Minerva medica最新文献_第3页

Translation, cross-cultural adaptation, and validation of the Italian version of the Parkinson's disease caregiver burden questionnaire (PDCB-I). 意大利语版帕金森病护理者负担问卷 (PDCB-I) 的翻译、跨文化改编和验证。

Minerva medica Pub Date : 2024-09-18 DOI: 10.23736/S0026-4806.24.09494-1

Sara Gherardini, Elena Porri, Matilde Dugini, Valentina Santoro, Matteo Paci

{"title":"Translation, cross-cultural adaptation, and validation of the Italian version of the Parkinson's disease caregiver burden questionnaire (PDCB-I).","authors":"Sara Gherardini, Elena Porri, Matilde Dugini, Valentina Santoro, Matteo Paci","doi":"10.23736/S0026-4806.24.09494-1","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09494-1","url":null,"abstract":"Background: To translate and cross-culturally adapt the Parkinson's Disease Caregiver Burden questionnaire (PDBC) into Italian language and to evaluate the psychometric properties of the Italian version in terms of test-retest reliability, internal consistency, and construct validity.Methods: The PDBC-I was developed by forward-backward translation to establish correspondence with the original English latest version. Psychometric properties were estimated in a sample of primary caregivers of individuals with Parkinson's disease. Reliability testing included internal consistency (Cronbach's alpha), test-retest reliability (ICC), the standard error of measurement (SEM) and the minimal detectable change (MDC), also expressed as percentage (MDC%). Validity was estimated by comparing the PDBC -I to the Caregiver Burden Inventory (CBI) and the Short Form 36 (SF-36) (Pearson correlation coefficient).Results: The questionnaire was administered to 65 caregivers, showing internal consistency of 0.934. ICC value was 0.811 (95% CI 0.708-0.880) for test-retest reliability, and the SEM and the MDC (MDC%) were 5.04 and 13.97 (38.21%), respectively. Low to moderate correlation with all other investigated scales (CBI: r=0.693; SF-36 physical score: r=-0.309; SF-36 mental score: r=-0.588; SF36 total score: -0.470) were found.Conclusions: Despite the PDCB-I holds acceptable psychometric properties to be used in clinical settings of Italian-speaking Countries as a measure of caregiver burden in caregivers of individuals with Parkinson Disease, the caregiver might require the support of a clinician to finalize the compilation of the questionnaire.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the therapeutic effect of Qishen Qiangxin formula combined with Sacubitril Valsartan sodium tablets on patients with chronic heart failure. 芪参羌活方联合沙库比特利缬沙坦钠片对慢性心力衰竭患者的治疗效果研究。

Minerva medica Pub Date : 2024-09-18 DOI: 10.23736/S0026-4806.24.09478-3

Ru He, Yuepeng Yuan, Yang Bai, Dong Li

引用次数: 0

Potassium thiocyanate poisoning treated by multidisciplinary collaboration. 多学科合作治疗硫氰酸钾中毒。

Minerva medica Pub Date : 2024-09-16 DOI: 10.23736/S0026-4806.24.09233-4

Fan Zhang, Jinxia Jiang

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Correlation between tryptophan and severity of coronary heart disease and clinical prognosis in elderly patients. 色氨酸与老年冠心病严重程度和临床预后的相关性。

Minerva medica Pub Date : 2024-09-16 DOI: 10.23736/S0026-4806.24.09158-4

Qing Yang, Ruiqing Zhu, Wangliang Zhu

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A unicentric hyaline vascular type of Castleman disease of lymph node: a study report and bioinformatics analysis-based GEO. 单中心透明血管型淋巴结卡斯特曼病：研究报告和基于 GEO 的生物信息学分析。

Minerva medica Pub Date : 2024-09-16 DOI: 10.23736/S0026-4806.24.09389-3

Tongxing Cui, Li Zhang, Wenqin Wang

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Predictive value of OGTT detection in early pregnancy for gestational diabetes mellitus. 妊娠早期 OGTT 检测对妊娠糖尿病的预测价值。

Minerva medica Pub Date : 2024-09-16 DOI: 10.23736/S0026-4806.24.09383-2

Bangwu Chen, Biao Xie, Shi Zhang

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Noninvasive tools for the assessment of fibrosis in metabolic dysfunction-associated steatotic liver disease. 评估代谢功能障碍相关脂肪性肝病纤维化的无创工具。

