Yannick Darmon, Shailesh Kantak, Hannah Cone, Niko Fullmer, Debra Ouellette, Carolee Winstein, Emily R Rosario, Nicolas Schweighofer
{"title":"Speed-Biased Training Temporarily Improves Motor Performance of the Paretic Arm Compared to Accuracy-Biased Training in Chronic Stroke Survivors: The Phase 1 FAST Randomized Clinical Trial.","authors":"Yannick Darmon, Shailesh Kantak, Hannah Cone, Niko Fullmer, Debra Ouellette, Carolee Winstein, Emily R Rosario, Nicolas Schweighofer","doi":"10.1177/15459683251331582","DOIUrl":"10.1177/15459683251331582","url":null,"abstract":"<p><p>BackgroundDespite the prevalence of upper extremity (UE) limitations after stroke, few training interventions prioritize fast movement speeds during rehabilitation.ObjectivesTo compare the effects of an equivalent dose (in the number of trials) of speed versus accuracy training in chronic stroke with mild-to-moderate impairments who have no direct cerebellar damage.Patients and MethodsIn this Phase-1 randomized controlled trial, we randomized 42 participants to either a speed or an accuracy arm-movement training condition. Participants moved their paretic hands through complex tracks, with 2080 trials in 4 sessions within a week. Speed and accuracy were manipulated by displaying 5 cm-wide or 1.25 cm-wide tracks or providing feedback based on average speed and accuracy in the Speed and Accuracy groups, respectively. We measured changes in kinematics in a 3-target test, in the speed-accuracy trade-off in a modified Fitts' test of the paretic arm during goal-directed reaching, and clinical outcomes (ie, UE Fugl-Meyer, Action Research Arm Test, and Box and Block Test) at 3 days and 1-month post-training.ResultsSpeed training led to significantly faster and smoother movements with more symmetric reach velocity profiles at the 3-day post-test, consistent with better feedforward control. Speed training temporarily improved the speed-accuracy tradeoff. At 1 month, however, most gains in the 3-target test and in the modified Fitts' test were lost.ConclusionSpeed training led to greater gains in kinematics of goal-directed actions than accuracy training, notably in a 3-day post-test. Our results suggest that training programs with high repetitions of fast movements may improve paretic arm reaching performance. The trial is registered at ClinicalTrials.gov under ID NCT05013762.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"542-554"},"PeriodicalIF":3.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tina Tian, Kevin Patel, David Kim, HaoMin SiMa, Alandrea R Harris, Jordan N Owyoung, Patricia J Ward
{"title":"Conditioning Electrical Stimulation Fails to Enhance Sympathetic Axon Regeneration.","authors":"Tina Tian, Kevin Patel, David Kim, HaoMin SiMa, Alandrea R Harris, Jordan N Owyoung, Patricia J Ward","doi":"10.1177/15459683251335321","DOIUrl":"10.1177/15459683251335321","url":null,"abstract":"<p><strong>Background: </strong>Peripheral nerve injuries are common, and there is a critical need for the development of novel treatments to complement surgical repair. Conditioning electrical stimulation (ES; CES) is a novel variation of the well-studied perioperative ES treatment paradigm. CES is a clinically attractive alternative because of its ability to be performed at the bedside prior to a scheduled nerve repair surgery.</p><p><strong>Objectives: </strong>Although 60 minutes of CES has been shown to enhance motor and sensory axon regeneration, the effects of CES on sympathetic regeneration are unknown. We investigated how 2 clinically relevant CES paradigms (10 and 60 minutes) impact sympathetic axon regeneration and distal target reinnervation.</p><p><strong>Results: </strong>Our results indicate that the growth of sympathetic axons is inhibited by CES at acute time points, and at a longer survival time point post-injury, there is no difference between sham CES and the CES groups. Furthermore, 10-minute CES did not enhance motor and sensory regeneration with a direct repair, and neither 60-minute nor 10-minute CES enhanced motor and sensory regeneration through a graft.</p><p><strong>Conclusion: </strong>We conclude sympathetic axons may retain some regenerative ability, but no enhancement is exhibited after CES, which may be accounted for by the inability of the ES paradigm to recruit the small-caliber sympathetic axons into activity. Further studies will be needed to optimize ES parameters to enhance the regeneration of all neuron types.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"515-528"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to: Murakami et al. (2023).","authors":"","doi":"10.1177/15459683251341565","DOIUrl":"10.1177/15459683251341565","url":null,"abstract":"","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"584-587"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Brian M Sandroff, Robert W Motl, Roberto S Hernandez, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D Chiaravalloti, Gary R Cutter, Ulrik Dalgas, John DeLuca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Maria A Rocca, Amber Salter, Anthony Feinstein
