Minerva gastroenterology最新文献_第7页

National frequency, trends, and healthcare burden of care fragmentation in readmissions for end-stage liver disease in the USA. 美国终末期肝病患者再入院治疗的全国频率、趋势和医疗保健负担。

Minerva gastroenterology Pub Date : 2023-12-01 DOI: 10.23736/S2724-5985.22.03232-6

Olufunso Agbalajobi, Ebehiwele Ebhohon, Chineye B Amuchi, Edwige C Nzugang, Elizabeth O Soladoye, Oyedotun Babajide, Adeyinka C Adejumo

{"title":"National frequency, trends, and healthcare burden of care fragmentation in readmissions for end-stage liver disease in the USA.","authors":"Olufunso Agbalajobi, Ebehiwele Ebhohon, Chineye B Amuchi, Edwige C Nzugang, Elizabeth O Soladoye, Oyedotun Babajide, Adeyinka C Adejumo","doi":"10.23736/S2724-5985.22.03232-6","DOIUrl":"10.23736/S2724-5985.22.03232-6","url":null,"abstract":"Background: End-stage liver disease (ESLD) patients have frequent readmissions to the same facility or a different hospital (care fragmentation). Care fragmentation results in care delivery from an unfamiliar clinical team or setting, a potential source of suboptimal clinical outcomes. We examined the occurrence, trends, and association between care fragmentation and outcomes during readmissions for ESLD.Methods: From the Nationwide Readmissions Database (January to September 2010-2014), we followed adult (age ≥18 years) hospitalizations for ESLD who were discharged alive for 90 days. During 30- and 90-day readmissions, we calculated the frequency, determinants, and clinical outcomes of care fragmentation (SAS 9.4).Results: Of the 67,480 ESLD hospitalizations surviving at discharge from 2010-2014, 35% (23,872) and 52% (35,549) were readmitted in 30- and 90-days respectively. During readmissions, the frequencies of care fragmentation were similar (30-day: 25.4% and 90-day: 25.8%) and remained stable from 2010 to 2014 (P trends>0.5). Similarly, factors associated with care fragmentation were consistent across 30- and 90-day readmissions. These included ages: 18-44 years, liver cancer, receipt of liver transplantation, hepatorenal syndrome, prolonged length of stay, and hospitalization in non-teaching facilities. During 30- and 90-day readmissions, care fragmentation was associated with higher risk of mortality (adjusted mean ratio: 1.13[1.03-1.24] and 1.14 [1.06-1.23]; P values<0.0001), prolonged length of stay (4.6-days vs. 4.1-days and 5.2-days vs. 4.6-days; P values<0.0001), and higher hospital charges ($36,884 vs. $28,932 and $37,354 vs. $30,851; P values<0.0001).Conclusions: Care fragmentation is high among readmissions for ESLD and is associated with poorer outcomes.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":"69 4","pages":"470-478"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of demographics in noninvasive testing for colorectal cancer screening: do targeted cut-off values improve detection? 人口统计学在结直肠癌筛查无创检测中的作用：有针对性的临界值是否能提高检测率？

Minerva gastroenterology Pub Date : 2023-12-01 Epub Date: 2022-03-28 DOI: 10.23736/S2724-5985.22.03124-2

Inayat Gill, Christienne Shams, Angy Hanna, Julie George, Laith H Jamil, Atulkumar Patel

