Photobiomodulation, photomedicine, and laser surgery最新文献

{"title":"Lens Fragmentation with Picosecond Laser Pulses After Artificial Cataract Induction with Microwaves.","authors":"Michael Körber, Andreas Giese, Manfred Kottcke, Francesco Luciani, Josef M Schmidbauer, Bernd Braun","doi":"10.1089/photob.2024.0062","DOIUrl":"10.1089/photob.2024.0062","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> In this work we demonstrate the first laboratory study results of lens fragmentation with low-energy picosecond ultrashort laser pulses after artificial induction of cataract with microwave radiation on an ex vivo animal model. <b><i>Background:</i></b> This method will be evaluated with regard to the further development of lens fragmentation with novel ultrashort picosecond laser systems instead of ultrasonic phacoemulsification or the significantly more complex femtosecond laser fragmentation. <b><i>Methods:</i></b> As samples we used postmortem porcine eyes. The lenses were dissected and then irradiated in a microwave oven for artificial cataract induction. Subsequent computer-driven lens fragmentation was performed with a 12 ps, 1064 nm pulsed laser source with 100 µJ pulse energy, and 10 kHz pulse repetition rate. <b><i>Results:</i></b> Both the artificial cataract induction and the lens fragmentation were demonstrated. When inducing cataract, different degrees/stages of opaqueness and hardness could be achieved with different irradiation times and methods. The fragmentation with 12 ps pulses led to good results with regard to ablation depth and rate, especially for the softer lenses. <b><i>Conclusions:</i></b> As could be shown, low-energy picosecond ultrashort laser pulses are feasible for cataractous lens fragmentation on an ex vivo animal model with artificial cataract induction. Thus, this technique may influence future cataract surgeries by possibly being an alternative or extension to state-of-the-art methods. This will be evaluated with further tests and studies.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"534-540"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Delayed Photobiomodulation Therapy on Inferior Alveolar Nerve Recovery After Third Molar Removal: A Triple-Blinded Randomized Clinical Trial.","authors":"Amir Yari, Paniz Fasih, Saeideh Sadeghi, Emad Movahed, Soroush Hallajmoghaddam Sarand, Ali Goodarzi","doi":"10.1089/pho.2024.0016","DOIUrl":"10.1089/pho.2024.0016","url":null,"abstract":"<p><p><b><i>Background:</i></b> Third molar removal is the primary reason for inferior alveolar nerve (IAN) damage, with 2% causing persistent neurosensory deficits. This study aimed to investigate how delayed photobiomodulation therapy affects long-lasting neurosensory disturbances. <b><i>Methods:</i></b> This study was conducted on patients with neurosensory disturbances lasting longer than 6 months. Patients were randomly allocated to the study and control groups, with the study group receiving a low-power diode laser (continuous wavelength of 810 nm, power of 200 mW) on 16 points (30 sec at each) for 12 sessions (2 sessions/week), while the control group received a placebo treatment by switched-off laser probe. Visual analog scale (VAS; ranging from 1 to 5), static light touch, two-point discrimination, direction discrimination, pinprick, and thermal discrimination tests were performed on each visit up to 9 months post-therapy to evaluate the recovery status. <b><i>Results:</i></b> Each group comprised 18 participants. The mean time since injury was 8.26 ± 2.05 and 8.38 ± 1.98 months for the control and intervention groups, respectively (<i>p</i> = 0.81). There was a significant improvement in the intervention group on the static light touch (<i>p</i> = 0.041), two-point discrimination (<i>p</i> = 0.028), VAS (<i>p</i> = 0.031), and pinprick (<i>p</i> = 0.014) tests on the 11th session and subsequent visits and also on direction discrimination test on the 12th session (<i>p</i> = 0.044) and after that. There was no significant difference in the thermal discrimination tests between the two groups (<i>p</i> > 0.05). <b><i>Conclusion:</i></b> Photobiomodulation demonstrated potential benefits in resolving persistent neurosensory deficits of the IAN, with noticeable improvements typically observed after around 35 days of treatment initiation (10 sessions).</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"463-472"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation Literature Watch September 2023.","authors":"James D Carroll","doi":"10.1089/pho.2024.0084","DOIUrl":"10.1089/pho.2024.0084","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"498-500"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141556477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Photobiomodulation in the Treatment of Dysgeusia in Patients with Long COVID: A Single-Blind, Randomized Controlled Trial.","authors":"Carlos Eduardo Fontana, Letícia Parreira, Sérgio Pinheiro","doi":"10.1089/pho.2024.0045","DOIUrl":"10.1089/pho.2024.0045","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"438"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Er:YAG Laser and Hemolasertherapy: Bone and Gingiva