Neurorehabilitation and neural repair最新文献

{"title":"Cortical Activation During Split-Belt Treadmill Walking in People With Parkinson's Disease and Healthy Controls.","authors":"Femke Hulzinga, Paulo Henrique Silva Pelicioni, Nicholas D'Cruz, Veerle de Rond, Christopher McCrum, Pieter Ginis, Moran Gilat, Alice Nieuwboer","doi":"10.1177/15459683251329882","DOIUrl":"10.1177/15459683251329882","url":null,"abstract":"<p><p>BackgroundPeople with Parkinson's disease (PwPD) have difficulty adapting their gait to asymmetrical conditions. <i>Objective.</i> We investigated cortical activity between 42 PwPD (HY 2-3) and 42 healthy controls using functional near-infrared spectroscopy during tied-belt (TB) and split-belt (SB) treadmill walking.MethodsOxygenated hemoglobin (HbO2) was measured in the prefrontal cortex, supplementary motor area (SMA), premotor cortex (PMC), and posterior parietal cortex (PPC) during 3 blocks of treadmill walking: (1) with the belts moving at the same speed (TB) and (2) when the speed of 1 side was reduced by 50% (SB; 2 blocks). The ability to adjust gait to asymmetric conditions was quantified by step length asymmetry and its variability.ResultsAdaptive gait was worse during the last 5 steps of SB versus TB in PwPD compared to controls. PwPD showed higher HbO2 in the PMC (<i>P</i> = .005) and PPC (<i>P</i> = .004) relative to controls, regardless of condition. However, an increase in HbO2 in the SMA during SB was shown relative to TB in PwPD, a change not observed in controls (group × condition interaction <i>P</i> = .048; pairwise post hoc <i>P</i> = .032). Interestingly, increased PPC activity in PwPD was associated with poorer adapted gait.ConclusionsBoth regular and adaptive gait required enhanced cortical processing in PwPD, as evidenced by the increased activation in the PMC and PPC. However, this heightened cortical activity did not correlate with a reduction in gait asymmetry, suggesting that these changes might be maladaptive. Instead, the elevated cortical activity may reflect the challenges PwPD face in adapting to asymmetrical walking conditions. Careful interpretation is warranted given the relatively small sample of mildly affected PwPD, limiting generalizability to the broader population and the measurement errors inherent to functional near-infrared spectroscopy .</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"452-463"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond Arm Capacity in Chronic Stroke: Evaluating Paretic Arm Non-Use Through Arm Efficiency-A Cross-Sectional Study.","authors":"Gaël Le Perf, Germain Faity, Denis Mottet, Makii Muthalib, Isabelle Laffont, Karima Bakhti","doi":"10.1177/15459683241303691","DOIUrl":"10.1177/15459683241303691","url":null,"abstract":"<p><p>BackgroundAfter a stroke, the use of the paretic arm is determined by its capacity (what it can or cannot do). When both arms have capacity to perform a task, the choice of which arm to use must be based on another criterion, probably by comparing the efficiency of each arm. Two numerical models account for this: the capacity model (the paretic arm is chosen in preference) and the efficiency model (the most efficient arm is chosen).ObjectiveTo numerically determine whether capacity or efficiency best predict the use of the paretic arm in activities of daily living.MethodsWe performed numerical simulations to predict paretic arm use with either the capacity model or the efficiency model. We used the Bayesian Information Criterion (BIC) to compare the adequacy of the 2 models in predicting clinical and accelerometric data collected from 30 patients with chronic stroke.ResultsThe efficiency model predicted arm use in activities of daily living better than the capacity model (BIC = -66.95 vs -5.89; root mean square error = 0.26 vs 0.72).ConclusionsThe study highlights the importance of considering efficiency when assessing paretic arm non-use. Assessing individuals' arm efficiency should help personalize rehabilitation strategies after stroke.