Mymensingh medical journal : MMJ最新文献

{"title":"HPV Vaccination in a Case of JORRP, a Variety of RRP in Bangladesh Medical College Hospital: A Case Report.","authors":"S Jebunnaher, T Mohammad, M A Jaigirdar, M A Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recurrent respiratory papillomatosis (RRP) is a rare disease which is caused by human papilloma virus (HPV). It is a warty growth in the upper airway may cause significant airway obstruction or voice change. Though it is rare but one with severe morbidity and occasional mortality. It is caused mostly by HPV 6 and 11. Juvenile-onset recurrent respiratory papillomatosis (JoRRP) which is Juvenile form of RRP affects children, most common between the ages of 1 to 4 years.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"290-294"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Drug Use Pattern in Dermatology Out-Patient Department: A Cross-Sectional Study in a Tertiary Care Teaching Hospital, Dhaka, Bangladesh.","authors":"H Begum, M A Baker, A N Asma, Z Rahman, A N Dina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Now-a-days, all over the world, skin disease are the fourth most common cause of disability. A significant amount of patient attending the dermatology outdoor of any major hospital in a daily basis. Irrational drug prescribing is a common contemplation in clinical practice. The present research work was commenced to study the drug use pattern and rationality of prescriptions of the patients be at Dermatology Out-Patient Department (OPD) of a tertiary care hospital. It was an observational, single center study, conducted among 600 patients attending the Dermatology OPD of Enam Medical College and Hospital (EMCH), Bangladesh for a period of six months by interviewing the patients and detailed were filled in predesigned form. Overall 600 drug instructions were collected and surveyed for demographic as well as dermatological profile. Antihistamine (16.95%), antibacterial (14.69%), antifungal (10.73%) and corticosteroids (8.47%) were the most recurrent class of drugs ordered. Combination form (oral + topical) was mostly instructed (61.80%). Polypharmacy was seen (3.54 drugs per prescription) in our study, very few drugs (1.97%) name were written by generic name. antihistamine were most frequently advised drug groups. Least amount of drugs was prescribed from Essential Drug List (EDL) of Bangladesh. Interim auditing is necessary to promote standard prescription.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"220-226"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of Helicobacter Pylori Infection with Functional Dyspepsia.","authors":"M R Karim, M S Alam, A Islam, M S Malek, M S Ahsan, E Mia, S Hossain","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Helicobacter pylori (H pylori) infection is known to be associated with dyspepsia for more than three decades. This study was conducted to investigate the frequency of H pylori infection in functional dyspepsia. Helicobacter pylori infection was detected by stool antigen tests were analyzed in 102 patients with functional dyspepsia. The functional dyspepsia was diagnosed according to Rome IV criteria as well as normal upper GI (Gastro-intestinal) endoscopy and abdominal ultrasonography within six months. In this study, H pylori infection rate diagnosed by the stool antigen test was detected to be 26.5% among the people with functional dyspepsia. Sex-based proportion H pylori infection was 21.2% for men and 29.0% for women with functional dyspepsia. The highest prevalent group with Helicobacter pylori infection was 30-39 years. In this study, 25.75% of rural participants and 27.78% of urban participants with functional dyspepsia were positive for H pylori. The stool antigen positive group and the stool antigen negative group were not significantly different in respect to age (p=0.29), sex (p=0.41) and residence (p=0.82). This study showed an increased stool antigen positivity rate for H pylori infection among the patients with functional dyspepsia. Further studies are required to determine the exact prevalence of H pylori among this group of patients.