Obesity (Silver Spring, Md.)最新文献

From Parallel Practice to Shared Evidence: Korean Traditional Medicine in Obesity Care. 从平行实践到共享证据：韩国传统医学在肥胖治疗中的应用。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-20 DOI: 10.1002/oby.70330

Jong Han Choi, Yu Mi Kang

引用次数: 0

Interdisciplinary Weight Management in a Safety-Net Health System: A Pilot Implementation Study. 安全网卫生系统中的跨学科体重管理：试点实施研究。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-19 DOI: 10.1002/oby.70306

Courtney DeCan, Katie Thure, Nat Pedley, Brett Cervantes, Osbaldo Camargo, Karina Fing Castro, Jacqueline Cabral, Michelle Gallardo, Dailyn Rodriguez Reyes, Alejandra Perez, Stephanie Young, Arash Nafisi, Soma Wali

{"title":"Interdisciplinary Weight Management in a Safety-Net Health System: A Pilot Implementation Study.","authors":"Courtney DeCan, Katie Thure, Nat Pedley, Brett Cervantes, Osbaldo Camargo, Karina Fing Castro, Jacqueline Cabral, Michelle Gallardo, Dailyn Rodriguez Reyes, Alejandra Perez, Stephanie Young, Arash Nafisi, Soma Wali","doi":"10.1002/oby.70306","DOIUrl":"https://doi.org/10.1002/oby.70306","url":null,"abstract":"Objective: Despite the high prevalence of obesity and cardiometabolic diseases in safety-net populations, access to intensive, evidence-based lifestyle interventions and scalable implementation strategies remains limited. This study evaluated the effectiveness, acceptability, and feasibility of an interdisciplinary program in an urban safety-net health system.Methods: This single-center, mixed-methods implementation evaluation assessed LA VIDA, a 6-month interdisciplinary weight management program for medically complex individuals. Outcomes included feasibility, patient engagement, self-rated health, quality of life, physical activity, dietary behaviors, and program satisfaction.Results: Over 2 years, 95 participants completed the program. They were predominantly female (72.6%) and Latino (78.9%), with a mean age of 50 years, median BMI of 39.2 (IQR: 36.9 to 43.7), and 60% having ≥ 3 comorbidities. Median 6-month weight loss was 5.5% (IQR: -2.6% to -9.9%), with significant improvements in quality of life (p = 0.0003), physical health (p < 0.0001), moderate-intensity physical activity (p < 0.001), and dietary behaviors. Participants reported high satisfaction driven by personalized guidance, increased health knowledge, mindfulness, and the supportive group environment.Conclusions: LA VIDA was feasible and acceptable and improved patient-reported behaviors and outcomes in a safety-net setting. These findings support it as an effective model for integrated obesity care that combines lifestyle, behavioral, and pharmacologic treatment in the safety net.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149225562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obesity Increases Cardiovascular Strain During Passive Whole-Body Heat Stress in Middle-Aged Women. 肥胖增加中年妇女被动全身热应激时的心血管负荷。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-16 DOI: 10.1002/oby.70314

Georgia R Davila, Sandra N Fredericks, William E Jennings, Emily A Haskell, Jamie A Cooper, S Tony Wolf

