Minerva medicaPub Date : 2024-06-01Epub Date: 2023-11-14DOI: 10.23736/S0026-4806.23.08844-4
Jikai Meng, Jie Niu, Ning Zhang, Yongna Hao, Tieying Gao, Min Wei
{"title":"Modified conjunctival sac plasty and personalized eye model implantation in the treatment of patients with conjunctival sac stenosis and sunken eye socket.","authors":"Jikai Meng, Jie Niu, Ning Zhang, Yongna Hao, Tieying Gao, Min Wei","doi":"10.23736/S0026-4806.23.08844-4","DOIUrl":"10.23736/S0026-4806.23.08844-4","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"384-386"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"92158155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2024-05-09DOI: 10.23736/S0026-4806.24.09203-6
Fabio Caputo, Francesco Penitenti, Barbara Bergonzoni, Lisa Lungaro, Anna Costanzini, Giacomo Caio, Roberto DE Giorgio, Maria R Ambrosio, Giorgio Zoli, Gianni Testino
{"title":"Alcohol use disorders and liver fibrosis: an update.","authors":"Fabio Caputo, Francesco Penitenti, Barbara Bergonzoni, Lisa Lungaro, Anna Costanzini, Giacomo Caio, Roberto DE Giorgio, Maria R Ambrosio, Giorgio Zoli, Gianni Testino","doi":"10.23736/S0026-4806.24.09203-6","DOIUrl":"10.23736/S0026-4806.24.09203-6","url":null,"abstract":"<p><p>Alcoholic liver disease (ALD) is currently, worldwide, the second most common cause of human fatalities every year. Alcohol use disorders (AUDs) lead to 80% of hepatotoxic deaths, and about 40% of cases of cirrhosis are alcohol-related. An acceptable daily intake (ADI) of ethanol is hard to establish and studies somewhat controversially recommend a variety of dosages of ADI, whilst others regard any intake as dangerous. Steatohepatitis should be viewed as \"the rate limiting step\": generally, it can be overcome by abstinence, although in some patients, abstinence has little effect, with the risk of fibrosis, leading in some cases to hepatocellular carcinoma (HCC). Chronic alcoholism can also cause hypercortisolism, specifically pseudo-Cushing Syndrome, whose diagnosis is challenging. If fibrosis is spotted early, patients may be enrolled in detoxification programs to achieve abstinence. Treatment drugs include silybin, metadoxine and adenosyl methionine. Nutrition and the proper use of micronutrients are important, albeit often overlooked in ALD treatment. Other drugs, with promising antifibrotic effects, are now being studied. This review deals with the clinical and pathogenetic aspects of alcohol-related liver fibrosis and suggests possible future strategies to prevent cirrhosis.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"354-363"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2023-11-21DOI: 10.23736/S0026-4806.23.08899-7
Minyu Xiao
{"title":"Exploration of science education curriculum reform in kindergartens from the perspective of Anji Games in Jeollanam-do province.","authors":"Minyu Xiao","doi":"10.23736/S0026-4806.23.08899-7","DOIUrl":"10.23736/S0026-4806.23.08899-7","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"387-390"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138178363","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2024-01-29DOI: 10.23736/S0026-4806.23.08950-4
Haijuan Yuan, Jiannan Zhang, Hong Chen
{"title":"Evidence-based nursing in the prevention of central venous catheter-related bloodstream infections.","authors":"Haijuan Yuan, Jiannan Zhang, Hong Chen","doi":"10.23736/S0026-4806.23.08950-4","DOIUrl":"10.23736/S0026-4806.23.08950-4","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"392-395"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139577031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2024-04-24DOI: 10.23736/S0026-4806.24.09192-4
Michele Mondoni, Jacopo Cefalo, Paolo Carlucci, Mariangela Puci, Laura Saderi, Mauro Degrassi, Alfons Torrego Fernandez, Virginia Pajares, Uffe Bodtger, Claudio Sorino, Maria P Zagaria, Paolo Solidoro, Stefano Centanni, Giovanni Sotgiu