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"74-78"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anatomical and Surgical Neck Circumference of Adult Human Humerus.","authors":"S M A Haque, T Mehataz, F Afros, T Siddiquee, S Tanzeem, D Debnath, S Jahan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The upper end of the humerus consists of three necks such as anatomical neck, surgical neck and morphological neck. The anatomical neck of the humerus is the area just below the head of the humerus. The surgical neck of the humerus is the area just below the greater and lesser tubercle of the humerus. The morphological neck is the junction between the diaphysis and upper epiphysis. It is represented by an epiphyseal line in the adult bone. It is a true junction of the head with the shaft. Fracture of the anatomical neck of the humerus rarely occurs. Fracture of the surgical neck of the humerus is more common in the upper-end fracture. The aim of this study was to measure the anatomical neck and surgical neck circumference of the humerus. One hundred (right=43 and left=57) samples were selected through the purposive sampling technique for this cross-sectional descriptive study which was carried out in the Department of Anatomy, Mymensingh Medical College, Mymensingh, Bangladesh during the period of July 2021 to June 2022. Any damaged, unossified bones or fractured bones were excluded. Data were tabulated and statistically analyzed using Microsoft Excel and SPSS software. The mean±SD anatomical neck circumference of the right humerus was 131.418±10.445 mm and the left humerus was 128.982±9.795 mm. The mean±SD surgical neck circumference of the right humerus was 74.883±7.607 mm and the left humerus was 74.298±7.392 mm. The anatomical knowledge of the anatomical and surgical neck of the humerus is beneficial for anthropologists, orthopedic surgeons & radiologists in cases of proximal end fractures of the humerus.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"5-8"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriological Profile and Antibiogram of Blood Stream Infection in a Tertiary Teaching Hospital of Bangladesh.","authors":"K A Talha, M I Patwary, K Fatema, H Ahmad, F Selina, M S Bhuiyan, M Khatoon, G M M Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Blood stream infection (BSI) is of the most devastating infection of any hospital which has a high mortality. Staphylococcus aureus, coagulase-negative staphylococci (CONS) and enterococcus species are commonest isolated bacteria. This was a cross-sectional descriptive study conducted at the Sylhet Women's Medical College Hospital from October 2022 to March 2023. Total study period was 6 months. Data were collected from electronic medical record (EMR). Out of a total 1674 blood samples 315 samples were positive for blood culture (18.8%). The mean age of the participants was 15.6 year with a highest frequency in the below 20-year age group. Staphylococcus aureus was commonest isolated bacteria followed by CONS. Imipenem (89.0%), Piperacillin and Tazobactam (88.0%), Doxycycline (81.0%) and Amikacin (79.0%) were most sensitive antibiotics. Precise bacteriological profile and antibiogram is helpful for any institution to have an idea about the current infection pattern. Commonly used empirical antibiotics should be selected according to antibiogram of that particular hospital.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"186-191"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome of Percutaneous Nephrolithotomy by Using Pneumatic Lithotripsy Alone and In Combination with Ultrasonic Lithotripsy.","authors":"M S Rahaman, M H R Bhuiyan, P P Chowdhury, N P Biswas, M A Islam","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Percutaneous nephrolithotomy (PCNL) is the gold standard treatment for large kidney stones. Recent advancements in endoscopic technology and operative techniques have significantly increased the success rate of PCNL while reducing associated complications and morbidity. A key development contributing to this progress is the introduction of various new lithotripter techniques, which facilitate rapid stone fragmentation and clearance. The objective of the study was to compare the outcome of PCNL using pneumatic lithotripsy alone and combined lithotripsy (pneumatic and ultrasonic). This quasi-experimental study was conducted in the Urology Department of the National Institute of Kidney Diseases and Urology (NIKDU) in Dhaka, Bangladesh from April 2019 to March 2020. Thirty patients in Group A underwent PCNL using pneumatic lithotripsy, while another thirty patients in Group B underwent PCNL using combined lithotripsy. The two groups were compared in terms of stone size, operative time, hospital stay, hemoglobin loss, ancillary procedures, and initial and overall stone clearance rates. The mean age was 34.33±9.72 years (range 22-65 years) in Group A and 36.83±12.61 years (range 19-62 years) in Group B, with homogeneous distribution. There are 45 males and 15 females in two groups, resulting in a male-to-female ratio of 3:1. The mean stone size was 3.36±1.07 cm (range 2-6 cm) in Group A and 3.67±0.88 cm (range 2.4-6.0 cm) in Group B, with no significant differences between the groups. The mean operation time was significantly different: 67.50±13.2 minutes (range 40-86 minutes) for PCNL with pneumatic lithotripsy compared to 57.30±10.9 minutes (range 45-95 minutes) for combined lithotripsy (p<0.05). The mean postoperative hemoglobin drop was 1.37±0.50 g/dL in the pneumatic lithotripsy group, significantly higher than the 1.12±0.46 g/dL drop in the combined lithotripsy group (p<0.05). Other variables, including stone-free rate, postoperative hospital stay, and postoperative complications, showed no significant differences between the groups. The combined lithotriptripsy (pneumatic and ultrasonic) signify superior efficacy in PCNL compared to the pneumatic lithotriptripsy alone, as it remarkably reduces both the total operative time and blood loss.