Photobiomodulation, photomedicine, and laser surgery最新文献

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The Effectiveness of Three Different Irrigant Activation Methods in the Elimination of Enterococcus faecalis from Root Canals. 三种不同灌洗剂活化方法在消除根管中粪肠球菌方面的效果。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-10-01 Epub Date: 2024-07-15 DOI: 10.1089/pho.2023.0189
Ozgur Genc Sen, Ali Erdemir
{"title":"The Effectiveness of Three Different Irrigant Activation Methods in the Elimination of <i>Enterococcus faecalis</i> from Root Canals.","authors":"Ozgur Genc Sen, Ali Erdemir","doi":"10.1089/pho.2023.0189","DOIUrl":"10.1089/pho.2023.0189","url":null,"abstract":"<p><p><b><i>Background and Objective:</i></b> Eliminating intracanal <i>Enterococcus faecalis</i> (<i>E. faecalis</i>) is challenging because of its ability to penetrate deep dentinal tubules and its high resistance to many chemicals. This study evaluated the effectiveness of conventional needle irrigation and three different irrigant activation methods in reducing <i>E. faecalis</i>. <b><i>Methods:</i></b> The root canals of extracted teeth were shaped, contaminated with <i>E. faecalis</i>, and incubated for three weeks. They were randomly allocated to four experimental groups of 15 teeth each according to the final irrigation method: group 1, conventional needle irrigation; group 2, passive ultrasonic (PU) irrigation; group 3, XP-endo Finisher (XPF); and group 4, laser-activated (LA) irrigation. Bacterial samples were taken and cultured before and after these final irrigation procedures. The colony-forming units were counted, and the bacterial reduction percentages of each group were calculated. The Kruskal-Wallis and Dunnet tests were used for statistical analysis. <b><i>Results:</i></b> All irrigant activation methods were significantly more effective than conventional needle irrigation. Although the LA group generated more negative samples than PU, there was no statistically significant difference between the LA and PU groups. LA was significantly more effective than the XPF, whereas PU and XPF were statistically similar. <b><i>Conclusions:</i></b> Within the limitations of this study, the final irrigation with LA and PU showed the best reductive effect on <i>E. faecalis</i> colonies. Considering that the LA group had more negative samples, it may be chosen as an alternative to enhance root canal disinfection, especially in difficult cases.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"628-633"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound-Guided Nd:YAG Laser Intervention in the Orofacial Region: Report of a Case of Multi-Focal Venous Malformation. 超声引导下的 Nd:YAG 激光口面部介入治疗:多灶性静脉畸形病例报告。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-10-01 Epub Date: 2024-08-21 DOI: 10.1089/photob.2024.0012
Jingchen Jia, Mingzhu Feng, Ping Wang, Jing Lv, Wenbin Wang, Bin Ma, Hongshi Li
{"title":"Ultrasound-Guided Nd:YAG Laser Intervention in the Orofacial Region: Report of a Case of Multi-Focal Venous Malformation.","authors":"Jingchen Jia, Mingzhu Feng, Ping Wang, Jing Lv, Wenbin Wang, Bin Ma, Hongshi Li","doi":"10.1089/photob.2024.0012","DOIUrl":"10.1089/photob.2024.0012","url":null,"abstract":"<p><p>Venous malformation is acongenital vascular system structure malformation caused by abnormal vascular endothelial cell morphology, which can occur in any tissue or organ of the oral and maxillofacial region. Laser treatment is currently a commonly used minimally invasive treatment. In this case, the patient with congenital multiple venous malformation was treated with Nd:YAG laser for the visible submucosal part, and the subcutaneous part under the chin tip was treated with ultrasound. The chin tip was treated with ultrasound guided by the chair to achieve the purpose of minimally invasive laser treatment. In this case's diagnosis and treatment process, we hope to provide a new idea for laser treatment of oromaxillofacial vein malformations.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"653-659"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142019983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Photobiomodulation Literature Watch November 2023. 2023 年 11 月光生物调制文献观察。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 Epub Date: 2024-08-09 DOI: 10.1089/photob.2024.0086
