Minerva gastroenterology最新文献_第3页

The real-time analysis of gastric juice (Endofaster) for detection of Helicobacter Pylori: a reliable tool in substitution of histology. 实时分析胃液（Endofaster）检测幽门螺旋杆菌：替代组织学的可靠工具。

IF 1.9

Minerva gastroenterology Pub Date : 2024-09-01 Epub Date: 2024-03-26 DOI: 10.23736/S2724-5985.23.03480-0

Maria C Conti Bellocchi, Enrico Gasparini, Serena DI Stefano, Valentina Bobba, Laura Bernardoni, Viola Fino, Stefano F Crinò, Armando Gabbrielli

{"title":"The real-time analysis of gastric juice (Endofaster) for detection of Helicobacter Pylori: a reliable tool in substitution of histology.","authors":"Maria C Conti Bellocchi, Enrico Gasparini, Serena DI Stefano, Valentina Bobba, Laura Bernardoni, Viola Fino, Stefano F Crinò, Armando Gabbrielli","doi":"10.23736/S2724-5985.23.03480-0","DOIUrl":"10.23736/S2724-5985.23.03480-0","url":null,"abstract":"Background: EndoFaster perform gastric juice analysis providing real-time Helicobacter pylori (HP) diagnosis during esophagogastroduodenoscopy (EGD), based on ammonium level. We aimed to assess its accuracy in detecting HP infection compared to the paired histology and to establish the optimum ammonium concentration cut-off point (COP).Methods: Consecutive adult outpatients referred for EGD were prospectively enrolled between December 2021 and March 2022. In-patients, those with surgically altered anatomy, suspected neoplasia, and bleeding were excluded. EndoFaster and histology were performed in all patients, with additional stool antigen test (SAT) reserved for discordant cases. EndoFaster diagnostic measures were calculated, and ammonium level COP established using AUROC curve analysis.Results: 101 patients (64 female, mean age 56.7±16.1 years) were included. HP infection was diagnosed in 35 (34.6%) and 15 (14.8%) patients by EndoFaster and histology, respectively. Diagnostic accuracy in comparison with histology was 77.8% (95%CI 68.3% - 85.5%). After implementing SAT for gold standard assessment, EndoFaster accuracy increased to 81.6% (95%CI 72.5%-88.7%). AUROC curve (0.93±0.03, 95%CI 0.86-0.99) identified an ammonium COP of ≥67.5ppm. Using the new COP, EndoFaster accuracy further increased to 88.8% (95%CI 80.8%-94.2%).Conclusions: Endofaster showed high accuracy for HP detection, with moderate agreement to histology. An ammonium COP of 67.5 ppm seems to be the threshold with the highest accuracy for HP detection.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"315-321"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application analysis of enteral immune nutritional support in postoperative radiotherapy and chemotherapy patients with colorectal cancer. 肠内免疫营养支持在癌症术后放化疗中的应用分析。

IF 1.9

Minerva gastroenterology Pub Date : 2024-09-01 Epub Date: 2023-10-27 DOI: 10.23736/S2724-5985.23.03526-X

Zhongpeng Zhu, Yongsheng Li

引用次数: 0

Diagnostic accuracy of antiendomysial antibodies biopsy test for celiac disease in clinical practice. 抗endomysial抗体活组织检查在临床实践中对乳糜泻的诊断准确性。

IF 1.9

Minerva gastroenterology Pub Date : 2024-09-01 Epub Date: 2023-10-05 DOI: 10.23736/S2724-5985.23.03396-X

Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi

{"title":"Diagnostic accuracy of antiendomysial antibodies biopsy test for celiac disease in clinical practice.","authors":"Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi","doi":"10.23736/S2724-5985.23.03396-X","DOIUrl":"10.23736/S2724-5985.23.03396-X","url":null,"abstract":"Background: The diagnosis of celiac disease (CD) is still challenging and tests that show an activation of the immune system against gluten are required. IgA antiendomysial antibodies detection in the supernatant of intestinal biopsies by immunofluorescence technique (AEA-biopsy) is a promising diagnostic tool. The aim of the present study was to evaluate the diagnostic accuracy of AEA-biopsy in a pediatric population with suspected CD.Methods: All children who underwent upper gastrointestinal endoscopy at the Unit of Pediatrics of Treviso Hospital were enrolled and divided into 4 groups: classical CD, CD excluded, potential CD and control group. For each patient, serum autoantibodies and histological evaluation were determined. Two additional biopsy samples were taken to test for presence of AEA.Results: A total of 92 patients were enrolled. All the classical CD cases (38) had a positive AEA-biopsy. In the CD excluded group (10 in total) AEA-biopsy was negative in all patients except 1. Among potential CD patients (which were 14), AEA-biopsy was negative in 4. In the control group (30 patients) AEA-biopsy was negative in all patients except 1. The sensitivity and specificity of AEA-biopsy were 100% and 96% respectively.Conclusions: AEA-biopsy has an excellent diagnostic accuracy in a routine clinical setting.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"291-298"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the effect of PDCA nursing management on patient prevention complications and satisfaction after laser surgery in plastic and aesthetic clinics. PDCA护理管理对整形美容门诊激光手术患者预防并发症及满意度的影响分析。

