Resuscitation plus最新文献

{"title":"Temporal trends in post-cardiac arrest brain injury research: a bibliometric analysis of evolving priorities and translation gaps","authors":"Guanhong Liu,&nbsp;Mengchi Chen,&nbsp;Yongmei Fu,&nbsp;Rui Gong,&nbsp;Yongbiao Zhang,&nbsp;Xinxin Cheng,&nbsp;Chunxin Liu","doi":"10.1016/j.resplu.2026.101421","DOIUrl":"10.1016/j.resplu.2026.101421","url":null,"abstract":"<div><h3>Background</h3><div>Post-cardiac arrest brain injury (PCABI) is a major determinant of outcomes after cardiac arrest (CA), yet effective neuroprotective interventions remain limited. Although PCABI research has expanded rapidly, a systematic bibliometric evaluation of evolving research priorities and their relationship with translational and clinical evidence gaps remains lacking.</div></div><div><h3>Objective</h3><div>To evaluate temporal shifts in PCABI research priorities over the past decade and to explore how evolving bibliometric trends relate to major areas of clinical evidence.</div></div><div><h3>Methods</h3><div>PCABI-related articles and reviews published from 2016 to 2025 were retrieved from the Web of Science Core Collection and analyzed using VOSviewer, CiteSpace, and bibliometrix for publication trends, collaboration networks, keyword evolution, burst patterns, co-citation, and disciplinary distribution.</div></div><div><h3>Results</h3><div>A total of 3068 publications were included. Annual output showed an overall upward trajectory, increasing from 229 publications in 2016 to 381 in 2025, with the highest annual contribution observed in 2025. Keyword evolution analysis indicated a shift from therapeutic hypothermia and ischemic brain injury mechanisms toward post-resuscitation care, neurological prognostication, extracorporeal support, neuroimaging, disorders of consciousness, and evidence synthesis. Co-citation analysis showed that the historical intellectual structure of the field remained strongly influenced by landmark temperature-management studies, post-cardiac arrest care guidelines, and foundational pathophysiological publications.</div></div><div><h3>Conclusion</h3><div>PCABI-related research has expanded substantially and shifted from temperature management and ischemic injury mechanisms toward broader clinical priorities. However, many emerging directions still require stronger prospective validation. Future research may prioritize multimodal prognostic strategies, bundled post-cardiac arrest care, and clinically translatable neuroprotective interventions.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101421"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Insights from a multinational survey on ERC courses: a cross-sectional analysis of participant and instructor perspectives","authors":"Vlasios Karageorgos,&nbsp;Timo de Raad,&nbsp;Sander van Goor,&nbsp;Francesc Carmona Jimenez,&nbsp;Andrew S. Lockey,&nbsp;Robert Greif,&nbsp;Carsten Lott","doi":"10.1016/j.resplu.2026.101379","DOIUrl":"10.1016/j.resplu.2026.101379","url":null,"abstract":"<div><h3>Background</h3><div>European Resuscitation Council (ERC) life support courses are delivered internationally to standardise resuscitation. Given advances in educational science, evolving learner needs, and rapid technological innovation, ongoing evaluation is required to ensure these courses continue to meet expectations. This study aimed to identify priorities for course delivery, teaching and assessment strategies, and to inform future course development.</div></div><div><h3>Methods</h3><div>From May to June 2025, the ERC Course Strategy Taskforce conducted two web-based surveys among course participants and instructors (10 and 22 items, respectively). The surveys included single-response items, Likert-scale ratings, and open-text questions addressing teaching background, course delivery, assessment practices, and views on course structure and materials. Data were analysed using a mixed-methods approach, with descriptive statistics applied to quantitative data and inductive thematic analysis to qualitative responses.</div></div><div><h3>Results</h3><div>Responses from 13,989 participants and 1923 unique instructors across all ERC course types were analysed. Participant satisfaction was high (mean 9.13/10); 92.8% reported increased confidence in real-life resuscitation, and 99.5% rated the on-site component positively. Instructors favoured continuous assessment for evaluating technical skills (95.2%), non-technical skills (92.5%), and professional attitudes (96.2%), with 87.1% supporting its combination with a summative endpoint. Pre-course multiple choice question testing (85.7%) and mandatory instructor preparation (90.8%) were widely endorsed. Qualitative findings highlighted the need to further develop the ERC Course System, expand specialised content, and enable more personalised delivery formats.