Gain-Case Report.","authors":"Fatima Zanin, Gabriela Silva, Eric Mayer-Santos, Ana Paula Brugnera, Ariane Sardop, Aldo Brugnera","doi":"10.1089/pho.2023.0138","DOIUrl":"10.1089/pho.2023.0138","url":null,"abstract":"<p><p><b><i>Background:</i></b> Modern dentistry has increasingly valued conservative and biologically less invasive clinical practices, seeking to preserve the patients' tissues and natural dental elements. Most extractions in the dental clinic are preceded by periodontal disease that presents bone and gingival tissue loss, compromising the aesthetics as well as the support of dental elements. <b><i>Objectives:</i></b> The clinical approach in these cases often involves bone exertion followed by the successful installation of osseointegrated implants. <b><i>Material and Methods:</i></b> In this study, a case of extensive periodontal involvement and mobility of dental elements was carried out in a minimally invasive way, using the Er:YAG laser for periodontal decontamination and the hemolasertherapy technique to regenerate adjacent tissues, totaling nine weeks of treatment. <b><i>Results:</i></b> Clinical and radiographical improvement of tissue health and complete preservation of dental elements were observed. <b><i>Conclusion:</i></b> The patient underwent a follow-up appointment 2 years after the start of treatment when it was still possible to verify the stability of the clinical condition and the tissue gains obtained.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"493-497"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140961352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fractional and Microablative CO₂ LASER and Radiofrequency in the Treatment of Genitourinary Syndrome of Menopause: A Descriptive Study.","authors":"Maria Cristina Caceres Nogueira, Ana Maria Homem de Mello Bianchi-Ferraro, Madalena Leonor Pereira Campos, Carla Dias Oliveira, Marair Gracio Ferreira Sartori, Zsuzsanna Ilona Katalin de Jármy Di Bella, Angela Flavia Logullo, Neila Maria Gois Speck","doi":"10.1089/pho.2023.0110","DOIUrl":"10.1089/pho.2023.0110","url":null,"abstract":"<p><p><b><i>Objectives:</i></b> This study aimed to evaluate the vagina clinically, cytologically, and histologically before and after treating genitourinary syndrome of menopause (GSM) with fractional microablative carbon dioxide LASER (CO₂L), radiofrequency (RF), and estrogen vaginal cream (CT). <b><i>Methods:</i></b> Women with moderate-to-severe symptoms of GSM, denoted by a GSM Visual analog scale (VAS) score of >4, were eligible for this study. The patients were randomized into treatment groups. In the energy groups, three vulvovaginal applications were administered monthly. The CT group used 0.5 mg vaginal estriol cream for 14 consecutive days, followed by twice a week for 4 months. The follow-up visits occurred 120 days after the beginning of the treatments. The same parameters obtained at the first visit were re-evaluated: GSM VAS score, Incontinence Quality of Life Questionnaire (I-QOL), gynecological examination determining Vaginal Health Index (VHI), vaginal smear for Vaginal Maturation Value (VMV), and vaginal biopsy. <b><i>Results:</i></b> Seventy-one women were included, 48 completed the study and provided adequate samples for analysis (CO₂L [21 patients], RF [15 patients], and CT [12 patients]). GSM symptoms, I-QOL, and VHI significantly improved after all proposed treatments, with no significant differences between them. VMV did not change after any treatment; however, only 22.9% of the patients presented with cytological atrophy before treatment. Histological vaginal atrophy was identified in 6 (12.5%) pretreated vaginal samples. After the intervention, all histological parameters were normalized, no tissue damage was observed, and no major clinical complications were observed. <b><i>Conclusion:</i></b> CO₂L and RF seem to be good alternatives to CT for GSM treatment, with no tissue damage.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"414-421"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141422365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally Invasive Semiconductor Laser Surgery Combined with 5-ALA Photodynamic Therapy for a Chronic Hyperplastic Candidiasis Patient Who Is Ineffective to Antifungal Therapy.","authors":"Feng Wang, Gang Zhou, Jing Zhang","doi":"10.1089/photob.2023.0174","DOIUrl":"10.1089/photob.2023.0174","url":null,"abstract":"<p><p><b><i>Background:</i></b> Chronic hyperplastic candidiasis (CHC) is a chronic oral mucosal infection caused by Candida, which has potential for malignant transformation. Diagnosing CHC can be challenging due to its various manifestations. In addition, fungal treatments often prove to be ineffective, highlighting the urgent need for a new safe and efficient treatment approach. Given the potential of CHC to transform into malignancy, it is crucial to emphasize dynamic monitoring and follow-up after treatment. <b><i>Objective:</i></b> We attempted to investigate the effect of semiconductor laser pretreatment combined with 5-amino-levulinic acid (5-ALA) photodynamic therapy (PDT) for CHC. <b><i>Methods:</i></b> We presented the successful