Obesity (Silver Spring, Md.)最新文献_第2页

Response to "Development and Validation of the Food Noise Questionnaire". 对“食物噪音问卷的编制及验证”的回应。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-20 DOI: 10.1002/oby.24349

Daisuke Hayashi, Caitlyn Edwards, Jennifer A Emond, Diane Gilbert-Diamond, Ann M Rogers, Andrea Rigby, Melissa Butt, Travis D Masterson

引用次数: 0

Gap of women leadership in global obesity research. 女性在全球肥胖研究中的领导地位差距。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-18 DOI: 10.1002/oby.24324

Xiangxin Kong, Feifei Guo, Nan Hu, Wei Yang, Bosheng Ma, Furong Zhu, Yuan Yuan, Jia Xiao, Yixing Ren

{"title":"Gap of women leadership in global obesity research.","authors":"Xiangxin Kong, Feifei Guo, Nan Hu, Wei Yang, Bosheng Ma, Furong Zhu, Yuan Yuan, Jia Xiao, Yixing Ren","doi":"10.1002/oby.24324","DOIUrl":"https://doi.org/10.1002/oby.24324","url":null,"abstract":"Objective: This study aims to evaluate and summarize the current state of gender equality for female scientists in obesity research.Methods: We conducted a comprehensive analysis of governmental funding, high-impact publications/citations, and awards received by female and male scientists engaged in obesity research worldwide. Median citations were compared by sex and year, with group differences assessed using the nonparametric Mann-Whitney U test.Results: Our findings reveal a concerning difference: In most representative countries, a higher proportion of male principal investigators received grant support, with Japan exhibiting the most pronounced gender bias. In highly cited obesity papers, female corresponding authors constituted only 33%, with Japan having the lowest representation at a mere 5%, whereas the Netherlands approached near-equal representation (49%). Furthermore, highly cited obesity papers authored by women generally received fewer citations than those by men across most analyzed years and countries. However, a positive trend emerged in awards: the European Association for the Study of Obesity and the Association for the Study of Obesity recognized female scientists at a higher rate than male scientists.Conclusions: These findings highlight a complex landscape. Although female scientists have gained increased support and recognition in several countries, significant gender inequality persists in obesity research.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144661480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Grip strength: are some adiposity phenotypes more detrimental than others? A Mendelian randomization study. 握力：某些肥胖表型比其他肥胖表型更有害吗？孟德尔随机化研究。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-17 DOI: 10.1002/oby.24339

Amy E Taylor, John Vincent, Dylan M Williams, Rachel Cooper, Snehal M Pinto Pereira

{"title":"Grip strength: are some adiposity phenotypes more detrimental than others? A Mendelian randomization study.","authors":"Amy E Taylor, John Vincent, Dylan M Williams, Rachel Cooper, Snehal M Pinto Pereira","doi":"10.1002/oby.24339","DOIUrl":"https://doi.org/10.1002/oby.24339","url":null,"abstract":"Objective: Our objective was to investigate causal associations of adiposity in different locations and metabolically favorable and unfavorable adiposity (MetFA and MetUFA, respectively) with grip strength.Methods: Observational cross-sectional and Mendelian randomization (MR) (sex combined and stratified) analysis within UK Biobank (N ≤ 340,258) was used to assess the relationships of visceral, abdominal subcutaneous, and gluteofemoral adipose tissue, anterior and posterior thigh muscle fat infiltration (ATMFI and PTMFI, respectively), body fat (BF) percentage, MetFA, and MetUFA with grip strength.Results: In inverse variance weighted MR analysis, SD increases in BF, MetFA, and ATMFI were associated with lower grip strength by the following: -0.10 SD (95% CI: -0.16 to -0.04), -0.31 SD (95% CI: -0.45 to -0.18), and -0.05 SD (95% CI: -0.09 to -0.01), respectively. PTMFI associations aligned with ATMFI. Observational analyses were consistent for BF and ATMFI/PTMFI, but weighted median/mode MR corroborated findings for MetFA and ATMFI/PTMFI only. Higher visceral adipose tissue was associated with lower grip strength in observational analyses only. Associations for higher abdominal subcutaneous adipose tissue were inconsistent: Observational analyses suggested weaker grip; MR analyses suggested stronger grip, particularly in female individuals. There was no strong evidence in MR for associations with MetUFA or gluteofemoral adipose tissue.Conclusions: Targeting fat infiltration in muscle may improve muscle function. MetFA appears to negatively impact muscle strength, requiring further investigation into underlying mechanisms.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trends in prevalence of health and cardiovascular risk factors based on Life's Essential 8 among US adults, 2007-2020. 2007-2020年美国成年人基于生命要素8的健康和心血管风险因素流行趋势

