Mymensingh medical journal : MMJ最新文献

{"title":"Clinical and Radiological Presentation of Patients with Smear Positive Pulmonary Tuberculosis.","authors":"S M Noor, M M Ahmad, K M R Anwar, M F Chowdhury, M Sultana, M A Kader, M A S Khan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chest X-ray is an important diagnostic aid frequently used alongside microscopic smear of sputum for the confirmation of pulmonary tuberculosis (TB). However, there is a dearth of literature investigating the clinical and radiological pattern of sputum positive pulmonary TB among adults in Bangladesh. The current study explored these patterns in presentation. This descriptive cross-sectional study was conducted at outpatients in department of medicine of a tertiary care hospital. A total of 50 newly diagnosed adult cases of smear positive pulmonary TB attending at the Directly Observed Treatment Short-course (DOTS) corners were consecutively included. Informed written consent was taken before inclusion. Data were collected through face-to-face interview. Radiological presentation was explored using chest X-ray. Data were analyzed by SPSS version 26.0. The average age of patients was 41.0±17.12 years and majority were male (78.0%). The most prevalent respiratory symptom was cough (80.0%) followed by constitutional symptom like fever (70.0%) and weight loss (72.0%). Wasting was the predominant sign (60.0%). Radiologically both lungs were involved in 32.0%, left lung were involved in 30.0% cases and right lung were involved in 26.0% of cases. Twelve percent (12.0%) of patients had normal chest X-ray. Upper zone involvement was commonly observed in this study's patients (66.0%). The predominant pattern was consolidation (46.0%) followed by fibrosis (26.0%), nodular opacity (12.0%), collapse (10.0%), cavity (6.0%), pleural effusion (2.0%) and bronchiectasis (2.0%). Findings of this study would help familiarize and identify the common clinical and radiological presentations of sputum positive pulmonary TB patients in day-to-day practice.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Probiotics as Adjuvant to the Standard Triple Therapy for the Treatment of Helicobacter Pylori-Associated Peptic Ulcer Disease: A Randomized-Control Trial.","authors":"B N Saha, M A M Sarkar, M N Hasan, A B Kamrul-Hasan, S C Das, M R Alam, M S Chowdhury, M R Khan, P K Roy, M A Kabir","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Helicobacter pylori (H. pylori) is a major cause of peptic ulcer disease (PUD), which needs effective eradication of the organism to heal ulcers and prevent a recurrence. In recent years, increasing resistance of H. pylori to clarithromycin and amoxicillin have decreased peptic ulcer cure rate following treatment with standard triple therapy worldwide. The addition of probiotics with standard triple therapy has shown excellent efficacy in H. pylori eradication and has appeared to be an alternative treatment strategy. This study aimed to assess the efficacy of standard triple therapy plus probiotics for H. pylori eradication and ulcer healing compared to standard triple therapy alone. This double-blind, randomized placebo-controlled clinical trial included 158 with endoscopically proven H. pylori-positive PUD who were randomly allocated equally into two groups; Group A was treated with standard triple therapy plus probiotics, and Group B was treated with standard triple therapy plus placebo for 14 days. The outcome was evaluated at the end of treatment (14th day) (symptoms plus adverse events) and after 60 days of treatment completion (H. pylori eradication and ulcer healing). One hundred forty four (144) study subjects (73 in Group A and 71 in Group B) completed the study. Significantly higher H. pylori eradication rate (82.2%vs. 67.6%, p=0.043) and ulcer healing rate (92.3% vs. 60.0%, p=0.049) were observed in the standard triple therapy plus probiotic group than the standard triple therapy plus placebo group. Early relief of epigastric pain was also seen among patients getting probiotics than the placebo in addition to standard triple therapy (42.3% vs. 15.1%, p<0.001).The addition of probiotics significantly improves the H. pylori eradication rate and ulcer healing rate among the patients getting standard triple therapy. Further large-scale, multi-center studies are needed to recommend routine use of probiotics with standard triple therapy for H. pylori eradication.