Expert review of medical devices最新文献_第2页

^99mTc-labeled and functionalised plasmonic nanoparticles for photo-thermal therapy of primary tumours. 99mtc标记和功能化等离子体纳米粒子光热治疗原发性肿瘤。

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-04-29 DOI: 10.1080/17434440.2025.2498459

Clelia Raso, Miriam Conte, Francesca Petronella, Viviana Frantellizzi, Flaminia De Cristofaro, Paolo Rosa, Maria Silvia De Feo, Giuseppe De Vincentis, Luciano De Sio

{"title":"99mTc-labeled and functionalised plasmonic nanoparticles for photo-thermal therapy of primary tumours.","authors":"Clelia Raso, Miriam Conte, Francesca Petronella, Viviana Frantellizzi, Flaminia De Cristofaro, Paolo Rosa, Maria Silvia De Feo, Giuseppe De Vincentis, Luciano De Sio","doi":"10.1080/17434440.2025.2498459","DOIUrl":"10.1080/17434440.2025.2498459","url":null,"abstract":"Introduction: Photo-thermal therapy (PTT) is an emerging biomedical field involving plasmonic nanoparticles (NPs), which efficiently convert light into heat due to a phenomenon known as Localized Surface Plasmon Resonance (LSPR). The ease of surface functionalization offered, especially by gold NPs (AuNPs), significantly betters their biocompatibility and stability. The radiolabeling of AuNPs with Technetium-99 (99mTc) allows for their precise spatial localization within the body at any depth and site through nuclear medicine imaging techniques. The combination of radioactive, optical, and thermo-ablative properties makes radiolabelled AuNPs a valid tool in theranostics. This review summarizes the main concepts behind PTT and the most recent clinical applications of plasmonic 99mTc-labeled NPs in cancer theranostic.Areas covered: Literature research of the last 20 years was conducted using Scopus and PubMed, including papers concerning technetium-radiolabelled NPs functionalized for cancer PTT.Expert opinion: AuNPs have been the subject of extensive research for diverse biomedical applications, including cancer diagnostics, therapy, and prevention, as well as drug delivery, sensing and cellular imaging. Despite the limited number of in vivo animal studies, radiolabeling and functionalizing the AuNPs with technetium represents a promising strategy to obtain a specific and efficient theranostic tool for nuclear medicine imaging.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"545-554"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparing for the new wave of intrathecal CNS therapies: innovations in drug delivery devices. 为鞘内中枢神经系统治疗的新浪潮做准备：药物输送装置的创新。

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-04-28 DOI: 10.1080/17434440.2025.2499154

Manuel Menéndez González

引用次数: 0

The potential power of Neuralink - how brain-machine interfaces can revolutionize medicine. 神经连接的潜在力量——脑机接口如何革新医学。

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-04-28 DOI: 10.1080/17434440.2025.2498457

Rahul Kumar, Ethan Waisberg, Joshua Ong, Andrew G Lee

引用次数: 0

Single-port robotic system - a paradigm shift in robot-assisted radical prostatectomy? 单端口机器人系统——机器人辅助根治性前列腺切除术的范式转变？

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-04-28 DOI: 10.1080/17434440.2025.2499661

Oleksii Pisotskyi, Piotr Petrasz, Piotr Zorga, Marcin Gałęski, Paweł Szponar, Krzysztof Koper, Katarzyna Brzeżniakiewicz-Janus, Tomasz Drewa, Krzysztof Kaczmarek, Michał Cezary Czarnogórski, Jan Adamowicz

