Journal of biophotonics最新文献_第5页

Exploratory Raman Spectroscopic Studies of Canine Oral Tumour Types.

Journal of biophotonics Pub Date : 2025-02-09 DOI: 10.1002/jbio.202400372

Priyanka A Jadhav, Arti Hole, Panchali Saha, Kshama Pansare, Aishwarya Ghanwat, Poonam Gera, Kiran Bendale, C Murali Krishna, Pradip Chaudhari

{"title":"Exploratory Raman Spectroscopic Studies of Canine Oral Tumour Types.","authors":"Priyanka A Jadhav, Arti Hole, Panchali Saha, Kshama Pansare, Aishwarya Ghanwat, Poonam Gera, Kiran Bendale, C Murali Krishna, Pradip Chaudhari","doi":"10.1002/jbio.202400372","DOIUrl":"https://doi.org/10.1002/jbio.202400372","url":null,"abstract":"Canine cancers are becoming increasingly significant due to their natural occurrence, similar to the spontaneous cancers in humans as well as their histological and biological similarities to human cancers. Several oral cancer types have been witnessed in dogs, based on the cell type from which the tumour originates. The type of oral tumour dictates severity of the disease, treatment options and prognoses. The current tissue-based Raman Spectroscopy (RS) study explores stratification of canine cancers. Raman spectra of histopathologically confirmed normal and oral tumour types namely Epulis, Spindle cell sarcoma (SCS), and Squamous cell carcinoma (SCC) were acquired using a Raman confocal microscope with 532 nm laser, pre-processed and multivariate analyses performed. PC-LDA achieved overall classification accuracy of > 70%. Thus, the present study evaluates potential of RS to identify the tumour type based on the identification of characteristic spectral features. Findings warrant large scale in vivo RS explorations in canine cancer subjects.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202400372"},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143384417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Hair Regrowth Through Dual-Wavelength Low-Level Laser Therapy: A Comparative Study on Mice.

Journal of biophotonics Pub Date : 2025-02-09 DOI: 10.1002/jbio.202400523

He Gao, Yao Liu, Zhaiyi Liu, Pengquan Wang, Zhaoyin Qin, Shuanglin Liao, Jia Mo, Lin Wang, Hsiang-Chen Chui

引用次数: 0

Enhanced Photothermal Tumor Ablation Using Polypyrrole-Gold Nanocomposites Activated by Polarized Polychromatic Low-Energy Light: An In Vivo Study.

Journal of biophotonics Pub Date : 2025-02-06 DOI: 10.1002/jbio.202400488

Jilan S Ibrahim, Neamat Hanafi, Mahmoud A Sliem, Tarek A El-Tayeb

{"title":"Enhanced Photothermal Tumor Ablation Using Polypyrrole-Gold Nanocomposites Activated by Polarized Polychromatic Low-Energy Light: An In Vivo Study.","authors":"Jilan S Ibrahim, Neamat Hanafi, Mahmoud A Sliem, Tarek A El-Tayeb","doi":"10.1002/jbio.202400488","DOIUrl":"https://doi.org/10.1002/jbio.202400488","url":null,"abstract":"Photothermal therapy (PTT) offers a minimally invasive approach for cancer treatment, using light energy to selectively heat and destroy cancer cells. Success in PTT depends on efficient, stable, and biocompatible photothermal agents. This study investigates polypyrrole@gold nanocomposites (PPy@Au NCs) as photothermal agents combined with polarized polychromatic low-energy light (PPLEL) to target tumors and limit disease progression. In vivo experiments on Ehrlich carcinoma-bearing female Swiss albino mice demonstrated that PPy@Au NCs selectively accumulated in tumor tissue and, when activated by PPLEL, generated sufficient heat for effective tumor ablation. This approach enhanced treatment efficacy and presented a cost-effective solution due to the affordability of both the nanocomposite and light source. Histopathological analysis confirmed significant tumor reduction, suggesting that this synergistic combination offers a promising cancer treatment strategy. Findings support further research and potential clinical applications in photothermal cancer therapy.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202400488"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Study Into the Effect of Detector Noises and Sensitivity on the Serum SERS Analysis: Example of Non-Communicable Diseases Discrimination.

Journal of biophotonics Pub Date : 2025-02-06 DOI: 10.1002/jbio.202400475

Lyudmila A Bratchenko, Yulia A Khristoforova, Irina A Pimenova, Mikhail S Snegerev, Vitaly I Kupaev, Petr A Lebedev, Yuri V Kistenev, Ivan A Bratchenko

{"title":"Comparative Study Into the Effect of Detector Noises and Sensitivity on the Serum SERS Analysis: Example of Non-Communicable Diseases Discrimination.","authors":"Lyudmila A Bratchenko, Yulia A Khristoforova, Irina A Pimenova, Mikhail S Snegerev, Vitaly I Kupaev, Petr A Lebedev, Yuri V Kistenev, Ivan A Bratchenko","doi":"10.1002/jbio.202400475","DOIUrl":"https://doi.org/10.1002/jbio.202400475","url":null,"abstract":"The aim of the study is to compare the performance of surface-enhanced Raman spectroscopy (SERS) analysis of serum using a non-cooled detector (EnSpectr R785) and a high spectral resolution detector (Renishaw) in the task of discrimination between the patients with chronic heart failure and the patients with chronic obstructive pulmonary disease. The SERS-based solution of the classification problem demonstrates an insignificant relationship between the disease classification accuracy and detector quality (classification accuracy for the high-resolution setup is 0.84 and for the low-cost setup is 0.81). In the data recorded on Renishaw setup, the most significant bands are 611, 675, 720, 804, 1187, 1495, and 1847 cm-1; for the EnSpectr setup-721, 1051, and 1665 cm-1. The results have revealed equal discrimination capabilities in the EnSpectr and the Renishaw setups; however, the Renishaw setup has more prospects for identifying the spectral contribution of pathologically associated analytes.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202400475"},"PeriodicalIF":0.0,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laser-Induced Minimization of Circulating Tumor Cells to Suppress Tumor Metastasis.