</div></div><div><h3>Conclusion</h3><div>ERC courses are highly valued and should evolve towards competency-based assessment, structured faculty development, and enhanced digital infrastructure to maintain relevance, inclusivity, and educational impact.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101379"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13320541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of team size on the efficiency of time-critical ALS interventions in prehospital cardiac arrest – A prospective randomised multicentre simulation study","authors":"Sophie Franziska L’habitant,&nbsp;Alina Schenk,&nbsp;Marcus Thudium,&nbsp;Mark Coburn,&nbsp;Alexander Lechleuthner,&nbsp;Florian Piekarski","doi":"10.1016/j.resplu.2026.101384","DOIUrl":"10.1016/j.resplu.2026.101384","url":null,"abstract":"<div><h3>Objective</h3><div>To determine whether increasing emergency medical service (EMS) team size improves the efficiency of time-critical invasive procedures during advanced life support (ALS) for out-of-hospital cardiac arrest (OHCA).</div></div><div><h3>Design</h3><div>Randomised prospective multicentre simulation study with a parallel-group comparison of four predefined team sizes.</div></div><div><h3>Setting</h3><div>Three accredited EMS training centres in North Rhine-Westphalia, Germany.</div></div><div><h3>Participants</h3><div>210 ALS-trained paramedic students allocated to 59 teams of two to five members.</div></div><div><h3>Interventions</h3><div>Teams managed a standardised adult ALS scenario (persistent ventricular fibrillation) requiring five invasive procedures: manual defibrillation, supraglottic airway insertion, intravenous access, preparation of amiodarone (300 mg), and preparation of epinephrine (1 mg).</div></div><div><h3>Measurements and main results</h3><div>The primary endpoint was total scenario time from start to completion of the final procedure. Secondary endpoints were start and completion times for each intervention. Mean total times (mm:ss) decreased progressively with team size: two-person 6:33 ± 0:33 min, three-person 4:13 ± 0:40 min, four-person 2:54 ± 0:24 min, and five-person 2:14 ± 0:19 min (ANOVA, <em>p</em> &lt; 0.001). All pairwise differences were statistically significant (Bonferroni-corrected <em>p</em>_adj &lt; 0.01). Earlier initiation of intravenous access and drug preparation accounted for most time savings. All teams completed every task successfully.</div></div><div><h3>Conclusions</h3><div>Larger EMS teams performed time-critical ALS procedures significantly faster, with optimal efficiency observed in four- to five-member crews. These findings highlight the operational importance of team composition for prehospital resuscitation performance and may inform staffing policies and simulation-based training.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101384"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13320515/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148371550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subarachnoid hemorrhage presenting as cardiac arrest mimicking acute myocardial infarction due to multivessel coronary vasospasm: a case report","authors":"Yukako Otsuka,&nbsp;Fumiko Nakamura,&nbsp;Kenta Uemura,&nbsp;Hiroto Yamamoto,&nbsp;Riki Kitahashi,&nbsp;Yoichi Tsutano,&nbsp;Kazuhiro Kobuke,&nbsp;Takeshi Aoyama,&nbsp;Norio Kanamori","doi":"10.1016/j.resplu.2026.101391","DOIUrl":"10.1016/j.resplu.2026.101391","url":null,"abstract":"<div><div>A 58-year-old man presented with out-of-hospital cardiac arrest. The initial rhythm was pulseless electrical activity, which deteriorated into ventricular fibrillation during resuscitation. After return of spontaneous circulation, electrocardiography demonstrated diffuse ST-segment depression with ST-segment elevation in lead aVR, strongly suggesting acute coronary syndrome. Emergent coronary angiography revealed simultaneous angiographic occlusion with TIMI 0 flow in the ostial left anterior descending artery and distal right coronary artery. During preparation for percutaneous coronary intervention, coronary flow spontaneously recovered to TIMI 3 without balloon dilation, stenting, or intracoronary vasodilator administration. Intravascular ultrasound demonstrated no plaque rupture or thrombus. Persistent coma prompted neuroimaging, which revealed diffuse subarachnoid hemorrhage with hydrocephalus. Although cardiac arrest associated with subarachnoid hemorrhage usually presents with non-shockable rhythms, this case demonstrated recurrent ventricular fibrillation and transient multivessel coronary occlusion closely mimicking acute myocardial infarction.