Mymensingh medical journal : MMJ最新文献

{"title":"Frequency of Microvascular and Macrovascular Complications among Newly Detected Type 2 Diabetes Mellitus Patients Attending in a Tertiary Care Hospital.","authors":"M R Karim, E Mondal, A Begum, J M A Islam, R Hossain, M F Pathan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microvascular and macrovascular or both types of complications is much more common in patients with longstanding diabetes mellitus. However, very few studies focused on the complication rate among newly detected type 2 diabetes mellitus patient. The objective of the study was to assess the frequency of micro and macrovascular complications among newly detected type 2 diabetes mellitus patients attending the Department of Endocrinology of BIRDEM General Hospital, Dhaka, Bangladesh. This cross-sectional study was conducted from January 2019 to December 2019. All study participants were screened according to inclusion and exclusion criteria and informed written consent was taken. Out of 311 respondents, the mean age was 53.28±8.84 years. Males were 63.7% and females were 36.3%. Among 311 respondents 52.7% (164) had complications and 47.3% (147) had no complication. Considering the total respondents (311), 40.2% respondents had microvascular complications, 7.7% had macrovascular complications and 4.8% had both micro and macrovascular complications. The frequency of Diabetic Neuropathy, Retinopathy, Nephropathy, CVD, CAD and PAD were 20.6%, 8.03%, 16.4%, 3.5%, 6.4% and 2.6% respectively. Considering risk factors 16.1% of respondents had a smoking habit, 47.9% were overweight and 29.9% were obese, besides 28.9% had hypertension. Hypertension, fasting plasma glucose, HbA1c, total cholesterol and LDL were significantly associated with neuropathy. Hypertension, fasting plasma glucose, HbA1c, LDL and urine for ACR were significantly associated with retinopathy. Hypertension, HbA1c, total cholesterol, LDL and urine for ACR were significantly associated with nephropathy. Smoking habits, HTN, fasting plasma glucose, 2 hours PG after OGTT, HbA1c, total cholesterol and LDL were significantly associated with CVD. Among the newly detected type 2 diabetes mellitus patients both micro and macrovascular complications were substantially found. Neuropathy was the predominant microvascular complication where was coronary artery disease was the most common macrovascular complication.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1114-1122"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Hypercalcemia with Advanced Oral Squamous Cell Carcinoma.","authors":"M I Ali, R Banik, A Jabeer, B Nowreen, M D H Bhuiyan, N Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Squamous cell carcinoma (SCC) is the most frequent type of oral cancer in the globe. Despite breakthroughs in overall treatment modalities, survival rates of individuals with oral squamous cell carcinoma (OSCC) have not improved appreciably. One of the reasons for OSCC's poor survival rate is late diagnosis. The majority of patients arrive at the hospital in advanced stages of the disease (stage-3 and stage-4). This cross-sectional comparative study was carried out in the Department of Oral and Maxillofacial Surgery of former Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, from September 2022 to August 2023. And aimed to find out the association of hypercalcemia with advanced oral squamous cell carcinoma (stage-3 and stage-4). The study was comprised of 84 subjects in which 42 were selected as case group with advanced Oral Squamous Cell Carcinoma (OSCC), reporting to the Department of Oral and Maxillofacial Surgery, BSMMU; fulfilling the inclusion and exclusion criteria. The control group of subjects was consisted with 42 healthy attendants of patients after fulfilling the inclusion and exclusion criteria. All these participants were assessed clinically and their detailed history was recorded, 5 ml of intravenous blood was collected using standard aseptic conditions. These samples were centrifuged and serum was seen separated as the top transparent layer. This separated serum was used immediately for quantitative determination of serum calcium by biochemistry automated analyzer: Alinity ci. Serum calcium level was calculated and expressed in mg/dl. The collected data was sorted, tabulated and statistically analyzed. Hypercalcemia (>10.50 mg/dl) was found in 10(23.8%) patients of case group and no one in control group. The mean serum calcium level was found 9.48±0.71 mg/dl in case group and 9.07±0.56 mg/dl in control group. The difference was statistically significant (p<0.05) between two groups. The findings of the study showed that mean serum calcium levels in OSCC patients were substantially higher than in healthy people in Bangladesh.