Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2024-03-06DOI: 10.23736/S2724-5985.24.03581-2
Pauline Jouët, Claude Altman, Stanislas Bruley DES Varannes, Christine Juhel, Franck Henri
{"title":"Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study.","authors":"Pauline Jouët, Claude Altman, Stanislas Bruley DES Varannes, Christine Juhel, Franck Henri","doi":"10.23736/S2724-5985.24.03581-2","DOIUrl":"10.23736/S2724-5985.24.03581-2","url":null,"abstract":"<p><strong>Background: </strong>Patients with irritable bowel syndrome (IBS) experience recurrent symptoms and anxiety disorders that significantly impact their quality of life (QoL). The aim of the study was to assess in daily practice the benefit of the combination of three probiotic strains (Lactobacillus plantarum CETC 7484 and CETC 7485; Pediococcus acidilactici CECT 7483) plus vitamin D in patients with diarrhea-predominant IBS (IBS-D) or IBS with mixed bowel movements (IBS-M).</p><p><strong>Methods: </strong>This was a prospective, multicenter, non-interventional study in adult patients with IBS-D or IBS-M (Rome IV criteria) followed by private-practice gastroenterologists. Patients received daily one sachet of a combination of probiotics (3×10<sup>9</sup> CFU) and vitamin D (10 μg) for 42 days. The primary endpoint was the responder rate at D42 (≥50% and/or ≥100-point decrease of IBS-Severity Scoring System; IBS-SSS). Gut-related anxiety was measured with the Visceral Sensitivity Index (VSI).</p><p><strong>Results: </strong>The full analysis set population included 246 patients (mean age, 51.2±15.4 years; women, 73.2%; IBS-D, 56.1%; IBS-M, 43.9%). At D42, among the 89 patients with evaluable data, the responder rate was 62.9% with a mean decrease of IBS-SSS of 146.6±125.9 (P<0.0001). Changes of IBS-SSS were significantly correlated with changes of IBS-QoL (r=-0.78; P<0.0001), HAD-anxiety (r=0.46; P<0.0001), HAD-depression (r=0.61; P<0.001) and VSI (r=0.74; P<0.0001).</p><p><strong>Conclusions: </strong>These real-life results are in line with a previous randomized clinical trial demonstrating the benefits of this combination in IBS-D and IBS-M. Symptom relief was associated with improvement of IBS-QoL, anxiety, depression and specifically gut-related anxiety.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"332-341"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140041210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2023-10-27DOI: 10.23736/S2724-5985.23.03526-X
Zhongpeng Zhu, Yongsheng Li
{"title":"Application analysis of enteral immune nutritional support in postoperative radiotherapy and chemotherapy patients with colorectal cancer.","authors":"Zhongpeng Zhu, Yongsheng Li","doi":"10.23736/S2724-5985.23.03526-X","DOIUrl":"10.23736/S2724-5985.23.03526-X","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"390-392"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54232971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2023-10-05DOI: 10.23736/S2724-5985.23.03396-X
Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi
{"title":"Diagnostic accuracy of antiendomysial antibodies biopsy test for celiac disease in clinical practice.","authors":"Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi","doi":"10.23736/S2724-5985.23.03396-X","DOIUrl":"10.23736/S2724-5985.23.03396-X","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of celiac disease (CD) is still challenging and tests that show an activation of the immune system against gluten are required. IgA antiendomysial antibodies detection in the supernatant of intestinal biopsies by immunofluorescence technique (AEA-biopsy) is a promising diagnostic tool. The aim of the present study was to evaluate the diagnostic accuracy of AEA-biopsy in a pediatric population with suspected CD.</p><p><strong>Methods: </strong>All children who underwent upper gastrointestinal endoscopy at the Unit of Pediatrics of Treviso Hospital were enrolled and divided into 4 groups: classical CD, CD excluded, potential CD and control group. For each patient, serum autoantibodies and histological evaluation were determined. Two additional biopsy samples were taken to test for presence of AEA.</p><p><strong>Results: </strong>A total of 92 patients were enrolled. All the classical CD cases (38) had a positive AEA-biopsy. In the CD excluded group (10 in total) AEA-biopsy was negative in all patients except 1. Among potential CD patients (which were 14), AEA-biopsy was negative in 4. In the control group (30 patients) AEA-biopsy was negative in all patients except 1. The sensitivity and specificity of AEA-biopsy were 100% and 96% respectively.</p><p><strong>Conclusions: </strong>AEA-biopsy has an excellent diagnostic accuracy in a routine clinical setting.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"291-298"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the effect of PDCA nursing management on patient prevention complications and satisfaction after laser surgery in plastic and aesthetic clinics.","authors":"Chunyan Huang, Suping Lin, Shuhong Ge, Jingjing Xu","doi":"10.23736/S2724-5985.23.03443-5","DOIUrl":"10.23736/S2724-5985.23.03443-5","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"376-378"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo D'Agruma, Leonardo D'Agruma, Pamela Piscitelli, Paola Parente, Paolo Graziano, Gianluigi Vendemiale, Marco Castori, Giovanni B Gasbarrini, Salvatore DE Cosmo, Antonio Mirijello
{"title":"Markedly raised CA 19-9 levels in an asymptomatic patient: the role of Helicobacter pylori infection.","authors":"Angelo D'Agruma, Leonardo D'Agruma, Pamela Piscitelli, Paola Parente, Paolo Graziano, Gianluigi Vendemiale, Marco Castori, Giovanni B Gasbarrini, Salvatore DE Cosmo, Antonio Mirijello","doi":"10.23736/S2724-5985.24.03704-5","DOIUrl":"https://doi.org/10.23736/S2724-5985.24.03704-5","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-06-01Epub Date: 2024-03-26DOI: 10.23736/S2724-5985.24.03634-9
Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi
{"title":"Probiotic mixture in patients after Helicobacter pylori eradication: a real-life experience.","authors":"Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi","doi":"10.23736/S2724-5985.24.03634-9","DOIUrl":"10.23736/S2724-5985.24.03634-9","url":null,"abstract":"<p><strong>Background: </strong>Eradication for Helicobacter pylori usually induces digestive dysbiosis that, in turn, elicits symptoms. Consequently, probiotic supplementation may counterbalance the disturbed microbiota after this procedure. So, probiotics may restore microbiota homeostasis quickly relieve complaints.</p><p><strong>Methods: </strong>The current study evaluated the efficacy and safety of Abivisor<sup>®</sup>, a food supplement containing Lacticaseibacillus rhamnosus LR06 (3 billion living cells), Lactiplantibacillus pentosus LPS01(100 million living cells), Lactiplantibacillus plantarum LP01 (1 billion living cells), and N-acetyl cysteine (60 mg). Patients were randomized into two groups (2:1). Group A took one stick/daily for 60 days after eradication. Group B was considered as control. Patients were evaluated at baseline (T0) and after 15 (T1), 30 (T2), and 60 (T3) days. The severity of digestive symptoms was measured by patients using a Visual Analog Scale. The percentage of patients with each symptom was also evaluated.</p><p><strong>Results: </strong>Abivisor<sup>®</sup> has significantly and progressively diminished intestinal symptoms' presence and severity at T1, T2, and even more at T3. Accordingly, the percentage of symptomatic patients diminished more rapidly and significantly in group A than in B. All patients well tolerated the food supplement.</p><p><strong>Conclusions: </strong>The present study suggests that Abivisor<sup>®</sup> may be an effective and safe therapeutic option for managing patients undergoing H. pylori eradication.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"197-207"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-06-01Epub Date: 2024-03-14DOI: 10.23736/S2724-5985.24.03647-7
Umberto Pacetti, Francesco DI Pierro, Massimiliano Cazzaniga, Ilaria Cavecchia, Mariarosaria Matera, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Simonetta C Stani
{"title":"Can a combination of probiotics and nutraceuticals help preventing the abemaciclib-related diarrhea in breast cancer patients?","authors":"Umberto Pacetti, Francesco DI Pierro, Massimiliano Cazzaniga, Ilaria Cavecchia, Mariarosaria Matera, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Simonetta C Stani","doi":"10.23736/S2724-5985.24.03647-7","DOIUrl":"10.23736/S2724-5985.24.03647-7","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"242-244"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Salvatore E Aragona, Cristiano Spada, Luca DE Luca, Elena Aragona, Giorgio Ciprandi
{"title":"Probiotics for managing patients after bowel preparation for colonoscopy: an interventional, double-arm, open, randomized, multi-center, and national study (COLONSTUDY).","authors":"Salvatore E Aragona, Cristiano Spada, Luca DE Luca, Elena Aragona, Giorgio Ciprandi","doi":"10.23736/S2724-5985.24.03630-1","DOIUrl":"10.23736/S2724-5985.24.03630-1","url":null,"abstract":"<p><strong>Background: </strong>Bowel preparation (BP) for colonoscopy induces significant changes in gut microbiota, causing dysbiosis that, in turn, elicits intestinal symptoms. Consequently, probiotics may counterbalance the disturbed microbiota after BP. So, probiotics may restore microbiota homeostasis.</p><p><strong>Methods: </strong>The current study evaluated the efficacy and safety of Abincol<sup>®</sup>, an oral nutraceutical containing a probiotic mixture with Lactobacillus plantarum LP01 (1 billion living cells), Lactobacillus lactis subspecies cremoris LLC02 (800 millions living cells), and Lactobacillus delbrueckii LDD01 (200 millions living cells), Patients were randomized in two groups (2:1). Group A took one stick/daily for four weeks after colonoscopy. Group B was considered as control. Patients were evaluated at baseline (T0) and after one (T1), two (T2), and four (T3) weeks. The severity of symptoms was measured by patients using a Visual Analog Scale.</p><p><strong>Results: </strong>Abincol<sup>®</sup> significantly diminished the presence and the severity of intestinal symptoms at T2 and even more at T3. All patients well tolerated the probiotic mixture.</p><p><strong>Conclusions: </strong>The present study suggests that Abincol<sup>®</sup> may be considered an effective and safe therapeutic option in managing patients undergoing BP. The course should last one month.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":"70 2","pages":"187-196"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141181759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-06-01Epub Date: 2024-02-06DOI: 10.23736/S2724-5985.24.03648-9
Ludovico Abenavoli, Giuseppe G M Scarlata, Roman Myazin, Dmitry Emelyanov
{"title":"Gastrointestinal symptoms, dietary regimen and anxiety levels during the COVID-19 pandemic among medical students: results from a web-based survey.","authors":"Ludovico Abenavoli, Giuseppe G M Scarlata, Roman Myazin, Dmitry Emelyanov","doi":"10.23736/S2724-5985.24.03648-9","DOIUrl":"10.23736/S2724-5985.24.03648-9","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"244-245"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139693810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}