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101391"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13331965/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric cardiopulmonary resuscitation quality in crib versus standard hospital bed model at a single center","authors":"Ava R. Wilstead,&nbsp;Ken Tegtmeyer,&nbsp;Kelly Collins,&nbsp;Andrea R. Meisman,&nbsp;Kyesha James,&nbsp;Bin Zhang,&nbsp;Rashmi D. Sahay,&nbsp;Matthew W. Zackoff,&nbsp;Daniel A. Loeb,&nbsp;Maya L. Dewan","doi":"10.1016/j.resplu.2026.101395","DOIUrl":"10.1016/j.resplu.2026.101395","url":null,"abstract":"<div><h3>Background</h3><div>The influence of crib design on the quality of cardiopulmonary resuscitation (CPR) during in-hospital cardiac arrest (IHCA) in pediatric settings remains largely understudied. This study investigates the association between bed type and CPR quality metrics in the pediatric intensive care.</div></div><div><h3>Methods</h3><div>A retrospective, single-center observational cohort study of pediatric patients &lt;3 years of age requiring CPR in the pediatric intensive care unit of a free-standing children’s hospital between January 1, 2017 and May 31, 2025. CPR quality metrics including chest compression (CC) rate, depth, and fraction were compared between patients who experienced IHCA in a specialized hospital crib versus other bed types.</div></div><div><h3>Results</h3><div>Forty-nine IHCA events were analyzed, with 23 events occurring in specialized hospital cribs. There was no difference between CC depth and rate between groups for children &lt;3 years of age, while median CC fraction was higher in the specialized crib group (0.94 [IQR 0.89–0.98]) compared with standard surfaces (0.85 [IQR 0.76–0.95]; <em>p</em> = 0.01). Among patients &lt;1 year of age, median CC rate was at 112/min (IQR 108–114) in the specialized crib group compared with 115/min (IQR 113–119) on standard surfaces (<em>p</em> = 0.04). No significant differences were observed in CC fraction or depth for children less than one year of age.</div></div><div><h3>Conclusion</h3><div>In this single center study, there was no negative impact of specialized medical crib use on CPR quality metrics. Further studies are necessary to evaluate patient and rescuer specific factors that may be impacted by pediatric bed ergonomics.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101395"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13352390/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Representation of female and male pictorial instructions on automated external defibrillators, pad packages, and defibrillation pads","authors":"Nino Fijačko,&nbsp;Robert Greif,&nbsp;Guglielmo Imbriaco,&nbsp;Priyanka Modi,&nbsp;Roos Edgar,&nbsp;Kristin Alm-Kruse,&nbsp;Sergio Cazorla-Calderón","doi":"10.1016/j.resplu.2026.101259","DOIUrl":"10.1016/j.resplu.2026.101259","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the representation of sex pictograms displayed on automated external defibrillators (AEDs), pad packages, and defibrillation pads, assessing inclusivity and potential implications for real-life AED use.</div></div><div><h3>Methods</h3><div>Between May and October 2025, investigators from seven countries worldwide captured original photographs of AEDs, pad packages, and defibrillation pads from manufacturers, distributors, and institutional networks. Only adult, commercially available AEDs and defibrillation pads intended for real-life use were included; training or manual AEDs were excluded. Two independent researchers assessed each pictogram for sex representation, with consensus by a third reviewer when needed.