Bernard Tang, Suresh Anand Sadananthan, Delicia Shu Qin Ooi, Natarajan Padmapriya, Mya Thway Tint, Elaine Kwang-Hsia Tham, Daniel Yam Thiam Goh, Birit F P Broekman, Joshua J Gooley, Oon Hoe Teoh, Yap-Seng Chong, Peter D Gluckman, Fabian Yap, Johan G Eriksson, S Sendhil Velan, Falk Müller-Riemenschneider, Yung Seng Lee, Navin Michael, Shirong Cai
{"title":"符合建议睡眠时间与10岁男孩下腹部脂肪组织有关","authors":"Bernard Tang, Suresh Anand Sadananthan, Delicia Shu Qin Ooi, Natarajan Padmapriya, Mya Thway Tint, Elaine Kwang-Hsia Tham, Daniel Yam Thiam Goh, Birit F P Broekman, Joshua J Gooley, Oon Hoe Teoh, Yap-Seng Chong, Peter D Gluckman, Fabian Yap, Johan G Eriksson, S Sendhil Velan, Falk Müller-Riemenschneider, Yung Seng Lee, Navin Michael, Shirong Cai","doi":"10.1002/oby.70026","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine sex-stratified associations between meeting recommended sleep duration and adiposity in 10-year-old children.</p><p><strong>Methods: </strong>Using the GUSTO cohort (51% boys, 10.2 ± 0.2 years), we evaluated the associations of meeting sleep duration recommendations (total daily sleep duration of ≥ 9 h, caregiver-reported and actigraphy) throughout the week with obesity and BMI z-scores (N = 638), glycoprotein acetyls (n = 436), fat mass measured by quantitative magnetic resonance (n = 528), and abdominal adipose tissue volumes measured by magnetic resonance imaging (N = 377). Multivariable linear and logistic regressions were used, adjusted for ethnicity and maternal education.</p><p><strong>Results: </strong>Boys, but not girls, whose caregiver-reported sleep duration met recommendations throughout the entire week had a lower risk of obesity (BMIz > 2.0) (OR = 0.49, 95% CI 0.27-0.87), BMIz (0.34 ± 0.16 vs. 0.98 ± 0.12) (p = 0.001), glycoprotein acetyls levels (0.65 ± 0.01 mmol/L vs. 0.70 ± 0.01 mmol/L) (p < 0.001), total fat mass (8.77 ± 0.69 kg vs. 11.31 ± 0.51 kg) (p = 0.002), and deep subcutaneous (492 ± 86 mL vs. 729 ± 56 mL) (p = 0.014), superficial subcutaneous (651 ± 85 mL vs. 888 ± 55 mL) (p = 0.013), and visceral (415 ± 51 mL vs. 557 ± 33 mL) (p = 0.013) adipose tissue volumes.</p><p><strong>Conclusions: </strong>Interventions to help children attain recommended sleep duration for weekdays and weekends may reduce abdominal and total adiposity, especially in boys.</p>","PeriodicalId":94163,"journal":{"name":"Obesity (Silver Spring, Md.)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Meeting Sleep Duration Recommendations is Associated With Lower Abdominal Adipose Tissue in 10-Year-Old Boys.\",\"authors\":\"Bernard Tang, Suresh Anand Sadananthan, Delicia Shu Qin Ooi, Natarajan Padmapriya, Mya Thway Tint, Elaine Kwang-Hsia Tham, Daniel Yam Thiam Goh, Birit F P Broekman, Joshua J Gooley, Oon Hoe Teoh, Yap-Seng Chong, Peter D Gluckman, Fabian Yap, Johan G Eriksson, S Sendhil Velan, Falk Müller-Riemenschneider, Yung Seng Lee, Navin Michael, Shirong Cai\",\"doi\":\"10.1002/oby.70026\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>This study aimed to examine sex-stratified associations between meeting recommended sleep duration and adiposity in 10-year-old children.</p><p><strong>Methods: </strong>Using the GUSTO cohort (51% boys, 10.2 ± 0.2 years), we evaluated the associations of meeting sleep duration recommendations (total daily sleep duration of ≥ 9 h, caregiver-reported and actigraphy) throughout the week with obesity and BMI z-scores (N = 638), glycoprotein acetyls (n = 436), fat mass measured by quantitative magnetic resonance (n = 528), and abdominal adipose tissue volumes measured by magnetic resonance imaging (N = 377). Multivariable linear and logistic regressions were used, adjusted for ethnicity and maternal education.