{"title":"Single-port robotic system - a paradigm shift in robot-assisted radical prostatectomy?","authors":"Oleksii Pisotskyi, Piotr Petrasz, Piotr Zorga, Marcin Gałęski, Paweł Szponar, Krzysztof Koper, Katarzyna Brzeżniakiewicz-Janus, Tomasz Drewa, Krzysztof Kaczmarek, Michał Cezary Czarnogórski, Jan Adamowicz","doi":"10.1080/17434440.2025.2499661","DOIUrl":"10.1080/17434440.2025.2499661","url":null,"abstract":"Introduction: Robotic-assisted radical prostatectomy (RARP) has become a cornerstone in the surgical management of prostate cancer. This study evaluates the potential of the Da Vinci single-port (SP) system, which represents a significant advancement in minimally invasive surgery.Areas covered: A narrative review was conducted using PubMed and Scopus databases to identify relevant studies published between January 2018 and February 2025. Search terms included 'single-port robotic prostatectomy,' 'Da Vinci SP system,' and 'robot-assisted radical prostatectomy.' Studies comparing SP and multi-port (MP) systems were prioritized. The SP system is discussed in terms of its technical innovations, including 360° operative field visualization, integrated optics and instruments, and enhanced depth perception. Clinical benefits, such as reduced blood loss, faster recovery, improved cosmetic outcomes, and reduced surgical trauma, are highlighted. Comparisons are drawn between the SP and multi-port systems, focusing on oncological and functional outcomes, as well as the challenges associated with the SP system's steeper learning curve.Expert opinion: The SP system holds great promise in advancing patient care in RARP, particularly through its minimally invasive approach. While achieving comparable outcomes to MP systems, it uniquely reduces surgical trauma. However, successful implementation requires overcoming technical challenges and adapting to the learning curve. Future research should focus on refining the technology and exploring its long-term impact on clinical outcomes.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"569-579"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical effect of using a lower limb warming blanket combined with dexmedetomidine to prevent postoperative delirium and shivering in elderly patients undergoing spinal surgery. 下肢温毯联合右美托咪定预防老年脊柱手术患者术后谵妄和寒战的临床效果

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-05-07 DOI: 10.1080/17434440.2025.2499149

Wei Fan, Murong Li, Qi Yao, Yanfei Hao, Gaoliang Ji

{"title":"Clinical effect of using a lower limb warming blanket combined with dexmedetomidine to prevent postoperative delirium and shivering in elderly patients undergoing spinal surgery.","authors":"Wei Fan, Murong Li, Qi Yao, Yanfei Hao, Gaoliang Ji","doi":"10.1080/17434440.2025.2499149","DOIUrl":"10.1080/17434440.2025.2499149","url":null,"abstract":"Objective: To observe the clinical effect of using a lower limb warming blanket combined with dexmedetomidine (DEX) to prevent postoperative delirium (POD) and shivering in elderly patients undergoing spinal surgery.Methods: A total of 160 elderly patients undergoing posterior spinal surgery under general anesthesia were selected and divided into a control group (group N), heating group (group T), DEX group (group D) and heating combined with DEX group (group TD), with 40 patients in each group. The intraoperative anesthesia dosage, changes in body temperature and heart rate at different time points (T1-T6) were compared, as well as the occurrence of postoperative shivering and POD in different groups.Results: During the entire procedure, the anesthesia dosage was lower in groups D and TD than in groups N and T (p < 0.05). The body temperature of groups N and D exhibited a downwards trend, which decreased significantly at T2. At T2-T4, the heart rate of groups D and TD was lower than that of groups N and T (p < 0.05).Conclusion: Using a lower limb heating blanket combined with DEX can effectively reduce the incidence of POD and postoperative shivering in elderly patients undergoing spinal surgery.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"625-631"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144052412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cardiac imaging for the detection of ischemia: current status and future perspectives. 心脏成像检测缺血：现状和未来展望。

Expert review of medical devices Pub Date : 2025-06-01 Epub Date: 2025-05-12 DOI: 10.1080/17434440.2025.2500631