</div></div><div><h3>Results</h3><div>Female pictograms were rare across all reviewed AEDs, pad packages, and defibrillation pad sets. Among 51 AEDs with pictograms, only two (3.9%) included any female pictograms, whereas most displayed only adult male pictograms (62.7%). In pad packages, female pictograms appeared on three packages (7.0%), while 48.8% showed only adult male pictograms. In defibrillation pad sets, female pictograms appeared in two sets (4.5%); most showed only adult male pictograms (56.8%). Neonatal and pediatric pictograms were uncommon overall, with pediatric boy pictograms representing the predominant across AEDs, pad packages, and defibrillation pad sets.</div></div><div><h3>Conclusions</h3><div>Instructional imagery on AEDs, pad packages, and defibrillation pads overwhelmingly represents male, with minimal or absent female depictions. This imbalance may reinforce gender bias, potentially leading to incorrect pad placement on women and reducing inclusivity in resuscitation. Manufacturers and resuscitation councils could promote accurate and balanced visual representations to ensure equitable and realistic AED use across sexes and body types during cardiac arrest management.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101259"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148737187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive cerebral oxygenation and blood pressure neuromonitoring characterizes dynamic cerebrovascular autoregulation following cardiac arrest","authors":"Rachel Beekman,&nbsp;Christine Nguyen,&nbsp;Lily Pwint Thinzar,&nbsp;Mark Warman,&nbsp;Noah Kim,&nbsp;William McCarthy,&nbsp;Akhil Khosla,&nbsp;Shyoko Honiden,&nbsp;Dawn Cooper,&nbsp;Guido J. Falcone,&nbsp;Jessica Magid-Bernstein,&nbsp;Stefanie P. Cappucci,&nbsp;Jennifer A. Kim,&nbsp;Kevin N. Sheth,&nbsp;Nils H. Petersen,&nbsp;Emily J. Gilmore","doi":"10.1016/j.resplu.2026.101409","DOIUrl":"10.1016/j.resplu.2026.101409","url":null,"abstract":"<div><h3>Background and purpose</h3><div>Cerebrovascular autoregulation (CVAR) is impaired following cardiac arrest. We describe near-infrared spectroscopy (NIRS)-derived CVAR parameters following cardiac arrest and characterize their evolution over time.</div></div><div><h3>Methods</h3><div>This was a retrospective analysis of a prospectively collected clinical and physiological cardiac arrest data repository at a single academic medical center between March 2022 and October 2023. Eligible patients were connected to neuromonitoring within 72 h of cardiac arrest, had greater than four hours of monitoring, and had no confounding neurologic diagnosis. NIRS derived cerebral oxygenation index (COx) and limits of autoregulation were computed using the linear correlation between time-synchronized regional cerebral oxygenation (rSO₂) and continuous mean arterial pressure (MAP). CVAR limits [inclusive of optimal MAP (MAP_OPT), lower limit of autoregulation (LLA), and upper limit of autoregulation (ULA)] were determined using a fitted COx versus MAP parabolic curve with a COx threshold of 0.3.</div></div><div><h3>Results</h3><div>Of 60 eligible patients, 56 underwent neuromonitoring, and 55 were included in this analysis. Mean (standard deviation [SD]) age was 53.4 (15.4) years, and the majority had high severity of post-cardiac arrest syndrome. The median (interquartile range) time from cardiac arrest to first recorded COx was 14.2 (10.1–21.2) h; median monitoring duration was 49.1 (26.6–85.3) h. Mean (SD) MAP_OPT and limits of autoregulation were 86.0 (13.1) mmHg and 74.6 (11.3)–96.8 (13.0) mmHg, respectively. The LLA was ≥65 mmHg in 85.5% (<em>n</em> = 47) of patients. All patients had at least one epoch of impaired or dysfunctional CVAR. Thirteen patients (23.6%) survived to hospital discharge. Survivors had a higher MAP (91.6 vs 82.7 mmHg, <em>p</em> = 0.039) and lower COx (0.05 vs 0.15, <em>p</em> = 0.041) than non-survivors.</div></div><div><h3>Conclusion</h3><div>Impaired CVAR was common and dynamic over at least 120 h following cardiac arrest. If a population-based MAP threshold of ≥65 mmHg were applied to our cohort, it may have resulted in significant time burden below the LLA. While it was feasible to determine CVAR limits, further work is needed to identify if CVAR-based treatment approaches influence outcomes.