James D Carroll
{"title":"Photobiomodulation Literature Watch November 2023.","authors":"James D Carroll","doi":"10.1089/photob.2024.0086","DOIUrl":"10.1089/photob.2024.0086","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"604-607"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Safe and Effective Profile of Using the 1340 nm Wavelength in Conjunction with Other Therapeutic Modalities for Skin Rejuvenation. A Case Series. 将 1340 nm 波长与其他治疗方式结合使用以实现皮肤年轻化的安全有效概况。病例系列。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 Epub Date: 2024-08-16 DOI: 10.1089/photob.2024.0051
Bianca Diffidenti, Alessandra Comito, Irene Fusco, Tiziano Zingoni
{"title":"The Safe and Effective Profile of Using the 1340 nm Wavelength in Conjunction with Other Therapeutic Modalities for Skin Rejuvenation. A Case Series.","authors":"Bianca Diffidenti, Alessandra Comito, Irene Fusco, Tiziano Zingoni","doi":"10.1089/photob.2024.0051","DOIUrl":"10.1089/photob.2024.0051","url":null,"abstract":"<p><p><b><i>Objective:</i></b> This study provided clinical findings supporting the use of combination techniques/products and Nd:YAP 1340 nm fractional laser therapy, for soft-tissue augmentation in light- and darker-skin phototypes. <b><i>Background:</i></b> The face's aging process is complex and involves skin alterations, connective tissues, bone, and fat layers of the face. <b><i>Methods:</i></b> A total of 17 female patients were treated for wrinkles and for scars with the use of Nd:YAP 1340 nm fractional laser combined with other cosmetic therapies. The mean of 4.6(±1.9) laser treatment sessions every 1 month were performed. The combined therapy was administered every 3 months during the total course of the laser treatments. <b><i>Results:</i></b> The total mean improvement was 3.64(±0.49). Clinical images showed a visible aesthetic improvement. No adverse events have been reported. <b><i>Conclusion:</i></b> The combination therapies used have shown promise in maintaining safety and tolerability while improving patient results for the management of skin aging.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"593-597"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141989867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative Investigation of Photobiomodulation in Diabetes-Impaired Alveolar Bone Healing: A Histomorphometrical and Molecular Study. 光生物调节在糖尿病受损牙槽骨愈合中的比较研究:组织形态计量学和分子研究
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 DOI: 10.1089/photob.2023.0170
Zohreh Dalirsani, Mina Davaji, Hamideh Salari Sedigh, Sara Hosseinian, Esmail Ranjbar, Afshin Yaqoubi, Kioumars Maraghe Moghaddam, Reyhaneh Shafieian
{"title":"Comparative Investigation of Photobiomodulation in Diabetes-Impaired Alveolar Bone Healing: A Histomorphometrical and Molecular Study.","authors":"Zohreh Dalirsani, Mina Davaji, Hamideh Salari Sedigh, Sara Hosseinian, Esmail Ranjbar, Afshin Yaqoubi, Kioumars Maraghe Moghaddam, Reyhaneh Shafieian","doi":"10.1089/photob.2023.0170","DOIUrl":"https://doi.org/10.1089/photob.2023.0170","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Diabetes mellitus is increasing worldwide. Photobiomodulation (PBM) is proposed as a therapeutic method in various medical concerns. This study aimed to compare the effects of PBM at the wavelengths of 660, 808, or 660 + 808 nm on alveolar bone healing in diabetic rats. <b><i>Methods:</i></b> Bilateral