Journal of biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400569

Da Sun, Bingchen Yu, Rui Xu, Chenzheng Wang, Kai Pang

引用次数: 0

Fast In Vivo Two-Photon Fluorescence Imaging via Lateral and Axial Resolution Restoration With Self-Supervised Learning.

Journal of biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400489

Zhengyuan Pan, Man Lei, Hongen Liao, Bobo Gu

引用次数: 0

A Compact Prism-Based Microscope for Highly Sensitive Measurements in Fluid Biopsy.

Journal of biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400519

Laura Perego, Caterina Dallari, Chiara Falciani, Alessandro Pini, Lucia Gardini, Caterina Credi, Francesco Saverio Pavone

{"title":"A Compact Prism-Based Microscope for Highly Sensitive Measurements in Fluid Biopsy.","authors":"Laura Perego, Caterina Dallari, Chiara Falciani, Alessandro Pini, Lucia Gardini, Caterina Credi, Francesco Saverio Pavone","doi":"10.1002/jbio.202400519","DOIUrl":"https://doi.org/10.1002/jbio.202400519","url":null,"abstract":"The increasing demand for sensitive, portable, and affordable disease detection methods has spurred the development of advanced biosensors for rapid early-stage diagnosis, population mass screening, and bed-monitoring. Current high-sensitivity devices face hurdles such as high production costs and challenges in multiplexed signal detection. To address these, we developed a prism-based total internal reflection system which, in combination with surface functionalization techniques of gold nanoparticles, enables evanescent wave scattering for highly sensitive and rapid detection of specific analytes in both synthetic and human liquid samples. To validate its efficacy, we conducted scattering experiments in synthetic and human serum samples, exploiting functionalized AuNPs to recognize bacterial lipopolysaccharides as biomarkers for sepsis disease. We demonstrate a remarkable sensitivity in the femtogram per mL concentration range for this specific pathological biomarker. Based on this result we envisage the potential adoption of our technique for liquid biopsy in the clinical scenario.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202400519"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143257656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Digital Cytometry: Extraction of Forward and Side Scattering Signals From Holotomography. 数字细胞测量：从 Holotomography 提取正向和侧向散射信号。

Journal of biophotonics Pub Date : 2025-02-05 DOI: 10.1002/jbio.202400387

Jaepil Jo, Herve Hugonnet, Mahn Jae Lee, YongKeun Park

引用次数: 0

Correction of Non-Uniform Rotational Distortion in the Proximally Controlled Endoscopic OCTA.

Journal of biophotonics Pub Date : 2025-02-04 DOI: 10.1002/jbio.202400467

Zehua Guan, Qiang Li, Chen Niu, Shuhao Fan, Huanhuan Yu, Wenjuan Wu, Xiangfei Feng, Cuixia Dai

{"title":"Correction of Non-Uniform Rotational Distortion in the Proximally Controlled Endoscopic OCTA.","authors":"Zehua Guan, Qiang Li, Chen Niu, Shuhao Fan, Huanhuan Yu, Wenjuan Wu, Xiangfei Feng, Cuixia Dai","doi":"10.1002/jbio.202400467","DOIUrl":"https://doi.org/10.1002/jbio.202400467","url":null,"abstract":"Endoscopic Optical Coherence Tomography (OCT) can provide high-resolution cross-sectional images for internal organ tissues. Combining the endoscopic imaging with Optical Coherence Tomography Angiography (OCTA), information of blood vessels in superficial lumen tissues is expected to be acquired. However, in endoscopic OCT systems using proximal scanning probes, performance of OCTA encounters significant challenges due to non-uniform rotational distortion (NURD) caused by the non-constant rotation of the distal imaging unit. In this study, we proposed a registration method for endoscopic OCTA imaging in a proximally controlled OCT System. Global registration and A-line registration were employed to correct the distortion caused by mechanical friction between the catheter sheath and torque coil. Experimental performances in both microfluidic channel and rat rectum show significant correction of NURD. Our study achieved the first implementation of endoscopic OCTA under a spiral B-scan rotation scheme in a proximally controlled OCT system, facilitating clear visualization of blood flow.","PeriodicalId":94068,"journal":{"name":"Journal of biophotonics","volume":" ","pages":"e202400467"},"PeriodicalIF":0.0,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143191558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Fluorescence Imaging of Implants Based on Polyester Copolymers in Combination With MRI.

Journal of biophotonics Pub Date : 2025-02-03 DOI: 10.1002/jbio.202400147

Victoria V Zherdeva, Astemir R Likhov, Ulugbek A Saidvaliev, Dror Fixler, Dmitry Demin, Veronika N Volodina, Uliana A Apukhtina, Shweta Pawar, Bar Atuar, Valery V Tuchin

引用次数: 0