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101409"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13393843/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148581871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early alveolar molecular signatures after cardiopulmonary resuscitation: a bronchoalveolar lavage (BALF) proteomic study in swine","authors":"Joaquin Araos,&nbsp;Felipe Teran,&nbsp;Clark Owyang,&nbsp;Derek Lao,&nbsp;Congli Zeng,&nbsp;Marcos Vidal Melo,&nbsp;Qin Fu,&nbsp;Rory C. Chien,&nbsp;Michael Garenani,&nbsp;Manuel Martin-Flores,&nbsp;Marta Cercone","doi":"10.1016/j.resplu.2026.101405","DOIUrl":"10.1016/j.resplu.2026.101405","url":null,"abstract":"<div><h3>Background</h3><div>Mechanical chest compressions during cardiopulmonary resuscitation (CPR) can produce pulmonary edema, described as cardiopulmonary resuscitation–associated lung edema (CRALE), which has been largely interpreted as a hydrostatic phenomenon. However, whether early molecular changes associated with epithelial injury, coagulation, and inflammation are also present during resuscitation remains uncertain. We hypothesized that bronchoalveolar lavage fluid proteomics would identify early protein signatures of lung injury after CPR.</div></div><div><h3>Methods</h3><div>Bronchoalveolar lavage fluid (BALF) was collected separately from the right and left caudal lung lobes of nine pigs before cardiac arrest and again after ventricular fibrillation, 8 min of untreated arrest, and up to 45 min of CPR. In animals achieving return of spontaneous circulation, post-CPR BALF was obtained immediately after resuscitation; in the remaining animals, sampling was performed at the end of CPR. Proteins were digested, tandem mass tag 18-plex labeled, and analyzed by high-resolution liquid chromatography–mass spectrometry. Differentially abundant proteins were defined by fold change &gt;1.5 or &lt;0.67 with <em>P</em> &lt; 0.05. Functional enrichment, histologic assessment, and western blot validation were performed.</div></div><div><h3>Results</h3><div>A total of 1088 proteins were identified in left lung BALF and 1200 in right lung BALF. Comparison of pre- and post-CPR samples identified 74 and 78 differentially abundant proteins in the left and right lungs, respectively, with 28 shared proteins across both lungs. Among the most increased proteins were plasminogen activator inhibitor-1 (SERPINE1/PAI-1), apolipoprotein A1, inter-alpha inhibitor family proteins, vitronectin, histones, and advanced glycation end-product receptor (AGER). Functional enrichment showed over-representation of proteins related to complement and coagulation, platelet degranulation, lipid metabolism, and extracellular matrix signaling. Histology showed mild septal thickening, vascular neutrophilic infiltration, interstitial edema, and patchy fibrin deposition, consistent with early pneumocyte injury and mild inflammation. Western blot confirmed increased post-CPR abundance of PAI-1 and apolipoprotein A1.</div></div><div><h3>Conclusions</h3><div>Early after resuscitation, BALF proteomics identified molecular changes characterized by increased antifibrinolytic and complement-related proteins, together with proteins associated with epithelial and endothelial stress. These findings suggest that pulmonary abnormalities after CPR may involve not only hydrostatic edema but also an early biologic response consistent with lung injury, which may contribute to post-cardiac arrest respiratory dysfunction and progression to acute respiratory distress syndrome.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101405"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148634659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leveraging primary healthcare institutions for the deployment of automated external defibrillators: a geospatial optimization analysis in Deyang, China","authors":"Sheng Liu,&nbsp;Chunyan Liao,&nbsp;Yi Yang,&nbsp;Yong Yang,&nbsp;Wei Jiang,&nbsp;Dingxiu He,&nbsp;Kaisen Huang","doi":"10.1016/j.resplu.2026.101369","DOIUrl":"10.1016/j.resplu.2026.101369","url":null,"abstract":"<div><h3>Aim</h3><div>To analyze the spatial and epidemiological characteristics of out-of-hospital cardiac arrest (OHCA) in Deyang, China (2021–2023), quantify the supply–demand coverage gap in current automated external defibrillator (AED) placement, and evaluate a geospatial optimization strategy embedding AEDs in 24/7 accessible outdoor cabinets at primary healthcare institutions (PHCIs).</div></div><div><h3>Methods</h3><div>We integrated data on OHCA cases, existing AEDs, PHCIs, and demographics. Temporal variations were assessed via descriptive epidemiology, while spatial heterogeneity was characterized via Global/Local Moran’s I and Getis-Ord Gi* hotspot analysis. A network analysis model integrating the Gaussian Two-Step Floating Catchment Area (Ga2SFCA) method and the Maximal Covering Location Problem (MCLP) was constructed using PHCIs as candidate nodes based on road network distance. Optimization was simulated under two scenarios: complete redistribution and incremental expansion.