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1052-1059"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083511","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Medical Personnel Understanding Regarding Cardiac Rehabilitation Among Cardiac Patients in Bangladesh Medical University.","authors":"F K Shoma, M F I Khaled, M A Shakoor, M A K Azad, Z R Chowdhury, M H Hoque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In Bangladesh, Cardiovascular diseases (CVDs) impose a significant healthcare and socioeconomic burden. Cardiac rehabilitation, a proven multidisciplinary approach, enhances the well-being of Cardiovascular disease (CVD) patients. However, there may be gaps in medical personnel's understanding of this vital intervention. This study, conducted at Bangladesh Medical University (BMU), Dhaka, Bangladesh a renowned cardiac care institution in Bangladesh, seeks to evaluate and improve medical professionals' knowledge, perceptions and attitudes regarding cardiac rehabilitation to enhance patient care and outcomes. The aim of this study was to identify the key factors influencing medical personnel's understanding of cardiac rehabilitation, including their training, experience and exposure to current guidelines. This cross-sectional observational study was conducted in the Department of Cardiology of Bangladesh Medical University (BMU), Dhaka, Bangladesh during the period from August 2022 to July 2023. In total 100 medical personnel included in the study. We found that the Mean±SD of age was 33.16±7.06 and the majority (80.0%) were female, followed by 20.0% who were male and 5.0% who were physicians. We also found that the majority of medical personnel have a positive understanding of cardiac rehabilitation. Cardiac rehabilitation (CR) is underutilized in Bangladesh, including among healthcare professionals. This study aims to enhance CR awareness and integration for better patient outcomes at Bangladesh Medical University, ultimately improving cardiovascular care in Bangladesh.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1241-1248"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Culture-Based Isolation of Leptospira Species from Human Urine at a Tertiary Care Hospital in Bangladesh.","authors":"S A Tasnim, M R Hasan, S N Niaz, N Haque, S A Nasreen, M R Nahar, N S Ishi, S Haque, M Sultana, M S Islam, A A Mamun, S K Paul","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Leptospirosis is a significant zoonotic disease and previous studies have confirmed its presence in Bangladesh. Despite its potential to cause severe illness and death, the disease is frequently under-recognized because of limited diagnostic facilities and insufficient clinical awareness. This cross-sectional descriptive type of observational study was aimed to isolate Leptospira spp. from human urine by culture in a resource-limited setting at Mymensingh Medical College, Mymensingh, Bangladesh from October 2024 to March 2025. A total of 20 urine samples from clinically suspected cases of leptospirosis were collected and cultured in modified Ellinghausen-McCullough-Johnson-Harris (EMJH) medium. The isolates were confirmed by nested PCR and Sanger sequencing targeting the 16S rRNA gene. Four isolates (20.0%) were recovered and identified as Leptospiraspp. by dark field microscopy and nested PCR. Culture positivity was highest (25.0%) in patients presenting within 5-7 days of illness and declined with longer fever duration, with no isolates detected after 15-20 days. A lower positivity rate was observed among patients with recent antibiotic use (1 case) compared to those without antibiotic exposure (3 cases). Phylogenetic analysis identified all isolates as Leptospira wolffii, closely related to previously reported strains from the Mymensingh area. These findings provide microbiological evidence of the ongoing circulation of Leptospira wolffii and demonstrate the utility of urine culture, alongside molecular methods, to enhance diagnostic capacity and epidemiological understanding in endemic settings.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1040-1045"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between Maximum Length and Mid-Shaft Circumference in Adult Human Fibulae in Bangladeshi Population.","authors":"T R Biswas, T Kar, S M A Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this osteometrical study was to note the correlation between maximum length and mid-shaft circumference of adult human fibula. In this study the materials contained total 300 (152 right and 148 left) fully ossified and dry human fibula samples and all those samples were selected through the purposive sampling technique from the Department of Anatomy, Mymensingh Medical College Mymensingh, Bangladesh from January 2023 to December 2023. Any malformed and non-calcified bones were prohibited from this study. Only adult and fully intact bones are applied in this study. All Data of this study were tabulated and statistically studied by using Microsoft Excel and SPSS software. The maximum length and mid-shaft circumference of the fibula was measured by using a metallic scale and a measuring tape. The mean±SD of maximum length of both sided fibula was found on right side 34.32±2.05 cm and on left side 34.40±2.26 cm respectively and the mean±SD of mid-shaft circumference of both sided fibula was found on right side 4.22±0.49 cm and 4.21±0.53 cm on left side. In this anatomical and statistical study a positive correlation was executed between the maximum length and mid-shaft circumference of fibulae and through the regression analysis hare we found r=0.258 on right side and r=0.427 on left sided fibula. The difference were statistically significant on both sides and p value was <0.001.