Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2023-12-21DOI: 10.23736/S2724-5985.23.03593-3
Miao Yu
{"title":"Analysis of combined testing results of ALB, CHE, and γ-GT levels in patients with cirrhosis.","authors":"Miao Yu","doi":"10.23736/S2724-5985.23.03593-3","DOIUrl":"10.23736/S2724-5985.23.03593-3","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"395-397"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138833781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2024-03-26DOI: 10.23736/S2724-5985.23.03480-0
Maria C Conti Bellocchi, Enrico Gasparini, Serena DI Stefano, Valentina Bobba, Laura Bernardoni, Viola Fino, Stefano F Crinò, Armando Gabbrielli
{"title":"The real-time analysis of gastric juice (Endofaster) for detection of Helicobacter Pylori: a reliable tool in substitution of histology.","authors":"Maria C Conti Bellocchi, Enrico Gasparini, Serena DI Stefano, Valentina Bobba, Laura Bernardoni, Viola Fino, Stefano F Crinò, Armando Gabbrielli","doi":"10.23736/S2724-5985.23.03480-0","DOIUrl":"10.23736/S2724-5985.23.03480-0","url":null,"abstract":"<p><strong>Background: </strong>EndoFaster perform gastric juice analysis providing real-time Helicobacter pylori (HP) diagnosis during esophagogastroduodenoscopy (EGD), based on ammonium level. We aimed to assess its accuracy in detecting HP infection compared to the paired histology and to establish the optimum ammonium concentration cut-off point (COP).</p><p><strong>Methods: </strong>Consecutive adult outpatients referred for EGD were prospectively enrolled between December 2021 and March 2022. In-patients, those with surgically altered anatomy, suspected neoplasia, and bleeding were excluded. EndoFaster and histology were performed in all patients, with additional stool antigen test (SAT) reserved for discordant cases. EndoFaster diagnostic measures were calculated, and ammonium level COP established using AUROC curve analysis.</p><p><strong>Results: </strong>101 patients (64 female, mean age 56.7±16.1 years) were included. HP infection was diagnosed in 35 (34.6%) and 15 (14.8%) patients by EndoFaster and histology, respectively. Diagnostic accuracy in comparison with histology was 77.8% (95%CI 68.3% - 85.5%). After implementing SAT for gold standard assessment, EndoFaster accuracy increased to 81.6% (95%CI 72.5%-88.7%). AUROC curve (0.93±0.03, 95%CI 0.86-0.99) identified an ammonium COP of ≥67.5ppm. Using the new COP, EndoFaster accuracy further increased to 88.8% (95%CI 80.8%-94.2%).</p><p><strong>Conclusions: </strong>Endofaster showed high accuracy for HP detection, with moderate agreement to histology. An ammonium COP of 67.5 ppm seems to be the threshold with the highest accuracy for HP detection.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"315-321"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2024-03-06DOI: 10.23736/S2724-5985.24.03581-2
Pauline Jouët, Claude Altman, Stanislas Bruley DES Varannes, Christine Juhel, Franck Henri
{"title":"Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study.","authors":"Pauline Jouët, Claude Altman, Stanislas Bruley DES Varannes, Christine Juhel, Franck Henri","doi":"10.23736/S2724-5985.24.03581-2","DOIUrl":"10.23736/S2724-5985.24.03581-2","url":null,"abstract":"<p><strong>Background: </strong>Patients with irritable bowel syndrome (IBS) experience recurrent symptoms and anxiety disorders that significantly impact their quality of life (QoL). The aim of the study was to assess in daily practice the benefit of the combination of three probiotic strains (Lactobacillus plantarum CETC 7484 and CETC 7485; Pediococcus acidilactici CECT 7483) plus vitamin D in patients with diarrhea-predominant IBS (IBS-D) or IBS with mixed bowel movements (IBS-M).</p><p><strong>Methods: </strong>This was a prospective, multicenter, non-interventional study in adult patients with IBS-D or IBS-M (Rome IV criteria) followed by private-practice gastroenterologists. Patients received daily one sachet of a combination of probiotics (3×10<sup>9</sup> CFU) and vitamin D (10 μg) for 42 days. The primary endpoint was the responder rate at D42 (≥50% and/or ≥100-point decrease of IBS-Severity Scoring System; IBS-SSS). Gut-related anxiety was measured with the Visceral Sensitivity Index (VSI).