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"423-432"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171074/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating Motor Imagery Capabilities in Fatigued Versus Non-Fatigued Individuals With Multiple Sclerosis Without Cognitive Impairment.","authors":"Gizem Şekercan, Ayla Fil, Mehmet F Yetkin, Rana Karabudak, Aslı Tuncer, Yeliz Salcı","doi":"10.1177/15459683251331594","DOIUrl":"10.1177/15459683251331594","url":null,"abstract":"<p><p>BackgroundMotor imagery is adversely affected by various factors in individuals with multiple sclerosis (MS). However, the impact of MS-related fatigue on motor imagery remains unclear. Our study aimed to compare motor imagery abilities between fatigued and non-fatigued individuals with MS without cognitive impairment.MethodsThis study included 73 individuals with MS, with Expanded Disability Status Scale scores from 0 to 4.5. Participants were divided into 2 groups based on Fatigue Severity Scale scores: ≥4 for Fatigued Group and <4 for Non-fatigued Group. Assessment of motor imagery vividness was done through Kinesthetic and Visual Imagery Questionnaire-20 (KVIQ-20). The Box and Block Test (BBT) and the Timed Up and Go (TUG) were employed for the temporal congruence component.ResultsThe mean ages of the Fatigued Group (30.4 ± 9.2 years) and the Non-fatigued Group (31.5 ± 9.8 years) were similar (<i>P</i> = .650). The fatigued Group exhibited significantly lower kinesthetic imagery scores on the KVIQ-20 (<i>P</i> = .028) and significantly lower performance in the BBT (upper extremities) mental chronometry test for both the most affected and least affected sides of the upper extremities (<i>P</i> = .007 and .028, respectively). Additionally, the Fatigued Group showed significantly lower performance in the TUG (lower extremities) mental chronometry test (<i>P</i> = .006).ConclusionIn fatigued individuals with MS, there is a greater impact on both temporal congruence components and kinesthetic motor imagery abilities. The difference in the temporal congruence component was observed in tests involving both TUG (lower extremities) and BBT (upper extremities), independent of the affected side.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"473-480"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144059645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MEP Status is Not Predictive of Response to Upper Limb Training in People With Chronic, Moderate-Severe Hemiparesis Post-Stroke.","authors":"Erin C King, Michael Trevarrow, Sebastian Urday, Jacob M Schauer, Daniel M Corcos, Mary Ellen Stoykov","doi":"10.1177/15459683251327582","DOIUrl":"10.1177/15459683251327582","url":null,"abstract":"<p><p>BackgroundThe presence or absence of a motor evoked potential (MEP) in the post-stroke hemiparetic limb has been recommended by rehabilitation experts as a predictive biomarker which is ready for use in clinical trials. However, evidence remains limited for its prognostic value in the chronic stage.Objective:Determine if MEP status (MEP+ or MEP-) obtained within 1 week of starting treatment (baseline) predicts the magnitude of response to intervention in individuals with chronic, moderate-severe hemiparesis.MethodsThis is a retrospective analysis using data from a single-blind randomized controlled trial. Seventy-six individuals ≥6 months post-stroke with a baseline Fugl-Meyer Assessment of the Upper Extremity (FMUE) score of 23 to 40 underwent 30 hours of upper limb (UL) training over 6 weeks. Participants were stratified by baseline MEP status. The primary endpoint was change in FMUE score from baseline to post-test.ResultsSeventy-three participants provided FMUE scores and MEP status at baseline. Individuals who were MEP+ (n = 49) demonstrated a mean FMUE change score of 5.09 (standard deviation [SD] = 3.8) while MEP- (n = 24) individuals demonstrated a mean change score of 5.04 (SD = 4.0). There were no significant differences between the groups (mean difference = 0.05, <i>P</i> = .96, 95% confidence interval [-1.99, 2.09]).ConclusionsOur results demonstrate that MEP status at the start of an intervention in the chronic stage does not predict recovery for people with moderate-severe UL impairments. This finding directly challenges recent expert recommendations to stratify trial groups by MEP status, suggesting that such stratification may not effectively reduce variability or predict treatment response at the chronic stage.Clinical Trial Registration:ClinicalTrials.gov, ID: NCT03517657.