Minerva medica最新文献_第10页

A case of rhabdomyosarcoma with perianal swelling and pain. 一例伴有肛周肿胀和疼痛的横纹肌肉瘤。

Minerva medica Pub Date : 2024-06-12 DOI: 10.23736/S0026-4806.24.09406-0

Shiwei Yang, Shanyu Gao, Tongming Liu, Junning Liu

引用次数: 0

Bioinformatics analysis of the prognostic value of ADH1B gene in diabetic foot ulcer. 糖尿病足溃疡 ADH1B 基因预后价值的生物信息学分析

Minerva medica Pub Date : 2024-06-05 DOI: 10.23736/S0026-4806.24.09367-4

Yifei Sun, Chunxiao Hu, Yongtao Su

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Effect of bronchoscopic alveolar lavage combined with methylprednisolone on ALT, LDH, MP-DNA and MP-lgM in children with severe mycoplasma pneumonia. 支气管镜肺泡灌洗联合甲基强的松龙对重症支原体肺炎患儿谷丙转氨酶（ALT）、低密度脂蛋白胆固醇（LDH）、MP-DNA 和 MP-lgM 的影响。

Minerva medica Pub Date : 2024-06-05 DOI: 10.23736/S0026-4806.24.09341-8

Baoju Shan, Ting Yang

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Effectiveness of the "Internet+" home nurse management model for elderly patients with chronic diseases. 互联网+"家庭护士管理模式对老年慢性病患者的疗效。

Minerva medica Pub Date : 2024-06-05 DOI: 10.23736/S0026-4806.24.09047-5

Qinghong Long, Jing Liu

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Renal hemodynamic monitoring-guided precision fluid therapy in patients with septic shock. 脓毒性休克患者在肾血流动力学监测指导下的精准输液治疗。

Minerva medica Pub Date : 2024-06-05 DOI: 10.23736/S0026-4806.24.09371-6

Ying Li, Wenbiao Xiao, Xiao Lin

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Relationship between serum CA125, TIMP-1 and SAA levels and clinicopathological characteristics and prognosis in patients with non-small cell lung cancer. 非小细胞肺癌患者血清 CA125、TIMP-1 和 SAA 水平与临床病理特征和预后的关系。

Minerva medica Pub Date : 2024-06-05 DOI: 10.23736/S0026-4806.24.09306-6

Xin Chen, Xiang He, Yuan Li, Bing Guo, Guangyu Chen

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Application of positive expiratory pressure therapeutic apparatus in pulmonary rehabilitation of patients with chronic obstructive pulmonary disease. 呼气正压治疗仪在慢性阻塞性肺病患者肺康复中的应用。

Minerva medica Pub Date : 2024-06-01 Epub Date: 2024-01-19 DOI: 10.23736/S0026-4806.23.09040-7

Sihui Zheng, Yanhong Wang

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Non-cardiac comorbidities in heart failure: an update on diagnostic and management strategies. 心力衰竭的非心脏并发症：诊断和管理策略的最新进展。

Minerva medica Pub Date : 2024-06-01 DOI: 10.23736/S0026-4806.24.09070-0

Nandan Kodur, W H Wilson Tang

{"title":"Non-cardiac comorbidities in heart failure: an update on diagnostic and management strategies.","authors":"Nandan Kodur, W H Wilson Tang","doi":"10.23736/S0026-4806.24.09070-0","DOIUrl":"10.23736/S0026-4806.24.09070-0","url":null,"abstract":"Managing non-cardiac comorbidities in heart failure (HF) requires a tailored approach that addresses each patient's specific conditions and needs. Regular communication and coordination among healthcare providers is crucial to providing the best possible care for these patients. Poorly controlled hypertension contributes to left ventricular remodeling and diastolic dysfunction, emphasizing the importance of optimal blood pressure control while avoiding adverse effects. Among HF patients with diabetes, SGLT2 inhibitors and mineralocorticoid receptor antagonists have shown promise in reducing HF-related morbidity and mortality. Chronic kidney disease exacerbates HF and vice versa, forming the vicious cardiorenal syndrome, so disease-modifying therapies should be maintained in HF patients with comorbid CKD, even with transient changes in kidney function. Anemia in HF patients may be multifactorial, and there is growing evidence for the benefit of intravenous iron supplementation in HF patients with iron deficiency with or without anemia. Obesity, although a risk factor for HF, paradoxically offers a better prognosis once HF is established, though developing treatment strategies may improve symptoms and cardiac performance. In HF patients with stroke and atrial fibrillation, anticoagulation therapy is recommended. Among HF patients with sleep-disordered breathing, continuous positive airway pressure may improve sleep quality. Chronic obstructive pulmonary disease often coexists with HF, and many patients can tolerate cardioselective beta-blockers. Cancer patients with comorbid HF require careful consideration of cardiotoxicity risks associated with cancer therapies. Depression is underdiagnosed in HF patients and significantly impacts prognosis. Cognitive impairment is prevalent in HF patients and impacts their self-care and overall quality of life.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":"115 3","pages":"337-353"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impaired endogenous fibrinolysis status: a potential prognostic predictor in ischemic stroke. 内源性纤溶状态受损：缺血性脑卒中的潜在预后预测因素。