maxillary first molars were extracted from diabetic Wistar rats (<i>n</i> = 36). Right-sided sockets were treated by an In-Ga-Al-P laser at 660 nm (7.2 J/cm<sup>2</sup>, 24 s; DM660), Ga-Al-As laser at 808 nm (7 J/cm<sup>2</sup>, 14 s; DM808), or a combination of these two sets (DM-dual) (<i>n</i> = 12). Left sides served as controls. On days 7 or 14, specimens were assigned for histomorphometric or real-time PCR analysis of runt-related transcription factor 2, osteocalcin, collagen I, and vascular endothelial growth factor expression. <b><i>Results:</i></b> Irradiated sockets of groups DM-808 and DM-dual showed a significant increase in bone tissue and blood vessel establishment as compared to DM-660. Further, group DM-dual exhibited the least amount of fibrotic tissue as compared to the other groups. <b><i>Conclusions:</i></b> Within our study limits, the present experiment suggested PBM at 808 nm, alone or combined with 660 nm irradiation, could promote alveolar bone healing, along with minimal fibrosis induction, in diabetic rats.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"42 9","pages":"577-584"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Photobiomodulation Associated with Platelet-Rich Plasma in Acute Rheumatoid Arthritis Induced in Female Wistar Rats' Knee. 光生物调节与富血小板血浆对雌性 Wistar 大鼠膝关节急性类风湿性关节炎的影响
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 Epub Date: 2024-07-29 DOI: 10.1089/pho.2024.0060
Bruna Silva Gomes, Amanda Bezerra Gonçalves, Sabrina Zanchetta Lanza, Marcelo Augusto Marretto Esquisatto, Fernando Russo Costa do Bomfim, Gaspar de Jesus Lopes Filho
{"title":"Effects of Photobiomodulation Associated with Platelet-Rich Plasma in Acute Rheumatoid Arthritis Induced in Female Wistar Rats' Knee.","authors":"Bruna Silva Gomes, Amanda Bezerra Gonçalves, Sabrina Zanchetta Lanza, Marcelo Augusto Marretto Esquisatto, Fernando Russo Costa do Bomfim, Gaspar de Jesus Lopes Filho","doi":"10.1089/pho.2024.0060","DOIUrl":"10.1089/pho.2024.0060","url":null,"abstract":"<p><p><b><i>Objective:</i></b> Rheumatoid arthritis causes inflammation, pain, and joint degradation, necessitating treatment with anti-inflammatory drugs and corticosteroids, posing various challenges. We aimed to evaluate the effects of photobiomodulation (PBM) at two different doses associated to platelet-rich plasma (PRP) in an in vivo model of induced acute arthritis in Wistar rats' knee. <b><i>Methods:</i></b> Eighty-four Wistar rats were assigned into seven groups, including animals treated with PBM and/or PRP. On day 0, arthritis was induced in sham and treated groups through the intra-articular injection of zymosan (200 μg). Twenty-four hours after induction, the PBM groups were treated with an AsGaAl laser, whereas the PRP-treated groups received intra-articular injections with a concentration of 8 × 10<sup>5</sup> platelets obtained from another four animals. After 3 days, the animals were euthanized, and the interleukin (IL)-6 and complement C3 gene and protein expression levels were analyzed. Statistical analysis was performed using the mean ± SD with analysis of variance and Tukey's posttest, with a significance level set at 5% (<i>p</i> < 0.05). <b><i>Results:</i></b> Synovial inflammation decreased in PBM-treated groups; however, PRP alone showed no significant difference. Gene expression analysis revealed a significant difference in IL-6 and C3 levels in the PBM and PBM+PRP-treated groups. Meanwhile, the PRP alone group exhibited significance for IL-6. Moreover, the PBM and PBM+PRP-treated groups showed a significant difference in C3 protein expression levels, whereas the PRP alone group showed no difference. <b><i>Conclusion:</i></b> The increase in cellular activity in the synovial membrane and the decrease protein expression levels are owing to the reduction in proinflammatory mediators following PBM therapy.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"585-592"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141790713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Local Anesthetics on Tissue Penetration Using Diode Lasers in Intraoral Tissues. 局部麻醉剂对口腔内组织使用二极管激光穿透的影响