{"title":"Obesity Increases Cardiovascular Strain During Passive Whole-Body Heat Stress in Middle-Aged Women.","authors":"Georgia R Davila, Sandra N Fredericks, William E Jennings, Emily A Haskell, Jamie A Cooper, S Tony Wolf","doi":"10.1002/oby.70314","DOIUrl":"https://doi.org/10.1002/oby.70314","url":null,"abstract":"Objective: Heat-related mortality is greater in middle-aged and older women, compared with age-matched men, and in those with obesity, although the causes are unclear.Methods: Thermoregulatory and cardiovascular responses were assessed in (n = 10 per group) young women (21 ± 2 years), middle-aged women without obesity (-OB; 55 ± 6 years), and middle-aged women with obesity (+OB; 55 ± 4 years) during whole-body heat stress until a change in core temperature (ΔTc) = 1°C. Cutaneous vasodilation (laser-Doppler flowmetry) and whole-body sweat rate (sweat loss/body surface area/time) were measured as indices of thermoregulatory function. Heart rate and blood pressure were measured, and rate pressure product (RPP = heart rate × systolic blood pressure) was calculated as an index of cardiovascular strain.Results: The magnitude of the peak cutaneous vasodilation response was not different among the groups (p ≥ 0.21), but thermosensitivity was higher in Young compared with +OB and -OB (p ≤ 0.03). Although there were no baseline differences in RPP (p ≥ 0.67), end-heating RPP was higher in +OB compared with -OB and Young (p ≤ 0.008). Further, body fat percentage was related to peak RPP (p = 0.03, R2 = 0.24) in middle-aged women.Conclusions: Increased adiposity may contribute to greater cardiovascular risk during extreme heat exposure in middle-aged women.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149208425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Update of Korean Medicine Clinical Practice Guidelines for Obesity Management: An Evidence-Based GRADE Approach. 韩国医学肥胖管理临床实践指南的更新：循证分级方法。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-15 DOI: 10.1002/oby.70242

Soo-Dam Kim, Mi Ju Son, Bo-Young Kim, Mi Mi Ko, Kyung Hwan Jegal, Hojun Kim, Seo-Hyun Park, Koh-Woon Kim, Mi Young Song, Junyoung Jo, Hyungsuk Kim, Woo-Chul Shin, Taeoh Kim, HuiYan Zhao, Changsop Yang, Won-Seok Chung, Sungha Kim

{"title":"Update of Korean Medicine Clinical Practice Guidelines for Obesity Management: An Evidence-Based GRADE Approach.","authors":"Soo-Dam Kim, Mi Ju Son, Bo-Young Kim, Mi Mi Ko, Kyung Hwan Jegal, Hojun Kim, Seo-Hyun Park, Koh-Woon Kim, Mi Young Song, Junyoung Jo, Hyungsuk Kim, Woo-Chul Shin, Taeoh Kim, HuiYan Zhao, Changsop Yang, Won-Seok Chung, Sungha Kim","doi":"10.1002/oby.70242","DOIUrl":"https://doi.org/10.1002/oby.70242","url":null,"abstract":"Objective: Obesity is a major health challenge associated with multiple chronic diseases. Korean traditional medicine (KM) offers diverse therapeutic approaches for obesity management. This study aims to update the Korean Medicine Clinical Practice Guidelines (KMCPGs) by incorporating recent evidence to improve the effectiveness of KM-based obesity care.Methods: The KMCPGs were updated through systematic searches of eight databases for studies published up to December 31, 2022. Evidence quality and recommendation strength were evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework.Results: The updated KMCPGs present 20 clinical recommendations, including 7 for KM monotherapies and 13 for KM combination therapies. The recommendations include herbal medicine (A/high), individualized ephedra-containing prescriptions (GPP), acupuncture (B/low), auricular acupuncture (C/low), electroacupuncture (B/low), pharmacopuncture (B/moderate), TEA (C/low), and 13 combination therapies ranging from grade B to C or GPP. Most recommendations focus on anthropometric outcomes, including body weight, BMI, WC, and body fat-related measures.Conclusions: The update of the KMCPGs underscores the clinical value of KM interventions in obesity management while emphasizing the need for further high-quality studies to strengthen the evidence. Addressing implementation barriers and ensuring regular guideline updates are essential for optimizing clinical application and improving patient outcomes in obesity care.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149198560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-Term Impact of Bariatric Surgery and Dietary Interventions on Weight Loss, Physical Activity, and Food Preferences. 减肥手术和饮食干预对体重减轻、身体活动和食物偏好的长期影响。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-14 DOI: 10.1002/oby.70329

Michael Do, Dana Bliuc, John A Eisman, Jerry R Greenfield, Jacqueline R Center, Malgorzata M Brzozowska