treatment of CHC with mild dysplasia in a 30-year-old man using semiconductor laser and 5-ALA PDT after antifungal therapy proved ineffective. Toluidine blue staining, autofluorescence imaging, and DNA image cytometry were combined to dynamically monitor the progress of the disease. <b><i>Results:</i></b> We have obtained positive outcomes with the use of laser combined with PDT treatment. The patients experienced only mild adverse reactions after the treatment, and there was no indication of recurrence or malignant transformation during the subsequent follow-up period, as observed through various auxiliary examinations. <b><i>Conclusions:</i></b> This case report suggests that semiconductor laser surgery combined with PDT could be a promising treatment option for patients with CHC who do not respond to antifungal therapy. In addition, the use of combined noninvasive examinations might provide a more accurate assessment of malignant transformation in patients with CHC.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"428-433"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140893010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Response to</i>: Photobiomodulation in the Treatment of Dysgeusia in Patients with Long COVID: Comment.","authors":"Hinpetch Daungsupawong, Viroj Wiwanitkit","doi":"10.1089/pho.2024.0040","DOIUrl":"10.1089/pho.2024.0040","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"437"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Application of PBM Therapy in Patients Subjected to Oral GVHD: A Review.","authors":"Dongqi Liu, Xiao Luo, Yin Jing, Tingting Wu, Fangchun Chen","doi":"10.1089/pho.2023.0153","DOIUrl":"10.1089/pho.2023.0153","url":null,"abstract":"<p><p><b><i>Background:</i></b> Oral graft-versus-host disease (GVHD) is characterized by mucosal lesions, salivary gland dysfunction etc., accompanied by pain and oral dysfunction. The efficacy of photobiomodulation (PBM) in managing pain and inflammation has been demonstrated. PBM has been applied in oral GVHD and is regarded as a potent adjunctive therapy. <b><i>Objective:</i></b> To review the application of PBM for oral GVHD and summarize its biological mechanisms and recommended parameters. <b><i>Materials and Methods:</i></b> The article provides an overview of the therapeutic effects of PBM in oral GVHD cases. It analyzes the biological mechanisms from different aspects and explores the potential prospects of PBM, and appropriate parameters and frequency for GVHD are recommended. <b><i>Conclusions:</i></b> The efficacy of PBM in oral GVHD has been demonstrated through symptom alleviation and function improvement. It is recommended as an adjuvant therapy for oral GVHD. However, further research is required to explore optimal devices, parameters, and potential complications associated with using PBM in oral GVHD.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"439-448"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141433680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Root Regeneration with Photobiomodulation of an Upper Lateral Incisor Associated with Root Resorption Due to an Impacted Maxillary Canine: A Case Report.","authors":"Yax Cuellar, Sergio Andrés Velásquez, Angela Domínguez","doi":"10.1089/photob.2023.0150","DOIUrl":"10.1089/photob.2023.0150","url":null,"abstract":"<p><p><b><i>Objective:</i></b> To present a case report of maxillary lateral incisor root regeneration after severe root resorption, treated with photobiomodulation (PBM). <b><i>Background:</i></b> Impacted maxillary canines often come with the risk of maxillary lateral incisor root resorption, which is widely recognized as the predominant adverse effect in these situations. This progressive process of root resorption is currently irreversible, with no known way to reverse it. <b><i>Materials and methods:</i></b> A male patient was 14 years old. Radiographically it was observed that canine 23 is impacting against the root of 22 producing signs of root resorption and having a less than 1:1 crown-to-root ratio with mobility grade 1. From the beginning of the treatment, PBM-assisted orthodontics was proposed. To address the patient's dental concerns, the treatment plan outlined the extraction of the deciduous upper left canine tooth leaving the lateral as long as possible in the mouth. During each appointment, PBM was applied with a diode laser. The wavelength was 810 nm, Ap = 0.2 W, 4.4 J, 22 sec every 21 days, 13 applications in total (57.2J), with a 400 μm inactive surgical tip, in a scanning movement, 1 mm from the mucosa while moving following the vestibular surface of the upper left lateral and canine roots. <b><i>Results:</i></b> After 12 months, the 22 had root neoformation and complete closure of the apex with vitality. <b><i>Conclusions:</i></b> PBM with an 810 nm diode laser in this clinical case promoted root regeneration of an upper lateral incisor, with severe root resorption, owing to an impacted maxillary canine while still vital.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"422-427"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140892986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}