</div></div><div><h3>Results</h3><div>The study included 3273 OHCA cases. Significant temporal variations were observed, with peak incidence during morning hours and public holidays. Spatial autocorrelation indicated intensifying OHCA clustering from 2021 to 2023 (Moran’s I: 0.38–0.49, <em>P</em> &lt; 0.01). Furthermore, spatial analysis revealed a stable ‘core-periphery’ structure, with Jingyang District identified as a consistent high disease burden hotspot. A marked supply–demand coverage gap was observed: residential areas accounted for 82.22% of cases but only 6.29% of AED deployments. Existing AEDs covered only 31.87% of historical OHCAs within a 500-m road network distance. The new Optimized Model for Network Analysis demonstrated that achieving &gt;50% coverage required 100 additional AEDs under a complete redistribution strategy, versus 200 under an incremental expansion strategy.</div></div><div><h3>Conclusion</h3><div>The distribution of OHCA incidence exhibits distinct epidemiological patterns, significant spatial clustering, and a marked disconnect from current AED placement. A geospatial optimization strategy leveraging the extensive network of PHCIs significantly enhances coverage efficiency. This “PHCI-embedded” model provides a cost-effective framework for establishing resilient cardiac arrest response systems in resource-constrained urban settings.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101369"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13332458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148392968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological barriers to bystander AED use: Associations of empathy with willingness to perform bystander rescue behaviors","authors":"Koichi Takaishi,&nbsp;Hideko Kono,&nbsp;Masaya Onuma,&nbsp;Michi Fukushima,&nbsp;Ryosuke Takeuchi","doi":"10.1016/j.resplu.2026.101394","DOIUrl":"10.1016/j.resplu.2026.101394","url":null,"abstract":"<div><h3>Background</h3><div>Despite public access to automated external defibrillators (AEDs), bystander use remains limited. The psychological factors influencing rescue behaviors are not well understood.</div></div><div><h3>Objective</h3><div>To examine how three empathy dimensions (empathic concern, perspective-taking, and personal distress) are associated with willingness to intervene in bystander rescue behaviors.</div></div><div><h3>Methods</h3><div>A cross-sectional survey of laypersons from Japan recruited using a nationwide online research panel operated by a commercial company was conducted using hypothetical train-station cardiac arrest scenarios. Participants rated their willingness to perform three rescue behaviors—running up to the victim or calling for help, retrieving an AED, and using an AED—on a 5-point Likert scale, with high willingness indicated by scores of 4–5. Univariable and multivariable logistic regression analyses were performed to examine associations between empathy dimensions and willingness to intervene.</div></div><div><h3>Results</h3><div>Overall, 1050 participants were included. High willingness was most frequent for running up to the victim or calling for help (72.6%), followed by retrieving an AED (40.6%), and using an AED (25.7%). Higher empathic concern was associated with greater willingness across all three rescue behaviors. Similar patterns were observed in univariable analyses and after multivariable adjustment. Perspective-taking was positively associated mainly with AED-related behaviors, whereas personal distress was inversely associated with willingness to retrieve and use an AED.</div></div><div><h3>Conclusions</h3><div>Distinct empathy dimensions may play different roles depending on the type of rescue behavior. Empathic concern and perspective-taking may facilitate AED-related actions, whereas personal distress may represent a psychological barrier. Interventions targeting emotion regulation and perspective-taking may help improve bystander AED use.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"30 ","pages":"Article 101394"},"PeriodicalIF":3.1,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13351882/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148427857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}