Carlos Rodriguez, Laura Pappas, Quang Le Hong, Laura Baquero, Eike Nagel

{"title":"Cardiac imaging for the detection of ischemia: current status and future perspectives.","authors":"Carlos Rodriguez, Laura Pappas, Quang Le Hong, Laura Baquero, Eike Nagel","doi":"10.1080/17434440.2025.2500631","DOIUrl":"10.1080/17434440.2025.2500631","url":null,"abstract":"Introduction: Coronary artery disease is the main cause of mortality worldwide mandating early detection, appropriate treatment, and follow-up. Noninvasive cardiac imaging techniques allow detection of obstructive coronary heart disease by direct visualization of the arteries or myocardial blood flow reduction. These techniques have made remarkable progress since their introduction, achieving high diagnostic precision. This review aims at evaluating these noninvasive cardiac imaging techniques, rendering a thorough overview of diagnostic decision-making for detection of ischemia.Areas covered: We discuss the latest advances in the field such as computed tomography angiography, single-photon emission tomography, positron emission tomography, and cardiac magnetic resonance; their main advantages and disadvantages, their most appropriate use and prospects. For the review, we analyzed the literature from 2009 to 2024 on noninvasive cardiac imaging in the diagnosis of coronary artery disease. The review included the 78 publications considered most relevant, including landmark trials, review articles and guidelines.Expert opinion: The progress in cardiac imaging is anticipated to overcome various limitations such as high costs, radiation exposure, artifacts, and differences in interpretation among observers. It is expected to lead to more automated scanning processes, and with the assistance of artificial intelligence-driven post-processing software, higher accuracy and reproducibility may be attained.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"581-594"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current and future directions for the use of handheld fundus cameras in telehealth. 在远程保健中使用手持式眼底相机的当前和未来方向。

Expert review of medical devices Pub Date : 2025-05-30 DOI: 10.1080/17434440.2025.2508877

Sarah D Cleveland, Mikayla J Baker, Arthur G Erdman, Hossein Nazari

{"title":"Current and future directions for the use of handheld fundus cameras in telehealth.","authors":"Sarah D Cleveland, Mikayla J Baker, Arthur G Erdman, Hossein Nazari","doi":"10.1080/17434440.2025.2508877","DOIUrl":"10.1080/17434440.2025.2508877","url":null,"abstract":"Introduction: A shortage of trained retinal specialists has created a growing need for a telehealth retinal screening alternative. Recent developments in handheld fundus cameras, enhanced by artificial intelligence (AI) and machine learning (ML) methods, have created a promising avenue to satisfy the unmet need for efficient retinal disease screening. This paper discusses the state of current handheld fundus cameras as well as promising future directions.Areas covered: Commercially available handheld fundus cameras and the current and future developments in telehealth retinal screenings using these cameras are discussed. Relevant literature encompassing handheld fundus cameras, diagnostic accuracy, and AI in grading were included. Commercial handheld fundus cameras were targeted in the literature and from their company websites. Additional information was obtained through dialogs with company representatives.Expert opinion: Handheld fundus cameras utilized for telehealth retinal screening have shown success in multiple small-scale studies. To make their usage more widespread, multiple technical, technological, and methodical barriers must be addressed. This can be accomplished by improving the technology, utilizing AI, and developing telehealth guidelines.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"1-9"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Deep learning without borders: recent advances in ultrasound image classification for liver diseases diagnosis. 无边界深度学习：肝脏疾病超声图像分类的最新进展。

Expert review of medical devices Pub Date : 2025-05-30 DOI: 10.1080/17434440.2025.2514764

Midya Yousefzamani, Farshid Babapour Mofrad

{"title":"Deep learning without borders: recent advances in ultrasound image classification for liver diseases diagnosis.","authors":"Midya Yousefzamani, Farshid Babapour Mofrad","doi":"10.1080/17434440.2025.2514764","DOIUrl":"https://doi.org/10.1080/17434440.2025.2514764","url":null,"abstract":"Introduction: Liver diseases are among the top global health burdens. Recently, there has been an increasing significance of diagnostics without discomfort to the patient; among them, ultrasound is the most used. Deep learning, in particular convolutional neural networks, has revolutionized the classification of liver diseases by automatically performing some specific analyses of difficult images.Areas covered: This review summarizes the progress that has been made in deep learning techniques for the classification of liver diseases using ultrasound imaging. It evaluates various models from CNNs to their hybrid versions, such as CNN-Transformer, for detecting fatty liver, fibrosis, and liver cancer, among others. Several challenges in the generalization of data and models across a different clinical environment are also discussed.Expert opinion: Deep learning has great prospects for automatic diagnosis of liver diseases. Most of the models have performed with high accuracy in different clinical studies. Despite this promise, challenges relating to generalization have remained. Future hardware developments and access to quality clinical data continue to further improve the performance of these models and ensure their vital role in the diagnosis of liver diseases.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual performance during night driving after intraocular refractive surgery procedures. 眼内屈光手术后夜间驾驶的视觉表现。