{"title":"Correlates of Processing Speed Change With Combined Cognitive Rehabilitation and Exercise in Progressive MS: Secondary Analysis of the CogEx Trial.","authors":"Brian M Sandroff, Robert W Motl, Roberto S Hernandez, Maria Pia Amato, Giampaolo Brichetto, Jeremy Chataway, Nancy D Chiaravalloti, Gary R Cutter, Ulrik Dalgas, John DeLuca, Rachel Farrell, Peter Feys, Massimo Filippi, Jennifer Freeman, Matilde Inglese, Cecilia Meza, Maria A Rocca, Amber Salter, Anthony Feinstein","doi":"10.1177/15459683251331586","DOIUrl":"10.1177/15459683251331586","url":null,"abstract":"<p><p>BackgroundCognitive rehabilitation and exercise training are promising approaches for improving cognition in persons with progressive multiple sclerosis (MS). Identifying heterogeneity of change and factors that influence the effects of cognitive rehabilitation and/or exercise training on cognitive outcomes at the individual level have direct relevance for developing tailored and optimized rehabilitation interventions for improving cognition in progressive MS.ObjectiveThis study involved a secondary data analysis from the CogEx trial in progressive MS. This study first described heterogeneity of change in cognitive processing speed (CPS) across the intervention conditions and then identified possible adherence/compliance, baseline performance, and demographic/clinical variables as correlates of rehabilitation-related CPS changes.MethodsA total of 311 persons with progressive MS who were pre-screened for impaired CPS completed 12 weeks of combined cognitive rehabilitation (or sham) and exercise training (or sham). CPS was measured before and after the 12-week period. As potential correlates of CPS changes, we measured adherence/compliance (ie, treatment exposure), performance outcomes at baseline, as well as demographic and clinical characteristics at baseline.ResultsThere was heterogeneity of change in CPS across the 4 intervention conditions. We further identified baseline learning and memory impairment and premorbid intelligence quotient (IQ), but not adherence/compliance, other baseline performance outcomes, or demographic/clinical characteristics as significant correlates of CPS changes across the 4 intervention conditions.ConclusionsThe overall pattern of results suggests that future trials in this area might account for impaired learning and memory and/or premorbid IQ as potential covariates, or more carefully consider the role of reserve within rehabilitation interventions in progressive MS.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"499-514"},"PeriodicalIF":3.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144048803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jason K Longhurst, Andrew Hooyman, Franziska Albrecht, Erika Franzén, Daniel S Peterson
{"title":"Discordance Between Balance Ability and Perception and Its Relation to Falls in Parkinson's Disease: A Replication Analysis.","authors":"Jason K Longhurst, Andrew Hooyman, Franziska Albrecht, Erika Franzén, Daniel S Peterson","doi":"10.1177/15459683251335316","DOIUrl":"10.1177/15459683251335316","url":null,"abstract":"<p><strong>Background: </strong>Falls are a common challenge for people with Parkinson's disease (PwPD), driven by balance impairments and misaligned perceptions of balance abilities.</p><p><strong>Objective: </strong>This study investigated the replicability and generalizability of the relationship between balance ability and perception discordance and fall risk.</p><p><strong>Methods: </strong>Using baseline data from 2 clinical trials involving 171 PwPD, discordance was calculated using the Activities Specific Balance Confidence Scale and Timed Up and Go (TUG) or the Mini Balance Evaluation System's Test (MiniBEST).</p><p><strong>Results: </strong>Findings supported the replicability of discordance as a predictor of fall risk, with results consistent across measures. While TUG-derived discordance was statistically significant, MiniBEST-derived discordance showed generalizability without statistical inferiority.</p><p><strong>Conclusion: </strong>These results emphasize the relevance of balance perception and its misalignment with ability as fall risk predictors.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"555-558"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256189/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035185","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacob Sindorf, Silvia Campagnini, Megan K O'Brien, Aashna Sunderrajan, Kristen L Knutson, Phyllis C Zee, Lisa Wolfe, Vineet M Arora, Arun Jayaraman
{"title":"Sleep Following a Stroke: Multimodal Evaluation of Sleep Health and Disruptions and Impact on Recovery During Acute Inpatient Rehabilitation.","authors":"Jacob Sindorf, Silvia Campagnini, Megan K O'Brien, Aashna Sunderrajan, Kristen L Knutson, Phyllis C Zee, Lisa Wolfe, Vineet M Arora, Arun Jayaraman","doi":"10.1177/15459683251335332","DOIUrl":"10.1177/15459683251335332","url":null,"abstract":"<p><p>BackgroundOur understanding of sleep during early stroke care and its impact on rehabilitation outcomes remains limited. The objectives of this work were to (1) evaluate multidimensional sleep health and disruptions during acute inpatient rehabilitation for individuals with stroke, and (2) explore the relationship between sleep health/disruptions and functional recovery.MethodsData from 103 individuals with stroke were analyzed during acute inpatient rehabilitation. Sleep health/disruptions were assessed via patient reports, actigraphy, and biometric sensors. Functional outcomes were measured at admission and discharge. Generalized Linear Models (GLMs) were used to describe changes