Obesity (Silver Spring, Md.) Pub Date : 2025-07-16 DOI: 10.1002/oby.24334

Lixia Zhang, Yun Shen, Yibo Tang, Yihui Wu, Danqing Chen, Zhaoxia Liang, Gang Hu

{"title":"Trends in prevalence of health and cardiovascular risk factors based on Life's Essential 8 among US adults, 2007-2020.","authors":"Lixia Zhang, Yun Shen, Yibo Tang, Yihui Wu, Danqing Chen, Zhaoxia Liang, Gang Hu","doi":"10.1002/oby.24334","DOIUrl":"https://doi.org/10.1002/oby.24334","url":null,"abstract":"Objective: This study aimed to determine trends in the prevalence of health factors and risk factors based on Life's Essential 8 (LE8) among US adults.Methods: The present study included 26,548 adults from the National Health and Nutrition Examination Survey in 2007-2008 to 2017-2020. Crude weighted prevalence and 95% CI values of individual risk and health factors based on LE8 were estimated by cycle, and their trends were assessed in logistic regression models.Results: From 2007-2008 to 2017-2020, the prevalence of lack of physical activity (27.2% to 22.5%), current smoking (21.2% to 15.9%), less sleep time (37.1% to 22.7%), and hyperlipidemia (55.8% to 50.8%) decreased, and obesity (33.9% to 43.3%) and hypertension (31.5% to 34.6%) increased, whereas unhealthy diet and diabetes remained stable. There were significant increases in the prevalence of sufficient physical activity (59.7% to 66.7%), never smoking (50.3% to 55.5%), enough sleep time (56.8% to 60.6%), and normal blood lipids (30.2% to 35.6%) and significant decreases in the prevalence of normal weight (30.8% to 25.7%), normal blood glucose (71.5% to 64.8%), and normal blood pressure (61.3% to 58.7%).Conclusions: This study found improvement in physical activity, smoking, sleep health, and blood lipids and worsening of weight, blood glucose, and blood pressure among US adults from 2007-2008 to 2017-2020.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial. 在超重和肥胖成人隔日禁食期间补充磷虾油的益处：一项随机试验。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-16 DOI: 10.1002/oby.24354

Mansour Alblaji, Stuart R Gray, Taibah Almesbehi, Douglas J Morrison, Dalia Malkova

{"title":"Benefits of Krill Oil Supplementation During Alternate-Day Fasting in Adults With Overweight and Obesity: A Randomized Trial.","authors":"Mansour Alblaji, Stuart R Gray, Taibah Almesbehi, Douglas J Morrison, Dalia Malkova","doi":"10.1002/oby.24354","DOIUrl":"https://doi.org/10.1002/oby.24354","url":null,"abstract":"Objective: To investigate the effect of krill oil (KO) supplementation during alternate-day fasting (ADF) on body composition and muscle function in healthy adults with overweight.Methods: In a randomized trial, during the 8-week ADF, participants consumed four capsules per day containing krill oil (KO group) or vegetable oil (placebo group). Each capsule of KO contained 191 mg EPA, 94 mg DHA, 78 mg choline, and 100 mcg astaxanthin. Body mass, fat-free mass (FFM), and handgrip strength (HGS) were measured before and after the intervention. Data were analyzed using ANOVA.Results: The study was completed by 41 (25 women and 16 men) participants (age: 39 ± 10 years, BMI: 31.1 ± 4.2 kg/m2). Body weight reduction was not different (p > 0.05) between groups (KO, -4.6 ± 1.4 kg; Placebo, -4.5 ± 1.9 kg). The KO group had no change (p > 0.05) in FFM (-0.2 ± 0.9 kg) or HGS (-0.2 ± 0.5 kg). The placebo group experienced a reduction (p < 0.05) in FFM (-1.2 ± 2.0 kg) and HGS (-0.9 ± 0.7 kg). Changes in FFM and HGS were different (p < 0.05) between groups.Conclusions: KO supplementation during body weight loss attenuates the decline in FFM and muscle strength.Trial registration: ClinicalTrials.gov Identifier (NCT06001632).","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synergistic association of estradiol and body roundness index with accelerated biological aging in male individuals. 雌二醇和身体圆度指数与男性个体加速生物衰老的协同关联。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-16 DOI: 10.1002/oby.24326