{"title":"Long-Term Impact of Bariatric Surgery and Dietary Interventions on Weight Loss, Physical Activity, and Food Preferences.","authors":"Michael Do, Dana Bliuc, John A Eisman, Jerry R Greenfield, Jacqueline R Center, Malgorzata M Brzozowska","doi":"10.1002/oby.70329","DOIUrl":"https://doi.org/10.1002/oby.70329","url":null,"abstract":"Objective: This study aimed to examine changes in dietary intake, physical activity, appetite, and weight following laparoscopic adjustable gastric banding (LAGB), sleeve gastrectomy (SG), Roux-en-Y gastric bypass (RYGB), and dietary intervention in adults with severe obesity.Methods: This prospective, nonrandomized cohort included 57 adults undergoing LAGB (n = 11), SG (n = 21), RYGB (n = 7), or dietary intervention (Diet; n = 18). Seven assessments over 36 months were analyzed using mixed-effects models.Results: During the first 12 months, energy intake declined across groups (β = -1322 kJ/visit; 95% CI: -2045, -599; p < 0.001), without between-group differences in energy or macronutrient trajectories. Vigorous activity increased following SG relative to Diet (interaction β = +10 min/day/visit; 95% CI: 0.1, 20). During 12-36 months, energy intake increased in Diet (β = +3089 kJ/visit; p < 0.001), whereas surgical groups maintained energy restriction (all interactions p ≤ 0.006). Changes in macronutrients, calcium intake, and physical activity were modest or transient, although protein intake increased after LAGB relative to Diet (interaction β = +8.6 percentage points; p = 0.006). SG produced sustained appetite reduction (p ≤ 0.013). At 36 months, weight remained 25.1%, 26.4%, and 16.9% below baseline following SG, RYGB, and LAGB, respectively.Conclusions: Interventions demonstrated biphasic dietary and behavioral adaptation. Surgical procedures produced durable energy restriction and weight loss despite modest long-term changes in dietary composition and physical activity.Trial registration: ANZCTR: 12613000188730.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149187152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Conventional Cost-Effectiveness and Distributional Cost-Effectiveness of Semaglutide for Obesity Treatment. 西马鲁肽治疗肥胖的传统成本-效果和分配成本-效果。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-07 DOI: 10.1002/oby.70311

Neeti S Kulkarni, David Hutton, Corwin Rhyan, Jeffrey S McCullough, Michaela Greenlee, Ankur Pandya

{"title":"The Conventional Cost-Effectiveness and Distributional Cost-Effectiveness of Semaglutide for Obesity Treatment.","authors":"Neeti S Kulkarni, David Hutton, Corwin Rhyan, Jeffrey S McCullough, Michaela Greenlee, Ankur Pandya","doi":"10.1002/oby.70311","DOIUrl":"https://doi.org/10.1002/oby.70311","url":null,"abstract":"Objective: This study aimed to evaluate the conventional and distributional cost-effectiveness of semaglutide, laparoscopic sleeve gastrectomy (LSG), and a \"do nothing\" option in Black and White racial subgroups.Methods: A Markov simulation model was developed from a healthcare perspective over a 25-year time horizon for Black and White adults, aged 65-70, with BMI ≥ 35 and cardiovascular disease. Three interventions were modeled: semaglutide 2.4 mg, LSG, and \"do nothing.\"Results: Semaglutide and LSG interventions are cost-effective compared to a \"do nothing\" strategy (ICERs = $7300/QALY and $12,100/QALY, respectively). Compared to semaglutide, LSG is more expensive but cost-effective (ICER = $53,700/QALY). Semaglutide is more equitable but is not distributionally cost-effective compared to LSG, because it has a lower EDE within our defined inequality aversion (ε) range. Across 10,000 probabilistic iterations, LSG has a 57% probability and semaglutide has a 43% probability of being the most cost-effective at the willingness-to-pay threshold of $100,000/QALY. Semaglutide becomes distributionally cost-effective when ε ≥ 14.72, where equity impacts of semaglutide outweigh the conventional cost-effectiveness outcomes.Conclusions: LSG is the most conventionally cost-effective treatment option with some uncertainty. Semaglutide is marginally more equitable than LSG but is not a distributionally cost-effective strategy.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149129737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Building the Business Case for Access to Obesity Treatment. 建立获得肥胖治疗的商业案例。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-06 DOI: 10.1002/oby.70305