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"996-1000"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Related Quality of Life in Patients with Inflammatory Bowel Disease in Department of Gastroenterology of Dhaka Medical College Hospital: An Observational Study.","authors":"S M Rahman, M A Islam, A A Siddique, S M Rahman, M M Alam, J Jeeba, P Ullah, M M Rahman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Inflammatory bowel diseases (IBD) consisting of Crohn's disease (CD) and Ulcerative colitis (UC) are chronic inflammatory disorders of the GI tract with various symptoms such as diarrhea, fatigue, weight loss and abdominal pain. Factors like extra intestinal manifestations, the effects of medical and surgical treatments, frequent hospitalizations that place substantial burden on the daily lives and cause significant impairment in their quality of life. Health related quality of life (HRQoL) assessment is totally separate entity for assessing the effectiveness of clinical activity and management. This study was performed to assess the impact of IBD on patients' Health Related Quality of Life using SF-36 questionnaire. This was a Cross sectional observational study conducted in the Department of Gastroenterology, Dhaka Medical College and Hospital, Dhaka, Bangladesh from October 2018 to September 2019. In total fifty (50) patients more than 18-year-old diagnosed as IBD were enrolled for the study. In this study, total 50 IBD patients were enrolled with male predominance 38(76.0%). The mean age of patients was 30.19 years in Ulcerative colitis and 30.39 years was in Crohn's Disease. Among total (n=50) patients, Ulcerative colitis were 32(64.0%) and Crohn's disease were 18(36.0%). In respect of disease activity 37(74.0%) were with active disease and 13(26.0%) were in remission. Clinical factors such as disease activity, disease severity, surgery, stricturing Crohn's disease were associated with significantly low HRQoL scores. No differences were found between HRQoL scores with Ulcerative colitis and Crohn's disease, location of diseases, medical therapies and duration of the disease. The evaluation of HRQoL by SF-36 for patients with IBD in clinical practice enhances the understanding of the disease impact on patients' lives and activities but also help us to manage the patients appropriately.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1107-1113"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical and Molecular Characterization of Children with Neonatal Diabetes: Experience from Bangladesh.","authors":"F Mohsin, K Azad, Z Hassan, N Islam, S Mahbuba, S Tayyeb, S E Flanagan, E D Franco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Neonatal diabetes mellitus (NDM) is a rare monogenic form of diabetes presenting before six months of age which can be permanent (PNDM) or transient (TNDM). In rare cases, NDM can be diagnosed between 6 and 12 months of age. Whilst TNDM is commonly associated with chromosome 6q24 methylation defects, the commonest causes of PNDM are KCNJ11 and ABCC8 gene mutations. This observational study's aim was to assess the clinical features and genetic aetiologies in patients with NDM diagnosed in Bangladesh. The clinical characteristics of 28 patients who presented with NDM from 2001 to 2018 in the in the department of Neonatology and Paediatrics, BIRDEM, Dhaka, Bangladesh were studied. Mutation analyses were carried out by DNA sequencing at Peninsula Molecular Genetics Laboratory, Exeter, UK. Thirteen patients were from 11 consanguineous families. Comprehensive genetic testing was performed on 24 patients. Out of the 28 patients studied, 18(64.0%) had PNDM, 7(25.0%) had TNDM and for 3 the subtype was not known. Causative mutations were detected in 22 of the 24(92.0%) who underwent genetic testing. This included 15 PNDM patients (ABCC8 31.0%, KCNJ11 25.0%, EIF2AK3 19.0%, INS 6.0%) and 7 TNDM patients (6q24 43.0%, ABCC8 29.0%, KCNJ11 14.0%, INS 14.0%). Among consanguineous families, mutations in the ABCC8 gene and E1F2AK3 were common. The median age at diabetes presentation was 80 days (3-210 days), median birth weight was 2250g (1000-3700g), mean gestational age 37.15±1.91 weeks (32-40 weeks). The mean blood glucose at presentation was 29.30±11.73mmol/L (14.0-61mmol/L) with 11 patients (39.0%) presenting with diabetic ketoacidosis. Outcome was good in majority of patents except those with Wolcott-Rallison syndrome due to homozygous EIF2AK3 mutation. All patients with KCNJ11 or ABCC8 NDM were transferred from insulin to sulphonylurea except one. Genetic testing identified mutations in 79.0% (22/28) of this study's NDM cohort. An early genetic diagnosis is essential for patients' clinical management and informing parents on recurrence risk.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1090-1098"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Urgent Surgical Outcome of Intracranial Subdural Empyema: A Case Presentation.","authors":"M S Hossain, M S A Siddique, M K Hossen, K Hassan, M S Uddin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Intracranial subdural empyema represents a rare yet severe infection affecting the brain. Advances in diagnostic techniques and therapeutic interventions have significantly decreased the previously observed mortality rate of 100.0% to a current range of 4.0-9.0%. This notable improvement can be attributed primarily to a reduction in the time taken to initiate treatment. The initial challenge lies in recognizing the potential presence of this condition. Numerous case reports, series and retrospective studies have contributed to the understanding of this issue; however, the clinical epidemiology has evolved over time. In the presented case, an unconscious patient underwent urgent surgical intervention, resulting in a swift postoperative recovery.