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 Epub Date: 2024-09-04 DOI: 10.1089/photob.2024.0005
Georgios Romanos, Jamie Wu, Ed Gheorghe Roibu, Yun Zhang, Rafael Delgado-Ruiz
{"title":"Effects of Local Anesthetics on Tissue Penetration Using Diode Lasers in Intraoral Tissues.","authors":"Georgios Romanos, Jamie Wu, Ed Gheorghe Roibu, Yun Zhang, Rafael Delgado-Ruiz","doi":"10.1089/photob.2024.0005","DOIUrl":"10.1089/photob.2024.0005","url":null,"abstract":"<p><p><b><i>Objective:</i></b> The purpose of this study was to demonstrate heat transfer within oral soft tissues using different lasers under the effect of local anesthetics (LA). <b><i>Methods:</i></b> Bovine tongue slices were placed in between two glass slides and at a distance from a thermographic camera. In total, 2-cm-long 240 incisions were made along the surface of the tissue parallel to glass slides and the camera capture field. Incisions were performed using 445-nm and infrared (IR) lasers (970 nm and 980 nm on a continuous wave at 2 W) with 320 µm-initiated (concentrated energy at the tip provided by a blue articulated paper and laser irradiation) and noninitiated (defused energy) fiber (30-sec irradiation period). LA was injected into the specimens before irradiation. The temperature changes in °C (ΔT) and vertical and lateral heat transfer (in mm) were recorded at 10-sec intervals for 30 sec, using thermographic images. The amount of lateral and vertical heat transfer was measured. A repeated analysis of variance statistical comparison test was used to analyze differences between the lateral (width) and the vertical (height) heat transfer for initiated and noninitiated lasers and different lasers. <b><i>Results:</i></b> The maximum ΔT in °C utilizing initiated tips of 970, 980, or 445 nm were 11.82 ± 3.46, 7.66 ± 3.24, and 18.94 ± 7.01 and using noninitiated tips were 8.27 ± 1.69, 8.87 ± 2.40, and 12.31 ± 8.65, respectively. Heat transfers (height/width) for initiated were 40.65 ± 10.40/90.65 ± 10.77 mm, 41.50 ± 11.83/83.95 ± 11.20 mm, and 33.70 ± 9.10/95.10 ± 11.17 mm and for noninitiated lasers were 52.95 ± 6.89/96.10 ± 11.17 mm, 47.75 ± 7.41/93.75 ± 14.96 mm, and 31.35 ± 11.40/75.20 ± 19.68 mm, respectively. A statistically significant difference was found between all lasers (<i>p</i> < 0.05) for initiated and noninitiated lasers (except for 970/980 nm for noninitiated lasers). Lower penetration depth (<i>p</i> < 0.05) at 445-nm diode and greater lateral heat spreading (<i>p</i> < 0.05) were identified under LA especially utilizing noninitiated tips without significant difference in IR lasers. <b><i>Conclusions:</i></b> LA might negatively influence soft tissues creating scattering when noninitiated tips are used and IR diode laser technology.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"598-603"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142127780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transient Selective Neural Inhibition via PBM. 通过 PBM 实现瞬时选择性神经抑制
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 Epub Date: 2024-08-19 DOI: 10.1089/photob.2024.0065
Michael W Jenkins, Andrew Buzza, Aaron C Skubal, Michael A Moffitt, Juanita J Anders
{"title":"Transient Selective Neural Inhibition via PBM.","authors":"Michael W Jenkins, Andrew Buzza, Aaron C Skubal, Michael A Moffitt, Juanita J Anders","doi":"10.1089/photob.2024.0065","DOIUrl":"10.1089/photob.2024.0065","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"574-576"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142001607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for Photobiomodulation, Photomedicine, and Laser Surgery. 罗莎琳德-富兰克林学会自豪地宣布 2023 年度光生物调节、光医学和激光手术奖获得者。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-09-01 DOI: 10.1089/photob.2024.15876.rfs2023