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Presence of qnr and aac(6́)-Ib-cr Genes among Quinolone Resistant Proteus species Isolates at Mymensingh, Bangladesh.","authors":"P Arafa, M M Hoque, S K Paul, R Mazid, S S Nila, S Khan, A Paul, T Hossain, S A Nasreen, S Ahmed, N Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Fluroquinolone resistance among the Enterobacteriaceae including Proteus spp. is a serious public health problem as it is used for treating many clinical infections including UTI and intra-abdominal infections. Now-a-days, plasmid- mediated quinolone resistance (PMQR) has presented with considerable attention that can spread from one bacterium to another. So, the aim of this study was to detect the presence of qnr type (qnr A, B, D and S) and aac(6́)-Ib-cr genes among clinical isolates of ciprofloxacin resistance Proteus species .This cross-sectional study was carried out in the Department of Microbiology, Mymensingh Medical College, Mymensingh, Bangladesh from March 2020 to February 2021. Antimicrobial susceptibility test of 60 Proteus spp. isolates were done by disc diffusion technique. Among them, 48(80.0%) ciprofloxacin resistant isolates were detected during disk-diffusion technique and MIC of ciprofloxacin was performed among ciprofloxacin resistant Proteus isolates using agar dilution method. Amplification with uniplex specific primers of quinolone resistance genes (qnrA, qnrB, qnrD, qnrS and aac(6́)-Ib-cr) were performed out of quinolone resistant Proteus spp. isolates. Out of 48 Proteus species, Quinolone resistance genes were found positive 22(45.83%) for aac(6́)-Ib-cr, 9(18.75%) for qnrD, 6(12.5%) for qnrA and 3(6.25%) for qnrS. None of the strain was positive for qnrB gene. In total, 64.58% ciprofloxacin resistant Proteus isolates were positive for at least one PMQR gene. In this study, presence of high rate (64.5%) of PMQR genes as well as co-existence (30.0%) of the multiple genes among Proteus spp. is highly alarming, because fast dissemination could occur due to the increased prescription of fluoroquinolones and conjugative plasmid mediated horizontal transfer.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"90-97"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reference interval of Hemoglobin: Findings from a Cross Sectional Study in Adult Population of Dhaka, Bangladesh.","authors":"S Bhowmik, Q S Akhter, R Ahmed, J N Saha","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hemoglobin is a common hematological parameter assessed in laboratory and also an important tool for clinical management of patients. Reference values being used in most laboratories in our country, have been provided from the established reference values of developed countries. Hemoglobin concentration varies usually due to age, sex, attitude, ethnic origin, dietary habits, socioeconomic status and environmental factor. Therefore, there is a need to establish reference value of hemoglobin for healthy Bangladeshi population. This study was carried out to establish the reference value of hemoglobin of healthy adult population of Dhaka, Bangladesh. This cross sectional study was conducted in the department of Physiology, Dhaka Medical College, Dhaka, Bangladesh from July 2017 to June 2018. A total number of 500 healthy subjects from different areas of Dhaka city were selected on the basis of inclusion and exclusion criteria. The subject was interviewed and detailed history was taken and recorded in a prefixed questionnaire. Hemoglobin concentration was estimated in the Department of Laboratory Medicine, Dhaka Medical College hospital, Dhaka. For statistical analysis, Unpaired Student's 't' test was performed by using SPSS windows version 19.0. The reference values (2.5th percentile- 95th percentile) of hemoglobin concentration for male and female were 10.9-15.9 and 9.4-14.7gm/dl respectively. The hemoglobin concentration was significantly higher in male than female (p<0.05). There was no statistically significant correlation of hemoglobin concentration with age of study subjects. The reference value of hemoglobin obtained from this study is lower than practiced reference value and supports the need for nationwide study to establish our population specific hematological parameters.