Minerva medica Pub Date : 2024-06-01 Epub Date: 2024-05-09 DOI: 10.23736/S0026-4806.24.09133-X

Yang Chen, Ying Gue, Garry McDowell, Diana A Gorog, Gregory Y H Lip

{"title":"Impaired endogenous fibrinolysis status: a potential prognostic predictor in ischemic stroke.","authors":"Yang Chen, Ying Gue, Garry McDowell, Diana A Gorog, Gregory Y H Lip","doi":"10.23736/S0026-4806.24.09133-X","DOIUrl":"10.23736/S0026-4806.24.09133-X","url":null,"abstract":"Stroke confers a severe global healthcare burden, hence exploring risk factors for stroke occurrence and prognosis is important for stroke prevention and post-stroke management strategies. Endogenous fibrinolysis is a spontaneous physiological protective mechanism that dissolves thrombus to maintain vascular patency. Recently, impaired endogenous fibrinolysis has been considered as a potential novel cardiovascular risk factor, but its link with ischaemic stroke in the past has been underappreciated. In this review, we summarize the latest mechanisms of endogenous fibrinolysis, review the current evidence and data on endogenous fibrinolysis in ischemic stroke. It includes the structure of thrombus in ischemic stroke patients, the effect of fibrin structure on the endogenous fibrinolytic efficiency, and the association between intravenous thrombolytic therapy and endogenous fibrinolysis in ischemic stroke. It also includes the single factors (tissue plasminogen activator, urokinase plasminogen activator, plasminogen activator inhibitor-1, thrombin activatable fibrinolysis inhibitor, complement component 3, complement component 5, alpha-2-antiplasmin, plasmin-alpha-2-antiplasmin complex, and lipoprotein[a]), and the global assessments of endogenous fibrinolysis status (thromboelastography, rotational thromboelastometry, and global thrombosis test), and their potential as predictors to identify occurrence or unfavorable functional outcomes of ischemic stroke. All of these assessments present advantages and limitations, and we suggest that the global thrombosis test may be more appropriate for detecting impaired endogenous fibrinolysis status in ischemic stroke patients.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"364-379"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Educational status and the risk of adverse outcomes in Asian patients with atrial fibrillation: a report from the prospective APHRS-AF Registry. 亚洲心房颤动患者的教育状况与不良后果风险：来自前瞻性 APHRS-AF 登记处的报告。

Minerva medica Pub Date : 2024-06-01 Epub Date: 2024-05-09 DOI: 10.23736/S0026-4806.24.09159-6

Tommaso Bucci, Giulio F Romiti, Bernadette Corica, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Hung-Fat Tse, Marco Proietti, Tze-Fan Chao, Gregory Y H Lip

{"title":"Educational status and the risk of adverse outcomes in Asian patients with atrial fibrillation: a report from the prospective APHRS-AF Registry.","authors":"Tommaso Bucci, Giulio F Romiti, Bernadette Corica, Alena Shantsila, Wee-Siong Teo, Hyung-Wook Park, Wataru Shimizu, Hung-Fat Tse, Marco Proietti, Tze-Fan Chao, Gregory Y H Lip","doi":"10.23736/S0026-4806.24.09159-6","DOIUrl":"10.23736/S0026-4806.24.09159-6","url":null,"abstract":"Background: The aim of this study was to evaluate the impact of educational status (ES) on the clinical course of Asian patients with atrial fibrillation (AF).Methods: We used data from the prospective APHRS-AF Registry. ES was classified as follows: low (primary school), medium (secondary), and high (University). The primary outcome was a composite of all-cause death, thromboembolic events, acute coronary syndrome, and heart failure. Secondary outcomes were each component of the primary outcome, cardiovascular death, and major bleeding. The one-year risk of primary and secondary outcomes was assessed through Cox-regressions. Adherence to the Atrial fibrillation Better Care (ABC) pathway was assessed.Results: Among 2697 AF patients (69±12 years, 34.8% females), 34.6% had low ES; 37.3% had medium ES; and 28.1% had high ES. Compared to patients with medium-high ES, patients with low ES were older, more often females, with a higher prevalence of cardiovascular risk factors, and a lower ABC pathway adherence (30.4% vs. 40.2%, P<0.001). On multivariable analysis, low ES was associated with a higher risk for the primary outcome (HR 1.52,95%CI 1.11-2.06) and all-cause death (HR 1.76,95%CI 1.10-2.83) than medium-high ES. A significant interaction was found for the risk of composite outcome among the different age strata, with the higher risk in the elderly (P for int=0.008), whereas the beneficial effect of the ABC pathway was irrespective of ES (P for int=0.691).Conclusions: In Asian AF patients, low ES is associated with high mortality. Efforts to improve education and include ES evaluation in the integrated care approach for AF are necessary to reduce the cardiovascular burden in these patients.","PeriodicalId":94143,"journal":{"name":"Minerva medica","volume":" ","pages":"308-319"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140900735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0