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vitamin A, C and E levels in patients with Non-Alcoholic Fatty Liver Disease: An Indian Cohort Study.","authors":"S Mondithoka, N K Vikram, P Ranjan, M Pandey, A Seth, R Lakshmy, D Javed, V Malhotra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study aimed to investigate the levels of vitamins A, C, and E in patients with Non-Alcoholic Fatty Liver Disease (NAFLD) compared to healthy controls and to explore the correlation between these vitamin levels and various other parameters, including bone mineral density (BMD), adiposity (fat storage), insulin resistance and subclinical inflammation. The study involved 50 participants diagnosed with NAFLD and 50 healthy controls. Blood samples were collected to measure vitamin A, C and E levels, along with other parameters like insulin, inflammatory markers, and liver function tests. Additionally, participants underwent DEXA scans to assess BMD and body composition. Vitamin levels: The study found no significant deficiencies in vitamin A or C levels in either group. However, vitamin E levels were significantly higher in the NAFLD group compared to controls, although only one case of vitamin E deficiency was observed in the NAFLD group. No significant correlations were found between vitamin levels and BMD, adiposity parameters, insulin resistance, or subclinical inflammation markers in either group. The study acknowledges the limited data available on the association between NAFLD, vitamin levels and BMD in the Asian Indian population. The findings regarding vitamin A and C levels are consistent with some previous studies, whereas the higher vitamin E levels in the NAFLD group contradict other research. This discrepancy might be due to factors like sample size, dietary habits, or vitamin fortification programs. The lack of significant correlations between vitamin levels and other parameters suggests that further research is needed to understand the complex interplay between these factors in NAFLD development and progression.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Acceptance and Awareness of GPT-Based AI for Health Assistance in Clinical Practice among Registered Physicians of Bangladesh.","authors":"M N H Nishan, S M K Shams, M N U Ahmed, S Sultana, M D H Hawlader, J U Ahmmad","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the changing field of healthcare, AI models based on GPT technology have the potential to bring about changes in how diseases are diagnosed and treated. Despite global enthusiasm, there is a critical gap in exploring the acceptance and awareness of these AI tools among doctors in Bangladesh. This investigation becomes crucial as it navigates the challenges faced by physicians in middle-income countries like Bangladesh, providing a foundation for future implementations and advancements in AI-assisted healthcare. Therefore, this study aims to explore the acceptance and awareness of GPT-based AI for clinical practice among doctors in Bangladesh. In this study, we looked at 398 registered physicians in Bangladesh. The research used a convenient sampling method and employed a questionnaire to collect information. The size of the sample was chosen using a calculation for a 95% confidence level. Statistical analysis included looking at combined data, calculating frequencies and percentages well, and using the Chi-square test and multivariate logistic regression bivariate and multivariate analysis was done. All statistical analysis was done using Stata 17 software. This study examines GPT-based AI acceptance and awareness among Bangladeshi physicians. Key findings reveal a prevalence of 26.13% for acceptance and 71.11% for awareness. Acceptance significantly varies with age (p=0.013), preferring those aged 21-30. Gender (p=0.001) influences awareness, showing in females. Physicians aged 41-50 exhibit lower acceptance odds (AOR=0.13), and females have decreased acceptance odds (AOR=0.29). Demographics don't significantly impact awareness. This study sheds light on Bangladeshi doctors' views on GPT-based AI in healthcare. While some actively support its use, a majority are aware. Age, gender, and workplace influence acceptance. Tailored strategies are vital for addressing concerns. Future research should focus on understanding physicians' adoption of GPT-based AI.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parental Relationship and School Performance of Children.","authors":"N Yasmin, M Moniruzzaman, R Pervin, M R Karim, F Ahamed, S Hamid, F Yasmin, A K M Hossain, N E Tasnim, M A Rahman, M R Akter, N F Ahmed","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Parental relationship with children is the most natural, unique and enduring bond in the world gifted by God. As child's first education begins at home, so the quality of parental relationship with children may have an impact on child's life as well as school performance. The objective of this study was to find out the association between parental relationship and school performance of children. This was a cross sectional study where class six to ten children aged between 11-17 years was participants. Seven secondary schools were selected in Rajshahi