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"445-451"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12173793/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of the Wolf Motor Function Test (WMFT) and Its Modified Versions: A Systematic Review With Meta-Analysis.","authors":"Lorena Sabrina Pometti, Daniele Piscitelli, Alessandro Ugolini, Francesco Ferrarello, Francesco Notturni, Andrea Coppari, Serena Caselli, Fabio La Porta, Mindy F Levin, Leonardo Pellicciari","doi":"10.1177/15459683251327568","DOIUrl":"10.1177/15459683251327568","url":null,"abstract":"<p><p>BackgroundThe Wolf Motor Function Test (WMFT) and its modified versions are widely used to assess upper limb (UL) function in stroke survivors. However, comprehensive evaluations of its psychometric properties are lacking.ObjectiveTo perform a systematic review with meta-analysis on the psychometric properties (following the COnsensus-based Standards for the selection of health Measurement INstruments [COSMIN] taxonomy) of the WMFT and modified versions in stroke survivors.MethodsSix databases were searched until May 2024 for studies examining at least one WMFT measurement property in stroke patients. Two independent reviewers conducted study selection, data extraction, and quality assessment using the COSMIN Risk of Bias checklist and quality of evidence (QoE) with the Grading of Recommendations Assessment, Development, and Evaluation approach. Meta-analyses synthesized psychometric properties reported in at least two studies.ResultsTwenty-five studies (N = 2044) were included. Regarding the WMFT Functional Ability Scale (FAS) and TIME scales, internal consistency (alpha ≥ .88), intra-rater (intraclass correlation coefficient [ICC] ≥ .97) and inter-rater (ICC ≥ .92) reliability, measurement error for TIME, construct validity (strong correlations [<i>r</i> ≥| .64|] with Fugl-Meyer Assessment and Action Research Arm Test), and responsiveness (ES ≥ 0.48) were rated sufficiently with QoE from very low to high. Measurement error for FAS was assessed as inconsistent with moderate QoE, and cross-cultural validity was rated as indeterminate with very low QoE. Content validity was not assessed. Few studies investigated the psychometric properties of the modified versions.ConclusionsWMFT demonstrates robust psychometric properties in assessing UL function in stroke survivors. While the WMFT-modified versions showed promising properties, further research is needed to use them. Future studies should focus on WMFT measurement error, content, and cross-cultural validity.Trial Review Registration:PROSPERO: CRD42021237425.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"400-420"},"PeriodicalIF":3.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upper Extremity-Cognitive Dual-Task Capacity Post-Stroke.","authors":"Yishai Bachar Kirshenboim, Shir Tzur Lebovich, Tal Weitzer, Dana Doron, Moshe Bondi, Ron Cialic, Debbie Rand","doi":"10.1177/15459683251317192","DOIUrl":"10.1177/15459683251317192","url":null,"abstract":"<p><p>BackgroundDual-task capacity, which might be impaired poststroke, is needed for daily functions. Therefore, dual-task capacity should be assessed during rehabilitation. The Dual Overload Interference Test (DO-IT) is a new upper extremity (UE) protocol for assessment, combining The Box and Block Test with the Counting Backwards Test.ObjectivesTo validate DO-IT by comparing between (1) young and older healthy, (2) stroke and healthy participants. Additionally, to correlate DO-IT with (3) walking-cognitive dual-task assessment (healthy), and (4) standardized cognitive and EF assessments (stroke).MethodsA cross-sectional study included younger and older community-dwelling healthy individuals (N = 32), and younger and older individuals with stroke (N = 83). DO-IT was administered to all participants. The #blocks transferred (motor) and #correct numbers counted (cognitive) were recorded for single and dual conditions. The walking-cognitive dual-task test was administered to the healthy participants. Motor and cognitive costs were calculated as the difference between single and dual tasks. The Montreal Cognitive Assessment test (MoCA) and the Color Trail Test (CTT) assessed cognition post stroke.ResultsOlder healthy adults had significantly lower dual-task motor capacity compared to younger adults (median [interquartile range] blocks: older 26 [21-38], younger 46 [38-52], <i>P</i> < .01). Participants with stroke showed higher motor costs than healthy participants. Dual-task costs correlated between DO-IT to walking-cognitive (motor; <i>r</i> = .37-.41, cognitive; <i>r</i> = .41-.47, <i>P</i> < .05). DO-IT motor cost negatively correlated with MoCA (<i>r</i> = -.27, <i>P</i> < .05), and DO-IT motor performance correlated with MoCA/CTT-AB (<i>r</i> = .29-.60, <i>P</i> < .05).ConclusionsUE-Cognitive dual-task capacity is affected post-stroke. DO-IT shows potential for use in stroke rehabilitation and its validity should be further researched.