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1300-1303"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preserving the Bone Envelope: A Prospective Observational Study of Closed Reduction and Ilizarov Circular Fixation for Open and Closed Distal Tibial Fractures.","authors":"M Kamruzzaman, M Z Hossain, M A Islam, M A Islam, S Akter","doi":"","DOIUrl":"","url":null,"abstract":"&lt;p&gt;&lt;p&gt;Distal tibial fractures are challenging injuries because of limited soft-tissue coverage, frequent high-energy mechanisms and the potential for soft-tissue compromise. Extensive surgical exposure may further disturb the local soft-tissue and biological environment. Ilizarov circular external fixation permits stable fixation with limited exposure of the fracture site. This prospective observational study evaluated fracture union, bone and functional outcomes and complications following closed or indirect reduction and Ilizarov circular external fixation in patients with open and closed distal tibial fractures and was conducted in the Department of Orthopaedics, Mymensingh Medical College Hospital, Bangladesh from 15 March 2018 to 15 March 2024. Forty skeletally mature patients with distal tibial fractures were treated with an Ilizarov circular external fixator. Fracture reduction was performed by closed or indirect manipulation under C-arm fluoroscopic guidance. Twenty patients had closed fractures and 20 had open fractures. Among the open fractures, 6 were Gustilo-Anderson Grade I, 9 Grade II and 5 Grade IIIA. Clinical and radiological outcomes were assessed during follow-up. Bone and functional outcomes were classified using the Association for the Study and Application of the Method of Ilizarov (ASAMI) criteria. There were 30 male patients (75.0%) and 10 female patients (25.0%), with a mean age of 28 years. The right tibia was involved in 28 patients (70.0%) and the left tibia in 12(30.0%). Road traffic accidents accounted for 28 injuries (70.0%), falls from height for 8(20.0%) and physical assault for 4(10.0%). The mean interval from injury to Ilizarov fixation was 5 days. All 40 fractures united during follow-up. The mean time to radiological union was 17.12 weeks (range, 14-20 weeks). The mean duration of external fixation was 195 days (range, 180-210 days). The mean follow-up was 12 months (range, 6-15 months), with a minimum follow-up of 6 months after frame removal. According to ASAMI bone criteria, 24 patients (60.0%) had excellent results, 12(30.0%) good results and 4(10.0%) fair results. No poor bone result was recorded. Functional results were excellent in 18 patients (45.0%), good in 16(40.0%), fair in 4(10.0%) and poor in 2(5.0%). Pin-tract infection occurred in 16 patients (40.0%), involving 20 wires. Most infections were managed with local wound care and oral antibiotics. Eight patients (20.0%) required exchange of loose wires. No limb-length discrepancy was recorded during follow-up. In this prospective single-center series, closed or indirect reduction followed by Ilizarov circular external fixation was associated with a high observed rate of fracture union and predominantly favorable bone and functional outcomes in open and closed distal tibial fractures. The technique provided stable fixation while limiting direct surgical exposure of the fracture site. The findings support Ilizarov circular fixation as a useful treatmen","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 4","pages":"1082-1089"},"PeriodicalIF":0.0,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149083452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Slow Music on Selected Stress Biomarkers among Stressful Young Individuals.","authors":"A H M Shahidullah, M Begum, S Akhter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Music is the combination of harmony of melody and rhythm. Music listening have been associated with decrease of physiological arousal, heart rate, blood pressure and reduction of cortisol levels. Pharmacological and non-pharmacological measures have been advocated to minimize the development of stress related diseases. Relaxation techniques and listening to music can prevent cardiovascular complications. Music can affect central and autonomic nervous system as well as endocrine system. This experimental study was conducted in the Department of Physiology, Chittagong Medical College, Chattagram, Bangladesh from January 2020 to December 2021. Total 60 subjects of first year MBBS, with equal number of male and female, studying in Chittagong Medical College, Chattagram, were included by stratified random sampling method according to inclusion and exclusion criteria. A questionnaire along with general information about previous diseases, medical and family history were filled up by the subjects. Stress biomarkers- systolic and diastolic blood pressure, perceived stress scale (PSS) score and serum cortisol were recorded before and after 15 minutes of music intervention for 15 days. Result was compiled and compared after data collection by using SPSS 25.0. Paired 't' tests were done to compare differences between pre and post-intervention values of different outcome parameters. P value <0.05 was considered as statistically significant. Stress biomarkers- systolic and diastolic blood pressure, perceived stress scale (PSS) score and serum cortisol were significantly reduced after 15 days music intervention. This study concludes that regular listening to slow music causes significant reduction of stress and improvement of cardiorespiratory endurance and quality of life.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"35 3","pages":"870-875"},"PeriodicalIF":0.0,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148355204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}