Fan Dong, Yi Ma, Xiang-Feng Chen

{"title":"Synergistic association of estradiol and body roundness index with accelerated biological aging in male individuals.","authors":"Fan Dong, Yi Ma, Xiang-Feng Chen","doi":"10.1002/oby.24326","DOIUrl":"https://doi.org/10.1002/oby.24326","url":null,"abstract":"Objective: The objective of this study was to investigate the relationship of estradiol or body roundness index (BRI), respectively, or the coexistence of their changes with accelerated biological aging in male individuals.Methods: A cross-sectional study with 1818 male individuals aged 20 to 79 years who participated in the National Health and Nutrition Examination Survey 2015-2016 was conducted, in which positive phenotypic age acceleration value was defined as the occurrence of accelerated biological aging. Weighted multivariate logistic regression models were established to evaluate the independent and joint associations of estradiol and BRI with male accelerated biological aging. Restricted cubic spline models were used to explore whether a nonlinear relationship existed.Results: An independent association of either serum estradiol or BRI with male accelerated biological aging was significantly shown after adjusting for important covariates. For BRI, such an association was nonlinear, but estradiol did not exhibit a similar nonlinear correlation. Moreover, the coexistence of a high level of serum estradiol and a high level of BRI obviously strengthens such an association in adjusted models, suggesting the cooperative impact of estradiol with BRI.Conclusions: Both serum estradiol and BRI are significantly associated with accelerated biological aging in male individuals. Integrating high estradiol with high BRI might noticeably reinforce this association.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations of BMI, sleep quality, and sleep duration trajectories with new-onset diabetes mellitus in the elderly. 体重指数、睡眠质量和睡眠时间轨迹与老年人新发糖尿病的关系

Obesity (Silver Spring, Md.) Pub Date : 2025-07-16 DOI: 10.1002/oby.24338

Shanshan Li, Boyi Yang, Shasha Shang, Wei Jiang

{"title":"Associations of BMI, sleep quality, and sleep duration trajectories with new-onset diabetes mellitus in the elderly.","authors":"Shanshan Li, Boyi Yang, Shasha Shang, Wei Jiang","doi":"10.1002/oby.24338","DOIUrl":"https://doi.org/10.1002/oby.24338","url":null,"abstract":"Objective: Our objective was to investigate the relationships between BMI, sleep quality, and sleep duration trajectories and new-onset diabetes mellitus (NODM) in the elderly.Methods: We analyzed 2648 diabetes-free participants aged ≥60 years from the Chinese Longitudinal Healthy Longevity Survey (CLHLS) in 2014. Using Cox proportional hazards models, we examined the associations of BMI, self-reported sleep quality, and sleep duration trajectories (categorized as persistent short, persistent normal, persistent long, low-increasing, normal-decreasing, normal-increasing, and long-decreasing) with NODM risk over 4 years. Diabetes diagnosis was self-reported.Results: Over 4 years, 94 participants developed NODM. Obesity was associated with the highest risk (adjusted hazard ratio [HR] 2.247 [CI: 1.212-4.168]). Compared with individuals with good sleep quality, those with poor sleep quality showed an increased risk of NODM, but this association was not statistically significant (HR 1.570 [0.903-2.731]). Additionally, persistent short, normal-decreasing, and long-decreasing sleep trajectories were associated with elevated NODM risk (adjusted HR values 11.662 [CI: 1.565-86.896], 8.403 [CI: 1.023-69.010], and 9.474 [CI: 1.269-70.700]).Conclusions: BMI, sleep quality, and sleep duration trajectories are associated with NODM risk. Individuals with higher BMI values, poor sleep quality, or persistent short or decreasing sleep duration may be at higher risk for NODM, warranting further attention.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144651670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Clinical Obesity in US Adults, 2017-2020. 2017-2020年美国成年人临床肥胖患病率

Obesity (Silver Spring, Md.) Pub Date : 2025-07-14 DOI: 10.1002/oby.24352

Yun Shen, Gang Hu

{"title":"Prevalence of Clinical Obesity in US Adults, 2017-2020.","authors":"Yun Shen, Gang Hu","doi":"10.1002/oby.24352","DOIUrl":"https://doi.org/10.1002/oby.24352","url":null,"abstract":"Objective: We aimed to estimate the prevalence of clinical obesity among US adults using the newly proposed definition and evaluate differences across demographic subgroups.Methods: This cross-sectional study analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2017-2020 cycle. The analysis included 8037 adults aged 20 years or older with complete data. Clinical obesity was defined per the Lancet Diabetes & Endocrinology Commission on the definition and diagnosis of clinical obesity.Results: Among 8037 participants, the overall prevalence of clinical obesity was 9.7% (95% CI, 8.9%-10.5%), with comparable prevalence in males (9.8%) and in females (9.6%). Younger adults (aged 20-39 years) exhibited the highest prevalence (11.9%), followed by those aged 40-59 years (8.2%). Significant racial/ethnic and sex disparities were observed, with Mexican females having the highest prevalence (13.9%), followed by non-Hispanic Black females (13.5%) and non-Hispanic White males (10.6%). The prevalence decreased significantly when the new definition with organ dysfunctions or limitations of daily activities was applied compared with BMI alone.Conclusions: This study provided the first nationally representative estimates of clinical obesity prevalence in US adults based on the new definition.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144639144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Adiposity associations with risk of colorectal cancer: a systematic review. 肥胖与结直肠癌风险的关系：一项系统综述