city of Bangladesh for data collection. The self-administered questionnaire was used to find out the quality of parental relationship by using the Inventory of Parent and Peer Attachment (IPPA) scale. To asses school performance face to face interview was conducted to the corresponding class teachers as well as exam result and attendance were also taken from official records. The study period was one year from January 2019 to December 2019. Out of total 385 children, 53.5% were girls and 46.5% were boys. The mean age of the children was 13.63±1.289 years. Good quality of relationship with mother was 96.1% and poor-quality relationship was 3.9%. As well as good quality of relationship with father was 93.5% and poor-quality relationship was 6.5%. This study founded boys seemed to establish better relationships with mother compared to girls. Findings also revealed a positive significant association between children's relationship with their mothers and school performance. There was no significant relationship present between all socio-demographic characteristics and parental relationship except gender and occupation of father. This study found statistically significant relationship between parental relationship and school performance of children. Therefore, awareness among parents about parental relationship should be considered as a part of betterment of school performance.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic Obstructive Pulmonary Disease (COPD): A Preventable Cause of Death and Disability.","authors":"A Sharmin, A Nessa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Not Available.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Number of Germinal Centers of Vermiform Appendix in Bangladeshi People of Different Age and Sex.","authors":"S A Sumi, R A Naznin, S K Bose, L Jabeen, I Jahan, N Sultana, F R Momo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The vermiform appendix is a tubular, blind-ended secondary lymphoid organ located near the caecum, often referred to as the \"tonsil of the abdomen\" due to the abundance of lymphoid follicles in its histology. The presence of germinal centers, which are indicators of lymphatic tissue response to antigens and subsequent antibody production, helps assess the immune status of individuals. By counting these germinal centers, researchers can evaluate the immune status of the Bangladeshi population across different age and sex groups. This study was conducted at Mymensingh Medical College, approximately 120 km north of Dhaka, the capital of Bangladesh. Samples were randomly selected from the local population between 2016 and 2017, including 40 vermiform appendices from various age groups: Group A (up to 20 years), Group B (21-40 years), Group C (41-60 years) and Group D (over 60 years). After obtaining ethical approval, the germinal centers, identified by their lighter staining in the center of lymphoid follicles, were counted under a microscope (X4 objective, X10 eyepiece). The average number of germinal centers per age group was then calculated. The study found that the mean±SD number of germinal centers was 3.20±1.66, 2.40±0.66, 1.50±1.11 and 0.30±0.45 across the advancing age groups. The mean differences of number of germinal center between A&B, B&C were statistically non significant at p= or >0.05 level, difference between group C&D, A&C was statistically significant at p<0.05 level and differences between group B&D, A&D were statistically highly significant at p<0.001 level. Mean±SD number of germinal center of vermiform appendix in male was higher (3.60±1.02, 2.42±0.49, 1.50±1.26 and 0.33±0.47 in Group A, B, C and D respectively) than in female (2.80±1.17, 2.33±0.94, 1.30±0.87 and 0.25±0.43 in Group A, B, C and D respectively) but mean difference between sexes in the different groups was statistically non significant at p=or >0.05 level. Overall, the study observed a gradual decline in the number of germinal centers with increasing age.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paraumbilical Perforator Flap: A Reliable Option for Coverage of Soft Tissue Defects of Forearm and Hand.","authors":"A Sarker, S R Faruquee, R M Manzur, K N A Begum, O Z M Dastagir, M A Ali","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Soft tissue injuries of the hand or forearm often results in exposure of tendon or bone which needs coverage with a suitable flap. This prospective observational study was carried out in National Institute of Traumatology and Orthopaedic Rehabilitation (NITOR), Dhaka, Bangladesh from February 2019 to January 2020, to evaluate the use of the pedicled paraumbilical perforator flaps as a reliable flap to cover such defects. Total 34 patients having soft tissue defects in the hand and forearm with exposed tendons, bones or implant were included in this