Minerva medicaPub Date : 2025-02-01Epub Date: 2024-08-05DOI: 10.23736/S0026-4806.24.09286-3
Johannes Burtscher, Hannes Gatterer, David Niederseer, Karin Vonbank, Martin Burtscher
{"title":"Flying to high-altitude destinations.","authors":"Johannes Burtscher, Hannes Gatterer, David Niederseer, Karin Vonbank, Martin Burtscher","doi":"10.23736/S0026-4806.24.09286-3","DOIUrl":"10.23736/S0026-4806.24.09286-3","url":null,"abstract":"<p><p>Every year millions of people fly to high-altitude destinations. They thereby expose themselves to specific high-altitude conditions. The hypoxic environment (low ambient oxygen availability) constitutes a major factor affecting health and well-being at high altitude. While the oxygen availability is already moderately reduced inside the aircraft cabin, this reduction becomes aggravated when leaving the plane at high-altitude destinations. Especially if not pre-acclimatized, the risk of suffering from high-altitude illnesses, e.g., acute mountain sickness, high-altitude cerebral or pulmonary edema, increases with the level of altitude. In addition, diminished oxygen availability impairs exercise tolerance, which not only limits physical activity at high altitude but may also provoke symptomatic exacerbation of pre-existing diseases. Moreover, the cold and dry ambient air and increased levels of solar radiation may contribute to adverse health effects at higher altitude. Thus, medical pre-examination and pre-flight advice, and proper preparation (pre-acclimatization, exercise training, and potentially adaptation of pharmacological regimes) are of utmost importance to reduce negative health impacts and frustrating travel experiences.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"43-61"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2025-02-01Epub Date: 2024-05-14DOI: 10.23736/S0026-4806.24.09262-0
Carle Paul, Alexander J Stratigos, Tamar Nijsten, Paolo Gisondi, Carmen Salavastru, Martin Röecken, Charles Taieb, Francesca Sampogna, Myrto Trakatelli, Luis Puig, Marie A Richard
{"title":"The \"Burden of Skin Diseases\" Project: a population-based study on 44,689 participants from 27 European countries.","authors":"Carle Paul, Alexander J Stratigos, Tamar Nijsten, Paolo Gisondi, Carmen Salavastru, Martin Röecken, Charles Taieb, Francesca Sampogna, Myrto Trakatelli, Luis Puig, Marie A Richard","doi":"10.23736/S0026-4806.24.09262-0","DOIUrl":"10.23736/S0026-4806.24.09262-0","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"81-83"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140924115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reliability and validity of the Italian version of the Caregiver Priorities and Child Health Index of Life with Disabilities in children with cerebral palsy.","authors":"Federica Giorgi, Nicolò Sproccati, Corrado Zenesini, Francesca R Pulvirenti, Nicoletta Battisti, Nadia Sommella, Alessandra Feliciangeli, Antonella Cersosimo","doi":"10.23736/S0026-4806.24.09537-5","DOIUrl":"10.23736/S0026-4806.24.09537-5","url":null,"abstract":"<p><strong>Background: </strong>The Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD™) questionnaire is a reliable indirect indicator of functional, health status and quality of life in children with severe Cerebral Palsy (CP), as well as the caregiving burden. The aim of the study is to validate the Italian translation of Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD™) questionnaire and assess its reliability and validity.</p><p><strong>Methods: </strong>A cross-sectional study was conducted. The study involved 60 caregivers of children with CP, classified according to the Gross Motor Function Classification System (GMFCS) levels I-V. There was a self-compilation of the CPCHILD™ by primary caregivers during the clinical visit and a re-administration of the questionnaire 2-3 weeks after the first to a defined sample (N.=30, GMFCS IV-V). The Italian version of CPCHILD™'s psychometric properties were evaluated through internal consistency, test-retest reliability, and validity analyses.</p><p><strong>Results: </strong>The translated CPCHILD™ questionnaire showed excellent test-retest reliability (Intraclass Correlation Coefficient - ICC=0.97) across most sections, with significant construct validity, differentiating well between the various GMFCS levels. The internal consistency was robust (Cronbach's alpha=0.852) except for the health section. The face validity indicated high relevance of the questionnaire items to the caregivers, particularly in emotional well-being and social interaction.</p><p><strong>Conclusions: </strong>The Italian version of CPCHILD™ questionnaire is a reliable and valid tool for assessing the quality of life in children with severe CP, offering insights into the care burden and health status impacts perceived by caregivers.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"22-30"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142735446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploring the language of chronic pain stories through a Facebook page. A qualitative study on narratives and unmet needs.","authors":"Maria Giulia Marini, Alessandro Braga, Chiara Lattuada, Antonietta Cappuccio, Fabio Bianco Madau","doi":"10.23736/S0026-4806.24.09577-6","DOIUrl":"10.23736/S0026-4806.24.09577-6","url":null,"abstract":"<p><strong>Background: </strong>Dimensione Sollievo (Dimension of Relief) and its Facebook page represent a patient-centered social media initiative focused on chronic pain. This platform provides users with accurate resources on chronic pain and offers a virtual space for peer interaction - a crucial aspect for a condition often lacking proper recognition. The study's primary objective was to analyze the content in relation to unmet needs, with a secondary objective to explore the role of narrative medicine (NM) in this form of social communication.</p><p><strong>Methods: </strong>Posts, replies, and comments from the Facebook page between 2020 and 2023 were analyzed using thematic frameworks such as Frank, Kleinmann, Launer classifications, and Berne's transactional analysis. Language styles, semantics, word frequency, and metaphors were also examined. Narratives were analyzed through Nvivo software and Microsoft Office tools.