IF 1.9

Minerva gastroenterology Pub Date : 2024-09-01 Epub Date: 2023-10-02 DOI: 10.23736/S2724-5985.23.03443-5

Chunyan Huang, Suping Lin, Shuhong Ge, Jingjing Xu

引用次数: 0

The effect and clinical application value of intestinal preparation self-assessment form on colonoscopy. 肠道准备自我评估表对结肠镜检查的影响及临床应用价值。

IF 1.9

Minerva gastroenterology Pub Date : 2024-07-02 DOI: 10.23736/S2724-5985.24.03697-0

Yingshuang Huang, Xiaoyan Yao, Jiayan Shen, Yining Gao, Guoping He, Shengpeng Geng

引用次数: 0

The diagnostic capability of i-scan for early gastric cancer detection: a systematic review and meta-analysis. i-scan 检测早期胃癌的诊断能力：系统综述和荟萃分析。

IF 1.9

Minerva gastroenterology Pub Date : 2024-06-26 DOI: 10.23736/S2724-5985.24.03702-1

Andrew Canakis, Kourosh Kalachi, Jay Bapaye, Nevin Varghese, Benjamin Twery, Jerrold S Canakis

{"title":"The diagnostic capability of i-scan for early gastric cancer detection: a systematic review and meta-analysis.","authors":"Andrew Canakis, Kourosh Kalachi, Jay Bapaye, Nevin Varghese, Benjamin Twery, Jerrold S Canakis","doi":"10.23736/S2724-5985.24.03702-1","DOIUrl":"https://doi.org/10.23736/S2724-5985.24.03702-1","url":null,"abstract":"Background: I-scan is an image enhancing technology that utilizes contrast, surface, and tone enhancement to examine the microvascular and microsurface structures of mucosa. Its ability to diagnosis GC is of growing interest due to its ability to make an optical diagnosis; however, only a handful of studies have explored its role in this setting. We aimed to investigate the diagnostic capability of i-scan for GC detection.Methods: Multiple databases were searched for studies utilizing i-scan for GC detection until February 2024. Primary outcomes included the pooled sensitivity, specificity, and accuracy.Results: Seven studies were included (371 patients, 220 GC lesions). The pooled sensitivity was 84% (four studies, 95% CI: 0.65; 0.93), specificity was 83% (three studies, 95% CI: 0.68; 0.92) and accuracy was 84% studies (N.=3, 95% CI: 0.69; 0.93).Conclusions: I-scan appears to be an effective diagnostic tool for GC. However, the functional capabilities related to brightness detection may limits use. Further prospective, comparative studies are needed to determine its role in clinical practice compared to white light endoscopy, narrow band imaging and chromoendoscopy.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141452541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthesiologist-directed care for elective gastrointestinal endoscopy: results of an Italian multicentric prospective observational study. 麻醉师指导下的择期胃肠道内窥镜检查：意大利多中心前瞻性观察研究的结果。

Minerva gastroenterology Pub Date : 2024-06-05 DOI: 10.23736/S2724-5985.24.03656-8

Mauro Manno, Giuliano F Bonura, Paola Soriani, Roberta Pileggi, Giovanni Aragona, Vincenzo Cennamo, Antonio Colecchia, Rita Conigliaro, Marco DI Marco, Carlo Fabbri, Lorenzo Fuccio, Rosa F LA Fortezza, Alberto Merighi, Alessandro Mussetto, Giorgio Nervi, Paolo Orsi, Romano Sassatelli, Rocco M Zagari, Paolo Biancheri