</p><p><strong>Results: </strong>The full analysis set population included 246 patients (mean age, 51.2±15.4 years; women, 73.2%; IBS-D, 56.1%; IBS-M, 43.9%). At D42, among the 89 patients with evaluable data, the responder rate was 62.9% with a mean decrease of IBS-SSS of 146.6±125.9 (P<0.0001). Changes of IBS-SSS were significantly correlated with changes of IBS-QoL (r=-0.78; P<0.0001), HAD-anxiety (r=0.46; P<0.0001), HAD-depression (r=0.61; P<0.001) and VSI (r=0.74; P<0.0001).</p><p><strong>Conclusions: </strong>These real-life results are in line with a previous randomized clinical trial demonstrating the benefits of this combination in IBS-D and IBS-M. Symptom relief was associated with improvement of IBS-QoL, anxiety, depression and specifically gut-related anxiety.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"332-341"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140041210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2023-10-27DOI: 10.23736/S2724-5985.23.03526-X
Zhongpeng Zhu, Yongsheng Li
{"title":"Application analysis of enteral immune nutritional support in postoperative radiotherapy and chemotherapy patients with colorectal cancer.","authors":"Zhongpeng Zhu, Yongsheng Li","doi":"10.23736/S2724-5985.23.03526-X","DOIUrl":"10.23736/S2724-5985.23.03526-X","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"390-392"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54232971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-09-01Epub Date: 2023-10-05DOI: 10.23736/S2724-5985.23.03396-X
Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi
{"title":"Diagnostic accuracy of antiendomysial antibodies biopsy test for celiac disease in clinical practice.","authors":"Elisa Benelli, Giulia Zavarise, Paolo M Pavanello, Federica Mario, Giuseppina Barberio, Marco Gasparella, Francesca Galuppini, Ivana Cataldo, Maria Guido, Anna C Frigo, Stefano Martelossi","doi":"10.23736/S2724-5985.23.03396-X","DOIUrl":"10.23736/S2724-5985.23.03396-X","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of celiac disease (CD) is still challenging and tests that show an activation of the immune system against gluten are required. IgA antiendomysial antibodies detection in the supernatant of intestinal biopsies by immunofluorescence technique (AEA-biopsy) is a promising diagnostic tool. The aim of the present study was to evaluate the diagnostic accuracy of AEA-biopsy in a pediatric population with suspected CD.</p><p><strong>Methods: </strong>All children who underwent upper gastrointestinal endoscopy at the Unit of Pediatrics of Treviso Hospital were enrolled and divided into 4 groups: classical CD, CD excluded, potential CD and control group. For each patient, serum autoantibodies and histological evaluation were determined. Two additional biopsy samples were taken to test for presence of AEA.</p><p><strong>Results: </strong>A total of 92 patients were enrolled. All the classical CD cases (38) had a positive AEA-biopsy. In the CD excluded group (10 in total) AEA-biopsy was negative in all patients except 1. Among potential CD patients (which were 14), AEA-biopsy was negative in 4. In the control group (30 patients) AEA-biopsy was negative in all patients except 1. The sensitivity and specificity of AEA-biopsy were 100% and 96% respectively.</p><p><strong>Conclusions: </strong>AEA-biopsy has an excellent diagnostic accuracy in a routine clinical setting.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"291-298"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41159036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of the effect of PDCA nursing management on patient prevention complications and satisfaction after laser surgery in plastic and aesthetic clinics.","authors":"Chunyan Huang, Suping Lin, Shuhong Ge, Jingjing Xu","doi":"10.23736/S2724-5985.23.03443-5","DOIUrl":"10.23736/S2724-5985.23.03443-5","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"376-378"},"PeriodicalIF":1.9,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41180800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angelo D'Agruma, Leonardo D'Agruma, Pamela Piscitelli, Paola Parente, Paolo Graziano, Gianluigi Vendemiale, Marco Castori, Giovanni B Gasbarrini, Salvatore DE Cosmo, Antonio Mirijello