in sleep health over time, and multivariate regressions analyzed sleep disruptions and sleep-related predictors of functional recovery.ResultsOver inpatient stays, sleep improved with a 23% reduction in wake after sleep onset and 15% fewer multiple overnight disruptions. GLMs revealed that improved sleep quality was associated with reduced overnight activity and increased heart rate over time. Poor initial sleep quality and cognitive status were associated with more overnight disruptions. Lastly, minimal associations were found between sleep health and functional recovery.ConclusionsSleep health during inpatient stroke rehabilitation is generally poor, though improves over time. Sleep is affected by neurological recovery and hospital environment. Overnight activity and autonomic biomarkers were associated with perceived sleep health, and both physiological and environmental factors triggered disruptions. The association between functional recovery and indirect indicators of sleep health requires further investigation. These findings reveal new insights about inpatient sleep which can inform early, targeted sleep interventions to optimize post-stroke outcomes.SIESTA, ClinicalTrials.gov (NCT04254484).</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"529-541"},"PeriodicalIF":0.0,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256198/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognition and Measures of Physical Activity, Mobility, and Gait in Individuals With Multiple Sclerosis: A Systematic Review.","authors":"Myeongjin Bae, Michael VanNostrand","doi":"10.1177/15459683251335315","DOIUrl":"10.1177/15459683251335315","url":null,"abstract":"<p><p>IntroductionImpairments in cognition are prominent for individuals with multiple sclerosis (MS) and have been linked to low levels of physical activity (PA) and walking impairment. However, this relationship remains inconsistent, necessitating the synthesis of current literature to yield collective knowledge.ObjectiveTo investigate the relationship between cognition and measures of PA, mobility, and gait quality in individuals with MS.MethodsRelevant, peer-reviewed research articles were identified through a systematic search of MEDLINE, EMBASE, PsycINFO, SPORTSDiscus, and CINAHL from inception to April 2, 2024. Eligible studies explored the relationship between cognition and measures of PA, mobility, and gait quality. The Standard Quality Assessment Criteria for quantitative studies was employed for quality assessment.ResultsTwenty-six studies with a total of 3248 participants were identified in this review, of which 21 studies indicated strong methodological quality. Our review found that processing speed holds a significant relationship with PA volume, but not PA intensity metrics. Mobility and gait quality outcomes were associated with varying cognitive domains, including processing speed, executive function, verbal memory, and visuospatial memory. The magnitudes of the association between cognition and PA, mobility, and gait quality were mostly weak-to-moderate.ConclusionProcessing speed appears to be collectively associated with PA volume, mobility, and gait quality. However, the evidence supporting this conclusion is largely based on correlational studies involving individuals with mild-to-moderate ambulation disability, warranting future research.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"559-577"},"PeriodicalIF":3.7,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammad Haghani Dogahe, Mark A Mahan, Miqin Zhang, Somaye Bashiri Aliabadi, Alireza Rouhafza, Sahand Karimzadhagh, Alireza Feizkhah, Abbas Monsef, Mehryar Habibi Roudkenar
{"title":"Advancing Prosthetic Hand Capabilities Through Biomimicry and Neural Interfaces.","authors":"Mohammad Haghani Dogahe, Mark A Mahan, Miqin Zhang, Somaye Bashiri Aliabadi, Alireza Rouhafza, Sahand Karimzadhagh, Alireza Feizkhah, Abbas Monsef, Mehryar Habibi Roudkenar","doi":"10.1177/15459683251331593","DOIUrl":"10.1177/15459683251331593","url":null,"abstract":"<p><p>Background and ObjectivesProsthetic hand development is undergoing a transformative phase, blending biomimicry and neural interface technologies to redefine functionality and sensory feedback. This article explores the symbiotic relationship between biomimetic design principles and neural interface technology (NIT) in advancing prosthetic hand capabilities.MethodsDrawing inspiration from biological systems, researchers aim to replicate the intricate movements and capabilities of the human hand through innovative prosthetic designs. Central to this endeavor is NIT, facilitating seamless communication between artificial devices and the human nervous system. Recent advances in fabrication methods have propelled brain-computer interfaces, enabling precise control of prosthetic hands by decoding neural activity.ResultsAnatomical complexities of the human hand underscore the importance of understanding biomechanics, neuroanatomy, and control mechanisms for crafting effective prosthetic solutions. Furthermore, achieving the goal of a fully functional cyborg hand necessitates a multidisciplinary approach and biomimetic design to replicate the body's inherent capabilities. By incorporating the expertise of clinicians, tissue engineers, bioengineers, electronic and data scientists, the next generation of the implantable devices is not only anatomically and biomechanically accurate but also offer intuitive control, sensory feedback, and proprioception, thereby pushing the boundaries of current prosthetic technology.ConclusionBy integrating machine learning algorithms, biomechatronic principles, and advanced surgical techniques, prosthetic hands can achieve real-time control while restoring tactile sensation and proprioception. This manuscript contributes novel approaches to prosthetic hand development, with potential implications for enhancing the functionality, durability, and safety of the prosthetic limb.