Zhiwen Zhao , Bo Wang , Daiqiang Liu , Wengtao Tao , Haowen Tang , Zeyu Wu , Xiaolin Zhang , Zhicheng Fang
{"title":"体外膜氧合联合俯卧位通气治疗大剂量美托洛尔氨氯地平中毒1例","authors":"Zhiwen Zhao , Bo Wang , Daiqiang Liu , Wengtao Tao , Haowen Tang , Zeyu Wu , Xiaolin Zhang , Zhicheng Fang","doi":"10.1016/j.resplu.2025.101059","DOIUrl":null,"url":null,"abstract":"<div><div>Extracorporeal life support (ECLS) represents the ultimate intervention for respiratory and circulatory failure. By maintaining hemodynamic stability, ECLS facilitates drug metabolism and organ recovery, thereby improving survival outcomes. We report a case of severe respiratory and circulatory failure resulting from the oral ingestion of 35 extended-release metoprolol tablets (25 mg each) and 100 extended-release amlodipine tablets (5 mg each). The patient responded favorably to venoarterial extracorporeal membrane oxygenation (VA-ECMO) combined with prone-position ventilation.</div></div>","PeriodicalId":94192,"journal":{"name":"Resuscitation plus","volume":"26 ","pages":"Article 101059"},"PeriodicalIF":2.4000,"publicationDate":"2025-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Extracorporeal membrane oxygenation combined with prone ventilation for the treatment of high-dose metoprolol and amlodipine poisoning: A case report\",\"authors\":\"Zhiwen Zhao , Bo Wang , Daiqiang Liu , Wengtao Tao , Haowen Tang , Zeyu Wu , Xiaolin Zhang , Zhicheng Fang\",\"doi\":\"10.1016/j.resplu.2025.101059\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Extracorporeal life support (ECLS) represents the ultimate intervention for respiratory and circulatory failure. By maintaining hemodynamic stability, ECLS facilitates drug metabolism and organ recovery, thereby improving survival outcomes. We report a case of severe respiratory and circulatory failure resulting from the oral ingestion of 35 extended-release metoprolol tablets (25 mg each) and 100 extended-release amlodipine tablets (5 mg each). The patient responded favorably to venoarterial extracorporeal membrane oxygenation (VA-ECMO) combined with prone-position ventilation.</div></div>\",\"PeriodicalId\":94192,\"journal\":{\"name\":\"Resuscitation plus\",\"volume\":\"26 \",\"pages\":\"Article 101059\"},\"PeriodicalIF\":2.4000,\"publicationDate\":\"2025-08-13\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Resuscitation plus\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2666520425001961\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CRITICAL CARE MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Resuscitation plus","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2666520425001961","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CRITICAL CARE MEDICINE","Score":null,"Total":0}
Extracorporeal membrane oxygenation combined with prone ventilation for the treatment of high-dose metoprolol and amlodipine poisoning: A case report
Extracorporeal life support (ECLS) represents the ultimate intervention for respiratory and circulatory failure. By maintaining hemodynamic stability, ECLS facilitates drug metabolism and organ recovery, thereby improving survival outcomes. We report a case of severe respiratory and circulatory failure resulting from the oral ingestion of 35 extended-release metoprolol tablets (25 mg each) and 100 extended-release amlodipine tablets (5 mg each). The patient responded favorably to venoarterial extracorporeal membrane oxygenation (VA-ECMO) combined with prone-position ventilation.