{"title":"Markedly raised CA 19-9 levels in an asymptomatic patient: the role of Helicobacter pylori infection.","authors":"Angelo D'Agruma, Leonardo D'Agruma, Pamela Piscitelli, Paola Parente, Paolo Graziano, Gianluigi Vendemiale, Marco Castori, Giovanni B Gasbarrini, Salvatore DE Cosmo, Antonio Mirijello","doi":"10.23736/S2724-5985.24.03704-5","DOIUrl":"https://doi.org/10.23736/S2724-5985.24.03704-5","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-06-01Epub Date: 2024-03-26DOI: 10.23736/S2724-5985.24.03634-9
Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi
{"title":"Probiotic mixture in patients after Helicobacter pylori eradication: a real-life experience.","authors":"Salvatore E Aragona, Carlo Fabbri, Giovanni Cammarota, Giorgio Ciprandi","doi":"10.23736/S2724-5985.24.03634-9","DOIUrl":"10.23736/S2724-5985.24.03634-9","url":null,"abstract":"<p><strong>Background: </strong>Eradication for Helicobacter pylori usually induces digestive dysbiosis that, in turn, elicits symptoms. Consequently, probiotic supplementation may counterbalance the disturbed microbiota after this procedure. So, probiotics may restore microbiota homeostasis quickly relieve complaints.</p><p><strong>Methods: </strong>The current study evaluated the efficacy and safety of Abivisor<sup>®</sup>, a food supplement containing Lacticaseibacillus rhamnosus LR06 (3 billion living cells), Lactiplantibacillus pentosus LPS01(100 million living cells), Lactiplantibacillus plantarum LP01 (1 billion living cells), and N-acetyl cysteine (60 mg). Patients were randomized into two groups (2:1). Group A took one stick/daily for 60 days after eradication. Group B was considered as control. Patients were evaluated at baseline (T0) and after 15 (T1), 30 (T2), and 60 (T3) days. The severity of digestive symptoms was measured by patients using a Visual Analog Scale. The percentage of patients with each symptom was also evaluated.</p><p><strong>Results: </strong>Abivisor<sup>®</sup> has significantly and progressively diminished intestinal symptoms' presence and severity at T1, T2, and even more at T3. Accordingly, the percentage of symptomatic patients diminished more rapidly and significantly in group A than in B. All patients well tolerated the food supplement.</p><p><strong>Conclusions: </strong>The present study suggests that Abivisor<sup>®</sup> may be an effective and safe therapeutic option for managing patients undergoing H. pylori eradication.</p>","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"197-207"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140295742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Minerva gastroenterologyPub Date : 2024-06-01Epub Date: 2024-03-14DOI: 10.23736/S2724-5985.24.03647-7
Umberto Pacetti, Francesco DI Pierro, Massimiliano Cazzaniga, Ilaria Cavecchia, Mariarosaria Matera, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Simonetta C Stani
{"title":"Can a combination of probiotics and nutraceuticals help preventing the abemaciclib-related diarrhea in breast cancer patients?","authors":"Umberto Pacetti, Francesco DI Pierro, Massimiliano Cazzaniga, Ilaria Cavecchia, Mariarosaria Matera, Alexander Bertuccioli, Nicola Zerbinati, Luigina Guasti, Simonetta C Stani","doi":"10.23736/S2724-5985.24.03647-7","DOIUrl":"10.23736/S2724-5985.24.03647-7","url":null,"abstract":"","PeriodicalId":94142,"journal":{"name":"Minerva gastroenterology","volume":" ","pages":"242-244"},"PeriodicalIF":1.9,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140121712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}