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"481-494"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Machine Learning-Based Model for Prediction of Early Post-Stroke Fatigue in Patients With Stroke: A Longitudinal Study.","authors":"Yu Wu, Depeng Zhou, Lovel Fornah, Jian Liu, Jun Zhao, Shicai Wu","doi":"10.1177/15459683251329893","DOIUrl":"10.1177/15459683251329893","url":null,"abstract":"<p><p>BackgroundPost-stroke fatigue, as one of the long-lasting physical and mental symptoms accompanying stroke survivors, will seriously affect the daily living ability and quality of life of stroke patients.ObjectiveThe aim of this study was to develop machine learning (ML) algorithms to predict early post-stroke fatigue among patients with stroke.MethodsA longitudinal study of 702 patients with stroke followed for 3 months. Twenty-three clinical features were obtained from medical records and questionnaires before discharge. Early post-stroke fatigue was assessed using the Fatigue Severity Scale. The dataset was randomly divided into a training group (70%) and an internal validation group (30%), applied oversampling, 10-fold cross-validation, and grid search to optimize the hyperparameter. Feature selection using the Least Absolute Shrinkage and Selection Operator (LASSO) regression. Sixteen ML algorithms were performed to predict early post-stroke fatigue in this study. Accuracy, precision, recall, <i>F</i>1 score, area under the receiver operating characteristic curve (AUC), and brier score were used to evaluate the models performance.ResultsAmong the 16 ML algorithms, the Bagging model was the optimal model for predicting early post-stroke fatigue in patients with stroke (AUC = 0.8479, accuracy = 0.7518, precision = 0.5741, recall = 0.7209, <i>F</i>1 score = 0.6392, brier score = 0.1490). The feature selection based on LASSO revealed that risk factors for early post-stroke fatigue in patients with stroke included anxiety, sleep, social support, family care, pain, depression, neural-functional defect, quit/no drinking, balance function, type of stroke, sex, heart disease, smoking, and hemiplegia.ConclusionsIn this study, the Bagging model proved to be effective in predicting early post-stroke fatigue.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"433-444"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143694991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Peii Chen, Natalia Noce, Emily DeBel, Jayme O'Connor, John DeLuca
{"title":"Prism Adaptation Treatment May Reduce In-Hospital Falls Among Individuals With Spatial Neglect After Stroke.","authors":"Peii Chen, Natalia Noce, Emily DeBel, Jayme O'Connor, John DeLuca","doi":"10.1177/15459683251327569","DOIUrl":"10.1177/15459683251327569","url":null,"abstract":"<p><p>BackgroundSpatial neglect (SN) is a risk factor of in-hospital falls among stroke survivors. Our prior study showed that receiving more sessions of prism adaptation treatment (PAT) in inpatient rehabilitation facilities (IRFs) predicted greater SN reduction and functional improvement.ObjectiveTo identify circumstances of falls specific to SN and explore whether increasing PAT sessions may reduce fall incidence.MethodsThe present study was a retrospective analysis of fall-related documentation, clinical data and notes regarding SN assessment, and treatment as part of standard care. Records of 3020 patients admitted to an IRF after stroke were reviewed, and 1489 (49%) had SN based on the Catherine Bergego Scale (CBS).ResultsA total of 276 patients (9% of all patients) fell at least once during their IRF stay, and 173 fallers (67% of all fallers) had SN. SN increased fall incidence (incident rate ratio [IRR] = 1.44, <i>P</i> = .005) after controlling for 5 covariates including age, sex, cognitive and motor functional level at admission, and length of stay. While independent of type or cause of falls, SN was associated with location of falls-SN increased fall incidence in hospital rooms (IRR = 1.55, <i>P</i> = .024), after controlling for the 5 covariates. 62 (36%) of fallers with SN received a median of 4.5 PAT sessions (range = 1-11; interquartile range = 2-10). Increased PAT sessions were associated with fewer falls after PAT (IRR = 0.82, <i>P</i> = .022), controlling for the 5 covariates and 2 additional factors including CBS and number of falls before PAT.ConclusionsTreatment for SN such as PAT should be considered to reduce the risk of falls in these patients. Future research is needed to determine fall prevention measures for stroke survivors with SN, especially in their hospital rooms.</p>","PeriodicalId":94158,"journal":{"name":"Neurorehabilitation and neural repair","volume":" ","pages":"464-472"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143702461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}