Minerva medica Pub Date : 2024-09-16 DOI: 10.23736/S0026-4806.24.09290-5

Joana Rigor, Maria E Martins, Beatriz Passos, Raquel Oliveira, Daniela Martins-Mendes

{"title":"Noninvasive tools for the assessment of fibrosis in metabolic dysfunction-associated steatotic liver disease.","authors":"Joana Rigor, Maria E Martins, Beatriz Passos, Raquel Oliveira, Daniela Martins-Mendes","doi":"10.23736/S0026-4806.24.09290-5","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09290-5","url":null,"abstract":"Metabolic dysfunction-associated steatotic liver disease (MASLD), previously nonalcoholic fatty liver disease (NAFLD), is the number one chronic liver disorder worldwide. Progression to advanced fibrosis marks the emergence of a significant risk of liver-related negative outcomes. However, only a minority of patients will present at this stage. Since widespread liver biopsy in unfeasible at such high disease prevalence, there was a need to develop noninvasive tests (NITs) that could easily and reliably be applied to patients with MASLD, regardless of clinical setting. The NITs include simple scores, like the fibrosis-4 (FIB-4) Index, patented serum tests, like the Enhanced Liver Fibrosis test (ELF™), and imaging-based modalities, like the vibration-controlled transient elastography (VCTE). Guidelines suggests a stepwise approach that utilizes more than one NIT, with FIB-4 <1.30 being used as a first step to rule out patients that do not need further testing. Subsequent choice of NIT will be influenced by setting, cost, and local availability. While these NITs are accurate, they are not perfect. As such, research is ongoing. A promising avenue is that of omics, a group of technologies that provide concomitant results on a large number of molecules (and other variables). With the advance of artificial intelligence, new NITs may arise from large demographic, biochemical, and radiological data sets.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142305098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The improvement of clinical effect of Chinese medicine directed transmission on patients with endometritis. 中药导引输液对子宫内膜炎患者临床疗效的改善。

Minerva medica Pub Date : 2024-09-05 DOI: 10.23736/S0026-4806.24.09305-4

Lixue Feng, Lingjuan Song, Xiuqin Zhang

引用次数: 0

Application of auricular point therapy in multi-mode postoperative analgesia after osteotomy and orthopedic surgery of lower limbs. 耳穴疗法在下肢截骨和矫形手术后多模式术后镇痛中的应用。

Minerva medica Pub Date : 2024-09-05 DOI: 10.23736/S0026-4806.24.09366-2

Xiang Wang, Maoxi Chen, Jie Li, Guoying Wang, Daobo Xing

引用次数: 0

Adenosine triphosphate: a new player in complex regional pain syndrome type 1. 三磷酸腺苷：1 型复杂性区域疼痛综合征的新角色。

Minerva medica Pub Date : 2024-08-05 DOI: 10.23736/S0026-4806.24.09345-5

Sergio Rosini, Stefano Rosini, Gianantonio Saviola, Luigi Molfetta

{"title":"Adenosine triphosphate: a new player in complex regional pain syndrome type 1.","authors":"Sergio Rosini, Stefano Rosini, Gianantonio Saviola, Luigi Molfetta","doi":"10.23736/S0026-4806.24.09345-5","DOIUrl":"https://doi.org/10.23736/S0026-4806.24.09345-5","url":null,"abstract":"The complex regional pain syndrome type 1 (CRPS-1) is one of the most discussed painful syndromes due to the variability and severity of its symptoms. CRPS-1 generally occurs after a trauma, a fracture or a sprain followed by an immobilization. Classical diagnostic criteria are not always clear; hence, the diagnosis is difficult. The definition of CRPS itself defines and considers the pain as key symptom neglecting the bone damage. Early CRPS involves the activation of the innate cutaneous immune system with altered sensory and sympathetic signaling, activation and proliferation of keratinocytes and mast cells in addition to the release of inflammatory mediators and pain. The role of the immune system and the response to the disease is becoming clearer as the microglia is activated as a result of injury and can induce a central sensitization while astrocytes can maintain the process. Adenosine triphosphate (ATP) exerts a fundamental role in the activation of innate cutaneous immune system, in the proliferation of keratinocytes and mast cells, in the release of several proinflammatory cytokines and in the microglia activation. It is essential to intervene on this pathology as soon as possible with drugs, as clodronate, able to reduce bone marrow edema and pain through the inhibition of the primary inflammatory process and the immune reaction, limiting the activation of macrophages and the release of cytokines activating nuclear growth factor (NGF). In this review the role of ATP, bisphosphonates and rehabilitation are discussed.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141891450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0