{"title":"The current practice in the diagnostic work-up of patients with hemoptysis of unknown etiology: an international survey.","authors":"Michele Mondoni, Jacopo Cefalo, Paolo Carlucci, Mariangela Puci, Laura Saderi, Mauro Degrassi, Alfons Torrego Fernandez, Virginia Pajares, Uffe Bodtger, Claudio Sorino, Maria P Zagaria, Paolo Solidoro, Stefano Centanni, Giovanni Sotgiu","doi":"10.23736/S0026-4806.24.09192-4","DOIUrl":"10.23736/S0026-4806.24.09192-4","url":null,"abstract":"<p><strong>Background: </strong>Hemoptysis is a challenging and potentially life-threatening medical condition. The most appropriate diagnostic work-up is debated and several diagnostic approaches are implemented worldwide.</p><p><strong>Methods: </strong>An international, online survey was carried out to investigate the current practice of the diagnostic work-up of patients with hemoptysis of unknown etiology.</p><p><strong>Results: </strong>Overall, 604 physicians responded to the survey. At baseline, chest X-ray was suggested as the first diagnostic investigation by 342 (56.6%) participants. Computed tomography (CT) was suggested in each patient with non- and life-threatening hemoptysis by 310 (51.3%) and 526 (87.1%) respondents, respectively. Contrast-enhanced CT is the currently preferred technique (333, 55.1%). In case of patchy ground glass opacities and negative CT, 287 (47.5%) and 222 (36.8%) participants, respectively, would always offer bronchoscopy. Otorhinolaryngological evaluation was mostly suggested in case of suspected upper airways bleeding before other investigations (212, 35.1%). A follow-up was recommended for idiopathic hemoptysis by the majority of the participants (316, 52.3%). A multidisciplinary assessment is deemed crucial for each patient with life-threatening hemoptysis (437, 72.4%).</p><p><strong>Conclusions: </strong>Chest X-ray and contrast-enhanced CT are currently preferred as the first diagnostic investigations, regardless of hemoptysis severity. Bronchoscopy is suggested in case of negative radiological examination and when CT shows only ground glass opacities. Otorhinolaryngological evaluation is advised before any other investigations when upper airways bleeding is suspected. Patients with idiopathic hemoptysis are suggested to undergo a clinical follow-up and in case of life-threatening bleeding a multidisciplinary assessment is deemed crucial. Due to the heterogeneous approaches a consensus statement would be needed.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"293-300"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140870520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2024-02-06DOI: 10.23736/S0026-4806.24.09169-9
Huibin Yao, Ying Liang, Yingjian Sha, Yongsheng Jia, Yehui Shi
{"title":"Usefulness of the coagulation indicators in predicting short and long disease-free interval in breast cancer and development of a nomogram.","authors":"Huibin Yao, Ying Liang, Yingjian Sha, Yongsheng Jia, Yehui Shi","doi":"10.23736/S0026-4806.24.09169-9","DOIUrl":"10.23736/S0026-4806.24.09169-9","url":null,"abstract":"","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"397-400"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva medicaPub Date : 2024-06-01Epub Date: 2024-05-09DOI: 10.23736/S0026-4806.24.09198-5
Nuria Puente, Pablo Solis, Jose A Riancho
{"title":"Genetic causes of hypophosphatemia.","authors":"Nuria Puente, Pablo Solis, Jose A Riancho","doi":"10.23736/S0026-4806.24.09198-5","DOIUrl":"10.23736/S0026-4806.24.09198-5","url":null,"abstract":"<p><p>Phosphate is a key component of mineralized tissues and is also part of many organic compounds. Phosphorus homeostasis depends especially upon intestinal absorption, and renal excretion, which are regulated by various hormones, such as PTH, 1,25-dihydroxyvitamin D, and fibroblast growth factor 23. In this review we provide an update of several genetic disorders that affect phosphate transporters through cell membranes or the phosphate-regulating hormones, and, consequently, result in hypophosphatemia.</p>","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"320-336"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}