{"title":"Role of demographics in noninvasive testing for colorectal cancer screening: do targeted cut-off values improve detection?","authors":"Inayat Gill, Christienne Shams, Angy Hanna, Julie George, Laith H Jamil, Atulkumar Patel","doi":"10.23736/S2724-5985.22.03124-2","DOIUrl":"10.23736/S2724-5985.22.03124-2","url":null,"abstract":"Background: Fecal immunochemical test (FIT) is a yearly alternative colorectal screening modality for average risk individuals unwilling or unable to undergo invasive colorectal cancer (CRC) screening due to cost and accessibility. This study aimed to determine whether FIT should be interpreted within the context of patient demographics and medical history.Methods: Patients >50 years old who had a FIT followed by colonoscopy within 1 year were analyzed based on age, race, BMI, social and medical comorbidities. False positive (FP) and false negative (FN) FIT results within each patient demographic and medical history variable were determined by comparing with the gold standard of colonoscopy using χ2 analysis.Results: One thousand twenty-five patients were reviewed. 21.8% of FIT results were positive. Factors which differed in positive FIT rates were age (P=0.003), smoking (P<0.001), alcohol (P=0.001), and hypertension (P<0.001). The difference in rates of FP and FN FIT outcomes among each variable underwent further subanalysis. The FP was 66.8% and the FN rate was 12.8%. Higher FN outcomes were noted in those above 70, males and smokers, though the result was only statistically significant for males (P=0.009). Females were observed to have higher FP rates (P=0.019).Conclusions: Females had higher FP FIT rates compared to males, indicating that sex may influence FIT outcomes and should be accounted for when interpreting FIT results. This information can be utilized to identify populations at higher risk of FP or FN FIT results to target CRC screening. Additionally, recalculating the FP and FN rates for each variable may help determine new FIT targets.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":"69 4","pages":"459-469"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and safety of video-assisted anal fistula treatment in anorectal fistula: a meta-analysis. 肛门直肠瘘视频辅助肛瘘治疗的有效性和安全性：一项荟萃分析。

Minerva gastroenterology Pub Date : 2023-12-01 DOI: 10.23736/S2724-5985.21.02925-9

Chunqiang Wang, Tianye Huang, Xuebing Wang

{"title":"Efficacy and safety of video-assisted anal fistula treatment in anorectal fistula: a meta-analysis.","authors":"Chunqiang Wang, Tianye Huang, Xuebing Wang","doi":"10.23736/S2724-5985.21.02925-9","DOIUrl":"10.23736/S2724-5985.21.02925-9","url":null,"abstract":"Introduction: By searching relevant literature, the recurrence rate, complication rate after video-assisted anal fistula treatment (VAAFT), and efficacy and safety of the treatment were analyzed.Evidence acquisition: Articles that reported the outcomes of VAAFT up to December 2020 were searched in PubMed (Medline) and Cochrane Library, in accordance with the preferred reporting items for systematic review and meta-analysis (PRISMA) screening guidelines. Two researchers independently completed the whole process from screening and inclusion to quality evaluation and bias risk assessment, and the data was included in the RevMan 5.3 software for analysis. The main outcomes were demographic data of patients, detection rate, classification of internal opening of anorectal fistula, postoperative recurrence rate, and incidence of complications.Evidence synthesis: A total of 10 articles were included (779 patients). The average age of the patients was 44 years old, average operation time was 60 min, and the average follow-up time was 22 months. The ratio of male to female was 2.4:1, the ratio of high anorectal fistula to low anorectal fistula was 6.6:1, the detection rate of internal openings was 98%, the weighted recurrence rate was 24%, and the weighted complication rate was 1%.Conclusions: VAAFT is effective and safe in the treatment of anorectal fistulas.","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":"69 4","pages":"529-536"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139405786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Psychological distress trend in non-celiac gluten sensitivity: is there a role for a gliadin-degrading probiotic strain? 非乳糜泻谷蛋白敏感性的心理困扰趋势：降解醇溶蛋白的益生菌菌株有作用吗？

Minerva gastroenterology Pub Date : 2023-12-01 Epub Date: 2023-09-21 DOI: 10.23736/S2724-5985.23.03560-X

Francesco DI Pierro, Gianna Agnelli, Diana M Conti, Antonella DI Maggio, Silvia C Tomaino, Maria R Ingenito, Alessandra Piontini, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Luisella Vigna

引用次数: 0

Correction to: Intestinal fat absorption shifting: polyglucosamine biopolymer controls lipids and weight and reduces the progression of subclinical atherosclerosis. 更正：肠道脂肪吸收转移：聚葡萄糖胺生物聚合物可控制血脂和体重，减少亚临床动脉粥样硬化的发展。

IF 1.9

Minerva gastroenterology Pub Date : 2023-12-01 DOI: 10.23736/S2724-5985.23.03598-2

Gianni Belcaro, Umberto Cornelli, Morio Hosoi, David Cox, Mark Dugall, Maria R Cesarone, Andrea Ledda, Valeria Scipione, Claudia Scipione, Beatrice Feragalli, Roberto Cotellese

引用次数: 0