Extracorporeal membrane oxygenation combined with prone ventilation for the treatment of high-dose metoprolol and amlodipine poisoning: A case report

Abstract

Extracorporeal life support (ECLS) represents the ultimate intervention for respiratory and circulatory failure. By maintaining hemodynamic stability, ECLS facilitates drug metabolism and organ recovery, thereby improving survival outcomes. We report a case of severe respiratory and circulatory failure resulting from the oral ingestion of 35 extended-release metoprolol tablets (25 mg each) and 100 extended-release amlodipine tablets (5 mg each). The patient responded favorably to venoarterial extracorporeal membrane oxygenation (VA-ECMO) combined with prone-position ventilation.