study. All the defects were covered by paraumbilical perforator flap. The defects were caused by road traffic accident (n=22), machinery injury (n=10) and burn injury (n=2). Sixteen patients had defects involving the forearm, six over dorsum of hand, another two over first web space and the rest had defects over two or more areas of forearm, hand and wrist. Lateral extent of flaps was upto anterior axillary line in 41.18% cases and upto mid-axillary line in 55.88% cases. Flap division and final inset was done in second stage after 3 weeks. Donor site closed primarily in all cases, except in two cases where it was covered by skin graft. All the flaps survived with no incidence of flap necrosis, dehiscence or infection after first stage. However, after the division of the flap, two patients developed marginal necrosis of the proximal margin which healed spontaneously by conservative treatment. The mean flap surface area utilized was 108 cm2. Donor area healed well without any major complications. Three patients developing scar hypertrophy were treated with intra-lesional triamcinolone injections. The paraumbilical perforator flap is a reliable option to cover soft tissue defects of hand and forearm due to easier planning and harvesting of the flap, adequate skin paddle and minimum donor site morbidity.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Study of Epileptic Burn Patient in a Tertiary Level Hospital of Bangladesh.","authors":"I Jahan, L K Dhar, A Kaiser, S Razia, M A Hossain, A Talukder","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Burns are very common and important injuries associated with epilepsy. Epileptics are afflicted with burns when they come in contact with fire or other burning agents while seizing, due to loss of consciousness. The aim of the study was to identify the causes of burn, pattern and characteristics of burn in patients with epilepsy, duration of hospital stay and pattern of treatment in these patients. This prospective observational study was conducted in the Department of Burn and Plastic Surgery, Mymensingh Medical College Hospital, Bangladesh from January 2022 to December 2023. Epileptics were found in 0.84% (n=19) of the total admission (2274) in Burn unit. Majority of the patients were females (84.2%) and the mean age was (31.42±1.32) years. Maximum patients were housewives (78.9%). Among 19 cases, 11 cases (57.89%) had history of irregularly taking antiepileptic drugs and 8 cases (42.11%) had no history of treatment for epilepsy. Two cases (10.53%) had history of previous burn injury. Flame burn was the major etiology (89.5%). Mean total burn surface area (TBSA) was (6.94±4.12%). Most patients had full thickness burns (63.2%). Regarding distribution of burn, maximum involvement was in upper limb i.e. 68.21% cases. Surgical treatment was needed in the majority of the patients (68.5%). Mean hospital stay of these patients was (5.36±2.26) weeks. Epilepsy patients whose seizures are inadequately controlled are at increased risks of injury, especially burn. For prevention of burn, epilepsy should be treated properly.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fetomaternal Outcome of Covid-19 Positive Pregnant Patients in Bangladesh: A Comparative Study.","authors":"U Ruman, K I Karim, M M Rhaman, F Begum","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Objective of the study was the effect of Covid-19 infection on pregnancy and neonatal outcomes. This prospective cohort study was conducted in Combined Military Hospital (CMH) Bogura, Obstetrics and Gynaecology department from June 2020 to October 2020. We have collected and analyzed data of 29 pregnant ladies positive for Covid-19. Control group was Covid-19 negative pregnant patients. Nasopharyngeal swab was taken for real time polymerase chain reaction for detection of Covid-19. We observed symptoms, compared any complication in mother and fetus, mode of termination, and duration of hospital stay. Only six patients were asymptomatic (10.3%). Fifteen (25.9%) had fever, six (6) had weakness (10.3%), 5(8.6%) had sore throat, 3(5.2%) had nausea and 5(8.6%) presented with loss of smell. Among twenty-nine patients, 5(8.6%) delivered normally, 24(41.4%) were delivered through caesarean section which was significantly higher than control group (p value <0.001). No mother became critical or expired, neonatal death was also absent. Mean duration of hospital stay was 14.13±6.192 days in case and 5.18±4.99 in control which was significantly (p value <0.001) higher. Breast feeding was significantly higher in control group (p value <0.001). This study shows feto-maternal outcome of Covid-19 pregnancy is almost same as those of normal pregnancy.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141474046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}