Akio Kozato, Babak J Orandi, Manish Parikh, Karan R Chhabra

引用次数: 0

Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity. 频繁与单次运动对超重/肥胖成人运动行为和能量平衡的影响存在差异。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-06 DOI: 10.1002/oby.70310

Heloisa C Santo Andre, Elisa Le Roux, Nathan P De Jong, Patricia R Smith, Andrew H Lange, Carlos Mendez, Alexandre Zahariev, Melissa L Mamele, Ginger Johnson, Zhaoxing Pan, Chantal Simon, Daniel H Bessesen, Ana J Pinto, Audrey Bergouignan

{"title":"Frequent Versus Single Active Bouts Differentially Affect Movement Behavior and Energy Balance in Adults With Overweight/Obesity.","authors":"Heloisa C Santo Andre, Elisa Le Roux, Nathan P De Jong, Patricia R Smith, Andrew H Lange, Carlos Mendez, Alexandre Zahariev, Melissa L Mamele, Ginger Johnson, Zhaoxing Pan, Chantal Simon, Daniel H Bessesen, Ana J Pinto, Audrey Bergouignan","doi":"10.1002/oby.70310","DOIUrl":"10.1002/oby.70310","url":null,"abstract":"Objective: This study aimed to investigate the effects of breaking up sedentary behavior (SB) on daily movement behavior and energy balance in adults with overweight/obesity.Methods: Thirty participants (16F/14M; 34.2 ± 7.3 years; 29.5 ± 3.2 kg/m2) were randomized to either BREAK (multiple 5-min brisk walking bouts) or a duration-matched intervention, ONE (45-min brisk walking), performed 5 days/week for 6 weeks. At pre- and post-intervention, daily SB and physical activity (PA; accelerometry), body composition (doubly labeled water [DLW]), total daily energy expenditure (TDEE; DLW), appetite, and fasting leptin were measured. Linear mixed-effects models tested time effects and group-by-time interactions.Results: Only BREAK reduced prolonged SB (interaction: p = 0.043). Both groups shifted SB-PA composition toward greater moderate-to-vigorous PA, with proportional reductions in SB and light PA (time: all p ≤ 0.011). These changes in PA level were associated with increased TDEE (time: p = 0.040). ONE showed small increases in body and fat mass compared with BREAK (interaction: both p ≤ 0.061). No differences were noted in metabolizable energy intake, appetite, or leptin levels.Conclusions: Spreading short PA bouts throughout the day increases moderate-to-vigorous PA and TDEE to the same extent as a traditional continuous PA bout. Future studies should investigate whether the modest body composition changes observed across interventions are driven by distinct behavioral/physiological compensations influenced by the daily pattern of PA/SB.Trial registration: ClinicalTrials.gov: NCT02998892.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149121158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity. 极低碳水化合物饮食对老年肥胖患者肌间脂肪组织和肌肉功能的影响。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-06 DOI: 10.1002/oby.70316