Expert review of medical devices Pub Date : 2025-05-29 DOI: 10.1080/17434440.2025.2512038

Sonia Puente-Bustillo, Alfredo Holgueras, Alberto López-Miguel, Miguel J Maldonado

{"title":"Visual performance during night driving after intraocular refractive surgery procedures.","authors":"Sonia Puente-Bustillo, Alfredo Holgueras, Alberto López-Miguel, Miguel J Maldonado","doi":"10.1080/17434440.2025.2512038","DOIUrl":"10.1080/17434440.2025.2512038","url":null,"abstract":"Introduction: Cataracts reduce visual acuity and contrast sensitivity, and increase photic phenomena, especially at night. Recent advancements in cataract surgery have improved intraocular lens (IOL) designs. Monofocal, multifocal, and extended depth-of-focus IOLs offer different vision ranges but can still cause adverse visual effects like reduced contrast sensitivity and photic phenomena, affecting night driving. Investigating how different IOLs affect night driving is crucial for road safety and quality of life.Areas covered: Studies assessing night driving performance in patients who underwent surgery with monofocal, multifocal, and extended depth-of-focus IOL implantations were included in this review. The following databases were searched to conduct the review: PubMed, Scopus and Web of Science. The level of scientific evidence was graded according to the Scottish Intercollegiate Guidelines Network (SIGN).Expert opinion: Multifocal IOL implantation improves quality of life, however night driving continues to be challenging for some multifocal IOL patients whose neuroadaptation process has not been completed. Therefore, the use of validated questionnaires to adequately assess night driving before and after IOL implantation is highly recommended. Further well-designed randomized clinical trials are needed to objectively assess visual function during night driving. Night driving simulators could provide complementary reliable information to questionnaires' outcomes.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144153036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revolutionizing breast cancer care: the synergy of AI-powered diagnostics, haptic-based biopsy simulators, and advanced surgical techniques. 革新乳腺癌护理：人工智能诊断、基于触觉的活检模拟器和先进手术技术的协同作用。

Expert review of medical devices Pub Date : 2025-05-29 DOI: 10.1080/17434440.2025.2514007

Tanyaradzwa Roselyn Tichiwangana, Qianwen Ji, Xingqi Fan, Tao Ying, Xiaojun Chen

{"title":"Revolutionizing breast cancer care: the synergy of AI-powered diagnostics, haptic-based biopsy simulators, and advanced surgical techniques.","authors":"Tanyaradzwa Roselyn Tichiwangana, Qianwen Ji, Xingqi Fan, Tao Ying, Xiaojun Chen","doi":"10.1080/17434440.2025.2514007","DOIUrl":"https://doi.org/10.1080/17434440.2025.2514007","url":null,"abstract":"Background: In 2022, a report by the World Health Organization revealed 2.3 million new breast cancer cases and 670,000 related deaths, which represented 11.7% of all cancer cases worldwide. Early screening and biopsy for breast cancer can provide more effective and minimally invasive treatment options. As treatment options evolve, breast cancer surgery can ensure cure rate and aesthetics after surgery.Areas covered: This review article examines the latest advancements in breast cancer care, highlighting the integration of artificial intelligence (AI) in diagnostics, the development of haptic-based breast biopsy simulators, and innovative surgical techniques.Expert opinion: AI-driven diagnostic systems have significantly improved the accuracy and effectiveness of breast cancer screening with a precision comparable to that of experienced radiologists. Furthermore, haptic-based breast biopsy simulators are revolutionizing surgical training by providing practitioners with a realistic and safe environment to refine their biopsy techniques and breast surgery skills. Concurrently, advancements in surgical procedures, often augmented by AI and virtual reality (VR) simulations, are transforming breast cancer treatment, which facilitate the practice of complex surgical techniques, potentially resulting in more specialized and minimally invasive procedures. Collectively, these innovations are improving the screening, diagnosis, and surgical results for breast cancer patients.","PeriodicalId":94006,"journal":{"name":"Expert review of medical devices","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144182383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0