Carla Dias de Oliveira
{"title":"Rosalind Franklin Society Proudly Announces the 2023 Award Recipient for <i>Photobiomodulation, Photomedicine, and Laser Surgery</i>.","authors":"Carla Dias de Oliveira","doi":"10.1089/photob.2024.15876.rfs2023","DOIUrl":"https://doi.org/10.1089/photob.2024.15876.rfs2023","url":null,"abstract":"","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":"42 9","pages":"573"},"PeriodicalIF":1.8,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Rose Bengal-Mediated Antimicrobial Photodynamic Therapy as an Adjunct to Scaling and Root Planing on Clinical and Microbiological Parameters in the Management of Chronic Periodontitis: A Single-Blinded, Randomized Controlled Clinical Trial. 玫瑰红介导的抗菌光动力疗法作为洗牙和根面平整术的辅助疗法对治疗慢性牙周炎的临床和微生物参数的疗效:单盲随机对照临床试验》。
IF 1.8
Photobiomodulation, photomedicine, and laser surgery Pub Date : 2024-08-01 Epub Date: 2024-07-15 DOI: 10.1089/pho.2024.0037
Nivedha Nedumaran, Arvina Rajasekar
{"title":"Efficacy of Rose Bengal-Mediated Antimicrobial Photodynamic Therapy as an Adjunct to Scaling and Root Planing on Clinical and Microbiological Parameters in the Management of Chronic Periodontitis: A Single-Blinded, Randomized Controlled Clinical Trial.","authors":"Nivedha Nedumaran, Arvina Rajasekar","doi":"10.1089/pho.2024.0037","DOIUrl":"10.1089/pho.2024.0037","url":null,"abstract":"<p><p><b><i>Aim:</i></b> The study aims to assess the efficacy of rose bengal (RB)-mediated antimicrobial photodynamic therapy (a-PDT) as an adjunct to scaling and root planing in the management of chronic periodontitis patients in terms of clinical parameters like gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL), and microbiological parameters like total microbial count, total red complex organism count, <i>Porphyromonas gingivalis</i> count, <i>Treponema denticola</i> count, and <i>Tannerella forsythia</i> count. <b><i>Materials and Methods:</i></b> In this randomized controlled clinical trial, a total of 30 patients were recruited who met the inclusion criteria. The participants were randomly allocated into group A with scaling and root planning (SRP) alone and group B with SRP + a-PDT. The clinical and microbiological parameters were measured at baseline and at 3-month follow-up. Intergroup and intragroup comparisons were performed using independent <i>t</i> test and paired <i>t</i> test, respectively. Value of <i>p</i> < 0.05 was considered as statistically significant. <b><i>Results:</i></b> At 3-month follow-up, group B treated with SRP + a-PDT showed statistically significant reduction in GI (0.58 ± 0.20) and PPD (1.81 ± 0.32 mm), gain in CAL (0.73 ± 0.04 mm), and reduction in total microbial count [2.80 ± 0.08 × 10<sup>4</sup> colony forming unit (CFU)], total red complex count (0.29 ± 0.14 × 10<sup>2</sup> CFU), <i>P. gingivalis</i> count (0.43 ± 0.13 × 10<sup>2</sup> CFU), <i>T. denticola</i> count (0.61 ± 0.04 × 10<sup>2</sup> CFU), and <i>T. forsythia</i> count (0.59 ± 0.04 × 10<sup>2</sup> CFU) as compared with group A (<i>p</i> < 0.05). <b><i>Conclusion:</i></b> RB-mediated a-PDT as an adjunct to SRP was significantly more effective in improving GI, PPD, and CAL and in reducing microbial count as compared with SRP alone in the management of chronic periodontitis.</p>","PeriodicalId":94169,"journal":{"name":"Photobiomodulation, photomedicine, and laser surgery","volume":" ","pages":"561-567"},"PeriodicalIF":1.8,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141617864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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