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"365-376"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Relevance of the Tonic Stretch Reflex Threshold and μ as Measures of Upper Limb Spasticity and Motor Impairment After Stroke.","authors":"Daniele Piscitelli, Joy Khayat, Anatol G Feldman, Mindy F Levin","doi":"10.1177/15459683251318689","DOIUrl":"10.1177/15459683251318689","url":null,"abstract":"<p><p>BackgroundAfter a central nervous system lesion, the ability to control muscle activation and relaxation in specific joint ranges may be impaired. The underlying mechanism of this sensorimotor impairment is related to a decreased ability to regulate the tonic stretch reflex threshold (TSRT) through descending and peripheral control processes. In dynamics, the reflex threshold and its velocity-sensitivity (μ) describe how movement in specific upper limb (UL) joint ranges is impaired after stroke.ObjectiveTo examine the relationships between measures of elbow flexor impairment using TSRT and μ, and clinical scores of spasticity and motor function. We hypothesized that TSRT and μ would be related to clinical spasticity and motor impairment scores in patients with acute and chronic stroke.MethodsTSRT, μ, and clinical data of the resistance to passive movement (Modified Ashworth Scale) and UL motor function (Fugl-Meyer Assessment [FMA]) were collected from 120 patients. Relationships between variables were determined using simple correlations and multiple regression analysis.ResultsTSRT and μ explained 72.0% of the variance in the FMA of the Upper Extremity [FMA-UE] describing only in-synergy and out-of-synergy movements and reflex function. TSRT explained 68.7% of the variance in the total score of the FMA-UE.ConclusionsThis study shows for the first time, a significant relationship between deficits in TSRT regulation and μ with UL motor impairment after stroke. TSRT and μ may be valuable clinical biomarkers of sensorimotor impairment for monitoring spontaneous or treatment-induced motor recovery.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"386-399"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Talking While Walking After Concussion: Acute Effects of Concussion on Speech Pauses and Gait Speed.","authors":"Shu Yang, Paula K Johnson, Colby R Hansen, Elisabeth A Wilde, Melissa M Cortez, Leland E Dibble, Peter C Fino, Tiphanie E Raffegeau","doi":"10.1177/15459683251317184","DOIUrl":"10.1177/15459683251317184","url":null,"abstract":"<p><p>BackgroundDeficits in dual-tasks (DT) are frequently observed post-concussion (ie, mild Traumatic Brain Injury). However, traditional DT may not be relevant to daily life. Walking while talking elicits DT costs in healthy adults and is part of daily life.ObjectiveWe investigated the effect of concussion on walking with extemporaneous speech and explored relationships between DT and acute symptoms.MethodsParticipants with recent concussion (<14 days post-injury) and controls completed 3 tasks: single-task gait without speaking (ST_G), single-task speaking without walking (ST_S), and walking while speaking (DT). Silent pauses in speech audio reflected cognitive performance, and gait was quantified using inertial sensors. We used linear mixed models to compare groups and conditions and explored associations with self-reported symptoms.ResultsBoth concussion (n = 19) and control (n = 18) groups exhibited longer speech pauses (<i>P</i> < .001), slower walking speeds (<i>P</i> < .001), and slower cadence (<i>P</i> < .001) during the DT compared to ST conditions. There were no group differences or interactions for speech pauses (<i>P</i> > .424). The concussion group slowed down more during DT than the control group (group × task <i>P</i> = .032). Vestibular symptoms strongly associated with ST speech pause duration (ρ = .72), ST gait speed (ρ = -.75), and DT gait speed (ρ = -.78).ConclusionsExtemporaneous speech is well-practiced but challenging to complete while walking post-concussion. Strong associations between DT outcomes and vestibular-related symptoms suggest DT deficits vary with post-concussion symptomology. DT deficits may be deleterious to daily tasks post-concussion.