Obesity (Silver Spring, Md.) Pub Date : 2025-07-13 DOI: 10.1002/oby.24314

Shelby G Ziller, Carrie S Standage-Beier, Uzoamaka E Okwor, D Jean McClelland, Bahar Bakhshi, Dawn K Coletta, Jennifer W Bea

{"title":"Adiposity associations with risk of colorectal cancer: a systematic review.","authors":"Shelby G Ziller, Carrie S Standage-Beier, Uzoamaka E Okwor, D Jean McClelland, Bahar Bakhshi, Dawn K Coletta, Jennifer W Bea","doi":"10.1002/oby.24314","DOIUrl":"https://doi.org/10.1002/oby.24314","url":null,"abstract":"Objective: This systematic review evaluates the relationship between adiposity and incident colorectal cancer (CRC) risk.Methods: MEDLINE, Scopus, Embase, CINAHL, and CENTRAL were searched for articles that met the following criteria: 1) assessed adiposity measures; 2) included incident data for any diagnosed malignant stage of CRC, colon cancer, or rectal cancer; and 3) studied adults aged older than 18 years. Articles were assessed for bias using the National Institutes of Health study quality assessment tools.Results: Fifteen articles across ten studies met the inclusion criteria. Three significant associations were positive, one was negative, and eleven were nonsignificant and positive. Measures varied based on the tool, and these four tools were used to gather body composition measures: bioelectrical impedance, computerized tomography, dual-energy x-ray absorptiometry, and ultrasound. The most used were total body fat mass and percent fat, along with abdominal visceral and subcutaneous adipose tissues. Overall, higher levels of adipose were positively associated with an increased risk of CRC. The strength of associations and significance varied by body composition variable, measurement technique, tumor location, and sex.Conclusions: Standardization is needed to better elucidate the relation between CRC and adiposity to allow for comparisons across papers. Additionally, a balance among precision, accessibility, and cost of measurements must be struck.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144628309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Associations between coexposure to bisphenols mixture and metabolic diseases: based on three statistical models. 共同暴露于双酚混合物与代谢性疾病之间的关系：基于三种统计模型。

Obesity (Silver Spring, Md.) Pub Date : 2025-07-10 DOI: 10.1002/oby.24327

Yaqi Zhu, Keqin Liu, Jinjin Guo, Yuqi Wang, Jixin Yang, Yanwei Su

{"title":"Associations between coexposure to bisphenols mixture and metabolic diseases: based on three statistical models.","authors":"Yaqi Zhu, Keqin Liu, Jinjin Guo, Yuqi Wang, Jixin Yang, Yanwei Su","doi":"10.1002/oby.24327","DOIUrl":"https://doi.org/10.1002/oby.24327","url":null,"abstract":"Introduction: Bisphenol A (BPA) and its substitutes are common environmental endocrine disruptors. We investigated whether coexposure to BPA and its substitutes are associated with metabolic diseases (MDs), the related indicators, and their multimorbidity.Methods: The study included 1409 participants from the National Health and Nutrition Examination Survey (NHANES). Generalized linear regression, Bayesian kernel machine regression, and the weighted quantile sum (WQS) models were used to study the associations between bisphenol concentrations and comprehensive MDs, including their multimorbidity.Results: In the logistic regression model, BPA and bisphenol F were each independently associated with obesity, whereas BPA and bisphenol S (BPS) were each independently associated with multimorbidity. In the Bayesian kernel machine regression analysis, the joint effects of the three chemicals were positively associated with hypertension and obesity, with BPS generating the highest posterior inclusion probability. In the WQS regression analysis, the WQS index demonstrated significant associations with obesity and hypertension, with BPS the highest contributor to both of them.Conclusions: Three statistical methods confirmed that BPA and its substitutes were associated with specific MDs. Our findings indicate that coexposure to bisphenols significantly increases the risk of obesity and hypertension.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144610701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0