).</p><p><strong>Conclusion: </strong>Physical activity in the third trimester was associated with the time of labor onset. Decreased moderate-intensity and household/caregiving activity levels and an increased level of sedentary activity in the last trimester of pregnancy were found in women who gave birth at ≥41 weeks of gestation. A decreased level of sedentary activity was observed in women who gave birth vaginally.</p>","PeriodicalId":94194,"journal":{"name":"Revista da Associacao Medica Brasileira (1992)","volume":"71 3","pages":"e20241509"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051944/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144028446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}