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"355-364"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12078015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Phase Multiple Sclerosis Patients Present Substantial Deficits in Physical-, Cognitive-, and Patient-reported Outcomes Compared to Matched Healthy Controls.","authors":"Cecilie Thrue, Lars G Hvid, Mette Diechmann, Tobias Gaemelke, Egon Stenager, Ulrik Dalgas, Morten Riemenschneider","doi":"10.1177/15459683251318246","DOIUrl":"10.1177/15459683251318246","url":null,"abstract":"<p><p>BackgroundEarly identification of potential deficits is of utmost importance as early diagnosis and early treatment has been shown to be crucial to reduce disease activity and disease impact-leading to the notion of \"Time matters\" in multiple sclerosis (MS).ObjectiveThe aim of the present study was to compare physical-, cognitive-, and patient-reported outcomes in early phase MS patients with matched healthy controls (HC).MethodsThis cross-sectional study included 84 patients early in the disease course of MS (≤2 years from diagnosis) and 84 age- and sex-matched HC. All participants underwent a comprehensive test battery including physical-, cognitive-, and patient-reported outcomes.ResultsRelative deficits for patients with MS compared to HC corresponded to 7% to 35% in walking capacity (Timed 25-Foot Walk Test, 6 Spot Step Test, 6 Minute Walk Test), 5% for upper limb function (9 Hole Peg Test), 27% for aerobic capacity (maximal oxygen uptake), 17% to 38% for physical activity level (Baecke Sport Index and accelerometer counts/minute), 68% for fatigability (Walking Fatigability Index), 150% for fatigue (Modified Fatigue Impact Scale), 4% to 20% for cognitive function (Symbol Digit Modalities Test, Paced Auditory Serial Addition Test, and Selective Reminding Test), and lastly, 7% to 8% for quality of life (Short Form-36 health survey). Only the Symbol Digit Modalities Test and Selective Reminding Test Delayed did not differ between groups, statistically.ConclusionEarly phase MS patients present substantial deficits in physical-, cognitive-, and patient-reported outcomes compared to HC. These early impairments highlight the importance of early initiatives aimed at preserving and/or building of reserve capacity.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"377-385"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143412198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"High Intensity Interval Training POst-STroke (HIIT-POST): Perspectives of People Living With Stroke and Health Professionals.","authors":"Sarah K Ashcroft, Liam Johnson, Suzanne S Kuys, Angelica G Thompson-Butel","doi":"10.1177/15459683251317185","DOIUrl":"10.1177/15459683251317185","url":null,"abstract":"<p><p>BackgroundHigh intensity interval training (HIIT) is a mode of aerobic exercise that can increase neurotrophin concentration, improve cardiovascular health, and enhance recovery post-stroke. However, HIIT is not commonly prescribed in stroke rehabilitation. Exploring the clinical utility of, and barriers and facilitators to, HIIT is necessary to optimize clinical use.ObjectiveTo identify perceptions of HIIT from people with stroke and health professionals working in stroke rehabilitation.MethodsPeople with stroke and health professionals in Australia were invited to participate in an online questionnaire. Participants were further invited to complete a one-on-one semi-structured interview. A Framework Analysis approach was applied to identify key themes.ResultsTwenty-six people with stroke (mean ± standard deviation = 49.2 ± 60.6 months post-stroke, 57.7% female) and 37 health professionals (2 medical and 35 allied health) completed questionnaires. Ten people with stroke (5 female) and 8 allied health professionals completed an interview. Aerobic exercise was not considered a priority after stroke, though participants were interested in HIIT. People with stroke reported a lack of understanding of the benefits of HIIT and use of the term \"high intensity\" as barriers to participation. Facilitators included education about safety of HIIT and referral to health professionals. Health professionals reported a lack of knowledge of HIIT prescription parameters and participant motivation as barriers to prescription. Facilitators included education of HIIT prescription and benefits and appropriate screening prior to commencement.ConclusionsPeople with stroke and health professionals are interested in HIIT after stroke. Increasing knowledge and confidence to participate in, and prescribe HIIT, may increase clinical use.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"343-354"},"PeriodicalIF":0.0,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065947/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}