Carly E Drake, Barbara A Gower, Kevin R Fontaine, David R Bryan, Amy M Goss

{"title":"The Effect of a Very Low-Carbohydrate Diet on Intermuscular Adipose Tissue and Muscle Function in Older Adults With Obesity.","authors":"Carly E Drake, Barbara A Gower, Kevin R Fontaine, David R Bryan, Amy M Goss","doi":"10.1002/oby.70316","DOIUrl":"https://doi.org/10.1002/oby.70316","url":null,"abstract":"Objective: Intermuscular adipose tissue (IMAT) is associated with impaired skeletal muscle (SM) quality and declining mobility in older adults with obesity. This secondary analysis examined the effects of a very low-carbohydrate diet (VLCD) versus a low-fat diet (LFD) on changes in IMAT, muscle strength, and physical function in older adults with obesity.Methods: Adults (age ≥ 60 years) with obesity were randomized to a weight-maintaining VLCD (< 10% energy from carbohydrates) or LFD (55% energy from carbohydrates) for 8 weeks. Thigh SM and IMAT were measured by MRI. Physical function was assessed via hand grip strength, isometric knee extension, reach score, and six-minute walk tests. Multiple linear regressions examined whether changes in IMAT were associated with changes in physical function outcomes.Results: The VLCD group showed a significantly greater decrease in IMAT (-24.4% vs. -1.0%, p < 0.01). Across all participants, greater decreases in IMAT were associated with greater improvements in hand grip strength (r2 = 0.95, p < 0.01), isometric knee extension (r2 = 0.88, p < 0.05), and reach score (r2 = 0.75, p < 0.05), after adjusting for changes in thigh SM volume and body weight.Conclusions: Dietary interventions that reduce IMAT, such as a VLCD, may help preserve physical function and muscle strength in older adults with obesity.Trial registration: ClinicalTrials.gov identifier: NCT02760641.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149121171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

tsRNAs Mediate Intergenerational Inheritance by Concertedly Suppressing Wnt and PPAR Pathways. tsRNAs通过共同抑制Wnt和PPAR通路介导代际遗传。

Obesity (Silver Spring, Md.) Pub Date : 2026-10-06 DOI: 10.1002/oby.70303

Jinzhao Zhou, Lijun Liu, Yanwei Zhang, Yayun Qin, Meiqi Yi, Ting Wang, Jian Hu, Jieping Song, Ling Zeng

{"title":"tsRNAs Mediate Intergenerational Inheritance by Concertedly Suppressing Wnt and PPAR Pathways.","authors":"Jinzhao Zhou, Lijun Liu, Yanwei Zhang, Yayun Qin, Meiqi Yi, Ting Wang, Jian Hu, Jieping Song, Ling Zeng","doi":"10.1002/oby.70303","DOIUrl":"https://doi.org/10.1002/oby.70303","url":null,"abstract":"Objective: The Developmental Origins of Health and Disease hypothesis posits that paternal environmental exposures program offspring metabolic health via sperm epigenetic factors, particularly tRNA-derived small RNAs (tsRNAs). Cadmium (Cd) is a ubiquitous environmental pollutant known to impair reproductive health, but epigenetic links to offspring metabolic disorders are unclear. Using paternal Cd exposure, we elucidate sperm tsRNA pathogenic mechanisms in intergenerational inheritance.Methods: We validated candidate tsRNA functions via zygotic microinjection of agomirs in mice and transfection in AML12 cells in vitro. For mechanistic insights, we conducted blastocyst low-input RNA sequencing, liver transcriptomics, and in vitro assays (luciferase, Western blot, immunofluorescence).Results: Transfection of Cd-upregulated sperm tsRNAs (tRF-Leu-CAA, tRF-Ala-AGC) inhibited PPAR signaling in AML12 cells and caused lipid disorders. In vivo, microinjection recapitulated paternal Cd effects: impaired embryogenesis and adult metabolic syndromes (weight gain, hyperlipidemia, hepatic steatosis). Mechanistically, tsRNAs suppressed Wnt and PPAR pathways from the two-cell stage, with LEF1/WNT5A as direct Wnt targets; this suppression persisted in adult liver.Conclusions: We propose a two-hit mechanism: first hit via early embryonic Wnt/PPAR co-suppression, second hit via sustained inhibition into adulthood, driving metabolic dysregulation. Thus, tsRNAs are key epigenetic vectors linking paternal Cd exposure to offspring metabolic health.","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149121194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0