{"title":"Anesthesiologist-directed care for elective gastrointestinal endoscopy: results of an Italian multicentric prospective observational study.","authors":"Mauro Manno, Giuliano F Bonura, Paola Soriani, Roberta Pileggi, Giovanni Aragona, Vincenzo Cennamo, Antonio Colecchia, Rita Conigliaro, Marco DI Marco, Carlo Fabbri, Lorenzo Fuccio, Rosa F LA Fortezza, Alberto Merighi, Alessandro Mussetto, Giorgio Nervi, Paolo Orsi, Romano Sassatelli, Rocco M Zagari, Paolo Biancheri","doi":"10.23736/S2724-5985.24.03656-8","DOIUrl":"https://doi.org/10.23736/S2724-5985.24.03656-8","url":null,"abstract":"Background: Sedation, ranging from minimal, moderate and deep sedation to general anesthesia, improves patient comfort and procedure quality in gastrointestinal endoscopy (GIE). There are currently no comprehensive recommendations on sedation practice in diagnostic and therapeutic GIE. We aimed to investigate real-life sedation practice in elective GIE.Methods: We performed a multicentric observational study across 14 Endoscopy Units in Italy. We recorded consecutive data on all diagnostic procedures performed with Anesthesiologist-directed care (ADC) and all therapeutic procedures performed with ADC or non-Anesthesiologist sedation (NAS) over a three-month period.Results: Dedicated ADC is available five days/week in 28.6% (4/14), four days/week in 21.5% (3/14), three days/week in 35.7% (5/14), two days/week in 7.1% (1/14) and one day/week in 7.1% (1/14) of participating Centers. ADC use for elective diagnostic GIE varied from 18.2% to 75.1% of the total number of procedures performed with ADC among different Centers. ADC use for elective therapeutic GIE varied from 10.8% to 98.9% of the total number of elective therapeutic procedures performed among different Centers.Conclusions: Our study highlights the lack of standardization and consequent great variability in sedation practice for elective GIE, with ADC being potentially overused for diagnostic procedures and underused for complex therapeutic procedures. A collaborative effort involving Endoscopists, Anesthesiologist and Institutions is needed to optimize sedation practice in GIE.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Markedly raised CA 19-9 levels in an asymptomatic patient: the role of Helicobacter pylori infection. 无症状患者体内 CA 19-9 水平明显升高：幽门螺杆菌感染的作用。

Minerva gastroenterology Pub Date : 2024-06-05 DOI: 10.23736/S2724-5985.24.03704-5

Angelo D'Agruma, Leonardo D'Agruma, Pamela Piscitelli, Paola Parente, Paolo Graziano, Gianluigi Vendemiale, Marco Castori, Giovanni B Gasbarrini, Salvatore DE Cosmo, Antonio Mirijello

引用次数: 0

Probiotic mixture in patients after Helicobacter pylori eradication: a real-life experience. 幽门螺旋杆菌根除后患者的益生菌混合物：现实生活中的经验。

IF 1.9

Minerva gastroenterology Pub Date : 2024-06-01 Epub Date: 2024-03-26 DOI: 10.23736/S2724-5985.24.03634-9

Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi

{"title":"Probiotic mixture in patients after Helicobacter pylori eradication: a real-life experience.","authors":"Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi","doi":"10.23736/S2724-5985.24.03634-9","DOIUrl":"10.23736/S2724-5985.24.03634-9","url":null,"abstract":"Background: Eradication for Helicobacter pylori usually induces digestive dysbiosis that, in turn, elicits symptoms. Consequently, probiotic supplementation may counterbalance the disturbed microbiota after this procedure. So, probiotics may restore microbiota homeostasis quickly relieve complaints.Methods: The current study evaluated the efficacy and safety of Abivisor®, a food supplement containing Lacticaseibacillus rhamnosus LR06 (3 billion living cells), Lactiplantibacillus pentosus LPS01(100 million living cells), Lactiplantibacillus plantarum LP01 (1 billion living cells), and N-acetyl cysteine (60 mg). Patients were randomized into two groups (2:1). Group A took one stick/daily for 60 days after eradication. Group B was considered as control. Patients were evaluated at baseline (T0) and after 15 (T1), 30 (T2), and 60 (T3) days. The severity of digestive symptoms was measured by patients using a Visual Analog Scale. The percentage of patients with each symptom was also evaluated.Results: Abivisor® has significantly and progressively diminished intestinal symptoms' presence and severity at T1, T2, and even more at T3. Accordingly, the percentage of symptomatic patients diminished more rapidly and significantly in group A than in B. All patients well tolerated the food supplement.Conclusions: The present study suggests that Abivisor® may be an effective and safe therapeutic option for managing patients undergoing H. pylori eradication.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"197-207"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can a combination of probiotics and nutraceuticals help preventing the abemaciclib-related diarrhea in breast cancer patients? 益生菌和营养保健品的组合能帮助乳腺癌患者预防与阿贝昔单抗相关的腹泻吗？

IF 1.9

Minerva gastroenterology Pub Date : 2024-06-01 Epub Date: 2024-03-14 DOI: 10.23736/S2724-5985.24.03647-7

Umberto Pacetti, Francesco DI Pierro, Massimiliano Cazzaniga, Ilaria Cavecchia, Mariarosaria Matera, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Simonetta C Stani

引用次数: 0