</p><p><strong>Results: </strong>Boys, but not girls, whose caregiver-reported sleep duration met recommendations throughout the entire week had a lower risk of obesity (BMIz > 2.0) (OR = 0.49, 95% CI 0.27-0.87), BMIz (0.34 ± 0.16 vs. 0.98 ± 0.12) (p = 0.001), glycoprotein acetyls levels (0.65 ± 0.01 mmol/L vs. 0.70 ± 0.01 mmol/L) (p < 0.001), total fat mass (8.77 ± 0.69 kg vs. 11.31 ± 0.51 kg) (p = 0.002), and deep subcutaneous (492 ± 86 mL vs. 729 ± 56 mL) (p = 0.014), superficial subcutaneous (651 ± 85 mL vs. 888 ± 55 mL) (p = 0.013), and visceral (415 ± 51 mL vs. 557 ± 33 mL) (p = 0.013) adipose tissue volumes.</p><p><strong>Conclusions: </strong>Interventions to help children attain recommended sleep duration for weekdays and weekends may reduce abdominal and total adiposity, especially in boys.</p>\",\"PeriodicalId\":94163,\"journal\":{\"name\":\"Obesity (Silver Spring, Md.)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-10-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Obesity (Silver Spring, Md.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1002/oby.70026\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Obesity (Silver Spring, Md.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1002/oby.70026","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
目的：本研究旨在探讨符合推荐睡眠时间与10岁儿童肥胖之间的性别分层关系。方法：使用GUSTO队列（51%的男孩，10.2±0.2岁），我们评估了一周内满足睡眠时间建议（每日总睡眠时间≥9小时，照顾者报告和活动记录）与肥胖和BMI z-评分（N = 638）、糖蛋白乙酰（N = 436）、定量磁共振测量的脂肪量（N = 528）和磁共振成像测量的腹部脂肪组织体积（N = 377）的关系。采用多变量线性和逻辑回归，并根据种族和母亲教育程度进行调整。结果：男孩，而不是女孩，其看护人报告的睡眠时间在整个星期符合建议的肥胖风险较低（BMIz bbb2.0） （OR = 0.49, 95% CI 0.27-0.87）， BMIz(0.34±0.16 vs. 0.98±0.12)(p = 0.001)，糖蛋白乙酰水平（0.65±0.01 mmol/L vs. 0.70±0.01 mmol/L） (p结论：帮助儿童达到推荐的工作日和周末睡眠时间的干预措施可以减少腹部和总体肥胖，尤其是男孩。
Meeting Sleep Duration Recommendations is Associated With Lower Abdominal Adipose Tissue in 10-Year-Old Boys.
Objective: This study aimed to examine sex-stratified associations between meeting recommended sleep duration and adiposity in 10-year-old children.
Methods: Using the GUSTO cohort (51% boys, 10.2 ± 0.2 years), we evaluated the associations of meeting sleep duration recommendations (total daily sleep duration of ≥ 9 h, caregiver-reported and actigraphy) throughout the week with obesity and BMI z-scores (N = 638), glycoprotein acetyls (n = 436), fat mass measured by quantitative magnetic resonance (n = 528), and abdominal adipose tissue volumes measured by magnetic resonance imaging (N = 377). Multivariable linear and logistic regressions were used, adjusted for ethnicity and maternal education.
Results: Boys, but not girls, whose caregiver-reported sleep duration met recommendations throughout the entire week had a lower risk of obesity (BMIz > 2.0) (OR = 0.49, 95% CI 0.27-0.87), BMIz (0.34 ± 0.16 vs. 0.98 ± 0.12) (p = 0.001), glycoprotein acetyls levels (0.65 ± 0.01 mmol/L vs. 0.70 ± 0.01 mmol/L) (p < 0.001), total fat mass (8.77 ± 0.69 kg vs. 11.31 ± 0.51 kg) (p = 0.002), and deep subcutaneous (492 ± 86 mL vs. 729 ± 56 mL) (p = 0.014), superficial subcutaneous (651 ± 85 mL vs. 888 ± 55 mL) (p = 0.013), and visceral (415 ± 51 mL vs. 557 ± 33 mL) (p = 0.013) adipose tissue volumes.
Conclusions: Interventions to help children attain recommended sleep duration for weekdays and weekends may reduce abdominal and total adiposity, especially in boys.
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