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"129-132"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Socio-Demographic Characteristics, Clinical Presentations and Treatment Outcome of RT-PCR Positive Covid-19 Patients of Mymensingh Region.","authors":"M S Hasan, S K Paul, S A Nasreen, N Haque, M K Khan, Z Haque","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Coronavirus disease-2019 (Covid-19) caused by the virus SARS-CoV 2 is a major health problem across the globe currently. Bangladesh is also defying this highly infectious disease with an exponentially rising number of cases across the country. This study was designed to observe the socio-demographic characteristics, clinical presentation and treatment outcome of Covid-19 cases in Bangladesh. In this cross-sectional observational study, a total of 334 Covid-19 positive patients were enrolled following selection criteria who were tested RT-PCR for Covid-19 infection in the Department of Microbiology, Mymensingh Medical College, Bangladesh from January 2021 to December 2021. A telephonic interview with a pre-tested semi-structured questionnaire was used to collect data. Among 334 Covid-19 positive patients, males (72.46%) were more affected than females (27.54%). The mean age was 36.32±12.369 years. Most of the cases resided in urban areas (83.53%). Approximately 13.77% were asymptomatic and 86.23% were symptomatic. Out of 334 patients, 98 (29.34%) patients had comorbidities, among which 76(22.75%) patients had a single co-morbid condition and 22(6.59%) patients had multiple comorbidities. Fever (83.53%), cough (52.99%) and altered smell and taste (40.71%) were the most common presenting symptoms. Antibiotics (91.32%) and paracetamol (83.53%) were the most commonly used drugs. Approximately 80.24% were isolated in their homes, while 5.39% were treated at Covid-19-dedicated hospitals. Finally, 13.77% were discharged without complications and 2.69% died. This investigation revealed that males became more infected than females. The majority of the cases resided in urban areas. Most of the infected patients were isolated at homes, whereas one-fifth of them were treated at different types of hospitals. Clinically, antibiotics were the most commonly used medication. However, the majority of the cases were discharged from the hospital without complications.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"227-233"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Saphenous Nerve Sensory Assessment in CABG Patients with Great Saphenous Vein Grafts: A Pre and Post Operative Study.","authors":"H Antony, S Chouhan, R Singh, S Wakode, Y Niwariya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To assess and compare the sensory component of the saphenous nerve in Coronary artery disease (CAD) patients undergoing Coronary artery bypass graft (CABG) with great saphenous vein graft pre and post-CABG. An observational longitudinal study evaluating the effect of surgery on the saphenous nerve involved 32 CAD patients undergoing CABG. This study was carried out jointly by the Department of Physiology and the Department of Cardiothoracic Vascular Surgery (CTVS) at All India Institute of Medical Sciences, Bhopal, India from November 2022 to January 2024. We performed pre- and post-operative sensory saphenous nerve conduction investigations and then examined their results to look for any alterations in the saphenous nerve following surgery. The average nerve latency of the Saphenous Nerve (Sensory) showed an increase from a minimum of 3.77 milliseconds to a maximum of 5.15 milliseconds, amplitude increased from a minimum of 12.04 microvolt at the pre-operative time point to a maximum of 12.15 microvolt, and conduction velocity of the nerve of harvested side limb decreased from a maximum of 54.28m/s from the the pre-operative value to a minimum of 35.61m/s. These results indicate that the saphenous nerve has sensory changes following CABG surgery. The increased Latency and decreased conduction velocity suggest a temporary or potentially longer-term impairment in nerve function. Despite the minor increase in amplitude, the overall decline in conduction velocity underscores the need for further research into the long-term impact of CABG with GSV grafts on saphenous nerve function and potential strategies for mitigating these effects.</p>","PeriodicalId":94148,"journal":{"name":"Mymensingh medical journal : MMJ","volume":"34 1","pages":"243-249"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}