</p><p><strong>Results: </strong>Users embraced the Facebook page as a safe space for interaction, where they found understanding and connection, unlike their experiences outside the community. While interactions were generally brief, they intensified around issues where users perceived injustices, such as the lack of recognition of their condition by medical professionals and family, and challenges in accessing benefits. Thematic analysis revealed that the most prominent theme was the dimension of disease, with many narratives expressing difficulty coping and a lack of progress.</p><p><strong>Conclusions: </strong>The application of narrative medicine (NM) tools highlights both explicit and unconscious patient needs, such as the desire to be heard and acknowledged. This study is the first to explore NM's potential in chronic pain. Implementing NM tools through informed moderation could transform pain management culture, improving treatment approaches and enhancing the overall community experience.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":"116 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction to: Sublingual sufentanil tablet system for postoperative analgesia after gynecological surgery.","authors":"Yigal Leykin, Alessandro Laudani, Nicola Busetto, Gabriele Chersini, Luca F Lorini, Dario Bugada","doi":"10.23736/S0026-4806.24.09671-X","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09671-X","url":null,"abstract":"<p><p>This article was published in Volume 110 issue 3 with a mistake in the text, on page 209, when specifying the period of patient recruitment. The correct sentence is: All patients were recruited in two hospitals: Santa Maria degli Angeli (Pordenone, Italy) and Papa Giovanni XXIII (Bergamo, Italy), between July 2016 and March 2017.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":"116 1","pages":"87"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143451319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-12-20DOI: 10.23736/S0026-4806.24.09597-1
Francesco Gavelli, Mattia Bellan, Filippo Patrucco
{"title":"Hemoptysis of unknown origin: let's put in order the puzzle pieces.","authors":"Francesco Gavelli, Mattia Bellan, Filippo Patrucco","doi":"10.23736/S0026-4806.24.09597-1","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09597-1","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-12-06DOI: 10.23736/S0026-4806.24.09264-4
Si Wang, Sheyu Li
{"title":"Type 2 diabetes, heart failure and the treatment of their comorbidity.","authors":"Si Wang, Sheyu Li","doi":"10.23736/S0026-4806.24.09264-4","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09264-4","url":null,"abstract":"<p><p>Both heart failure and type 2 diabetes are prevalent conditions and share similar pathogenesis, risk factors, and treatment medications. This review aims to inform clinical practice by summarizing the interaction between heart failure and type 2 diabetes, as well as the medications used to manage them. Novel medications such as Sodium-glucose cotransporter 2 (SGLT2) inhibitors, glucagon-likepeptide-1 receptor agonists, and finerenone have been shown to protect patients with type 2 diabetes from hospitalization for heart failure. SGLT2 inhibitors have also proven effective in patients with heart failure, regardless of the presence of type 2 diabetes. When choosing diabetes treatment medications for patients with heart failure and type 2 diabetes, shared decision-making can be helpful in weighing the benefits and harms based on individual scenarios. The selection of guideline-directed medical therapy aligns with patients without type 2 diabetes. Given the rapid evolution of knowledge in this field, clinicians need to stay updated with the latest evidence to provide optimal medical care.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnosis and treatment of periorbital and orbital cellulitis in children.","authors":"Xing Zhang, Chen Wang, Haixia Liu, Lulin Bi, Shuxin Wen","doi":"10.23736/S0026-4806.24.09357-1","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09357-1","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-12-01Epub Date: 2024-07-17DOI: 10.23736/S0026-4806.24.09112-2
Elvia Battaglia, Elena Compalati, Luca Mapelli, Agata Lax, Paola Pierucci, Paolo Solidoro, Paolo Banfi
{"title":"Pulmonary hypertension in patients affected by sleep-related breathing disorders: up to date from the literature.","authors":"Elvia Battaglia, Elena Compalati, Luca Mapelli, Agata Lax, Paola Pierucci, Paolo Solidoro, Paolo Banfi","doi":"10.23736/S0026-4806.24.09112-2","DOIUrl":"10.23736/S0026-4806.24.09112-2","url":null,"abstract":"<p><p>Sleep-related breathing disorders (SBD) are conditions of abnormal and difficult respiration during sleep, including chronic snoring, obstructive sleep apnea (OSA), central sleep apnea (CSA), sleep-related hypoventilation disorders and sleep-related hypoxemia. Some of them have a limited impact on health, but others (e.g., OSA) can have serious consequences, because of their dangerous effects on sleep and the hematic balance of oxygen and carbon dioxide. According to several population-based studies, prevalence of OSA is relatively high, approximately 3-7% for adult males and 2-5% for adult females in the general population. However, methodological differences and difficulties in characterizing this syndrome yielded to variability in estimates. Moreover, it is estimated that only about 40% of patients with OSA are diagnosed, which can lead to underestimation of disease prevalence. OSA is directly correlated with age and male sex and to risk factors such as obesity. Several studies found that OSA is associated with an increased risk of diabetes, some cancer types, cardiovascular and cerebrovascular diseases, such as hypertension, coronary artery disease and stroke. Pulmonary hypertension (PH), a noted cardiovascular disease, is significantly associated with sleep-related breathing disorders and lot of scientific studies published in the literature demonstrated a strong link between these conditions and the development of pulmonary hypertension PH. PH is relatively less common than sleep-related breathing disorders. The purpose of this systematic review is to analyze both the current knowledge around the consequences that SBD may have on pulmonary hemodynamics and the effects resulting from pharmacological and non-pharmacological treatments of SDB on PH.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"671-688"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141629660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}